{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T01:49:06Z","timestamp":1790732946833,"version":"4.1.0"},"reference-count":29,"publisher":"Public Library of Science (PLoS)","issue":"12","license":[{"start":{"date-parts":[[2013,12,19]],"date-time":"2013-12-19T00:00:00Z","timestamp":1387411200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0083892","type":"journal-article","created":{"date-parts":[[2013,12,19]],"date-time":"2013-12-19T17:08:17Z","timestamp":1387472897000},"page":"e83892","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":63,"title":["Hepatitis C Virus Co-Infection Increases the Risk of Anti-Tuberculosis Drug-Induced Hepatotoxicity among Patients with Pulmonary Tuberculosis"],"prefix":"10.1371","volume":"8","author":[{"given":"Nino","family":"Lomtadze","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lali","family":"Kupreishvili","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Archil","family":"Salakaia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergo","family":"Vashakidze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lali","family":"Sharvadze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Russell R.","family":"Kempker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew J.","family":"Magee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"del Rio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry M.","family":"Blumberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2013,12,19]]},"reference":[{"key":"ref1","year":"2013"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1016\/S0140-6736(03)14333-4","article-title":"Tuberculosis","volume":"362","author":"TR Frieden","year":"2003","journal-title":"Lancet"},{"key":"ref3","first-page":"164","article-title":"Risk for tuberculosis infection among internally displaced persons in the Republic of Georgia","volume":"5","author":"DM Weinstock","year":"2001","journal-title":"Int J Tuberc Lung Dis"},{"key":"ref4","first-page":"68","article-title":"Prevalence and risk factors for multidrug-resistant tuberculosis in the Republic of Georgia: a population-based study","volume":"13","author":"N Lomtadze","year":"2009","journal-title":"Int J Tuberc Lung Dis"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/S0140-6736(10)62173-3","article-title":"Tuberculosis","volume":"378","author":"SD Lawn","year":"2011","journal-title":"Lancet"},{"key":"ref6","article-title":"Multidrug and extensively drug-resistant TB (M\/XDR-TB): 2010 global report on surveillance and response","year":"2010"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1046\/j.1365-2893.1999.6120139.x","article-title":"Global surveillance and control of hepatitis C: Report of a WHO Consultation organized in collaboration with the Viral Hepatitis Prevention Board, Antwerp, Belgium","volume":"6","year":"1999","journal-title":"J Viral Hepat"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1016\/S1473-3099(05)70216-4","article-title":"Global epidemiology of hepatitis C virus infection","volume":"5","author":"CW Shepard","year":"2005","journal-title":"Lancet Infect Dis"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1023\/B:EJEP.0000032352.29173.78","article-title":"Risk Factors for Hepatitis C Virus Infection among Blood Donors in Georgia","volume":"19","author":"N Zaller","year":"2004","journal-title":"Eur J Epidemiol"},{"key":"ref10","first-page":"396","article-title":"High prevalence of hepatitis C virus but not HIV co-infection among patients with tuberculosis in Georgia","volume":"10","author":"DC Richards","year":"2006","journal-title":"International Journal of Tuberculosis and Lung Disease"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1023\/A:1015566132757","article-title":"Prevalence of hepatitis B, hepatitis C, syphilis and HIV in Georgian blood donors","volume":"17","author":"M Butsashvili","year":"2001","journal-title":"Eur J Epidemiol"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"1871","DOI":"10.1164\/ajrccm.157.6.9711039","article-title":"Antituberculosis drug-induced hepatotoxicity. The role of hepatitis C virus and the human immunodeficiency virus","volume":"157","author":"JR Ungo","year":"1998","journal-title":"Am J Respir Crit Care Med"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/j.jinf.2010.07.009","article-title":"Antituberculosis drug-induced liver injury in chronic hepatitis and cirrhosis","volume":"61","author":"WB Park","year":"2010","journal-title":"J Infect"},{"key":"ref14","article-title":"International Standards for Tuberculosis Care (ISTC)","year":"2009"},{"key":"ref15","article-title":"Treatment of tuberculosis guidelines","year":"2010"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1128\/CMR.00059-10","article-title":"Laboratory diagnosis of tuberculosis in resource-poor countries: challenges and opportunities","volume":"24","author":"LM Parsons","year":"2011","journal-title":"Clin Microbiol Rev"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"e31563","DOI":"10.1371\/journal.pone.0031563","article-title":"Use of a molecular diagnostic test in AFB smear positive tuberculosis suspects greatly reduces time to detection of multidrug resistant tuberculosis","volume":"7","author":"N Tukvadze","year":"2012","journal-title":"PLOS ONE"},{"key":"ref18","article-title":"Guidelines for surveillance of drug resistance in tuberculosis--4th edition","year":"2009"},{"key":"ref19","first-page":"51","article-title":"Prevailing HCV genotypes and subtypes among hiv infected patients in Georgia","author":"M Karchava","year":"2009","journal-title":"Georgian Med News"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"640","DOI":"10.7326\/0003-4819-137-8-200210150-00007","article-title":"Short-course rifampin and pyrazinamide compared with isoniazid for latent tuberculosis infection: a multicenter clinical trial","volume":"137","author":"RM Jasmer","year":"2002","journal-title":"Ann Intern Med"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1016\/j.jinf.2011.04.005","article-title":"Risk factors of hepatitis during anti-tuberculous treatment and implications of hepatitis virus load","volume":"62","author":"JY Wang","year":"2011","journal-title":"J Infect"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1378\/chest.06-2042","article-title":"Hepatitis C virus infection and hepatotoxicity during antituberculosis chemotherapy","volume":"131","author":"YS Kwon","year":"2007","journal-title":"Chest"},{"key":"ref23","first-page":"616","article-title":"Hepatitis C virus infection increases hepatitis risk during anti-tuberculosis treatment","volume":"14","author":"JY Chien","year":"2010","journal-title":"Int J Tuberc Lung Dis"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1056\/NEJM200107053450107","article-title":"Hepatitis C Virus","volume":"345","author":"GM Lauer","year":"2001","journal-title":"Infection - New England Journal of Medicine"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"S35","DOI":"10.1016\/S0376-8716(06)80006-2","article-title":"Risk behaviors and HIV, hepatitis B, and hepatitis C seroprevalence among injection drug users in Georgia","volume":"82","author":"E NK Shapatava","year":"2006","journal-title":"Drug Alcohol Depend"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"e928","DOI":"10.1016\/j.ijid.2010.03.019","article-title":"Tattooing and the risk of transmission of hepatitis C: a systematic review and meta-analysis","volume":"14","author":"S Jafari","year":"2010","journal-title":"Int J Infect Dis"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1111\/j.1440-1746.2007.05207.x","article-title":"Antituberculosis drug-induced hepatotoxicity: concise up-to-date review","volume":"23","author":"A Tostmann","year":"2008","journal-title":"J Gastroenterol Hepatol"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"1472","DOI":"10.1164\/rccm.200206-626OC","article-title":"Incidence of serious side effects from first-line antituberculosis drugs among patients treated for active tuberculosis","volume":"167","author":"D Yee","year":"2003","journal-title":"Am J Respir Crit Care Med"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1164\/rccm.167.4.603","article-title":"American Thoracic Society\/Centers for Disease Control and Prevention\/Infectious Diseases Society of America: treatment of tuberculosis","volume":"167","author":"HM Blumberg","year":"2003","journal-title":"Am J Respir Crit Care Med"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0083892","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,10,23]],"date-time":"2018-10-23T03:57:26Z","timestamp":1540267046000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0083892"}},"subtitle":[],"editor":[{"given":"Wenzhe","family":"Ho","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2013,12,19]]},"references-count":29,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2013,12,19]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0083892","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,12,19]]}}}