{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T16:47:00Z","timestamp":1790786820801,"version":"4.1.0"},"reference-count":41,"publisher":"Public Library of Science (PLoS)","issue":"12","license":[{"start":{"date-parts":[[2013,12,31]],"date-time":"2013-12-31T00:00:00Z","timestamp":1388448000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0085179","type":"journal-article","created":{"date-parts":[[2013,12,31]],"date-time":"2013-12-31T17:25:06Z","timestamp":1388510706000},"page":"e85179","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":80,"title":["The Role of Prostatitis in Prostate Cancer: Meta-Analysis"],"prefix":"10.1371","volume":"8","author":[{"given":"Junyi","family":"Jiang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinyi","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhang","family":"Yunxia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junjiang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"Pumill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2013,12,31]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/0027-5107(94)90245-3","article-title":"Chronic infections and inflammatory processes as cancer risk factors: possible role of nitric oxide in carcinogenesis","volume":"305","author":"H Ohshima","year":"1994","journal-title":"Mutat Res"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"G515","DOI":"10.1152\/ajpgi.00475.2003","article-title":"Inflammation and Cancer II. Role of chronic inflammation and cytokine gene polymorphisms in the pathogenesis of gastrointestinal malignancy","volume":"286","author":"M Macarthur","year":"2004","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"2101","DOI":"10.1053\/j.gastro.2010.01.058","article-title":"Inflammation and colon cancer","volume":"138","author":"J Terzic","year":"2010","journal-title":"Gastroenterology"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1016\/j.ejca.2006.01.020","article-title":"Helicobacter pylori infection and gastric cancer","volume":"42","author":"T Matysiak-Budnik","year":"2006","journal-title":"Eur J Cancer"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1159\/000337314","article-title":"Obesity, Diabetes, the Cardiorenal Syndrome, and Risk for Cancer","volume":"2","author":"V Forte","year":"2012","journal-title":"Cardiorenal Med"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1159\/000336991","article-title":"The role of chronic inflammation: chronic pancreatitis as a risk factor of pancreatic cancer","volume":"30","author":"P D\u00edt\u011b","year":"2012","journal-title":"Dig Dis"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"1999","DOI":"10.1002\/ijc.25815","article-title":"Reactive species and DNA damage in chronic inflammation: reconciling chemical mechanisms and biological fates","volume":"128","author":"P Lonkar","year":"2011","journal-title":"Int J Cancer"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1093\/carcin\/bgp272","article-title":"Inflammation and cancer: interweaving microRNA, free radical, cytokine and p53 pathways","volume":"31","author":"AJ Schetter","year":"2010","journal-title":"Carcinogenesis"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"359","DOI":"10.18632\/oncotarget.482","article-title":"Pro-malignant properties of STAT3 during chronic inflammation","volume":"3","author":"M Demaria","year":"2012","journal-title":"Oncotarget"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1038\/embor.2009.243","article-title":"IKK\/NF-kappaB and STAT3 pathways: central signalling hubs in inflammation-mediated tumour promotion and metastasis","volume":"10","author":"J Bollrath","year":"2009","journal-title":"EMBO Rep"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1097\/01.jom.0000071510.96740.0b","article-title":"Organochlorines and risk of prostate cancer","volume":"45","author":"JM Ritchie","year":"2003","journal-title":"J Occup Environ Med"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1038\/sj.pcan.4500604","article-title":"Management of prostatitis","volume":"5","author":"Rao Tunuguntla","year":"2002","journal-title":"Prostate Cancer Prostatic Dis"},{"key":"ref13","first-page":"397","article-title":"Prostatitis: diagnosis and treatment","volume":"82","author":"VJ Sharp","year":"2010","journal-title":"Am Fam Physician"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/1476-072X-5-8","article-title":"Effects of study area size on geographic characterizations of health events: prostate cancer incidence in Southern New England, USA, 1994-1998","volume":"5","author":"DI Gregorio","year":"2006","journal-title":"Int J Health Geogr"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1002\/ijc.23500","article-title":"Investigating Black-White differences in prostate cancer prognosis: A systematic review and meta-analysis","volume":"123","author":"S Evans","year":"2008","journal-title":"Int J Cancer"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1111\/j.1365-2605.2005.00560.x","article-title":"Epidemiologic risk factors for chronic prostatitis","volume":"28","author":"JH Ku","year":"2005","journal-title":"Int J Androl"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1158\/1541-7786.MCR-05-0261","article-title":"Inflammation, a key event in cancer development","volume":"4","author":"H Lu","year":"2006","journal-title":"Mol Cancer Res"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/S0090-4295(02)01637-0","article-title":"Epidemiologic association between prostatitis and prostate cancer","volume":"60","author":"LK Dennis","year":"2002","journal-title":"Urology"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/S0090-4295(99)00205-8","article-title":"Research guidelines for chronic prostatitis: consensus report from the First National Institutes of Health International Prostatitis Collaborative Network","volume":"54","author":"JC Nickel","year":"1999","journal-title":"Urology"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1097\/01.ede.0000101022.38330.7c","article-title":"Prostatitis as a risk factor for prostate cancer","volume":"15","author":"RO Roberts","year":"2004","journal-title":"Epidemiology"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.1016\/j.juro.2008.01.034","article-title":"Evaluation of prostatitis in autopsied prostates--is chronic inflammation more associated with benign prostatic hyperplasia or cancer?","volume":"179","author":"NB Delongchamps","year":"2008","journal-title":"J Urol"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1093\/aje\/153.12.1152","article-title":"Sexual factors and the risk of prostate cancer","volume":"153","author":"KA Rosenblatt","year":"2001","journal-title":"Am J Epidemiol"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1186\/1756-0500-2-57","article-title":"Antibiotic and anti-inflammatory use and the risk of prostate cancer","volume":"2","author":"NA Daniels","year":"2009","journal-title":"BMC Res Notes"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1007\/BF01830728","article-title":"Alcohol consumption, smoking, and other risk factors and prostate cancer in a large health plan cohort in California (United States)","volume":"5","author":"RA Hiatt","year":"1994","journal-title":"Cancer Causes Control"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1023\/A:1008840105531","article-title":"Case-control study of diet and prostate cancer in China","volume":"9","author":"MM Lee","year":"1998","journal-title":"Cancer Causes Control"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1093\/ije\/28.3.409","article-title":"Comparison of self-report data and medical records data: results from a case-control study on prostate cancer","volume":"28","author":"K Zhu","year":"1999","journal-title":"Int J Epidemiol"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1093\/ije\/dyh332","article-title":"Sexual behaviour, history of sexually transmitted diseases, and the risk of prostate cancer: a case-control study in Cuba","volume":"34","author":"L Fern\u00e1ndez","year":"2005","journal-title":"Int J Epidemiol"},{"key":"ref28","first-page":"285","article-title":"Vasectomy and prostate cancer risk in China","volume":"3","author":"AW Hsing","year":"1994","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1016\/j.juro.2006.04.075","article-title":"Sexual behavior, sexually transmitted diseases and prostatitis: the risk of prostate cancer in black men","volume":"176","author":"AV Sarma","year":"2006","journal-title":"J Urol"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1097\/01.cej.0000198897.40303.d4","article-title":"Genital and urinary tract diseases and prostate cancer risk","volume":"15","author":"C Pelucchi","year":"2006","journal-title":"Eur J Cancer Prev"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1007\/s10552-004-3486-6","article-title":"Sexually transmitted diseases and other urogenital conditions as risk factors for prostate cancer: a case--control study in Wayne County, Michigan","volume":"16","author":"DA Patel","year":"2005","journal-title":"Cancer Causes Control"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"1573","DOI":"10.1158\/1055-9965.EPI-07-0134","article-title":"Plasma antibodies against Chlamydia trachomatis, human papillomavirus, and human herpesvirus type 8 in relation to prostate cancer: a prospective study","volume":"16","author":"S Sutcliffe","year":"2007","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1016\/j.urology.2004.06.071","article-title":"Self-report of prostatitis and its risk factors in a random sample of middle-aged men","volume":"64","author":"I Rothman","year":"2004","journal-title":"Urology"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1007\/s10552-009-9441-9","article-title":"Medical history, body size, and cigarette smoking in relation to fatal prostate cancer","volume":"21","author":"S Weinmann","year":"2010","journal-title":"Cancer Causes Control"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"2374","DOI":"10.1158\/1055-9965.EPI-08-0173","article-title":"Sexually transmissible infections and prostate cancer risk","volume":"17","author":"WY Huang","year":"2008","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1093\/jnci\/87.9.662","article-title":"Vasectomy and prostate cancer: results from a multiethnic case-control study","volume":"87","author":"EM John","year":"1995","journal-title":"J Natl Cancer Inst"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"4437","DOI":"10.1002\/cncr.26653","article-title":"Circumcision and the risk of prostate cancer","volume":"118","author":"JL Wright","year":"2012","journal-title":"Cancer"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"2551","DOI":"10.1158\/1055-9965.EPI-11-0777","article-title":"HIV infection, immunodeficiency, viral replication, and the risk of cancer","volume":"20","author":"MJ Silverberg","year":"2011","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1002\/ijc.24637","article-title":"Red wine consumption and risk of prostate cancer: the California men's health study","volume":"126","author":"C Chao","year":"2010","journal-title":"Int J Cancer"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.amjopharm.2011.02.005","article-title":"Identification, pharmacologic considerations, and management of prostatitis","volume":"9","author":"DS Schiller","year":"2011","journal-title":"Am J Geriatr Pharmacother"},{"key":"ref41","first-page":"75","article-title":"Critical issues in chronic prostatitis","volume":"82","author":"V Magri","year":"2010","journal-title":"Arch Ital Urol Androl"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0085179","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,8]],"date-time":"2020-05-08T16:04:11Z","timestamp":1588953851000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0085179"}},"subtitle":[],"editor":[{"given":"Georgios","family":"Gakis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2013,12,31]]},"references-count":41,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2013,12,31]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0085179","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,12,31]]}}}