{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T20:56:45Z","timestamp":1791665805736,"version":"4.3.4"},"reference-count":35,"publisher":"Public Library of Science (PLoS)","issue":"3","license":[{"start":{"date-parts":[[2014,3,6]],"date-time":"2014-03-06T00:00:00Z","timestamp":1394064000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0089375","type":"journal-article","created":{"date-parts":[[2014,3,6]],"date-time":"2014-03-06T21:37:01Z","timestamp":1394141821000},"page":"e89375","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":40,"title":["Characterisation of Leukocytes in a Human Skin Blister Model of Acute Inflammation and Resolution"],"prefix":"10.1371","volume":"9","author":[{"given":"William","family":"Jenner","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madhur","family":"Motwani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristin","family":"Veighey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justine","family":"Newson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatsiana","family":"Audzevich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Nicolaou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon","family":"Murphy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raymond","family":"MacAllister","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Derek W.","family":"Gilroy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2014,3,6]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1038\/nri915","article-title":"Anti-inflammatory lipid mediators and insights into the resolution of inflammation","volume":"2","author":"T Lawrence","year":"2002","journal-title":"Nature reviews Immunology"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF01630479","article-title":"New insights into the mode of action of anti-inflammatory drugs","volume":"44","author":"JR Vane","year":"1995","journal-title":"Inflammation research : official journal of the European Histamine Research Society [et al]"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1038\/ni1276","article-title":"Resolution of inflammation: the beginning programs the end","volume":"6","author":"CN Serhan","year":"2005","journal-title":"Nature immunology"},{"key":"ref4","first-page":"181","article-title":"Air-pouch models of inflammation and modifications for the study of granuloma-mediated cartilage degradation","volume":"225","author":"P Colville-Nash","year":"2003","journal-title":"Methods in molecular biology"},{"key":"ref5","first-page":"129","article-title":"Models of acute inflammation in the ear","volume":"225","author":"M Gabor","year":"2003","journal-title":"Methods in molecular biology"},{"key":"ref6","first-page":"123","article-title":"Pleural models of inflammation: immune and nonimmune","volume":"225","author":"AR Moore","year":"2003","journal-title":"Methods in molecular biology"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/S0076-6879(09)05417-2","article-title":"Chapter 17. Zymosan-induced peritonitis as a simple experimental system for the study of inflammation","volume":"461","author":"JL Cash","year":"2009","journal-title":"Methods Enzymol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1016\/S0140-6736(06)68265-2","article-title":"Defective acute inflammation in Crohn&apos;s disease: a clinical investigation","volume":"367","author":"JBM Daniel","year":"2006","journal-title":"The Lancet"},{"key":"ref9","doi-asserted-by":"crossref","unstructured":"Kuhns DB, DeCarlo E, Hawk DM, Gallin JI (1992) Dynamics of the cellular and humoral components of the inflammatory response elicited in skin blisters in humans.","DOI":"10.1172\/JCI115775"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/S0022-1759(01)00467-7","article-title":"Cantharidin blisters: a technique for investigating leukocyte trafficking and cytokine production at sites of inflammation in humans","volume":"257","author":"RM Day","year":"2001","journal-title":"J Immunol Methods"},{"issue":"no. 1","key":"ref11","first-page":"4","article-title":"Assessment of leukocyte trafficking in humans using the cantharidin blister model","volume":"vol. 1","author":"WJGD Jenner","year":"2012","journal-title":"J R Soc Med Cardio"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1002\/rcm.3331","article-title":"Simultaneous lipidomic analysis of three families of bioactive lipid mediators leukotrienes, resolvins, protectins and related hydroxy-fatty acids by liquid chromatography\/electrospray ionisation tandem mass spectrometry","volume":"22","author":"M Masoodi","year":"2008","journal-title":"Rapid Commun Mass Spectrom"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"3023","DOI":"10.1002\/rcm.2697","article-title":"Lipidomic analysis of twenty-seven prostanoids and isoprostanes by liquid chromatography\/electrospray tandem mass spectrometry","volume":"20","author":"M Masoodi","year":"2006","journal-title":"Rapid Commun Mass Spectrom"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1002\/cyto.a.22104","article-title":"CD14, CD16 and HLA-DR reliably identifies human monocytes and their subsets in the context of pathologically reduced HLA-DR expression by CD14(hi)\/CD16(neg) monocytes: Expansion of CD14(hi)\/CD16(pos) and contraction of CD14(lo)\/CD16(pos) monocytes in acute liver failure","volume":"81","author":"RD Abeles","year":"2012","journal-title":"Cytometry Part A : the journal of the International Society for Analytical Cytology"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.immuni.2012.04.012","article-title":"Human tissues contain CD141hi cross-presenting dendritic cells with functional homology to mouse CD103+ nonlymphoid dendritic cells","volume":"37","author":"M Haniffa","year":"2012","journal-title":"Immunity"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.4049\/jimmunol.153.3.1254","article-title":"Neutrophil apoptosis is associated with a reduction in CD16 (Fc gamma RIII) expression","volume":"153","author":"I Dransfield","year":"1994","journal-title":"Journal of immunology"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"270","DOI":"10.3389\/fimmu.2012.00270","article-title":"Emerging roles of eosinophils and eosinophil-derived lipid mediators in the resolution of inflammation","volume":"3","author":"Y Isobe","year":"2012","journal-title":"Frontiers in immunology"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"8842","DOI":"10.1073\/pnas.1000373107","article-title":"Dichotomy in duration and severity of acute inflammatory responses in humans arising from differentially expressed proresolution pathways","volume":"107","author":"T Morris","year":"2010","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1111\/j.1365-2125.2011.04020.x","article-title":"Validation of the cantharidin-induced skin blister as an in vivo model of inflammation","volume":"72","author":"PH Dinh","year":"2011","journal-title":"British journal of clinical pharmacology"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1096\/fj.10-170027","article-title":"Eosinophils promote resolution of acute peritonitis by producing proresolving mediators in mice","volume":"25","author":"T Yamada","year":"2011","journal-title":"FASEB journal : official publication of the Federation of American Societies for Experimental Biology"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1038\/nrd3838","article-title":"Targeting eosinophils in allergy, inflammation and beyond","volume":"12","author":"PC Fulkerson","year":"2013","journal-title":"Nat Rev Drug Discov"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"e16","DOI":"10.1182\/blood-2010-12-326355","article-title":"Gene expression profiling reveals the defining features of the classical, intermediate, and nonclassical human monocyte subsets","volume":"118","author":"KL Wong","year":"2011","journal-title":"Blood"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"2053","DOI":"10.1002\/eji.1830230902","article-title":"The novel subset of CD14+\/CD16+ blood monocytes exhibits features of tissue macrophages","volume":"23","author":"HW Ziegler-Heitbrock","year":"1993","journal-title":"Eur J Immunol"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1126\/science.1142883","article-title":"Monitoring of blood vessels and tissues by a population of monocytes with patrolling behavior","volume":"317","author":"C Auffray","year":"2007","journal-title":"Science"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.immuni.2010.08.012","article-title":"Human CD14dim monocytes patrol and sense nucleic acids and viruses via TLR7 and TLR8 receptors","volume":"33","author":"J Cros","year":"2010","journal-title":"Immunity"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"3170","DOI":"10.1182\/blood.V82.10.3170.3170","article-title":"The novel subset of CD14+\/CD16+ blood monocytes is expanded in sepsis patients","volume":"82","author":"G Fingerle","year":"1993","journal-title":"Blood"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"e11049","DOI":"10.1371\/journal.pone.0011049","article-title":"Functional contribution of elevated circulating and hepatic non-classical CD14CD16 monocytes to inflammation and human liver fibrosis","volume":"5","author":"HW Zimmermann","year":"2010","journal-title":"PloS one"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1093\/rheumatology\/keh112","article-title":"Expression of Fcgamma and complement receptors on peripheral blood monocytes in systemic lupus erythematosus and rheumatoid arthritis","volume":"43","author":"AL Hepburn","year":"2004","journal-title":"Rheumatology"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1160\/TH04-02-0095","article-title":"CD14+CD16+ monocytes in coronary artery disease and their relationship to serum TNF-alpha levels","volume":"92","author":"A Schlitt","year":"2004","journal-title":"Thrombosis and haemostasis"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1002\/eji.201243256","article-title":"Dressed not to kill: CD16+ monocytes impair immune defence against tuberculosis","volume":"43","author":"G Lugo-Villarino","year":"2013","journal-title":"European journal of immunology"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/j.tube.2011.04.002","article-title":"Increased frequency and cell death of CD16+ monocytes with Mycobacterium tuberculosis infection","volume":"91","author":"D Castano","year":"2011","journal-title":"Tuberculosis"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1046\/j.1365-2249.1996.907600.x","article-title":"Generalized immune activation in pulmonary tuberculosis: co-activation with HIV infection","volume":"103","author":"G Vanham","year":"1996","journal-title":"Clinical and experimental immunology"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"3418","DOI":"10.1002\/eji.1830251232","article-title":"CD14lowCD16high: a cytokine-producing monocyte subset which expands during human immunodeficiency virus infection","volume":"25","author":"N Thieblemont","year":"1995","journal-title":"European journal of immunology"},{"key":"ref34","article-title":"Evolution of the Macrophage CD163 Phenotype and Cytokine Profiles in a Human Model of Resolving Inflammation","author":"BJ Evans","year":"2013","journal-title":"International Journal of Inflammation 2013"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1002\/(SICI)1097-0320(19990501)36:1<77::AID-CYTO10>3.0.CO;2-F","article-title":"High affinity binding of fluorescein isothiocyanate to eosinophils detected by laser scanning cytometry: a potential source of error in analysis of blood samples utilizing fluorescein-conjugated reagents in flow cytometry","volume":"36","author":"E Bedner","year":"1999","journal-title":"Cytometry"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0089375","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,11]],"date-time":"2023-07-11T00:19:46Z","timestamp":1689034786000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0089375"}},"subtitle":[],"editor":[{"given":"John","family":"Wallace","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2014,3,6]]},"references-count":35,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2014,3,6]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0089375","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,3,6]]}}}