{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T18:07:02Z","timestamp":1785434822714,"version":"3.56.0"},"reference-count":75,"publisher":"Public Library of Science (PLoS)","issue":"2","license":[{"start":{"date-parts":[[2014,2,21]],"date-time":"2014-02-21T00:00:00Z","timestamp":1392940800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0089663","type":"journal-article","created":{"date-parts":[[2014,2,21]],"date-time":"2014-02-21T22:26:41Z","timestamp":1393021601000},"page":"e89663","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":33,"title":["5-HT1A\/1B Receptors as Targets for Optimizing Pigmentary Responses in C57BL\/6 Mouse Skin to Stress"],"prefix":"10.1371","volume":"9","author":[{"given":"Hua-Li","family":"Wu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Si-Lin","family":"Pang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiong-Zhen","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min-Xuan","family":"Cai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Shang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2014,2,21]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1210\/er.2012-1092","article-title":"Key Role of CRF in the Skin Stress Response System","volume":"34","author":"AT Slominski","year":"2013","journal-title":"Endocr Rev"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"3","DOI":"10.4161\/derm.3.1.14617","article-title":"Neuroendocrinology of the skin: An overview and selective analysis","volume":"3","author":"MA Zmijewski","year":"2011","journal-title":"Dermatoendocrinol"},{"key":"ref3","first-page":"457","article-title":"Neuroendocrinology of the skin","volume":"21","author":"A Slominski","year":"2000","journal-title":"Endocr Rev"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1111\/1523-1747.ep12606218","article-title":"Catecholamines in human keratinocyte differentiation","volume":"104","author":"KU Schallreuter","year":"1995","journal-title":"J Invest Dermatol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1006\/jtbi.1993.1142","article-title":"Melanocytes as \u201csensory\u201d and regulatory cells in the epidermis","volume":"164","author":"A Slominski","year":"1993","journal-title":"J Theor Biol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"1697","DOI":"10.1038\/sj.jid.5700104","article-title":"Neuroimmunology of stress: skin takes center stage","volume":"126","author":"PC Arck","year":"2006","journal-title":"J Invest Dermatol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1111\/j.1600-0625.2009.00892.x","article-title":"Neuroendocrine activity of the melanocyte","volume":"18","author":"A Slominski","year":"2009","journal-title":"Exp Dermatol"},{"key":"ref8","first-page":"1","article-title":"Sensing the environment: regulation of local and global homeostasis by the skin\u2019s neuroendocrine system","volume":"212","author":"AT Slominski","year":"2012","journal-title":"Adv Anat Embryol Cell Biol"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1056\/NEJM199908123410706","article-title":"The biology of hair follicles","volume":"341","author":"R Paus","year":"1999","journal-title":"N Engl J Med"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.sder.2006.01.002","article-title":"Biology of the hair follicle: the basics","volume":"25","author":"K Krause","year":"2006","journal-title":"Semin Cutan Med Surg"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1046\/j.0022-202x.2001.01377.x","article-title":"A comprehensive guide for the accurate classification of murine hair follicles in distinct hair cycle stages","volume":"117","author":"S Muller-Rover","year":"2001","journal-title":"J Invest Dermatol"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1016\/S0002-9440(10)63877-1","article-title":"Stress inhibits hair growth in mice by induction of premature catagen development and deleterious perifollicular inflammatory events via neuropeptide substance P-dependent pathways","volume":"162","author":"PC Arck","year":"2003","journal-title":"Am J Pathol"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1034\/j.1600-0625.2002.120403.x","article-title":"Intermittent foot shock stress prolongs the telogen stage in the hair cycle of mice","volume":"12","author":"E Aoki","year":"2003","journal-title":"Exp Dermatol"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1111\/j.1600-0625.2007.00558.x","article-title":"Foot shock stress prolongs the telogen stage of the spontaneous hair cycle in a non-depilated mouse model","volume":"16","author":"M Katayama","year":"2007","journal-title":"Exp Dermatol"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1002\/hup.1011","article-title":"The psychoneuroimmunology of depression","volume":"24","author":"BE Leonard","year":"2009","journal-title":"Hum Psychopharmacol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0165-0173(93)90005-K","article-title":"Physiopharmacological interactions between stress hormones and central serotonergic systems","volume":"18","author":"F Chaouloff","year":"1993","journal-title":"Brain Res Brain Res Rev"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1097\/00004850-199603001-00004","article-title":"Serotonin: current understanding and the way forward","volume":"1","author":"TG Dinan","year":"1996","journal-title":"Int Clin Psychopharmacol"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0074-7742(06)77002-7","article-title":"Serotonin and brain: evolution, neuroplasticity, and homeostasis","volume":"77","author":"EC Azmitia","year":"2007","journal-title":"Int Rev Neurobiol"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/S0091-3057(01)00746-8","article-title":"Molecular, pharmacological and functional diversity of 5-HT receptors","volume":"71","author":"D Hoyer","year":"2002","journal-title":"Pharmacol Biochem Behav"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"3369","DOI":"10.1097\/00001756-199911080-00021","article-title":"5-HT1A autoreceptor desensitization by chronic ultramild stress in mice","volume":"10","author":"L Lanfumey","year":"1999","journal-title":"Neuroreport"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.psychres.2008.07.006","article-title":"Decreased expression of serotonin 1A receptor in the dentate gyrus in association with chronic mild stress: a rat model of post-stroke depression","volume":"170","author":"SH Wang","year":"2009","journal-title":"Psychiatry Res"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1007\/s007020170077","article-title":"Brain monoamine receptors in a chronic unpredictable stress model in rats","volume":"108","author":"G Ossowska","year":"2001","journal-title":"J Neural Transm"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1096\/fj.04-2079rev","article-title":"The cutaneous serotoninergic\/melatoninergic system: securing a place under the sun","volume":"19","author":"A Slominski","year":"2005","journal-title":"FASEB J"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/S0925-4439(03)00124-8","article-title":"Tryptophan hydroxylase expression in human skin cells","volume":"1639","author":"A Slominski","year":"2003","journal-title":"Biochim Biophys Acta"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/j.jaci.2006.09.003","article-title":"Human mast cells are capable of serotonin synthesis and release","volume":"119","author":"NM Kushnir-Sukhov","year":"2007","journal-title":"J Allergy Clin Immunol"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1096\/fj.01-0952fje","article-title":"Serotoninergic and melatoninergic systems are fully expressed in human skin","volume":"16","author":"A Slominski","year":"2002","journal-title":"FASEB J"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1111\/j.1600-0625.2007.00670.x","article-title":"The skin as a mirror of the soul: exploring the possible roles of serotonin","volume":"17","author":"K Nordlind","year":"2008","journal-title":"Exp Dermatol"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1152\/physrev.00044.2003","article-title":"Melanin pigmentation in mammalian skin and its hormonal regulation","volume":"84","author":"A Slominski","year":"2004","journal-title":"Physiol Rev"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1002\/jcp.10287","article-title":"Functional activity of serotoninergic and melatoninergic systems expressed in the skin","volume":"196","author":"A Slominski","year":"2003","journal-title":"J Cell Physiol"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/0016-6480(80)90090-8","article-title":"Further evidence that serotonin may be a physiological melanocyte-stimulating hormone-releasing factor in the lizard Anolis carolinensis","volume":"40","author":"HP Levitin","year":"1980","journal-title":"Gen Comp Endocrinol"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1111\/j.1365-2133.2011.10490.x","article-title":"Serotonin induces melanogenesis via serotonin receptor 2A","volume":"165","author":"HJ Lee","year":"2011","journal-title":"Br J Dermatol"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1111\/j.1600-0625.2012.01531.x","article-title":"Up-regulation of melanin synthesis by the antidepressant fluoxetine","volume":"21","author":"S Liao","year":"2012","journal-title":"Exp Dermatol"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"3171","DOI":"10.4049\/jimmunol.142.9.3171","article-title":"A new interpretation of the involvement of serotonin in delayed-type hypersensitivity. Serotonin-2 receptor antagonists inhibit contact sensitivity by an effect on T cells","volume":"142","author":"JC Ameisen","year":"1989","journal-title":"J Immunol"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1097\/01.all.0000244793.03239.40","article-title":"Anxiety in allergy and atopic dermatitis","volume":"6","author":"H Hashizume","year":"2006","journal-title":"Curr Opin Allergy Clin Immunol"},{"key":"ref35","first-page":"683","article-title":"[Tryptophan metabolism in vitiligo]","volume":"22","author":"Kh Kurbanov","year":"1976","journal-title":"Vopr Med Khim"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1152\/physrev.1954.34.1.113","article-title":"Growth of the hair","volume":"34","author":"HB Chase","year":"1954","journal-title":"Physiol Rev"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1111\/1523-1747.ep12460956","article-title":"Differential expression and activity of melanogenesis-related proteins during induced hair growth in mice","volume":"96","author":"A Slominski","year":"1991","journal-title":"J Invest Dermatol"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1084\/jem.191.8.1423","article-title":"Chronic restraint stress promotes lymphocyte apoptosis by modulating CD95 expression","volume":"191","author":"D Yin","year":"2000","journal-title":"J Exp Med"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1016\/j.pbb.2008.03.005","article-title":"Fluoxetine alters feeding behavior and leptin levels in chronically-stressed rats","volume":"90","author":"GD Gamaro","year":"2008","journal-title":"Pharmacol Biochem Behav"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"994","DOI":"10.2460\/ajvr.2003.64.994","article-title":"Comparative bioavailability of fluoxetine after transdermal and oral administration to healthy cats","volume":"64","author":"J Ciribassi","year":"2003","journal-title":"Am J Vet Res"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"E144","DOI":"10.1208\/pt060222","article-title":"Feasibility of transdermal delivery of fluoxetine","volume":"6","author":"DK Parikh","year":"2005","journal-title":"AAPS PharmSciTech"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1016\/j.ijpharm.2013.08.080","article-title":"Effect of permeation enhancers on transdermal delivery of fluoxetine: in vitro and in vivo evaluation","volume":"456","author":"E Jung","year":"2013","journal-title":"Int J Pharm"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/S0014-2999(99)00580-4","article-title":"The serotonin precursor 5-hydroxytryptophan elevates serum leptin levels in mice","volume":"383","author":"J Yamada","year":"1999","journal-title":"Eur J Pharmacol"},{"key":"ref44","first-page":"24","article-title":"Lasting neurobehavioral abnormalities in rats after neonatal activation of serotonin 1A and 1B receptors: possible mechanisms for serotonin dysfunction in autistic spectrum disorders","volume":"24","author":"N Khatri","year":"2013","journal-title":"Psychopharmacology (Berl)"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.bbr.2013.02.032","article-title":"Head movement: a novel serotonin-sensitive behavioral endpoint for tail suspension test analysis","volume":"246","author":"A Lockridge","year":"2013","journal-title":"Behav Brain Res"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1373\/clinchem.2003.025841","article-title":"Optimum collection and storage conditions for ghrelin measurements: octanoyl modification of ghrelin is rapidly hydrolyzed to desacyl ghrelin in blood samples","volume":"50","author":"H Hosoda","year":"2004","journal-title":"Clin Chem"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"4509","DOI":"10.1210\/en.2007-0034","article-title":"Stimulation of growth hormone release by 5-hydroxytryptamine (5-HT) in cultured rat anterior pituitary cell aggregates: evidence for mediation by 5-HT2B, 5-HT7, 5-HT1B, and ketanserin-sensitive receptors","volume":"148","author":"A Papageorgiou","year":"2007","journal-title":"Endocrinology"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1038\/sj.jid.5701024","article-title":"Murine vibrissae cultured in serum-free medium reinitiate anagen","volume":"128","author":"J Lee","year":"2008","journal-title":"J Invest Dermatol"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"3139","DOI":"10.1182\/blood-2006-10-052787","article-title":"Serotonin provides an accessory signal to enhance T-cell activation by signaling through the 5-HT7 receptor","volume":"109","author":"M Leon-Ponte","year":"2007","journal-title":"Blood"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/j.biocel.2012.11.008","article-title":"Interleukin-18 augments growth ability of primary human melanocytes by PTEN inactivation through the AKT\/NF-kappaB pathway","volume":"45","author":"J Zhou","year":"2013","journal-title":"Int J Biochem Cell Biol"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1034\/j.1600-0749.2002.02014.x","article-title":"Modulation of melanogenesis by aloesin: a competitive inhibitor of tyrosinase","volume":"15","author":"K Jones","year":"2002","journal-title":"Pigment Cell Res"},{"key":"ref52","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1111\/j.1600-0749.1992.tb00562.x","article-title":"Melanocyte-stimulating properties of arachidonic acid metabolites: possible role in postinflammatory pigmentation","volume":"5","author":"Y Tomita","year":"1992","journal-title":"Pigment Cell Res"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"3035","DOI":"10.1038\/sj.onc.1206443","article-title":"Microphthalamia-associated transcription factor: a critical regulator of pigment cell development and survival","volume":"22","author":"HR Widlund","year":"2003","journal-title":"Oncogene"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/j.phrs.2012.06.009","article-title":"Simultaneous alterations of brain and plasma serotonin concentrations and liver cytochrome P450 in rats fed on a tryptophan-free diet","volume":"66","author":"M Kot","year":"2012","journal-title":"Pharmacol Res"},{"key":"ref55","first-page":"260","article-title":"Tryptophan-Free Diets: A Physiological Tool to Study Brain Serotonin Function","volume":"15","author":"F Fadda","year":"2000","journal-title":"News Physiol Sci"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1046\/j.1523-1747.2003.12326.x","article-title":"Stress augmented ultraviolet-irradiation-induced pigmentation","volume":"121","author":"K Inoue","year":"2003","journal-title":"J Invest Dermatol"},{"key":"ref57","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1126\/science.166.3910.1274","article-title":"Corticosterone regulation of tryptophan hydroxylase in midbrain of the rat","volume":"166","author":"EC Azmitia Jr","year":"1969","journal-title":"Science"},{"key":"ref58","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1007\/s10571-006-9024-1","article-title":"Identification of genes regulated by chronic social stress in the rat dorsal raphe nucleus","volume":"26","author":"N Abumaria","year":"2006","journal-title":"Cell Mol Neurobiol"},{"key":"ref59","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1111\/j.1476-5381.2011.01630.x","article-title":"5-HT receptors as novel targets for optimizing pigmentary responses in dorsal skin melanophores of frog, Hoplobatrachus tigerinus","volume":"165","author":"SA Ali","year":"2012","journal-title":"Br J Pharmacol"},{"key":"ref60","doi-asserted-by":"crossref","first-page":"14299","DOI":"10.1074\/jbc.M005363200","article-title":"Heterodimerization of mineralocorticoid and glucocorticoid receptors at a novel negative response element of the 5-HT1A receptor gene","volume":"276","author":"XM Ou","year":"2001","journal-title":"J Biol Chem"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/S0304-3940(99)00439-5","article-title":"Homologous regulation of 5-HT1A receptor mRNA in adult rat hippocampal dentate gyrus","volume":"270","author":"J Huang","year":"1999","journal-title":"Neurosci Lett"},{"key":"ref62","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/S0923-1811(00)00133-X","article-title":"Effect of high population density environment on skin barrier function in mice","volume":"25","author":"A Aioi","year":"2001","journal-title":"J Dermatol Sci"},{"key":"ref63","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1007\/s00403-002-0350-y","article-title":"Expression of serotonin receptors in allergic contact eczematous human skin","volume":"294","author":"L Lundeberg","year":"2002","journal-title":"Arch Dermatol Res"},{"key":"ref64","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1056\/NEJMra041867","article-title":"The serotonin syndrome","volume":"352","author":"EW Boyer","year":"2005","journal-title":"N Engl J Med"},{"key":"ref65","doi-asserted-by":"crossref","first-page":"2457","DOI":"10.1096\/fj.11-197137","article-title":"Blunted epidermal L-tryptophan metabolism in vitiligo affects immune response and ROS scavenging by Fenton chemistry, part 1: Epidermal H2O2\/ONOO(-)-mediated stress abrogates tryptophan hydroxylase and dopa decarboxylase activities, leading to low serotonin and melatonin levels","volume":"26","author":"KU Schallreuter","year":"2012","journal-title":"FASEB J"},{"key":"ref66","doi-asserted-by":"crossref","first-page":"e61574","DOI":"10.1371\/journal.pone.0061574","article-title":"Chronic restraint stress inhibits hair growth via substance P mediated by reactive oxygen species in mice","volume":"8","author":"N Liu","year":"2013","journal-title":"PLoS One"},{"key":"ref67","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/0165-5728(90)90015-F","article-title":"Restraint stress-induced elevations in plasma corticosterone and beta-endorphin are not accompanied by alterations in immune function","volume":"28","author":"CM Flores","year":"1990","journal-title":"J Neuroimmunol"},{"key":"ref68","first-page":"447","article-title":"Stress-responsive hypothalamic-nucleus accumbens regulation may vary depending on stressors","volume":"50","author":"SJ Noh","year":"2012","journal-title":"Indian J Exp Biol"},{"key":"ref69","first-page":"147","article-title":"Serotonin (5-HT) precursor loading with 5-hydroxy-l-tryptophan (5-HTP) reduces locomotor activation produced by (+)-amphetamine in the rat","volume":"114","author":"MH Baumann","year":"2011","journal-title":"Drug Alcohol Depend"},{"key":"ref70","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1159\/000117687","article-title":"L-5HTP treatment and serum 5-HT level after L-5-HTP loading on depressed patients","volume":"5","author":"M Kaneko","year":"1979","journal-title":"Neuropsychobiology"},{"key":"ref71","doi-asserted-by":"crossref","first-page":"2867","DOI":"10.1016\/S0024-3205(02)02138-0","article-title":"Evidence for involvement of 5-hydroxytryptamine(1B) autoreceptors in the enhancement of serotonin turnover in the mouse brain following repeated treatment with fluoxetine","volume":"71","author":"C Stenfors","year":"2002","journal-title":"Life Sci"},{"key":"ref72","first-page":"49","article-title":"Brain tryptophan metabolism remained unaltered in restraint stressed rats following fluoxetine administration","volume":"18","author":"S Dawood","year":"2005","journal-title":"Pak J Pharm Sci"},{"key":"ref73","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1007\/s00213-005-0213-2","article-title":"Fluoxetine and norfluoxetine stereospecifically and selectively increase brain neurosteroid content at doses that are inactive on 5-HT reuptake","volume":"186","author":"G Pinna","year":"2006","journal-title":"Psychopharmacology (Berl)"},{"key":"ref74","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1046\/j.1365-2826.2000.00509.x","article-title":"Regulation of central corticosteroid receptors following short-term activation of serotonin transmission by 5-hydroxy-L-tryptophan or fluoxetine","volume":"12","author":"A Semont","year":"2000","journal-title":"J Neuroendocrinol"},{"key":"ref75","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/0304-3940(93)90494-6","article-title":"The hypophagic effect of restraint stress in rats can be mediated by 5-HT2 receptors in the paraventricular nucleus of the hypothalamus","volume":"152","author":"G Grignaschi","year":"1993","journal-title":"Neurosci Lett"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0089663","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,24]],"date-time":"2024-05-24T13:19:27Z","timestamp":1716556767000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0089663"}},"subtitle":[],"editor":[{"given":"Andrzej T.","family":"Slominski","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2014,2,21]]},"references-count":75,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2014,2,21]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0089663","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,2,21]]}}}