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PLoS Biol DOI:<ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/dx.doi.org\/10.1371\/journal.pbio.0040145\" xlink:type=\"simple\">10.1371\/journal.pbio.0040145<\/ext-link>.","DOI":"10.1371\/journal.pbio.0040145"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"2184","DOI":"10.1139\/z00-162","article-title":"Modeling the role of songbirds and rodents in the ecology of Lyme disease","volume":"78","author":"AR Giardina","year":"2000","journal-title":"Can J Zool"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1073\/pnas.0233733100","article-title":"The ecology of infectious disease: Effects of host diversity and community composition on Lyme disease risk","volume":"100","author":"K LoGiudice","year":"2003","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1098\/rspb.2007.1208","article-title":"Conspicuous impacts of inconspicuous hosts on the Lyme disease epidemic","volume":"275","author":"D Brisson","year":"2008","journal-title":"Proc Biol Sci"},{"key":"ref18","first-page":"507","article-title":"Vectorial capacity of North American <italic>Ixodes<\/italic> ticks","volume":"57","author":"A Spielman","year":"1984","journal-title":"Yale J Biol Med"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1093\/oxfordjournals.aje.a115306","article-title":"Comparing the relative potential of rodents as reservoirs of the Lyme disease spirochete (<italic>Borrelia burgdorferi<\/italic>)","volume":"130","author":"TN Mather","year":"1989","journal-title":"Am J Epidemiol"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"5331","DOI":"10.1128\/AEM.00014-06","article-title":"Genetic diversity of <italic>Borrelia burgdorferi<\/italic> sensu stricto in <italic>Peromyscus leucopus<\/italic>, the primary reservoir of Lyme disease in a region of endemicity in southern Maryland","volume":"72","author":"JM Anderson","year":"2006","journal-title":"Appl Environ Microbiol"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1093\/jmedent\/45.1.139","article-title":"Estimating reservoir competence of <italic>Borrelia burgdorferi<\/italic> hosts: Prevalence and infectivity, sensitivity, and specificity","volume":"45","author":"JL Brunner","year":"2008","journal-title":"J Med Entomol"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1046\/j.1523-1739.2000.99014.x","article-title":"Biodiversity and disease risk: The case of Lyme disease","volume":"14","author":"RS Ostfeld","year":"2000","journal-title":"Conserv Biol"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1093\/jmedent\/42.3.445","article-title":"Reservoir competence of native North American birds for the Lyme disease spirochete, <italic>Borrelia burgdorferi<\/italic>","volume":"42","author":"HS Ginsberg","year":"2005","journal-title":"J Med Entomol"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"604","DOI":"10.3201\/eid1204.051016","article-title":"Epidemic spread of Lyme borreliosis, northeastern United States","volume":"12","author":"K Hanincov\u00e1","year":"2006","journal-title":"Emerg Infect Dis"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"3911","DOI":"10.1098\/rspb.2009.1159","article-title":"Hosts as ecological traps for the vector of Lyme disease","volume":"276","author":"F Keesing","year":"2009","journal-title":"Proc Biol Sci"},{"key":"ref26","unstructured":"Ostfeld RS (2011) Lyme disease: the ecology of a complex system. 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(2011) Associations between <italic>Ixodes scapularis<\/italic> ticks and small mammal hosts in a newly endemic zone in southeastern Canada: implications for <italic>Borrelia burgdorferi<\/italic> transmission. Ticks Tick Borne Dis DOI:<ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/dx.doi.org\/10.1016\/j.ttbdis.2011.03.005\" xlink:type=\"simple\">10.1016\/j.ttbdis.2011.03.005<\/ext-link>.","DOI":"10.1016\/j.ttbdis.2011.03.005"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.epidem.2009.06.002","article-title":"Biodiversity and Lyme disease: Dilution or amplification","volume":"1","author":"NH Ogden","year":"2009","journal-title":"Epidemics"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1093\/jmedent\/32.5.730","article-title":"Suppression of subadult <italic>Ixodes scapularis<\/italic> (Acari: Ixodidae) following removal of leaf litter","volume":"32","author":"TL Schulze","year":"1995","journal-title":"J Med Entomol"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1093\/jmedent\/33.4.619","article-title":"Microclimate-dependent survival of unfed adult <italic>Ixodes scapularis<\/italic> (Acari: Ixodidae) in nature: life cycle and study design implications","volume":"33","author":"MR Bertrand","year":"1996","journal-title":"J Med Entomol"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1603\/0022-2585-41.4.622","article-title":"Investigation of relationships between temperature and developmental rates of tick <italic>Ixodes scapularis<\/italic> (Acari: Ixodidae) in the laboratory and field","volume":"41","author":"NH Ogden","year":"2004","journal-title":"J Med Entomol"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1093\/jmedent\/32.2.143","article-title":"Survival and development of <italic>Ixodes scapularis<\/italic> (Acari: Ixodidae) under various climatic conditions in Ontario, Canada","volume":"32","author":"LR Lindsay","year":"1995","journal-title":"J Med Entomol"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1603\/0022-2585-39.6.842","article-title":"Vertical movement and posture of blacklegged tick (Acari: Ixodidae) nymphs as a function of temperature and relative humidity in laboratory experiments","volume":"39","author":"SG Vail","year":"2002","journal-title":"J Med Entomol"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.ijpara.2005.08.016","article-title":"Climate change and the potential for range expansion of the Lyme disease vector <italic>Ixodes scapularis<\/italic> in Canada","volume":"36","author":"NH Ogden","year":"2006","journal-title":"Int J Parasitol"},{"key":"ref38","unstructured":"Ogden NH, Lindsay LR, Leighton PA (2013) Predicting the rate of invasion of the agent of Lyme disease <italic>Borrelia burgdorferi<\/italic>. J Appl Ecol DOI:\u2013<ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/dx.doi.org\/10.1111\/13652664.12050\" xlink:type=\"simple\">10.1111\/1365\u20132664.12050<\/ext-link>."},{"key":"ref39","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1093\/jmedent\/43.3.600","article-title":"<italic>Ixodes scapularis<\/italic> ticks collected by passive surveillance in Canada: Analysis of geographic distribution and infection with Lyme borreliosis agent <italic>Borrelia burgdorferi<\/italic>","volume":"43","author":"NH Ogden","year":"2006","journal-title":"J Med Entomol"},{"key":"ref40","first-page":"1","article-title":"The rising challenge of Lyme borreliosis in Canada","volume":"34(1)","author":"NH Ogden","year":"2008","journal-title":"Canada Communicable Disease Report"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"1230","DOI":"10.1001\/jama.1991.03470090064033","article-title":"The geographic spread and temporal increase of the Lyme disease epidemic","volume":"266","author":"DJ White","year":"1991","journal-title":"JAMA"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"538","DOI":"10.4269\/ajtmh.2001.65.538","article-title":"Lyme disease in New York State: Spatial pattern at a regional scale","volume":"65","author":"S Glavanakov","year":"2001","journal-title":"Am J Trop Med Hyg"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"2070","DOI":"10.1128\/JCM.40.6.2070-2073.2002","article-title":"Reassessment of a Midwestern Lyme disease focus for <italic>Borrelia burgdorferi<\/italic> and the human granulocytic ehrlichiosis agent","volume":"40","author":"CA Jackson","year":"2002","journal-title":"J Clin Microbiol"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"15013","DOI":"10.1073\/pnas.0903810106","article-title":"Phylogeography of <italic>Borrelia burgdorferi<\/italic> in the eastern United States reflects multiple independent Lyme disease emergence events","volume":"106","author":"AG Hoen","year":"2009","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1503\/cmaj.080148","article-title":"The emergence of Lyme disease in Canada","volume":"180","author":"NH Ogden","year":"2009","journal-title":"CMAJ"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1289\/ehp.0901766","article-title":"Active and passive surveillance and phylogenetic analysis of <italic>Borrelia burgdorferi<\/italic> elucidate the process of Lyme disease risk emergence in Canada","volume":"118","author":"NH Ogden","year":"2010","journal-title":"Environ Health Perspect"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1007\/s10393-010-0287-0","article-title":"Invasion of the Lyme disease vector <italic>Ixodes scapularis<\/italic>: Implications for <italic>Borrelia burgdorferi<\/italic> endemicity","volume":"7","author":"SA Hamer","year":"2010","journal-title":"EcoHealth"},{"key":"ref48","unstructured":"Leighton PA, Koffi JK, Pelcat Y, Lindsay LR, Ogden NH (2012) Predicting the speed of tick invasion: an empirical model of range expansion for the Lyme disease vector <italic>Ixodes scapularis<\/italic> in Canada. J Appl Ecol DOI:\u2013<ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/dx.doi.org\/10.1111\/j.13652664.2012.02112.x\" xlink:type=\"simple\">10.1111\/j.1365\u20132664.2012.02112.x<\/ext-link>."},{"key":"ref49","first-page":"1","article-title":"Summary of notifiable diseases \u2013 United States, 2008","volume":"57","author":"PA Hall-Baker","year":"2010","journal-title":"Morbidity and Mortality Weekly Reports"},{"key":"ref50","unstructured":"Werden L (2012) Factors Affecting the Abundance of Blacklegged Ticks (<italic>Ixodes scapularis<\/italic>) and the Prevalence of <italic>Borrelia burgdorferi<\/italic> in Ticks and Small Mammals in the Thousand Islands Region. M.Sc. thesis. Guelph: University of Guelph."},{"key":"ref51","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1093\/jmedent\/35.3.189","article-title":"Survival and development of the different life stages of <italic>Ixodes scapularis<\/italic> (Acari: Ixodidae) held within four habitats on Long Point, Ontario, Canada","volume":"35","author":"LR Lindsay","year":"1998","journal-title":"J Med Entomol"},{"key":"ref52","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1093\/jmedent\/27.2.196","article-title":"Duration and regulation of the developmental cycle of <italic>Ixodes dammini<\/italic> (Acari: Ixodidae)","volume":"27","author":"B Yuval","year":"1990","journal-title":"J Med Entomol"},{"key":"ref53","doi-asserted-by":"crossref","unstructured":"Durden LA, Keirans JE (1996) Nymphs of the genus <italic>Ixodes<\/italic> (Acari: Ixodidae) of the United States: Taxonomy, identification key, distribution, hosts and medical\/veterinary importance. Maryland: Thomas Say Publications in Entomology: Entomological Society of America. 95 p.","DOI":"10.4182\/MAMR9602"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1603\/ME12093","article-title":"Harvested white-tailed deer as sentinel hosts for early establishing <italic>Ixodes scapularis<\/italic> populations and risk from vector-borne zoonoses in southeastern Canada","volume":"50","author":"C Bouchard","year":"2013","journal-title":"J Med Entomol"},{"key":"ref55","unstructured":"Eder T (2002) Mammals of Ontario. Edmonton: Lone Pine Publishing. 215 p."},{"key":"ref56","unstructured":"Thompson L (2010) A pathway analysis candidate gene approach to seasonal reproductive timing in mammals with a focus on period and casein kinase 1 in <italic>Peromyscus<\/italic>. M.Sc. thesis. Peterborough: Trent University."},{"key":"ref57","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1089\/153036601750137688","article-title":"Effects of acorn production and mouse abundance on abundance and <italic>Borrelia burgdorferi<\/italic> infection prevalence of nymphal <italic>Ixodes scapularis<\/italic> ticks","volume":"1","author":"RS Ostfeld","year":"2001","journal-title":"Vector Borne Zoonotic Dis"},{"key":"ref58","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1603\/033.046.0508","article-title":"Precipitation and temperature as predictors of the local abundance of <italic>Ixodes scapularis<\/italic> (Acari: Ixodidae) nymphs","volume":"46","author":"TL Schulze","year":"2009","journal-title":"J Med Entomol"},{"key":"ref59","doi-asserted-by":"crossref","first-page":"597","DOI":"10.2307\/3798941","article-title":"The pellet-group count technique for big game trend, census, and distribution: A review","volume":"32","author":"DJ Neff","year":"1968","journal-title":"J Wildl Manage"},{"key":"ref60","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/S0304-3800(00)00354-9","article-title":"Predictive habitat distribution models in ecology","volume":"135","author":"A Guisan","year":"2000","journal-title":"Ecol Modell"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1111\/j.1466-8238.2010.00526.x","article-title":"Field and climate-based model for predicting the density of host-seeking nymphal <italic>Ixodes scapularis<\/italic>, an important vector of tick-borne disease agents in the eastern United States","volume":"19","author":"MA Diuk-Wasser","year":"2010","journal-title":"Glob Ecol Biogeogr"},{"key":"ref62","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1111\/j.2007.0906-7590.05171.x","article-title":"Methods to account for spatial autocorrelation in the analysis of species distributional data: a review","volume":"30","author":"CF Dormann","year":"2007","journal-title":"Ecography"},{"key":"ref63","unstructured":"Burnham KP, Anderson DR (2002) Model selection and multimodel inference: A practical information-theoretic approach, Second edition. New York: Springer. 488 p."},{"key":"ref64","doi-asserted-by":"crossref","unstructured":"Zuur A, Leno EN, Walker N, Saveliev AA, Smith GM (2009) Mixed effects models and extensions in ecology with R. New York: Springer Science+Business Media LLC. 574 p.","DOI":"10.1007\/978-0-387-87458-6"},{"key":"ref65","doi-asserted-by":"crossref","unstructured":"Quinn GP, Keough MJ (2002) Experimental design and data analysis for biologists. Cambridge: Cambridge University Press. 556 p.","DOI":"10.1017\/CBO9780511806384"},{"key":"ref66","unstructured":"R Development Core Team (2011) R: A language and environment for statistical computing. R Foundation for Statistical Computing. Available: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.R-project.org\/\" xlink:type=\"simple\">http:\/\/www.R-project.org\/<\/ext-link>. Accessed 1 December 2011."},{"key":"ref67","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1603\/0022-2585-41.5.842","article-title":"A dispersal model for the range expansion of blacklegged tick (Acari: Ixodidae)","volume":"41","author":"NK Madhav","year":"2004","journal-title":"J Med Entomol"},{"key":"ref68","doi-asserted-by":"crossref","first-page":"1780","DOI":"10.1128\/AEM.01982-07","article-title":"Role of migratory birds in introduction and range expansion of <italic>Ixodes scapularis<\/italic> ticks and of <italic>Borrelia burgdorferi<\/italic> and <italic>Anaplasma phagocytophilum<\/italic> in Canada","volume":"74","author":"NH Ogden","year":"2008","journal-title":"Appl Environ Microbiol"},{"key":"ref69","unstructured":"Christopherson RW, Byrne ML (2009) Geosystems: an introduction to physical geography, Second Canadian edition. Toronto: Pearson Education Canada. 736 p."},{"key":"ref70","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1046\/j.1523-1739.2003.01260.x","article-title":"Effect of forest fragmentation on Lyme disease risk","volume":"17","author":"BF Allan","year":"2003","journal-title":"Conserv Biol"},{"key":"ref71","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.2307\/1383014","article-title":"Effects of forest fragmentation on population attributes of white-footed mice and eastern chipmunks","volume":"79","author":"TE Nupp","year":"1998","journal-title":"J Mammal"},{"key":"ref72","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1139\/cjz-77-8-1247","article-title":"Demography of <italic>Peromyscus leucopus<\/italic> populations on habitat patches: The role of dispersal","volume":"77","author":"DT Krohne","year":"1999","journal-title":"Can J Zool"},{"key":"ref73","doi-asserted-by":"crossref","unstructured":"Bowman J, Cappuccino N, Fahrig L (2002) Patch size and population density: the effect of immigration behavior. Conservation Ecology 6(1): 9. Available: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.consecol.org\/vol6\/iss1\/art9\" xlink:type=\"simple\">http:\/\/www.consecol.org\/vol6\/iss1\/art9<\/ext-link>. Accessed 28 February 2013.","DOI":"10.5751\/ES-00354-060109"},{"key":"ref74","unstructured":"Van Wieren J, Broadfoot J, Gonzales E (2008) St. Lawrence Islands National Park hyperabundant deer management plan. Mallorytown: Parks Canada. 25 p."},{"key":"ref75","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1007\/BF00048285","article-title":"Nymphal survival and habitat distribution of <italic>Ixodes scapularis<\/italic> and <italic>Amblyomma americanum<\/italic> ticks (Acari: Ixodidae) on Fire Island, New York, USA","volume":"20","author":"HS Ginsberg","year":"1996","journal-title":"Exp Appl Acarol"},{"key":"ref76","doi-asserted-by":"crossref","first-page":"289","DOI":"10.3201\/eid0803.010166","article-title":"Predicting the risk of Lyme disease: Habitat suitability for <italic>Ixodes scapularis<\/italic> in the north central United States","volume":"8","author":"M Guerra","year":"2002","journal-title":"Emerg Infect Dis"},{"key":"ref77","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1093\/jmedent\/33.5.805","article-title":"Relationship between <italic>Ixodes ricinus<\/italic> density and prevalence of infection with <italic>Borrelia<\/italic>-like spirochetes and density of infected ticks","volume":"33","author":"L T\u00e4lleklint","year":"1996","journal-title":"J Med Entomol"},{"key":"ref78","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/S0934-8840(98)80123-0","article-title":"Lyme borreliosis habitat assessment","volume":"287","author":"JS Gray","year":"1998","journal-title":"Zentralbl Bakteriol"},{"key":"ref79","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1017\/S0031182012000200","article-title":"Pangloss revisited: a critique of the dilution effect and the biodiversity-buffers-disease paradigm","volume":"139","author":"SE Randolph","year":"2012","journal-title":"Parasitology"},{"key":"ref80","doi-asserted-by":"crossref","first-page":"2960","DOI":"10.1098\/rspb.2010.2402","article-title":"Impact of the experimental removal of lizards on Lyme disease risk","volume":"278","author":"A Swei","year":"2011","journal-title":"Proc Biol Sci"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0085640","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,22]],"date-time":"2024-05-22T19:45:33Z","timestamp":1716407133000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0085640"}},"subtitle":[],"editor":[{"given":"J. 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