{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,15]],"date-time":"2026-02-15T21:15:49Z","timestamp":1771190149298,"version":"3.50.1"},"reference-count":25,"publisher":"Public Library of Science (PLoS)","issue":"1","license":[{"start":{"date-parts":[[2014,1,22]],"date-time":"2014-01-22T00:00:00Z","timestamp":1390348800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0085210","type":"journal-article","created":{"date-parts":[[2014,1,22]],"date-time":"2014-01-22T17:28:32Z","timestamp":1390411712000},"page":"e85210","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":20,"title":["Clinical Impact of Fluoroquinolone-Resistant Escherichia coli in the Fecal Flora of Hematological Patients with Neutropenia and Levofloxacin Prophylaxis"],"prefix":"10.1371","volume":"9","author":[{"given":"Yong","family":"Chong","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinji","family":"Shimoda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroko","family":"Yakushiji","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshikiyo","family":"Ito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takatoshi","family":"Aoki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshihiro","family":"Miyamoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomohiko","family":"Kamimura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuyuki","family":"Shimono","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koichi","family":"Akashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2014,1,22]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1097\/00001432-200208000-00004","article-title":"Treatment of febrile neutropenia: what is new?","volume":"15","author":"C Viscoli","year":"2002","journal-title":"Curr Opin Infect Dis"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1056\/NEJMoa044097","article-title":"Levofloxacin to prevent bacterial infection in patients with cancer and neutropenia","volume":"353","author":"G Bucaneve","year":"2005","journal-title":"N Engl J Med"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"979","DOI":"10.7326\/0003-4819-142-12_Part_1-200506210-00008","article-title":"Meta-analysis: antibiotic prophylaxis reduces mortality in neutropenic patients","volume":"142","author":"A Gafter-Gvili","year":"2005","journal-title":"Ann Intern Med"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"1743","DOI":"10.1002\/cncr.22205","article-title":"Antibiotic prophylaxis in neutropenic patients: new evidence, practical decisions","volume":"107","author":"L Leibovici","year":"2006","journal-title":"Cancer"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1097\/MOH.0b013e32831ac543","article-title":"Antibiotics for the prevention of febrile neutropenia","volume":"16","author":"J Pascoe","year":"2009","journal-title":"Curr Opin Hematol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"S11","DOI":"10.1038\/sj.bjc.6605270","article-title":"Prevention of febrile neutropenia: use of prophylactic antibiotics. (2009)","volume":"101","author":"M Cullen","year":"2009","journal-title":"Br J Cancer"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1056\/NEJM199404283301717","article-title":"Escherichia coli resistant to fluoroquinolones in patients with cancer and neutropenia","volume":"330","author":"A Cometta","year":"1994","journal-title":"N Engl J Med"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1093\/clinids\/20.3.557","article-title":"Emergence of quinolone-resistant Escherichia coli bacteremia in neutropenic patients with cancer who have received prophylactic norfloxacin","volume":"20","author":"J Carratala","year":"1995","journal-title":"Clin Infect Dis"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1002\/cncr.11044","article-title":"Ciprofloxacin prophylaxis in patients with acute leukemia and granulocytopenia in an area with a high prevalence of ciprofloxacin-resistant Escherichia coli","volume":"97","author":"L Gomez","year":"2003","journal-title":"Cancer"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1086\/428732","article-title":"Impact of fluoroquinolone prophylaxis on reduced infection-related mortality among patients with neutropenia and hematologic malignancies","volume":"40","author":"S Reuter","year":"2005","journal-title":"Clin Infect Dis"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1007\/s10096-007-0428-8","article-title":"Effects on spectrum and susceptibility patterns of isolates causing bloodstream infection by restriction of fluoroquinolone prophylaxis in a hematology-oncology unit","volume":"27","author":"T Saito","year":"2008","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1007\/s10096-011-1489-2","article-title":"The role of prophylactic antimicrobials during autologous stem cell transplantation: a single-center experience","volume":"31","author":"BS Sohn","year":"2012","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1128\/AAC.40.2.503","article-title":"Emergence of fluoroquinolone-resistant Escherichia coli in fecal flora of cancer patients receiving norfloxacin prophylaxis","volume":"40","author":"J Carratala","year":"1996","journal-title":"Antimicrob Agents Chemother"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1093\/jac\/44.1.117","article-title":"Incidence and clinical impact of fluoroquinolone-resistant Escherichia coli in the faecal flora of cancer patients treated with high dose chemotherapy and ciprofloxacin prophylaxis","volume":"44","author":"S Perea","year":"1999","journal-title":"J Antimicrob Chemother"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"e56","DOI":"10.1093\/cid\/cir073","article-title":"Clinical practice guideline for the use of antimicrobial agents in neutropenic patients with cancer: 2010 update by the infectious diseases society of america","volume":"52","author":"AG Freifeld","year":"2011","journal-title":"Clin Infect Dis"},{"key":"ref16","unstructured":"National Committee for Clinical Laboratory Standards. (2004) Performance Standards for Antimicrobial Susceptibility Testing. 14th Informational Supplement. Wayne, Pennsylvania: NCCLS"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"S25","DOI":"10.1086\/383048","article-title":"Changes in the etiology of bacteremia in febrile neutropenic patients and the susceptibilities of the currently isolated pathogens","volume":"39","author":"R Ramphal","year":"2004","journal-title":"Clin Infect Dis"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1038\/sj.bmt.1705591","article-title":"The clinical impact of antibacterial prophylaxis and cycling antibiotics for febrile neutropenia in a hematological malignancy and transplantation unit","volume":"39","author":"M Craig","year":"2007","journal-title":"Bone Marrow Transplant"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"e277","DOI":"10.1016\/j.ijid.2010.12.010","article-title":"Clinical impact of fluoroquinolone prophylaxis in neutropenic patients with hematological malignancies","volume":"15","author":"Y Chong","year":"2011","journal-title":"Int J Infect Dis"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/j.mib.2006.08.011","article-title":"The CTX-M beta-lactamase pandemic","volume":"9","author":"R Canton","year":"2006","journal-title":"Curr Opin Microbiol"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.1016\/j.meegid.2011.06.001","article-title":"Genetic evolution and clinical impact in extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae","volume":"11","author":"Y Chong","year":"2011","journal-title":"Infect Genet Evol"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"131","DOI":"10.3109\/10428194.2010.518655","article-title":"Audit of fluoroquinolone prophylaxis against chemotherapy-induced febrile neutropenia in a hospital with highly prevalent fluoroquinolone resistance","volume":"52","author":"ES Ng","year":"2011","journal-title":"Leuk Lymphoma"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1097\/QCO.0b013e32834cf054","article-title":"Fluoroquinolones, antimicrobial resistance and neutropenic cancer patients","volume":"24","author":"EJ Bow","year":"2011","journal-title":"Curr Opin Infect Dis"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1097\/QCO.0b013e3283398dc1","article-title":"Extended-spectrum [beta]-lactamase producing Escherichia coli: changing epidemiology and clinical impact","volume":"23","author":"J Oteo","year":"2010","journal-title":"Curr Opin Infect Dis"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"1038","DOI":"10.1099\/jmm.0.059279-0","article-title":"Community spread of extended-spectrum beta-lactamase-producing Escherichia coli, Klebsiella pneumoniae and Proteus mirabilis: a long-term study in Japan","volume":"62","author":"Y Chong","year":"2013","journal-title":"J Med Microbiol"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0085210","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,6]],"date-time":"2019-08-06T18:53:05Z","timestamp":1565117585000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0085210"}},"subtitle":[],"editor":[{"given":"Mark Alexander","family":"Webber","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2014,1,22]]},"references-count":25,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2014,1,22]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0085210","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,1,22]]}}}