{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T10:43:43Z","timestamp":1761561823442},"reference-count":38,"publisher":"Public Library of Science (PLoS)","issue":"12","license":[{"start":{"date-parts":[[2013,12,11]],"date-time":"2013-12-11T00:00:00Z","timestamp":1386720000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0083936","type":"journal-article","created":{"date-parts":[[2013,12,11]],"date-time":"2013-12-11T21:40:05Z","timestamp":1386798005000},"page":"e83936","update-policy":"http:\/\/dx.doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":9,"title":["Linkage Analysis in Familial Non-Lynch Syndrome Colorectal Cancer Families from Sweden"],"prefix":"10.1371","volume":"8","author":[{"given":"Vinaykumar","family":"Kontham","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susanna","family":"von Holst","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annika","family":"Lindblom","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2013,12,11]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1023\/A:1025734200635","article-title":"Family history of colorectal cancer in a Sweden county","volume":"2","author":"L Olsson","year":"2003","journal-title":"Fam Cancer"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1399-0004.2009.01230.x","article-title":"Review of the Lynch syndrome: history, molecular genetics, screening, differential diagnosis, and medicolegal ramifications","volume":"76","author":"HT Lynch","year":"2009","journal-title":"Clin Genet"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1038\/sj.bjc.6603997","article-title":"National study of colorectal cancer genetics","volume":"97","author":"S Penegar","year":"2007","journal-title":"Br J Cancer"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"1979","DOI":"10.1001\/jama.293.16.1979","article-title":"Lower cancer incidence in Amsterdam-I criteria families without mismatch repair deficiency - Familial colorectal cancer type X","volume":"293","author":"NM Lindor","year":"2005","journal-title":"JAMA:_Journal of the American Medical Association"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1038\/ng2089","article-title":"Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24","volume":"39","author":"BW Zanke","year":"2007","journal-title":"Nat Genet"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1038\/ng.111","article-title":"A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3","volume":"40","author":"IP Tomlinson","year":"2008","journal-title":"Nat Genet"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1038\/ng2085","article-title":"A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21","volume":"39","author":"I Tomlinson","year":"2007","journal-title":"Nat Genet"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1038\/ng.133","article-title":"Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21","volume":"40","author":"A Tenesa","year":"2008","journal-title":"Nat Genet"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1038\/ng.2007.41","article-title":"Common genetic variants at the CRAC1 (HMPS) locus on chromosome 15q13.3 influence colorectal cancer risk","volume":"40","author":"E Jaeger","year":"2008","journal-title":"Nat Genet"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.1038\/ng.262","article-title":"Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer","volume":"40","author":"RS Houlston","year":"2008","journal-title":"Nat Genet"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1038\/ng.670","article-title":"Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33","volume":"42","author":"RS Houlston","year":"2010","journal-title":"Nat Genet"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1038\/ng2098","article-title":"A common genetic risk factor for colorectal and prostate cancer","volume":"39","author":"CA Haiman","year":"2007","journal-title":"Nat Genet"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1038\/ng.2007.18","article-title":"A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk","volume":"39","author":"P Broderick","year":"2007","journal-title":"Nat Genet"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1038\/ng.2293","article-title":"Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk","volume":"44","author":"MG Dunlop","year":"2012","journal-title":"Nat Genet"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1038\/328614a0","article-title":"Localization of the gene for familial adenomatous polyposis on chromosome 5","volume":"328","author":"WF Bodmer","year":"1987","journal-title":"Nature"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1126\/science.8484120","article-title":"Genetic mapping of a locus predisposing to human colorectal cancer","volume":"260","author":"P Peltom\u00e4ki","year":"1993","journal-title":"Science"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1038\/ng1193-279","article-title":"Genetic mapping of a second locus predisposing to hereditary non-polyposis colon cancer","volume":"5","author":"A Lindblom","year":"1993","journal-title":"Nat Genet"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"5003","DOI":"10.1158\/0008-5472.CAN-05-4074","article-title":"Evidence of linkage to chromosome 9q22.33 in colorectal cancer kindreds from the United Kingdom","volume":"66","author":"ZE Kemp","year":"2006","journal-title":"Cancer Res"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"e7","DOI":"10.1136\/jmg.2005.033928","article-title":"Linkage analysis in a large Swedish family supports the presence of a susceptibility locus for adenoma and colorectal cancer on chromosome 9q22.32-31.1","volume":"43","author":"J Skoglund","year":"2006","journal-title":"J Med Genet"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"12961","DOI":"10.1073\/pnas.2132286100","article-title":"A subset of familial colorectal neoplasia kindreds linked to chromosome 9q22.2-31.2","volume":"100","author":"GL Wiesner","year":"2003","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"2903","DOI":"10.1093\/hmg\/ddl231","article-title":"Evidence for a colorectal cancer susceptibility locus on chromosome 3q21-q24 from a high-density SNP genome-wide linkage scan","volume":"15","author":"Z Kemp","year":"2006","journal-title":"Hum Mol Genet"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1186\/1471-2407-8-87","article-title":"Genome-wide linkage scan for colorectal cancer susceptibility genes supports linkage to chromosome 3q","volume":"8","author":"S Picelli","year":"2008","journal-title":"BMC Cancer"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1136\/gut.2005.075333","article-title":"A genome wide linkage analysis in Swedish families with hereditary non-familial adenomatous polyposis\/non-hereditary non-polyposis colorectal cancer","volume":"55","author":"T Djureinovic","year":"2006","journal-title":"Gut"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1038\/ejhg.2011.149","article-title":"Evidence of linkage to chromosomes 10p15.3-p15.1, 14q24.3-q31.1 and 9q33.3-q34.3 in non-syndromic colorectal cancer families","volume":"20","author":"IW Saunders","year":"2012","journal-title":"Eur J Hum Genet"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1007\/s10689-010-9408-8","article-title":"Linkage to chromosome 2q32.2-q33.3 in familial serrated neoplasia (Jass syndrome)","volume":"10","author":"A Roberts","year":"2011","journal-title":"Fam Cancer"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"e38175","DOI":"10.1371\/journal.pone.0038175","article-title":"Colorectal cancer linkage on chromosomes 4q21, 8q13, 12q24, and 15q22","volume":"7","author":"MS Cicek","year":"2012","journal-title":"PLOS ONE"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1093\/jnci\/djk051","article-title":"Lynch syndrome (hereditary nonpolyposis colorectal cancer) diagnostics","volume":"99","author":"K Lagerstedt Robinson","year":"2007","journal-title":"J Natl Cancer Inst"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1038\/ng1547","article-title":"A genome-wide scalable SNP genotyping assay using microarray technology","volume":"37","author":"KL Gunderson","year":"2005","journal-title":"Nat Genet"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1038\/nmeth842","article-title":"Whole-genome genotyping with the single-base extension assay","volume":"3","author":"FJ Steemers","year":"2006","journal-title":"Nat Methods"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1101\/sqb.2003.68.69","article-title":"Highly parallel SNP genotyping","volume":"68","author":"JB Fan","year":"2003","journal-title":"Cold Spring Harb Symp Quant Biol"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1086\/301904","article-title":"PedCheck: A program for identification of genotype incompatibilities in linkage analysis","volume":"63","author":"JR O'Connell","year":"1998","journal-title":"Am J Hum Genet"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"118","DOI":"10.2307\/2533202","article-title":"A Class of Tests for Linkage Using Affected Pedigree Members","volume":"50","author":"AS Whittemore","year":"1994","journal-title":"Biometrics"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1038\/ng786","article-title":"Merlin-rapid analysis of dense genetic maps using sparse gene flow trees","volume":"30","author":"GR Abecasis","year":"2002","journal-title":"Nat Genet"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"S82","DOI":"10.1186\/1471-2156-6-S1-S82","article-title":"Bias of allele-sharing linkage statistics in the presence of intermarker linkage disequilibrium","volume":"6","author":"EL Goode","year":"2005","journal-title":"BMC Genet"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1002\/gcc.20763","article-title":"Comprehensive genetic analysis of seven large families with mismatch repair proficient colorectal cancer","volume":"49","author":"A Middeldorp","year":"2010","journal-title":"Genes Chromosomes Cancer"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"5409","DOI":"10.1158\/0008-5472.CAN-10-0188","article-title":"Confirmation of linkage to and localization of familial colon cancer risk haplotype on chromosome 9q22","volume":"70","author":"C Gray-McGuire","year":"2010","journal-title":"Cancer Res"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1126\/science.1159397","article-title":"Germline allele-specific expression of TGFBR1 confers an increased risk of colorectal cancer","volume":"321","author":"L Valle","year":"2008","journal-title":"Science"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"12921","DOI":"10.1073\/pnas.0901454106","article-title":"Inactivating germ-line and somatic mutations in polypeptide N-acetylgalactosaminyltransferase 12 in human colon cancers","volume":"106","author":"K Guda","year":"2009","journal-title":"Proc Natl Acad Sci U S A"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0083936","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,21]],"date-time":"2024-05-21T11:05:02Z","timestamp":1716289502000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0083936"}},"subtitle":[],"editor":[{"given":"Nathan\u00a0A.","family":"Ellis","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2013,12,11]]},"references-count":38,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2013,12,11]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0083936","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,12,11]]}}}