{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T15:45:44Z","timestamp":1791215144616,"version":"4.1.0"},"reference-count":78,"publisher":"Public Library of Science (PLoS)","issue":"3","license":[{"start":{"date-parts":[[2014,3,19]],"date-time":"2014-03-19T00:00:00Z","timestamp":1395187200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0092140","type":"journal-article","created":{"date-parts":[[2014,3,20]],"date-time":"2014-03-20T02:54:06Z","timestamp":1395284046000},"page":"e92140","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":51,"title":["Up-Regulation of the ATP-Binding Cassette Transporter A1 Inhibits Hepatitis C Virus Infection"],"prefix":"10.1371","volume":"9","author":[{"given":"Simone","family":"Bocchetta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Maillard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mami","family":"Yamamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire","family":"Gondeau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florian","family":"Douam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"St\u00e9phanie","family":"Lebreton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvie","family":"Lagaye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stanislas","family":"Pol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7ois","family":"Helle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wanee","family":"Plengpanich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryse","family":"Gu\u00e9rin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryline","family":"Bourgine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie Louise","family":"Michel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitri","family":"Lavillette","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Roingeard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wilfried","family":"le Goff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agata","family":"Budkowska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2014,3,19]]},"reference":[{"key":"ref1","first-page":"4","article-title":"Emerging therapies for the treatment of hepatitis C. EMBO Mol Med","volume":"6","author":"CM Lange","year":"2014"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1111\/j.1478-3231.2011.02699.x","article-title":"Direct acting antivirals for the treatment of chronic hepatitis C: one pill a day for tomorrow","volume":"32","author":"T Asselah","year":"2012","journal-title":"Liver International"},{"key":"ref3","first-page":"9","article-title":"New targets for antiviral therapy of chronic hepatitis C. Liver Int","volume":"32","author":"S Buhler","year":"2012"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/j.jhep.2010.04.015","article-title":"Hepatitis C virus replication cycle","volume":"53","author":"R Bartenschlager","year":"2010","journal-title":"J Hepatol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"e108","DOI":"10.1371\/journal.ppat.0030108","article-title":"Reliance of host cholesterol metabolic pathways for the life cycle of hepatitis C virus","volume":"3","author":"J Ye","year":"2007","journal-title":"PLoS Pathog"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.tem.2009.07.005","article-title":"Hepatitis C virus hijacks host lipid metabolism","volume":"21","author":"GH Syed","year":"2010","journal-title":"Trends Endocrinol Metab"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1007\/s00281-012-0356-2","article-title":"Lipids and HCV","volume":"35","author":"MF Bassendine","year":"2013","journal-title":"Semin Immunopathol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"12766","DOI":"10.1073\/pnas.96.22.12766","article-title":"Hepatitis C virus and other flaviviridae viruses enter cells via low density lipoprotein receptor","volume":"96","author":"V Agnello","year":"1999","journal-title":"Proc Nat Acad Sci U S A"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1096\/fj.05-4728fje","article-title":"The interaction of natural hepatitis C virus with human scavenger receptor SR-BI\/Cla1 is mediated by ApoB-containing lipoproteins","volume":"20","author":"P Maillard","year":"2006","journal-title":"Faseb J"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1099\/vir.0.008300-0","article-title":"Hepatitis C virus-cell entry: role of lipoproteins and cellular receptors","volume":"90","author":"ME Burlone","year":"2009","journal-title":"J Gen Virol"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"2561","DOI":"10.1073\/pnas.0409834102","article-title":"Hepatitis C virus RNA replication is regulated by host geranylgeranylation and fatty acids","volume":"102","author":"SB Kapadia","year":"2005","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1038\/ncb1631","article-title":"The lipid droplet is an important organelle for hepatitis C virus production","volume":"9","author":"Y Miyanari","year":"2007","journal-title":"Nat Cell Biol"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"5848","DOI":"10.1073\/pnas.0700760104","article-title":"Hepatitis C virus production by human hepatocytes dependent on assembly and secretion of very low-density lipoproteins","volume":"104","author":"H Huang","year":"2007","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"13783","DOI":"10.1128\/JVI.01091-07","article-title":"Human apolipoprotein e is required for infectivity and production of hepatitis C virus in cell culture","volume":"81","author":"KS Chang","year":"2007","journal-title":"J Virol"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"6919","DOI":"10.1128\/JVI.76.14.6919-6928.2002","article-title":"Characterization of low- and very-low-density hepatitis C virus RNA-containing particles","volume":"76","author":"P Andre","year":"2002","journal-title":"J Virol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"2418","DOI":"10.1128\/JVI.80.5.2418-2428.2006","article-title":"Association between hepatitis C virus and very-low-density lipoprotein (VLDL)\/LDL analyzed in iodixanol density gradients","volume":"80","author":"SU Nielsen","year":"2006","journal-title":"J Virol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"5404","DOI":"10.1128\/JVI.02529-09","article-title":"Gene expression profiling indicates the roles of host oxidative stress, apoptosis, lipid metabolism, and intracellular transport genes in the replication of hepatitis C virus","volume":"84","author":"S Blackham","year":"2010","journal-title":"J Virol"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1136\/gut.2009.192732","article-title":"Abnormalities of lipid metabolism in hepatitis C virus infection","volume":"59","author":"F Negro","year":"2010","journal-title":"Gut"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"e144","DOI":"10.1111\/j.1365-2893.2010.01394.x","article-title":"Serum lipids and their associations with viral levels and liver disease severity in a treatment-naive chronic hepatitis C type 1-infected cohort","volume":"18","author":"D Ramcharran","year":"2011","journal-title":"J Viral Hepat"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"1482","DOI":"10.1016\/j.jhep.2011.06.004","article-title":"HCV and the hepatic lipid pathway as a potential treatment target","volume":"55","author":"MF Bassendine","year":"2011","journal-title":"J Hepatol"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1086\/525287","article-title":"Targeting lipid metabolism in the treatment of hepatitis C virus infection","volume":"197","author":"F Amemiya","year":"2008","journal-title":"J Infect Dis"},{"key":"ref22","first-page":"374","article-title":"Initiation of hepatitis C virus infection is dependent on cholesterol and cooperativity between CD81 and scavenger receptor B type I. J Virol","volume":"81","author":"SB Kapadia","year":"2007"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"2571","DOI":"10.1128\/AAC.02593-12","article-title":"Phenothiazines inhibit hepatitis C virus entry, likely by increasing the fluidity of cholesterol-rich membranes","volume":"57","author":"AM Chamoun-Emanuelli","year":"2013","journal-title":"Antimic agents chemo"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1097\/00041433-200104000-00008","article-title":"Very-low-density lipoprotein assembly and secretion","volume":"12","author":"GS Shelness","year":"2001","journal-title":"Curr Opin Lipidol"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1152\/physrev.00005.2005","article-title":"ATP-binding cassette transporter A1: A cell cholesterol exporter that protects against cardiovascular disease","volume":"85","author":"JF Oram","year":"2005","journal-title":"Physiol Rev"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/j.bbalip.2009.03.011","article-title":"The cell cholesterol exporter ABCA1 as a protector from cardiovascular disease and diabetes","volume":"1791","author":"C Tang","year":"2009","journal-title":"Biochimica Et Biophysica Acta-Molecular and Cell Biology of Lipids"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1172\/JCI200523915","article-title":"Targeted inactivation of hepatic Abca1 causes profound hypoalphalipoproteinemia and kidney hypercatabolism of apoA-I","volume":"115","author":"JM Timmins","year":"2005","journal-title":"J Clin Invest"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"16178","DOI":"10.1074\/jbc.M709597200","article-title":"ATP-binding cassette A1-mediated lipidation of apolipoprotein A-I occurs at the plasma membrane and not in the endocytic compartments","volume":"283","author":"M Denis","year":"2008","journal-title":"J Biol Chem"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1038\/11921","article-title":"Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1","volume":"22","author":"S Rust","year":"1999","journal-title":"Nature Gen"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/j.chom.2013.03.006","article-title":"The antiviral effector IFITM3 disrupts intracellular cholesterol homeostasis to block viral entry","volume":"13","author":"S Amini-Bavil-Olyaee","year":"2013","journal-title":"Cell Host Microbe"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1042\/BC20090138","article-title":"Host-cell lipid rafts: a safe door for micro-organisms?","volume":"102","author":"FS Vieira","year":"2010","journal-title":"Biol Cell"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1038\/nm1268","article-title":"Production of infectious hepatitis C virus in tissue culture from a cloned viral genome","volume":"11","author":"T Wakita","year":"2005","journal-title":"Nat Med"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"e26637","DOI":"10.1371\/journal.pone.0026637","article-title":"Lipoprotein lipase inhibits hepatitis C virus (HCV) infection by blocking virus cell entry","volume":"6","author":"P Maillard","year":"2011","journal-title":"PLoS ONE"},{"key":"ref34","unstructured":"Gondeau C, Briolotti P, Razafy F, Duret C, Rubbo PA, <etal>et al<\/etal>.. (2013) In vitro infection of primary human hepatocytes by HCV-positive sera: insights on a highly relevant model. Gut. doi: 10.1136."},{"key":"ref35","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1002\/hep.25738","article-title":"Efficient replication of primary or culture hepatitis C virus isolates in human liver slices: a relevant ex vivo model of liver infection","volume":"56","author":"S Lagaye","year":"2012","journal-title":"Hepatology"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"8752","DOI":"10.1128\/JVI.02642-06","article-title":"Characterization of fusion determinants points to the involvement of three discrete regions of both E1 and E2 glycoproteins in the membrane fusion process of hepatitis C virus","volume":"81","author":"D Lavillette","year":"2007","journal-title":"J Virol"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"29545","DOI":"10.1074\/jbc.M803819200","article-title":"Selective roles for cholesterol and actin in compartmentalization of different proteins in the Golgi and plasma membrane of polarized cells","volume":"283","author":"S Lebreton","year":"2008","journal-title":"J Biol Chem"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"4001","DOI":"10.1242\/jcs.036038","article-title":"Different GPI-attachment signals affect the oligomerisation of GPI-anchored proteins and their apical sorting","volume":"121","author":"S Paladino","year":"2008","journal-title":"J Cell Sci"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"1930","DOI":"10.1161\/ATVBAHA.109.194548","article-title":"Stimulation of cholesterol efflux by LXR agonists in cholesterol-loaded human macrophages is ABCA1-dependent but ABCG1-independent","volume":"29","author":"S Larrede","year":"2009","journal-title":"Art Thromb Vasc Biol"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S1388-1981(02)00355-4","article-title":"VLDL-induced triglyceride accumulation in human macrophages is mediated by modulation of LPL lipolytic activity in the absence of change in LPL mass","volume":"1631","author":"D Milosavljevic","year":"2003","journal-title":"Biochim Biophys Acta"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1194\/jlr.M500255-JLR200","article-title":"Reevaluation of the role of the multidrug-resistant P-glycoprotein in cellular cholesterol homeostasis","volume":"47","author":"W Le Goff","year":"2006","journal-title":"J Lipid Res"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"3075","DOI":"10.1099\/vir.0.81334-0","article-title":"Development and characterization of a transient-replication assay for the genotype 2a hepatitis C virus subgenomic replicon","volume":"86","author":"P Targett-Adams","year":"2005","journal-title":"J Gen Virol"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/S0022-2275(20)35376-1","article-title":"A density gradient ultracentrifugal procedure for the isolation of the major lipoprotein classes from human serum","volume":"22","author":"MJ Chapman","year":"1981","journal-title":"J Lipid Res"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1677\/JOE-09-0271","article-title":"Liver X receptor in cholesterol metabolism","volume":"204","author":"C Zhao","year":"2010","journal-title":"J Endocrinol"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.plipres.2010.03.002","article-title":"The liver X receptor: control of cellular lipid homeostasis and beyond Implications for drug design","volume":"49","author":"MH Oosterveer","year":"2010","journal-title":"Prog Lipid Res"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"34144","DOI":"10.1074\/jbc.M110.108100","article-title":"ATP-binding cassette transporter A1 mediates the beneficial effects of the liver X receptor agonist GW3965 on object recognition memory and amyloid burden in amyloid precursor protein\/presenilin 1 mice","volume":"285","author":"JJ Donkin","year":"2010","journal-title":"J Biol Chem"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1194\/jlr.M017079","article-title":"Nascent HDL formation in hepatocytes and role of ABCA1, ABCG1, and SR-BI","volume":"53","author":"A Ji","year":"2012","journal-title":"J Lipid Res"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.bbrc.2012.04.022","article-title":"ABCA1 upregulating apolipoproein M expression mediates via the RXR\/LXR pathway in HepG2 cells","volume":"421","author":"D Di","year":"2012","journal-title":"Biochem Biophys Res Com"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"21092","DOI":"10.1074\/jbc.M110.104836","article-title":"Claudin association with CD81 defines hepatitis C virus entry","volume":"285","author":"HJ Harris","year":"2010","journal-title":"J Biol Chem"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"31242","DOI":"10.1074\/jbc.M112.365924","article-title":"Characterization of hepatitis C virus particle subpopulations reveals multiple usage of the scavenger receptor BI for entry steps","volume":"287","author":"VL Dao Thi","year":"2012","journal-title":"J Biol Chem"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"2428","DOI":"10.1194\/jlr.M700206-JLR200","article-title":"Identification of an ABCA1-dependent phospholipid-rich plasma membrane apolipoprotein A-I binding site for nascent HDL formation: implications for current models of HDL biogenesis","volume":"48","author":"HH Hassan","year":"2007","journal-title":"J Lipid Res"},{"key":"ref52","doi-asserted-by":"crossref","first-page":"1890","DOI":"10.1194\/jlr.M026674","article-title":"Nascent high density lipoproteins formed by ABCA1 resemble lipid rafts and are structurally organized by three apoA-I monomers","volume":"53","author":"MG Sorci-Thomas","year":"2012","journal-title":"J Lipid Res"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"36091","DOI":"10.1074\/jbc.M602247200","article-title":"ATP-binding cassette transporter A1 expression disrupts raft membrane microdomains through its ATPase-related functions","volume":"281","author":"YD Landry","year":"2006","journal-title":"J Biol Chem"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"1775","DOI":"10.1096\/fj.08-122192","article-title":"Functional implications of the influence of ABCA1 on lipid microenvironment at the plasma membrane: a biophysical study","volume":"23","author":"A Zarubica","year":"2009","journal-title":"FASEB J"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"3190","DOI":"10.1111\/j.1742-4658.2011.08170.x","article-title":"Function and regulation of ABCA1-membrane meso-domain organization and reorganization","volume":"278","author":"K Nagao","year":"2011","journal-title":"Febs J"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"2043","DOI":"10.1194\/jlr.M016196","article-title":"Membrane microdomains modulate oligomeric ABCA1 function: impact on apoAI-mediated lipid removal and phosphatidylcholine biosynthesis","volume":"52","author":"I Iatan","year":"2011","journal-title":"J Lipid Res"},{"key":"ref57","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/S0092-8674(04)00167-9","article-title":"Nanoscale organization of multiple GPI-anchored proteins in living cell membranes","volume":"116","author":"P Sharma","year":"2004","journal-title":"Cell"},{"key":"ref58","first-page":"1","article-title":"Transcriptional regulatory networks in lipid metabolism control ABCA1 expression","volume":"1735","author":"G Schmitz","year":"2005","journal-title":"Biochem Biophys Acta"},{"key":"ref59","doi-asserted-by":"crossref","first-page":"12097","DOI":"10.1073\/pnas.200367697","article-title":"Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXR alpha","volume":"97","author":"A Venkateswaran","year":"2000","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref60","doi-asserted-by":"crossref","first-page":"438","DOI":"10.2119\/molmed.2010.00004","article-title":"ATP-binding membrane cassette transporter A1 (ABCA1): a possible link between inflammation and reverse cholesterol transport","volume":"16","author":"K Yin","year":"2010","journal-title":"Mol Med"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1194\/jlr.M300529-JLR200","article-title":"ABCA1-dependent lipid efflux to apolipoprotein A-I mediates HDL particle formation and decreases VLDL secretion from murine hepatocytes","volume":"45","author":"D Sahoo","year":"2004","journal-title":"J Lipid Res"},{"key":"ref62","doi-asserted-by":"crossref","first-page":"10579","DOI":"10.1128\/JVI.00941-06","article-title":"Viral and cellular determinants of the hepatitis C virus envelope-heparan sulfate interaction","volume":"80","author":"H Barth","year":"2006","journal-title":"J Virol"},{"key":"ref63","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1126\/science.282.5390.938","article-title":"Binding of hepatitis C virus to CD81","volume":"282","author":"P Pileri","year":"1998","journal-title":"Science"},{"key":"ref64","doi-asserted-by":"crossref","first-page":"5017","DOI":"10.1093\/emboj\/cdf529","article-title":"The human scavenger receptor class B type I is a novel candidate receptor for the hepatitis C virus","volume":"21","author":"E Scarselli","year":"2002","journal-title":"EMBO J"},{"key":"ref65","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1038\/nm.2581","article-title":"Identification of the Niemann-Pick C1-like 1 cholesterol absorption receptor as a new hepatitis C virus entry factor","volume":"18","author":"B Sainz Jr","year":"2012","journal-title":"Nature Med"},{"key":"ref66","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1038\/nature05654","article-title":"Claudin-1 is a hepatitis C virus co-receptor required for a late step in entry","volume":"446","author":"MJ Evans","year":"2007","journal-title":"Nature"},{"key":"ref67","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1038\/nature07684","article-title":"Human occludin is a hepatitis C virus entry factor required for infection of mouse cells","volume":"457","author":"A Ploss","year":"2009","journal-title":"Nature"},{"key":"ref68","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1016\/j.tim.2011.03.007","article-title":"Multifaceted roles for lipids in viral infection","volume":"19","author":"NS Heaton","year":"2011","journal-title":"Trends Microbiol"},{"key":"ref69","doi-asserted-by":"crossref","unstructured":"Lopez CA, de Vries AH, Marrink SJ (2011) Molecular Mechanism of Cyclodextrin Mediated Cholesterol Extraction. Plos Comput Biol 7.","DOI":"10.1371\/journal.pcbi.1002020"},{"key":"ref70","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1159\/000107533","article-title":"Methyl-beta-cyclodextrin increases permeability of Caco-2 cell monolayers by displacing specific claudins from cholesterol rich domains associated with tight junctions","volume":"20","author":"D Lambert","year":"2007","journal-title":"Cell Physiol Biochem"},{"key":"ref71","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1007\/s00249-007-0201-z","article-title":"Lipids as modulators of membrane fusion mediated by viral fusion proteins","volume":"36","author":"E Teissier","year":"2007","journal-title":"Eur Bioph J"},{"key":"ref72","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1194\/jlr.D008888","article-title":"Huh-7 or HepG2 cells: which is the better model for studying human apolipoprotein-B100 assembly and secretion?","volume":"52","author":"SJ Meex","year":"2011","journal-title":"J Lipid Res"},{"key":"ref73","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.virol.2008.12.031","article-title":"HIV entry in macrophages is dependent on intact lipid rafts","volume":"386","author":"GC Carter","year":"2009","journal-title":"Virology"},{"key":"ref74","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1194\/jlr.M023119","article-title":"HIV-1 Nef mobilizes lipid rafts in macrophages through a pathway that competes with ABCA1-dependent cholesterol efflux","volume":"53","author":"HL Cui","year":"2012","journal-title":"J Lipid Res"},{"key":"ref75","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1124\/mol.110.065029","article-title":"Stimulation of the liver X receptor pathway inhibits HIV-1 replication via induction of ATP-binding cassette transporter A1","volume":"78","author":"MP Morrow","year":"2010","journal-title":"Mol Pharmacol"},{"key":"ref76","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1194\/jlr.M800376-JLR200","article-title":"Synthetic LXR agonist attenuates plaque formation in apoE\u2212\/\u2212 mice without inducing liver steatosis and hypertriglyceridemia","volume":"50","author":"A Kratzer","year":"2009","journal-title":"J Lipid Res"},{"key":"ref77","doi-asserted-by":"crossref","first-page":"1792","DOI":"10.1111\/j.1476-5381.2011.01202.x","article-title":"A novel potent synthetic steroidal liver X receptor agonist lowers plasma cholesterol and triglycerides and reduces atherosclerosis in LDLR(\u2212\/\u2212) mice","volume":"162","author":"D Peng","year":"2011","journal-title":"Br J Pharmacol"},{"key":"ref78","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1016\/j.celrep.2012.08.011","article-title":"Anticancer Activity of the Cholesterol Exporter ABCA1 Gene","volume":"2","author":"B Smith","year":"2012","journal-title":"Cell Reports"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0092140","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,30]],"date-time":"2022-03-30T11:34:49Z","timestamp":1648640089000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0092140"}},"subtitle":[],"editor":[{"given":"Jean-Pierre","family":"Vartanian","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2014,3,19]]},"references-count":78,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2014,3,19]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0092140","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,3,19]]}}}