{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T04:37:08Z","timestamp":1792730228263,"version":"4.5.0"},"reference-count":31,"publisher":"Public Library of Science (PLoS)","issue":"2","license":[{"start":{"date-parts":[[2014,2,14]],"date-time":"2014-02-14T00:00:00Z","timestamp":1392336000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0088521","type":"journal-article","created":{"date-parts":[[2014,2,14]],"date-time":"2014-02-14T22:01:26Z","timestamp":1392415286000},"page":"e88521","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":107,"title":["Hypothermic Oxygenated Machine Perfusion Prevents Arteriolonecrosis of the Peribiliary Plexus in Pig Livers Donated after Circulatory Death"],"prefix":"10.1371","volume":"9","author":[{"given":"Sanna","family":"op den Dries","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael E.","family":"Sutton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Negin","family":"Karimian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marieke T.","family":"de Boer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janneke","family":"Wiersema-Buist","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annette S. H.","family":"Gouw","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henri G. D.","family":"Leuvenink","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ton","family":"Lisman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert J.","family":"Porte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2014,2,14]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1002\/lt.21853","article-title":"Liver transplantation following donation after cardiac death: An analysis using matched pairs","volume":"15","author":"JK Pine","year":"2009","journal-title":"Liver Transpl"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"2868","DOI":"10.1016\/j.transproceed.2012.09.077","article-title":"Outcomes of liver transplantations using donations after circulatory death: A single-center experience","volume":"44","author":"N Meurisse","year":"2012","journal-title":"Transplant Proc"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1097\/01.tp.0000297945.83430.ce","article-title":"Biliary complications after liver transplantation from maastricht category-2 non-heart-beating donors","volume":"85","author":"F Suarez","year":"2008","journal-title":"Transplantation"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1002\/bjs.7043","article-title":"Similar liver transplantation survival with selected cardiac death donors and brain death donors","volume":"97","author":"J Dubbeld","year":"2010","journal-title":"Br J Surg"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1002\/lt.21165","article-title":"Nonanastomotic biliary strictures after liver transplantation, part 2: Management, outcome, and risk factors for disease progression","volume":"13","author":"RC Verdonk","year":"2007","journal-title":"Liver Transpl"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1002\/lt.21509","article-title":"Biliary strictures following liver transplantation: Past, present and preventive strategies","volume":"14","author":"S Sharma","year":"2008","journal-title":"Liver Transpl"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1111\/j.1432-2277.2009.00947.x","article-title":"Incidence of and risk factors for ischemic-type biliary lesions following orthotopic liver transplantation","volume":"23","author":"C Heidenhain","year":"2010","journal-title":"Transpl Int"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1097\/TP.0b013e318223a384","article-title":"Protection of bile ducts in liver transplantation: Looking beyond ischemia","volume":"92","author":"S Op den Dries","year":"2011","journal-title":"Transplantation"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1053\/jlts.2003.50098","article-title":"Hepatic artery thrombosis after adult liver transplantation","volume":"9","author":"BJ Stange","year":"2003","journal-title":"Liver Transpl"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1097\/00007890-199309000-00001","article-title":"The greater vulnerability of bile duct cells to reoxygenation injury than to anoxia. implications for the pathogenesis of biliary strictures after liver transplantation","volume":"56","author":"K Noack","year":"1993","journal-title":"Transplantation"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1007\/s00428-012-1245-8","article-title":"Histological examination and evaluation of donor bile ducts received during orthotopic liver transplantation\u2013a morphological clue to ischemic-type biliary lesion?","volume":"461","author":"T Hansen","year":"2012","journal-title":"Virchows Arch"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1111\/j.1600-6143.2009.02932.x","article-title":"Hypothermic machine preservation in human liver transplantation: The first clinical series","volume":"10","author":"JV Guarrera","year":"2010","journal-title":"Am J Transplant"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1111\/ajt.12187","article-title":"Ex vivo normothermic machine perfusion and viability testing of discarded human donor livers","volume":"13","author":"S Op den Dries","year":"2013","journal-title":"Am J Transplant"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1097\/MOT.0b013e328351083d","article-title":"Is extracorporeal hypothermic machine perfusion of the liver better than the \u2018good old icebox\u2019?","volume":"17","author":"C Bae","year":"2012","journal-title":"Curr Opin Organ Transplant"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1111\/j.1600-6143.2008.02165.x","article-title":"Machine perfusion for \u2018marginal\u2019 liver grafts","volume":"8","author":"P Dutkowski","year":"2008","journal-title":"Am J Transplant"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/j.jhep.2012.10.004","article-title":"Protective mechanisms of end-ischemic cold machine perfusion in DCD liver grafts","volume":"58","author":"A Schlegel","year":"2013","journal-title":"J Hepatol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1016\/S0022-2275(20)40709-6","article-title":"Re-evaluation of the 3 alpha-hydroxysteroid dehydrogenase assay for total bile acids in bile","volume":"19","author":"SD Turley","year":"1978","journal-title":"J Lipid Res"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1006\/cryo.2000.2276","article-title":"Bile analysis as a tool for assessing integrity of biliary epithelial cells after cold ischemia\u2013reperfusion of rat livers","volume":"41","author":"K Vajdova","year":"2000","journal-title":"Cryobiology"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1097\/TP.0b013e318170f5f7","article-title":"The role of bile salt toxicity in the pathogenesis of bile duct injury after non-heart-beating porcine liver transplantation","volume":"85","author":"MJ Yska","year":"2008","journal-title":"Transplantation"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"3512","DOI":"10.3748\/wjg.v12.i22.3512","article-title":"Biliary wound healing, ductular reactions, and IL-6\/gp130 signaling in the development of liver disease","volume":"12","author":"AJ Demetris","year":"2006","journal-title":"World J Gastroenterol"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1007\/s00534-005-1081-1","article-title":"Intrahepatic biliary strictures after liver transplantation","volume":"13","author":"S Nishida","year":"2006","journal-title":"J Hepatobiliary Pancreat Surg"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1016\/j.jhep.2012.12.022","article-title":"Bile duct damage after cold storage of deceased donor livers predicts biliary complications after liver transplantation","volume":"58","author":"SM Brunner","year":"2013","journal-title":"J Hepatol"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1016\/j.jhep.2013.02.023","article-title":"The origin of biliary strictures after liver transplantation: Is it the amount of epithelial injury or insufficient regeneration that counts?","volume":"58","author":"N Karimian","year":"2013","journal-title":"J Hepatol"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1097\/TP.0b013e31825774d7","article-title":"Hypothermic oxygenated machine perfusion in porcine donation after circulatory determination of death liver transplant","volume":"94","author":"C Fondevila","year":"2012","journal-title":"Transplantation"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"3455","DOI":"10.1016\/j.transproceed.2011.09.029","article-title":"Attempt to rescue discarded human liver grafts by end ischemic hypothermic oxygenated machine perfusion","volume":"43","author":"K Vekemans","year":"2011","journal-title":"Transplant Proc"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1097\/00007890-200203150-00008","article-title":"Advantages of normothermic perfusion over cold storage in liver preservation","volume":"73","author":"CJ Imber","year":"2002","journal-title":"Transplantation"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/2047-1440-1-6","article-title":"A simplified subnormothermic machine perfusion system restores ischemically damaged liver grafts in a rat model of orthotopic liver transplantation","volume":"1","author":"TA Berendsen","year":"2012","journal-title":"Transplant Res"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"2026","DOI":"10.1016\/j.transproceed.2012.06.014","article-title":"Subnormothermic machine perfusion for non-heart-beating donor liver grafts preservation in a swine model: A new strategy to increase the donor pool?","volume":"44","author":"E Gringeri","year":"2012","journal-title":"Transplant Proc"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1097\/MOT.0b013e328351082a","article-title":"Extracorporeal machine liver perfusion: Are we warming up?","volume":"17","author":"AJ Hessheimer","year":"2012","journal-title":"Curr Opin Organ Transplant"},{"key":"ref30","doi-asserted-by":"crossref","unstructured":"Dutkowski P, Schlegel A, de Oliveira M, Mullhaupt B, Clavien PA (2013) HOPE for human liver grafts obtained from donors after cardiac death. J Hepatol In press. DOI: 10.1016\/j.jhep.2013.11.023.","DOI":"10.1016\/j.jhep.2013.11.023"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1111\/ajt.12224","article-title":"Normothermic acellular ex vivo liver perfusion reduces liver and bile duct injury of pig livers retrieved after cardiac death","volume":"13","author":"MU Boehnert","year":"2013","journal-title":"Am J Transplant"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0088521","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,26]],"date-time":"2022-03-26T17:08:38Z","timestamp":1648314518000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0088521"}},"subtitle":[],"editor":[{"given":"Simon","family":"Afford","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2014,2,14]]},"references-count":31,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2014,2,14]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0088521","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,2,14]]}}}