{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T04:08:39Z","timestamp":1790741319533,"version":"4.1.0"},"reference-count":67,"publisher":"Public Library of Science (PLoS)","issue":"12","license":[{"start":{"date-parts":[[2013,12,20]],"date-time":"2013-12-20T00:00:00Z","timestamp":1387497600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0082602","type":"journal-article","created":{"date-parts":[[2013,12,20]],"date-time":"2013-12-20T21:30:13Z","timestamp":1387575013000},"page":"e82602","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":70,"title":["Prestin Regulation and Function in Residual Outer Hair Cells after Noise-Induced Hearing Loss"],"prefix":"10.1371","volume":"8","author":[{"given":"Anping","family":"Xia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yohan","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosalie","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon S.","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Will","family":"Clifton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Raphael","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung-il","family":"Chao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fred A.","family":"Pereira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew K.","family":"Groves","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John S.","family":"Oghalai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2013,12,20]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1038\/35012009","article-title":"Prestin is the motor protein of cochlear outer hair cells","volume":"405","author":"J Zheng","year":"2000","journal-title":"Nature"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1038\/nature01059","article-title":"Prestin is required for electromotility of the outer hair cell and for the cochlear amplifier","volume":"419","author":"MC Liberman","year":"2002","journal-title":"Nature"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/j.neuron.2008.02.028","article-title":"Prestin-based outer hair cell motility is necessary for mammalian cochlear amplification","volume":"58","author":"P Dallos","year":"2008","journal-title":"Neuron"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1007\/s10162-009-0196-5","article-title":"Glycosylation regulates prestin cellular activity","volume":"11","author":"L Rajagopalan","year":"2010","journal-title":"J Assoc Res Otolaryngol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"36659","DOI":"10.1074\/jbc.M705078200","article-title":"Tuning of the outer hair cell motor by membrane cholesterol","volume":"282","author":"L Rajagopalan","year":"2007","journal-title":"J Biol Chem"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"22473","DOI":"10.1074\/jbc.M803722200","article-title":"Membrane composition modulates prestin-associated charge movement","volume":"283","author":"J Sfondouris","year":"2008","journal-title":"J Biol Chem"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"2340","DOI":"10.1126\/science.1060939","article-title":"Intracellular anions as the voltage sensor of prestin, the outer hair cell motor protein","volume":"292","author":"D Oliver","year":"2001","journal-title":"Science"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"7693","DOI":"10.1073\/pnas.0608583104","article-title":"Nonmammalian orthologs of prestin (SLC26A5) are electrogenic divalent\/chloride anion exchangers","volume":"104","author":"TJ Schaechinger","year":"2007","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"3992","DOI":"10.1523\/JNEUROSCI.4548-05.2006","article-title":"Control of mammalian cochlear amplification by chloride anions","volume":"26","author":"J Santos-Sacchi","year":"2006","journal-title":"J Neurosci"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"12000","DOI":"10.1523\/JNEUROSCI.1651-09.2009","article-title":"A chimera analysis of prestin knock-out mice","volume":"29","author":"MA Cheatham","year":"2009","journal-title":"J Neurosci"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"e45453","DOI":"10.1371\/journal.pone.0045453","article-title":"Normal hearing sensitivity at low-to-middle frequencies with 34% prestin-charge density","volume":"7","author":"T Yamashita","year":"2012","journal-title":"PLoS One"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1242\/dmm.004135","article-title":"Deficient forward transduction and enhanced reverse transduction in the alpha tectorin C1509G human hearing loss mutation","volume":"3","author":"A Xia","year":"2010","journal-title":"Dis Model Mech"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"2530","DOI":"10.1016\/j.bpj.2011.04.024","article-title":"Structural and mechanical analysis of tectorial membrane Tecta mutants","volume":"100","author":"R Gueta","year":"2011","journal-title":"Biophys J"},{"key":"ref14","doi-asserted-by":"crossref","unstructured":"Liu CC, Gao SS, Yuan T, Steele C, Puria S, <etal>et al<\/etal>.. (2011) Biophysical Mechanisms Underlying Outer Hair Cell Loss Associated with a Shortened Tectorial Membrane. JARO-Journal of the Association for Research in Otolaryngology: 1\u201318.","DOI":"10.1007\/s10162-011-0269-0"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1007\/s10162-008-0116-0","article-title":"Characterization of a spontaneous, recessive, missense mutation arising in the Tecta gene","volume":"9","author":"MA Moreno-Pelayo","year":"2008","journal-title":"J Assoc Res Otolaryngol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"8791","DOI":"10.1074\/jbc.272.13.8791","article-title":"The mouse tectorins. Modular matrix proteins of the inner ear homologous to components of the sperm-egg adhesion system","volume":"272","author":"PK Legan","year":"1997","journal-title":"J Biol Chem"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1007\/s10162-010-0228-1","article-title":"Divergent aging characteristics in CBA\/J and CBA\/CaJ mouse cochleae","volume":"11","author":"KK Ohlemiller","year":"2010","journal-title":"J Assoc Res Otolaryngol"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/S0378-5955(99)00003-9","article-title":"Assessment of hearing in 80 inbred strains of mice by ABR threshold analyses","volume":"130","author":"QY Zheng","year":"1999","journal-title":"Hear Res"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1007\/s10162-011-0269-0","article-title":"Biophysical mechanisms underlying outer hair cell loss associated with a shortened tectorial membrane","volume":"12","author":"CC Liu","year":"2011","journal-title":"J Assoc Res Otolaryngol"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1007\/s10162-007-0092-9","article-title":"Altered traveling wave propagation and reduced endocochlear potential associated with cochlear dysplasia in the BETA2\/NeuroD1 null mouse","volume":"8","author":"A Xia","year":"2007","journal-title":"J Assoc Res Otolaryngol"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1529\/biophysj.103.033993","article-title":"Determination of cell capacitance using the exact empirical solution of partial differential Y\/partial differential Cm and its phase angle","volume":"87","author":"J Santos-Sacchi","year":"2004","journal-title":"Biophys J"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1111\/j.1469-7793.1999.0791n.x","article-title":"Expression density and functional characteristics of the outer hair cell motor protein are regulated during postnatal development in rat","volume":"3","author":"D Oliver","year":"1999","journal-title":"The Journal of physiology 519 Pt"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1007\/s00232-007-9004-5","article-title":"Developmental expression of the outer hair cell motor prestin in the mouse","volume":"215","author":"T Abe","year":"2007","journal-title":"J Membr Biol"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1364\/BOE.4.000230","article-title":"In vivo vibrometry inside the apex of the mouse cochlea using spectral domain optical coherence tomography","volume":"4","author":"SS Gao","year":"2013","journal-title":"Biomed Opt Express"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1152\/jn.00983.2007","article-title":"Development of cochlear amplification, frequency tuning, and two-tone suppression in the mouse","volume":"99","author":"L Song","year":"2008","journal-title":"J Neurophysiol"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1113\/jphysiol.2004.069559","article-title":"Cochlear function in Prestin knockout mice","volume":"560","author":"MA Cheatham","year":"2004","journal-title":"J Physiol"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.heares.2004.04.016","article-title":"The guide to plotting a cochleogram","volume":"197","author":"A Viberg","year":"2004","journal-title":"Hear Res"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"016002","DOI":"10.1117\/1.3290799","article-title":"Calcium imaging of inner ear hair cells within the cochlear epithelium of mice using two-photon microscopy","volume":"15","author":"T Yuan","year":"2010","journal-title":"Journal of Biomedical Optics"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1038\/nprot.2008.73","article-title":"Analyzing real-time PCR data by the comparative CT method","volume":"3","author":"TD Schmittgen","year":"2008","journal-title":"Nature protocols"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1007\/s101620020028","article-title":"Dynamics of noise-induced cellular injury and repair in the mouse cochlea","volume":"3","author":"Y Wang","year":"2002","journal-title":"J Assoc Res Otolaryngol"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1038\/322368a0","article-title":"Ionic basis of membrane potential in outer hair cells of guinea pig cochlea","volume":"322","author":"JF Ashmore","year":"1986","journal-title":"Nature"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"3096","DOI":"10.1523\/JNEUROSCI.11-10-03096.1991","article-title":"Reversible inhibition of voltage-dependent outer hair cell motility and capacitance","volume":"11","author":"J Santos-Sacchi","year":"1991","journal-title":"J Neurosci"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1002\/cne.21114","article-title":"Differential expression of unconventional myosins in apoptotic and regenerating chick hair cells confirms two regeneration mechanisms","volume":"499","author":"LJ Duncan","year":"2006","journal-title":"The Journal of comparative neurology"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1097\/01.moo.0000134449.05454.82","article-title":"The cochlear amplifier: augmentation of the traveling wave within the inner ear","volume":"12","author":"JS Oghalai","year":"2004","journal-title":"Curr Opin Otolaryngol Head Neck Surg"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1121\/1.380903","article-title":"Compound action potential (AP) tuning curves","volume":"59","author":"P Dallos","year":"1976","journal-title":"J Acoust Soc Am"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"14077","DOI":"10.1523\/JNEUROSCI.2845-09.2009","article-title":"Adding insult to injury: cochlear nerve degeneration after \u201ctemporary\u201d noise-induced hearing loss","volume":"29","author":"SG Kujawa","year":"2009","journal-title":"J Neurosci"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.heares.2006.08.011","article-title":"Prestin gene expression in the rat cochlea following intense noise exposure","volume":"222","author":"GD Chen","year":"2006","journal-title":"Hearing research"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.heares.2007.05.008","article-title":"Up-regulation of prestin mRNA expression in the organs of Corti of guinea pigs and rats following unilateral impulse noise exposure","volume":"231","author":"B Mazurek","year":"2007","journal-title":"Hear Res"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"2407","DOI":"10.1007\/s00018-008-8195-y","article-title":"Prestin up-regulation in chronic salicylate (aspirin) administration: an implication of functional dependence of prestin expression","volume":"65","author":"N Yu","year":"2008","journal-title":"Cellular and Molecular Life Sciences"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/S0896-6273(00)80756-4","article-title":"Role of alpha9 nicotinic ACh receptor subunits in the development and function of cochlear efferent innervation","volume":"23","author":"DE Vetter","year":"1999","journal-title":"Neuron"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"10838","DOI":"10.1523\/JNEUROSCI.22-24-10838.2002","article-title":"Efferent protection from acoustic injury is mediated via alpha9 nicotinic acetylcholine receptors on outer hair cells","volume":"22","author":"SF Maison","year":"2002","journal-title":"J Neurosci"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.devbrainres.2003.10.003","article-title":"Mouse outer hair cells lacking the alpha9 ACh receptor are motile","volume":"148","author":"DZ He","year":"2004","journal-title":"Brain Res Dev Brain Res"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"4241","DOI":"10.1523\/JNEUROSCI.22-10-04241.2002","article-title":"Variation in inter-animal susceptibility to noise damage is associated with alpha 9 acetylcholine receptor subunit expression level","volume":"22","author":"AE Luebke","year":"2002","journal-title":"J Neurosci"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1098\/rspb.1991.0065","article-title":"Direct measurement of the action of acetylcholine on isolated outer hair cells of the guinea pig cochlea","volume":"244","author":"GD Housley","year":"1991","journal-title":"Proceedings Biological sciences\/The Royal Society"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1121\/1.1912234","article-title":"Effects of electric stimulation of the crossed olivocochlear bundle on single auditory-nerve fibers in the cat","volume":"48","author":"ML Wiederhold","year":"1970","journal-title":"J Acoust Soc Am"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1126\/science.6623058","article-title":"Intracellular recordings from cochlear inner hair cells: effects of stimulation of the crossed olivocochlear efferents","volume":"222","author":"MC Brown","year":"1983","journal-title":"Science"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/0378-5955(82)90052-1","article-title":"Efferent neural control of cochlear mechanics? Olivocochlear bundle stimulation affects cochlear biomechanical nonlinearity","volume":"6","author":"JH Siegel","year":"1982","journal-title":"Hear Res"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1152\/physrev.1993.73.2.309","article-title":"Neurotransmitters and neuromodulators of the mammalian cochlea","volume":"73","author":"M Eybalin","year":"1993","journal-title":"Physiol Rev"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"e9058","DOI":"10.1371\/journal.pone.0009058","article-title":"Lack of nAChR activity depresses cochlear maturation and up-regulates GABA system components: temporal profiling of gene expression in alpha9 null mice","volume":"5","author":"S Turcan","year":"2010","journal-title":"PLoS One"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"3269","DOI":"10.1152\/jn.00067.2007","article-title":"A novel effect of cochlear efferents: in vivo response enhancement does not require alpha9 cholinergic receptors","volume":"97","author":"SF Maison","year":"2007","journal-title":"J Neurophysiol"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"2901","DOI":"10.1073\/pnas.052609899","article-title":"Thyroid hormone is a critical determinant for the regulation of the cochlear motor protein prestin","volume":"99","author":"T Weber","year":"2002","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref52","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1002\/dneu.20881","article-title":"Effects of retinoic acid and butyric acid on the expression of prestin and Gata-3 in organotypic cultures of the organ of corti of newborn rats","volume":"71","author":"J Gross","year":"2011","journal-title":"Dev Neurobiol"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1007\/s10571-011-9708-z","article-title":"Expression analysis of prestin and selected transcription factors in newborn rats","volume":"31","author":"J Gross","year":"2011","journal-title":"Cell Mol Neurobiol"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"R682","DOI":"10.1016\/j.cub.2011.08.001","article-title":"Prestin links extrinsic tuning to neural excitation in the mammalian cochlea","volume":"21","author":"TD Weddell","year":"2011","journal-title":"Curr Biol"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1007\/s10162-007-0092-9","article-title":"Altered traveling wave propagation and reduced endocochlear potential associated with cochlear dysplasia in the BETA2\/NeuroD1 null mouse","volume":"8","author":"A Xia","year":"2007","journal-title":"JARO-Journal of the Association for Research in Otolaryngology"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1002\/dneu.20357","article-title":"Prestin\u2013prestin and prestin\u2013GLUT5 interactions in HEK293T cells","volume":"67","author":"X Wu","year":"2007","journal-title":"Developmental neurobiology"},{"key":"ref57","doi-asserted-by":"crossref","unstructured":"Abe T, Kakehata S, Kitani R, Maruya SI, Navaratnam D, <etal>et al<\/etal>.. (2007) Developmental Expression of the Outer Hair Cell Motor Prestin in the Mouse. J Membr Biol.","DOI":"10.1007\/s00232-007-9004-5"},{"key":"ref58","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1113\/jphysiol.2005.093518","article-title":"Cochlear function in mice with only one copy of the prestin gene","volume":"569","author":"MA Cheatham","year":"2005","journal-title":"The Journal of physiology"},{"key":"ref59","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1007\/s004240050395","article-title":"The outer hair cell motor in membrane patches","volume":"434","author":"JE Gale","year":"1997","journal-title":"Pflugers Archiv: European journal of physiology"},{"key":"ref60","doi-asserted-by":"crossref","first-page":"2228","DOI":"10.1016\/S0006-3495(93)81248-7","article-title":"Mapping the distribution of the outer hair cell motility voltage sensor by electrical amputation","volume":"65","author":"G Huang","year":"1993","journal-title":"Biophys J"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1007\/BF00340870","article-title":"Structural features of the lateral walls in mammalian cochlear outer hair cells","volume":"265","author":"A Forge","year":"1991","journal-title":"Cell and tissue research"},{"key":"ref62","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1007\/s00424-002-0804-2","article-title":"Voltage-dependent changes in specific membrane capacitance caused by prestin, the outer hair cell lateral membrane motor","volume":"444","author":"J Santos-Sacchi","year":"2002","journal-title":"Pfl\u00fcgers Archiv European Journal of Physiology"},{"key":"ref63","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1113\/jphysiol.2006.114975","article-title":"Regulation of electromotility in the cochlear outer hair cell","volume":"576","author":"GI Frolenkov","year":"2006","journal-title":"The Journal of physiology"},{"key":"ref64","doi-asserted-by":"crossref","first-page":"8996","DOI":"10.1523\/JNEUROSCI.20-24-08996.2000","article-title":"Water permeability of cochlear outer hair cells: characterization and relationship to electromotility","volume":"20","author":"IA Belyantseva","year":"2000","journal-title":"J Neurosci"},{"key":"ref65","doi-asserted-by":"crossref","first-page":"2190","DOI":"10.1016\/S0006-3495(95)80401-7","article-title":"Membrane tension directly shifts voltage dependence of outer hair cell motility and associated gating charge","volume":"68","author":"S Kakehata","year":"1995","journal-title":"Biophysical Journal"},{"key":"ref66","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1007\/s002329900453","article-title":"Effects of lipophilic ions on outer hair cell membrane capacitance and motility","volume":"166","author":"M Wu","year":"1998","journal-title":"J Membr Biol"},{"key":"ref67","doi-asserted-by":"crossref","first-page":"e7923","DOI":"10.1371\/journal.pone.0007923","article-title":"Modulation of outer hair cell electromotility by cochlear supporting cells and gap junctions","volume":"4","author":"N Yu","year":"2009","journal-title":"PLoS ONE"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0082602","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,8]],"date-time":"2020-05-08T20:48:04Z","timestamp":1588970884000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0082602"}},"subtitle":[],"editor":[{"given":"Li I.","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2013,12,20]]},"references-count":67,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2013,12,20]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0082602","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,12,20]]}}}