{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T13:19:27Z","timestamp":1775308767247,"version":"3.50.1"},"reference-count":41,"publisher":"Public Library of Science (PLoS)","issue":"12","license":[{"start":{"date-parts":[[2013,12,31]],"date-time":"2013-12-31T00:00:00Z","timestamp":1388448000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0084207","type":"journal-article","created":{"date-parts":[[2013,12,31]],"date-time":"2013-12-31T22:13:00Z","timestamp":1388527980000},"page":"e84207","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":39,"title":["Association of Impulsivity and Polymorphic MicroRNA-641 Target Sites in the SNAP-25 Gene"],"prefix":"10.1371","volume":"8","author":[{"given":"N\u00f3ra","family":"N\u00e9meth","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R\u00e9ka","family":"Kov\u00e1cs-Nagy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Sz\u00e9kely","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00e1ria","family":"Sasv\u00e1ri-Sz\u00e9kely","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zsolt","family":"R\u00f3nai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2013,12,31]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1680","DOI":"10.1176\/appi.ajp.162.9.1680","article-title":"Increased impulsivity associated with severity of suicide attempt history in patients with bipolar disorder","volume":"162","author":"AC Swann","year":"2005","journal-title":"The American journal of psychiatry"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1111\/j.1467-6494.2008.00528.x","article-title":"A neurogenetic approach to impulsivity","volume":"76","author":"E Congdon","year":"2008","journal-title":"Journal of personality"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1089\/cap.2010.0096","article-title":"Impulsivity in adolescents with bipolar disorder and\/or attention-deficit\/hyperactivity disorder and healthy controls as measured by the Barratt Impulsiveness Scale","volume":"21","author":"JJ Nandagopal","year":"2011","journal-title":"Journal of child and adolescent psychopharmacology"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.pneurobio.2012.08.003","article-title":"The serotonin transporter gene and functional and pathological adaptation to environmental variation across the life span","volume":"99","author":"JR Homberg","year":"2012","journal-title":"Progress in neurobiology"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1016\/j.neubiorev.2011.04.002","article-title":"Psychopathological aspects of dopaminergic gene polymorphisms in adolescence and young adulthood","volume":"35","author":"Z Nemoda","year":"2011","journal-title":"Neuroscience and biobehavioral reviews"},{"key":"ref6","first-page":"93","article-title":"Candidate gene studies of dopaminergic and serotonergic polymorphisms","volume":"13","author":"G Varga","year":"2011","journal-title":"Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja \u200a=\u200a official journal of the Hungarian Association of Psychopharmacology"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/s00213-010-1915-7","article-title":"A functional NOS1 promoter polymorphism interacts with adverse environment on functional and dysfunctional impulsivity","volume":"214","author":"A Reif","year":"2011","journal-title":"Psychopharmacology"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1176\/appi.ajp.2011.10101446","article-title":"Nitric oxide synthase genotype modulation of impulsivity and ventral striatal activity in adult ADHD patients and healthy comparison subjects","volume":"168","author":"M Hoogman","year":"2011","journal-title":"The American journal of psychiatry"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"e31","DOI":"10.1016\/j.drugalcdep.2011.05.025","article-title":"Associations among types of impulsivity, substance use problems and neurexin-3 polymorphisms","volume":"119","author":"SF Stoltenberg","year":"2011","journal-title":"Drug and alcohol dependence"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.psc.2009.12.004","article-title":"Molecular genetics of attention deficit hyperactivity disorder","volume":"33","author":"SV Faraone","year":"2010","journal-title":"The Psychiatric clinics of North America"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1038\/sj.mp.4000733","article-title":"Identification of DNA variants in the SNAP-25 gene and linkage study of these polymorphisms and attention-deficit hyperactivity disorder","volume":"5","author":"CL Barr","year":"2000","journal-title":"Molecular psychiatry"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1002\/ajmg.b.30522","article-title":"Investigation of variation in SNAP-25 and ADHD and relationship to co-morbid major depressive disorder","volume":"144B","author":"JW Kim","year":"2007","journal-title":"American journal of medical genetics Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1038\/sj.mp.4001482","article-title":"Haplotype analysis of SNAP-25 suggests a role in the aetiology of ADHD","volume":"9","author":"J Mill","year":"2004","journal-title":"Molecular psychiatry"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1007\/s00439-009-0694-x","article-title":"Candidate gene studies of ADHD: a meta-analytic review","volume":"126","author":"IR Gizer","year":"2009","journal-title":"Human genetics"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1038\/mp.2008.148","article-title":"A SNAP25 promoter variant is associated with early-onset bipolar disorder and a high expression level in brain","volume":"15","author":"B Etain","year":"2010","journal-title":"Molecular psychiatry"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1002\/ajmg.b.30915","article-title":"Evidence that putative ADHD low risk alleles at SNAP25 may increase the risk of schizophrenia","volume":"150B","author":"LS Carroll","year":"2009","journal-title":"American journal of medical genetics Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1111\/j.1399-5618.2006.00300.x","article-title":"Increased levels of SNAP-25 and synaptophysin in the dorsolateral prefrontal cortex in bipolar I disorder","volume":"8","author":"E Scarr","year":"2006","journal-title":"Bipolar disorders"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.neuroscience.2008.03.014","article-title":"The Synaptic Split of Snap-25: Different Roles in Glutamatergic and Gabaergic Neurons?","volume":"158","author":"M Matteoli","year":"2009","journal-title":"Neuroscience"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"2013","DOI":"10.1002\/elps.201000536","article-title":"Haplotyping of putative microRNA-binding sites in the SNAP-25 gene","volume":"32","author":"R Kovacs-Nagy","year":"2011","journal-title":"Electrophoresis"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1002\/humu.21641","article-title":"Genome-wide identification of SNPs in microRNA genes and the SNP effects on microRNA target binding and biogenesis","volume":"33","author":"J Gong","year":"2012","journal-title":"Human mutation"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.schres.2012.06.038","article-title":"Experimental validation of candidate schizophrenia gene ZNF804A as target for hsa-miR-137","volume":"141","author":"AH Kim","year":"2012","journal-title":"Schizophrenia research"},{"key":"ref22","doi-asserted-by":"crossref","unstructured":"Wu C, Gong Y, Sun A, Zhang Y, Zhang C, <etal>et al<\/etal>.. (2012) The human MTHFR rs4846049 polymorphism increases coronary heart disease risk through modifying miRNA binding. Nutrition, metabolism, and cardiovascular diseases : NMCD.","DOI":"10.1016\/j.numecd.2012.02.009"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.ygeno.2011.06.005","article-title":"C-T variant in a miRNA target site of BCL2 is associated with increased risk of human papilloma virus related cervical cancer\u2014an in silico approach","volume":"98","author":"G Reshmi","year":"2011","journal-title":"Genomics"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"5175","DOI":"10.1158\/0008-5472.CAN-10-4407","article-title":"Genetic variation in an miRNA-1827 binding site in MYCL1 alters susceptibility to small-cell lung cancer","volume":"71","author":"F Xiong","year":"2011","journal-title":"Cancer research"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1038\/sj.mp.4001092","article-title":"Synaptosomal-associated protein 25 (SNAP-25) and attention deficit hyperactivity disorder (ADHD): evidence of linkage and association in the Irish population","volume":"7","author":"K Brophy","year":"2002","journal-title":"Molecular psychiatry"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1038\/mp.2008.15","article-title":"A common polymorphism in serotonin receptor 1B mRNA moderates regulation by miR-96 and associates with aggressive human behaviors","volume":"14","author":"KP Jensen","year":"2009","journal-title":"Molecular psychiatry"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1002\/1097-4679(199511)51:6<768::AID-JCLP2270510607>3.0.CO;2-1","article-title":"Factor structure of the Barratt impulsiveness scale","volume":"51","author":"JH Patton","year":"1995","journal-title":"Journal of clinical psychology"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1086\/319501","article-title":"A new statistical method for haplotype reconstruction from population data","volume":"68","author":"M Stephens","year":"2001","journal-title":"American journal of human genetics"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"205","DOI":"10.5507\/bp.2006.029","article-title":"MicroRNA biogenesis, functionality and cancer relevance","volume":"150","author":"B Kusenda","year":"2006","journal-title":"Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"D216","DOI":"10.1093\/nar\/gkr1026","article-title":"PolymiRTS Database 2.0: linking polymorphisms in microRNA target sites with human diseases and complex traits","volume":"40","author":"JD Ziebarth","year":"2012","journal-title":"Nucleic acids research"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"1753","DOI":"10.1261\/rna.2248605","article-title":"MicroRNA function: multiple mechanisms for a tiny RNA?","volume":"11","author":"RS Pillai","year":"2005","journal-title":"RNA"},{"key":"ref32","doi-asserted-by":"crossref","unstructured":"Takada S, Asahara H (2012) Current strategies for microRNA research. Modern rheumatology\/the Japan Rheumatism Association.","DOI":"10.3109\/s10165-011-0583-8"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1016\/j.biocel.2010.03.003","article-title":"The road toward microRNA therapeutics","volume":"42","author":"AG Seto","year":"2010","journal-title":"The international journal of biochemistry & cell biology"},{"key":"ref34","first-page":"361","article-title":"Candidate genes involved in neural plasticity and the risk for attention-deficit hyperactivity disorder: a meta-analysis of 8 common variants","volume":"34","author":"DA Forero","year":"2009","journal-title":"Journal of psychiatry & neuroscience : JPN"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1007\/s11064-011-0618-8","article-title":"Role of SNAP25 explored in eastern Indian attention deficit hyperactivity disorder probands","volume":"37","author":"K Sarkar","year":"2012","journal-title":"Neurochemical research"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.ejpn.2010.06.001","article-title":"An association study between SNAP-25 gene and attention-deficit hyperactivity disorder","volume":"15","author":"H Zhang","year":"2011","journal-title":"European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.jneumeth.2006.12.005","article-title":"Neurobiology of animal models of attention-deficit hyperactivity disorder","volume":"161","author":"VA Russell","year":"2007","journal-title":"Journal of neuroscience methods"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.pnpbp.2012.08.012","article-title":"Altered gene expression in the prefrontal cortex of young rats induced by the ADHD drug atomoxetine","volume":"40","author":"T Lempp","year":"2013","journal-title":"Progress in neuro-psychopharmacology & biological psychiatry"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"e60274","DOI":"10.1371\/journal.pone.0060274","article-title":"DNA variation in the SNAP25 gene confers risk to ADHD and is associated with reduced expression in prefrontal cortex","volume":"8","author":"Z Hawi","year":"2013","journal-title":"PloS one"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/j.gene.2013.07.004","article-title":"The relationship between the presence of ADHD and certain candidate gene polymorphisms in a Turkish sample","volume":"528","author":"O Pazvantoglu","year":"2013","journal-title":"Gene"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1097\/00041444-200512000-00008","article-title":"Linkage analysis and molecular haplotyping of the dopamine D4 receptor gene promoter region","volume":"15","author":"E Szantai","year":"2005","journal-title":"Psychiatric genetics"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0084207","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,22]],"date-time":"2024-05-22T11:42:43Z","timestamp":1716378163000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0084207"}},"subtitle":[],"editor":[{"given":"Andreas","family":"Reif","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2013,12,31]]},"references-count":41,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2013,12,31]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0084207","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,12,31]]}}}