{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T19:19:16Z","timestamp":1789586356334,"version":"build-2803163510"},"reference-count":23,"publisher":"Public Library of Science (PLoS)","issue":"3","license":[{"start":{"date-parts":[[2014,3,6]],"date-time":"2014-03-06T00:00:00Z","timestamp":1394064000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0090272","type":"journal-article","created":{"date-parts":[[2014,3,6]],"date-time":"2014-03-06T21:42:10Z","timestamp":1394142130000},"page":"e90272","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":25,"title":["Long Non-Coding RNA Expression Profiles in Hereditary Haemorrhagic Telangiectasia"],"prefix":"10.1371","volume":"9","author":[{"given":"Pernille M.","family":"T\u00f8rring","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin Jakob","family":"Larsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anette D.","family":"Kjeldsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lilian Bomme","family":"Ousager","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qihua","family":"Tan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaus","family":"Brusgaard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2014,3,6]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1136\/jmg.2009.069013","article-title":"International guidelines for the diagnosis and management of hereditary haemorrhagic telangiectasia","volume":"48","author":"ME Faughnan","year":"2011","journal-title":"J Med Genet"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1046\/j.1365-2796.2000.00725.x","article-title":"Prevalence of pulmonary arteriovenous malformations (PAVMs) and occurrence of neurological symptoms in patients with hereditary haemorrhagic telangiectasia (HHT)","volume":"248","author":"AD Kjeldsen","year":"2000","journal-title":"J Intern Med"},{"key":"ref3","first-page":"192","article-title":"Cerebral abscesses among Danish patients with hereditary haemorrhagic telangiectasia. Acta Neurol Scand","volume":"129(3)","author":"AD Kjeldsen","year":"2013","journal-title":"2014 Mar"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1046\/j.1365-2796.1999.00398.x","article-title":"Hereditary haemorrhagic telangiectasia: a population-based study of prevalence and mortality in Danish patients","volume":"245","author":"AD Kjeldsen","year":"1999","journal-title":"J Intern Med"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1111\/j.1399-0004.2004.00341.x","article-title":"Mutations in endoglin and in activin receptor-like kinase 1 among Danish patients with hereditary haemorrhagic telangiectasia","volume":"66","author":"K Brusgaard","year":"2004","journal-title":"Clin Genet"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1002\/humu.9345","article-title":"High frequency of ENG and ALK1\/ACVRL1 mutations in German HHT patients","volume":"25","author":"C Schulte","year":"2005","journal-title":"Hum Mutat"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1002\/humu.20017","article-title":"Molecular screening of ALK1\/ACVRL1 and ENG genes in hereditary hemorrhagic telangiectasia in France","volume":"23","author":"G Lesca","year":"2004","journal-title":"Hum Mutat"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"4018","DOI":"10.1038\/sj.emboj.7600386","article-title":"Endoglin promotes endothelial cell proliferation and TGF-beta\/ALK1 signal transduction","volume":"23","author":"F Lebrin","year":"2004","journal-title":"The EMBO journal"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"1743","DOI":"10.1093\/emboj\/21.7.1743","article-title":"Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors","volume":"21","author":"M-J Goumans","year":"2002","journal-title":"The EMBO journal"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/S0955-0674(99)00081-2","article-title":"Smads as transcriptional co-modulators","volume":"12","author":"L Attisano","year":"2000","journal-title":"Current opinion in cell biology"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"1775","DOI":"10.1101\/gr.132159.111","article-title":"The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression","volume":"22","author":"T Derrien","year":"2012","journal-title":"Genome Res"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"R162","DOI":"10.1093\/hmg\/ddq362","article-title":"Transcribed dark matter: meaning or myth","volume":"19","author":"CP Ponting","year":"2010","journal-title":"Hum Mol Genet"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"D146","DOI":"10.1093\/nar\/gkq1138","article-title":"lncRNAdb: a reference database for long noncoding RNAs","volume":"39","author":"PP Amaral","year":"2011","journal-title":"Nucleic Acids Res"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1002\/(SICI)1096-8628(20000306)91:1<66::AID-AJMG12>3.0.CO;2-P","article-title":"Diagnostic criteria for hereditary hemorrhagic telangiectasia (Rendu-Osler-Weber syndrome)","volume":"91","author":"CL Shovlin","year":"2000","journal-title":"Am J Med Genet"},{"key":"ref15","doi-asserted-by":"crossref","unstructured":"Torring PM, Brusgaard K, Ousager LB, Andersen PE, Kjeldsen AD (2013) National mutation study among Danish patients with Hereditary Haemorrhagic Telangiectasia. Clin Genet.2013 Sep 3. doi:<ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/dx.doi.org\/10.1111\/cge.12269\" xlink:type=\"simple\">10.1111\/cge.12269<\/ext-link>.","DOI":"10.1111\/cge.12269"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"2700","DOI":"10.1093\/bioinformatics\/btm412","article-title":"A comparison of background correction methods for two-colour microarrays","volume":"23","author":"ME Ritchie","year":"2007","journal-title":"Bioinformatics"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1038\/nbt.1630","article-title":"GREAT improves functional interpretation of cis-regulatory regions","volume":"28","author":"CY McLean","year":"2010","journal-title":"Nat Biotechnol"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1093\/bib\/bbs017","article-title":"Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration","volume":"14","author":"H Thorvaldsdottir","year":"2013","journal-title":"Brief Bioinform"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1038\/75556","article-title":"Gene ontology: tool for the unification of biology. The Gene Ontology Consortium","volume":"25","author":"M Ashburner","year":"2000","journal-title":"Nat Genet"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1086\/380314","article-title":"Mutations in a gene encoding a novel protein containing a phosphotyrosine-binding domain cause type 2 cerebral cavernous malformations","volume":"73","author":"CL Liquori","year":"2003","journal-title":"Am J Hum Genet"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1086\/379793","article-title":"Capillary malformation-arteriovenous malformation, a new clinical and genetic disorder caused by RASA1 mutations","volume":"73","author":"I Eerola","year":"2003","journal-title":"Am J Hum Genet"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1111\/j.1365-2362.2007.01824.x","article-title":"Altered endothelial gene expression associated with hereditary haemorrhagic telangiectasia","volume":"37","author":"B Thomas","year":"2007","journal-title":"Eur J Clin Invest"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1093\/hmg\/ddm069","article-title":"Gene expression fingerprinting for human hereditary hemorrhagic telangiectasia","volume":"16","author":"A Fernandez-L","year":"2007","journal-title":"Hum Mol Genet"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0090272","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,9]],"date-time":"2020-05-09T13:30:43Z","timestamp":1589031043000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0090272"}},"subtitle":[],"editor":[{"given":"Qiong","family":"Wu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2014,3,6]]},"references-count":23,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2014,3,6]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0090272","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,3,6]]}}}