{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T09:20:36Z","timestamp":1791192036423,"version":"4.1.0"},"reference-count":45,"publisher":"Public Library of Science (PLoS)","issue":"3","license":[{"start":{"date-parts":[[2014,3,10]],"date-time":"2014-03-10T00:00:00Z","timestamp":1394409600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0091257","type":"journal-article","created":{"date-parts":[[2014,3,10]],"date-time":"2014-03-10T20:45:59Z","timestamp":1394484359000},"page":"e91257","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":36,"title":["Preferential and Comprehensive Reconstitution of Severely Damaged Sciatic Nerve Using Murine Skeletal Muscle-Derived Multipotent Stem Cells"],"prefix":"10.1371","volume":"9","author":[{"given":"Tetsuro","family":"Tamaki","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maki","family":"Hirata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuichi","family":"Soeda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobuyuki","family":"Nakajima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kosuke","family":"Saito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenei","family":"Nakazato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshinori","family":"Okada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Hashimoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiyasu","family":"Uchiyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joji","family":"Mochida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2014,3,10]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1002\/(SICI)1097-4598(200006)23:6<863::AID-MUS4>3.0.CO;2-0","article-title":"Traumatic injury to peripheral nerves","volume":"23","author":"LR Robinson","year":"2000","journal-title":"Muscle Nerve"},{"key":"ref2","first-page":"287","article-title":"Peripheral mechanisms for the initiation of pain following trigeminal nerve injury","volume":"18","author":"PP Robinson","year":"2004","journal-title":"J Orofac Pain"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1113\/jphysiol.1943.sp004027","article-title":"Rate of regeneration of peripheral nerves in man","volume":"102","author":"HJ Seddon","year":"1943","journal-title":"J Physiol"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1002\/mus.880130903","article-title":"The anatomy and physiology of nerve injury","volume":"13","author":"S Sunderland","year":"1990","journal-title":"Muscle Nerve"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1615\/CritRevBiomedEng.v39.i2.20","article-title":"Biomedical engineering strategies for peripheral nerve repair: surgical applications, state of the art, and future challenges","volume":"39","author":"BJ Pfister","year":"2011","journal-title":"Crit Rev Biomed Eng"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1111\/j.1447-073x.2004.00090.x","article-title":"Schwann cells and endoneurial extracellular matrix molecules as potential cues for sorting of regenerated axons: a review","volume":"79","author":"P Dubovy","year":"2004","journal-title":"Anat Sci Int"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"257","DOI":"10.2174\/157015905774322507","article-title":"Potential of bone marrow stromal cells in applications for neuro-degenerative, neuro-traumatic and muscle degenerative diseases","volume":"3","author":"M Dezawa","year":"2005","journal-title":"Curr Neuropharmacol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"145","DOI":"10.3727\/096368910X522081","article-title":"Transplantation of olfactory ensheathing cells as adjunct cell therapy for peripheral nerve injury","volume":"20","author":"C Radtke","year":"2011","journal-title":"Cell Transplant"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.expneurol.2007.06.029","article-title":"Adipose-derived stem cells differentiate into a Schwann cell phenotype and promote neurite outgrowth in vitro","volume":"207","author":"PJ Kingham","year":"2007","journal-title":"Exp Neurol"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1007\/978-1-60761-938-3_6","article-title":"The blood-nerve barrier: structure and functional significance","volume":"686","author":"A Weerasuriya","year":"2011","journal-title":"Methods Mol Biol"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1083\/jcb.200112106","article-title":"Identification of myogenic-endothelial progenitor cells in the interstitial spaces of skeletal muscle","volume":"157","author":"T Tamaki","year":"2002","journal-title":"J Cell Biol"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0014-4827(03)00376-8","article-title":"Growth and differentiation potential of main- and side-population cells derived from murine skeletal muscle","volume":"291","author":"T Tamaki","year":"2003","journal-title":"Exp Cell Res"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"2857","DOI":"10.1161\/CIRCULATIONAHA.105.554832","article-title":"Functional recovery of damaged skeletal muscle through synchronized vasculogenesis, myogenesis, and neurogenesis by muscle-derived stem cells","volume":"112","author":"T Tamaki","year":"2005","journal-title":"Circulation"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1007\/s00418-007-0331-5","article-title":"Synchronized reconstitution of muscle fibers, peripheral nerves and blood vessels by murine skeletal muscle-derived CD34(-)\/45 (-) cells","volume":"128","author":"T Tamaki","year":"2007","journal-title":"Histochem Cell Biol"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"2283","DOI":"10.1634\/stemcells.2006-0746","article-title":"Clonal multipotency of skeletal muscle-derived stem cells between mesodermal and ectodermal lineage","volume":"25","author":"T Tamaki","year":"2007","journal-title":"Stem Cells"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1089\/scd.2008.0070","article-title":"Skeletal muscle-derived CD34+\/45- and CD34\u2212\/45- stem cells are situated hierarchically upstream of Pax7+ cells","volume":"17","author":"T Tamaki","year":"2008","journal-title":"Stem Cells Dev"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"956","DOI":"10.2174\/138161210790883408","article-title":"Plasticity and physiological role of stem cells derived from skeletal muscle interstitium: contribution to muscle fiber hyperplasia and therapeutic use","volume":"16","author":"T Tamaki","year":"2010","journal-title":"Curr Pharm Des"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"1771","DOI":"10.1046\/j.0953-816x.2001.01814.x","article-title":"Sciatic nerve regeneration in rats induced by transplantation of in vitro differentiated bone-marrow stromal cells","volume":"14","author":"M Dezawa","year":"2001","journal-title":"Eur J Neurosci"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1046\/j.0022-7722.2002.00012.x","article-title":"Central and peripheral nerve regeneration by transplantation of Schwann cells and transdifferentiated bone marrow stromal cells","volume":"77","author":"M Dezawa","year":"2002","journal-title":"Anat Sci Int"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1038\/modpathol.3800042","article-title":"Aberrant expression of tight junction-related proteins ZO-1, claudin-1 and occludin in synovial sarcoma: an immunohistochemical study with ultrastructural correlation","volume":"17","author":"SD Billings","year":"2004","journal-title":"Mod Pathol"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1369\/jhc.5A6671.2005","article-title":"Tight junction proteins and perineurial cells in neurofibromas","volume":"54","author":"KP Pummi","year":"2006","journal-title":"J Histochem Cytochem"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1097\/00005072-199411000-00006","article-title":"Regenerating axons enhance differentiation of perineurial-like cells involved in minifascicle formation in the injured peripheral nerve","volume":"53","author":"M Popovic","year":"1994","journal-title":"J Neuropathol Exp Neurol"},{"key":"ref23","doi-asserted-by":"crossref","DOI":"10.1016\/0303-8467(93)90040-N","article-title":"Perineurial cells are the first to traverse gaps of peripheral nerves in silicone tubes","volume":"95","author":"JM Schroder","year":"1993","journal-title":"Clin Neurol Neurosurg"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1046\/j.1365-2990.2000.00238.x","article-title":"Role of axon-deprived Schwann cells in perineurial regeneration in the rat sciatic nerve","volume":"26","author":"M Popovic","year":"2000","journal-title":"Neuropathol Appl Neurobiol"},{"key":"ref25","first-page":"411","article-title":"Regeneration of the perineurium across a surgically induced gap in a nerve encased in a plastic tube","volume":"3)","author":"F Scaravilli","year":"1984","journal-title":"J Anat 139 (Pt"},{"key":"ref26","first-page":"45","article-title":"The cellular response to nerve injury. II. Regeneration of the perineurium after nerve section","volume":"101","author":"PK Thomas","year":"1967","journal-title":"J Anat"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1007\/BF00294509","article-title":"Fine structural and immunohistochemical identification of perineurial cells connecting proximal and distal stumps of transected peripheral nerves at early stages of regeneration in silicone tubes","volume":"88","author":"J Weis","year":"1994","journal-title":"Acta Neuropathol"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.bbrc.2012.01.154","article-title":"Transplantation of induced pluripotent stem cell-derived neurospheres for peripheral nerve repair","volume":"419","author":"T Uemura","year":"2012","journal-title":"Biochem Biophys Res Commun"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/j.expneurol.2008.06.017","article-title":"Reduced NGF secretion by Schwann cells under the high glucose condition decreases neurite outgrowth of DRG neurons","volume":"213","author":"T Tosaki","year":"2008","journal-title":"Exp Neurol"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"4171","DOI":"10.1111\/j.1460-9568.2000.01312.x","article-title":"Endogenous BDNF is required for myelination and regeneration of injured sciatic nerve in rodents","volume":"12","author":"JY Zhang","year":"2000","journal-title":"Eur J Neurosci"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.jcomdis.2010.04.003","article-title":"The physiology of neural injury and regeneration: The role of neurotrophic factors","volume":"43","author":"T Gordon","year":"2010","journal-title":"J Commun Disord"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"9964","DOI":"10.1523\/JNEUROSCI.19-22-09964.1999","article-title":"Galectin-1 regulates initial axonal growth in peripheral nerves after axotomy","volume":"19","author":"H Horie","year":"1999","journal-title":"J Neurosci"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/S0896-6273(00)80166-X","article-title":"Ninjurin, a novel adhesion molecule, is induced by nerve injury and promotes axonal growth","volume":"17","author":"T Araki","year":"1996","journal-title":"Neuron"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1186\/1471-2202-12-58","article-title":"Ciliary neurotrophic factor promotes motor reinnervation of the musculocutaneous nerve in an experimental model of end-to-side neurorrhaphy","volume":"12","author":"P Dubovy","year":"2011","journal-title":"BMC Neurosci"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1097\/WNR.0b013e32832a09f8","article-title":"Cell type-specific STAT3 activation by gp130-related cytokines in the peripheral nerves","volume":"20","author":"L Wang","year":"2009","journal-title":"Neuroreport"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1002\/glia.21173","article-title":"Sox10 is required for Schwann-cell homeostasis and myelin maintenance in the adult peripheral nerve","volume":"59","author":"M Bremer","year":"2011","journal-title":"Glia"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1101\/gad.186601","article-title":"The transcription factor Sox10 is a key regulator of peripheral glial development","volume":"15","author":"S Britsch","year":"2001","journal-title":"Genes Dev"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1083\/jcb.200912142","article-title":"Sox10 is required for Schwann cell identity and progression beyond the immature Schwann cell stage","volume":"189","author":"M Finzsch","year":"2010","journal-title":"J Cell Biol"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1210\/er.2003-0027","article-title":"Vascular endothelial growth factor: basic science and clinical progress","volume":"25","author":"N Ferrara","year":"2004","journal-title":"Endocr Rev"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1089\/ars.2010.3533","article-title":"Hepatocyte growth factor induces a proangiogenic phenotype and mobilizes endothelial progenitor cells by activating Nox2","volume":"15","author":"K Schroder","year":"2011","journal-title":"Antioxid Redox Signal"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"1951","DOI":"10.1016\/j.clinph.2008.03.018","article-title":"Evaluation and management of peripheral nerve injury","volume":"119","author":"WW Campbell","year":"2008","journal-title":"Clin Neurophysiol"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"9958","DOI":"10.1073\/pnas.1733025100","article-title":"Nestin expression in hair follicle sheath progenitor cells","volume":"100","author":"L Li","year":"2003","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"17734","DOI":"10.1073\/pnas.0508440102","article-title":"Implanted hair follicle stem cells form Schwann cells that support repair of severed peripheral nerves","volume":"102","author":"Y Amoh","year":"2005","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1002\/jcb.22204","article-title":"Human hair follicle pluripotent stem (hfPS) cells promote regeneration of peripheral-nerve injury: an advantageous alternative to ES and iPS cells","volume":"107","author":"Y Amoh","year":"2009","journal-title":"J Cell Biochem"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/S0014-5793(97)00313-X","article-title":"\u2018Green mice\u2019 as a source of ubiquitous green cells","volume":"407","author":"M Okabe","year":"1997","journal-title":"FEBS Lett"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0091257","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,24]],"date-time":"2024-05-24T22:27:42Z","timestamp":1716589662000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0091257"}},"subtitle":[],"editor":[{"given":"Atsushi","family":"Asakura","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2014,3,10]]},"references-count":45,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2014,3,10]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0091257","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,3,10]]}}}