{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T14:01:03Z","timestamp":1773324063878,"version":"3.50.1"},"reference-count":36,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2014,4,2]],"date-time":"2014-04-02T00:00:00Z","timestamp":1396396800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0092881","type":"journal-article","created":{"date-parts":[[2014,4,2]],"date-time":"2014-04-02T19:01:20Z","timestamp":1396465280000},"page":"e92881","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":10,"title":["Estimated Glomerular Filtration Rate Decline Is a Better Risk Factor for Outcomes of Systemic Disease-Related Nephropathy than for Outcomes of Primary Renal Diseases"],"prefix":"10.1371","volume":"9","author":[{"given":"Shuo-Chun","family":"Weng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Der-Cherng","family":"Tarng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chyong-Mei","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chi-Hung","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming-Ju","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheng-Hsu","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tung-Min","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kuo-Hsiung","family":"Shu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"on behalf of the CKDBHPDH investigators","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2014,4,2]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1210\/jc.2011-2658","article-title":"Metabolic syndrome and insulin resistance as risk factors for development of chronic kidney disease and rapid decline in renal function in elderly","volume":"97","author":"HT Cheng","year":"2012","journal-title":"J Clin Endocrinol Metab"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1038\/ki.2012.276","article-title":"Greater variability in kidney function is associated with an increased risk of death","volume":"82","author":"Z Al-Aly","year":"2012","journal-title":"Kidney Int"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1053\/j.ajkd.2013.01.019","article-title":"Racial differences in estimated GFR decline, ESRD, and mortality in an integrated health system","volume":"62","author":"SF Derose","year":"2013","journal-title":"Am J Kidney Dis"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1053\/j.ajkd.2013.01.012","article-title":"Trajectories of kidney function decline in young black and white adults with preserved GFR: results from the Coronary Artery Risk Development in Young Adults (CARDIA) study","volume":"62","author":"CA Peralta","year":"2013","journal-title":"Am J Kidney Dis"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1046\/j.1523-1755.2002.00092.x","article-title":"Diurnal variations of glomerular filtration rate and albuminuria in diabetic nephropathy","volume":"61","author":"HP Hansen","year":"2002","journal-title":"Kidney Int"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.1038\/ki.2012.281","article-title":"Variability in estimated glomerular filtration rate is an independent risk factor for death among patients with stage 3 chronic kidney disease","volume":"82","author":"RM Perkins","year":"2012","journal-title":"Kidney Int"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.diabres.2010.01.012","article-title":"Microinflammation is a common risk factor for progression of nephropathy and atherosclerosis in Japanese patients with type 2 diabetes","volume":"88","author":"N Kajitani","year":"2010","journal-title":"Diabetes Res Clin Pract"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1111\/jdi.12050","article-title":"Microinflammation in the pathogenesis of diabetic nephropathy","volume":"4","author":"H Shikata K Makino","year":"2013","journal-title":"J Diabetes Investig"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1111\/j.1471-0528.1992.tb13726.x","article-title":"The effect of intrauterine growth retardation on the development of renal nephrons","volume":"99","author":"SA Hinchliffe","year":"1992","journal-title":"Br J Obstet Gynaecol"},{"key":"ref10","unstructured":"Jocelyn W, Sanjeevkumar RP (2009) Changes in Kidney Function. Hazzard\u2019s geriatric medicine and gerontology. 6th ed. Seattle, USA: McGraw-Hill; p.1009\u20131015."},{"key":"ref11","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1111\/j.1523-1755.2004.00837.x","article-title":"Epidemiologic data of renal diseases from a single unit in China: analysis based on 13,519 renal biopsies","volume":"66","author":"LS Li","year":"2004","journal-title":"Kidney Int"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1161\/01.HYP.26.6.869","article-title":"Diabetes mellitus and associated hypertension, vascular disease, and nephropathy. An update","volume":"26","author":"JR Sowers","year":"1995","journal-title":"Hypertension"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1097\/00000441-200209000-00004","article-title":"Primary renal disease as a cardiovascular risk factor","volume":"324","author":"ED Crook","year":"2002","journal-title":"Am J Med Sci"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1038\/ki.2011.404","article-title":"Glomerular hyperfiltration and increased glomerular filtration surface are associated with renal function decline in normo- and microalbuminuric type 2 diabetes","volume":"81","author":"T Moriya","year":"2012","journal-title":"Kidney Int"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1093\/ndt\/13.3.651","article-title":"The effect of metabolic control on rate of decline in renal function in insulin-dependent diabetes mellitus with overt diabetic nephropathy","volume":"13","author":"H Mulec","year":"1998","journal-title":"Nephrol Dial Transplant"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1038\/ki.2010.525","article-title":"Persistent proteinuria and dyslipidemia increase the risk of progressive chronic kidney disease in lupus erythematosus","volume":"79","author":"HN Reich","year":"2011","journal-title":"Kidney Int"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.2215\/CJN.04500511","article-title":"Clinical outcomes and predictors for ESRD and mortality in primary GN","volume":"7","author":"YH Chou","year":"2012","journal-title":"Clin J Am Soc Nephrol"},{"key":"ref18","first-page":"270","article-title":"Renal manifestations of systemic diseases","volume":"18","author":"SP Andreoli","year":"1998","journal-title":"Semin Nephrol"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1038\/ki.2012.418","article-title":"Prediction of renal endpoints in chronic kidney disease","volume":"83","author":"Z Al-Aly","year":"2013","journal-title":"Kidney Int"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1038\/ki.2010.129","article-title":"Daily oral sodium bicarbonate preserves glomerular filtration rate by slowing its decline in early hypertensive nephropathy","volume":"78","author":"A Mahajan","year":"2010","journal-title":"Kidney Int"},{"key":"ref21","unstructured":"Estimation of GFR. KDOQI Clinical Practice Guidelines for Chronic Kidney Disease: Evaluation, Classification, and Stratification (Guideline 4). National Kidney Foundation, Inc. <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.kidney.org\/professionals\/kdoqi\/guidelines_ckd\/p5_lab_g4.htm\" xlink:type=\"simple\">http:\/\/www.kidney.org\/professionals\/kdoqi\/guidelines_ckd\/p5_lab_g4.htm<\/ext-link><underline>.<\/underline> Accessed 2002."},{"key":"ref22","first-page":"S4","article-title":"Risk factors for ESRD in individuals with preserved estimated GFR with and without albuminuria: results from the Kidney Early Evaluation Program (KEEP) Am J Kidney Dis","volume":"61(4","author":"TI Chang","year":"2013"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1053\/j.ajkd.2006.10.007","article-title":"Epidemiological features of CKD in Taiwan","volume":"49","author":"HW Kuo","year":"2007","journal-title":"Am J Kidney Dis"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"S131","DOI":"10.1097\/01.ASN.0000070152.11927.4A","article-title":"Prevalence of kidney damage in Australian adults: The AusDiab kidney study","volume":"14(7","author":"SJ Chadban","year":"2003","journal-title":"J Am Soc Nephrol"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"2349","DOI":"10.1001\/jama.2012.16817","article-title":"Age and association of kidney measures with mortality and end-stage renal disease","volume":"308","author":"SI Hallan","year":"2012","journal-title":"JAMA"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/S0140-6736(13)60595-4","article-title":"Chronic kidney disease and cardiovascular risk: epidemiology, mechanisms, and prevention","volume":"382","author":"RT Gansevoort","year":"2013","journal-title":"Lancet"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"1649","DOI":"10.1016\/S0140-6736(12)61272-0","article-title":"Associations of kidney disease measures with mortality and end-stage renal disease in individuals with and without hypertension: a meta-analysis","volume":"380","author":"BK Mahmoodi","year":"2012","journal-title":"Lancet"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"f324","DOI":"10.1136\/bmj.f324","article-title":"Associations of estimated glomerular filtration rate and albuminuria with mortality and renal failure by sex: a meta-analysis","volume":"346","author":"D Nitsch","year":"2013","journal-title":"BMJ"},{"key":"ref29","doi-asserted-by":"crossref","unstructured":"Hsu TW, Liu JS, Hung SC, Kuo KL, Chang YK, et al. (2013) Renoprotective Effect of Renin-Angiotensin-Aldosterone System Blockade in Patients With Predialysis Advanced Chronic Kidney Disease, Hypertension, and Anemia. JAMA Intern Med Dec 16. doi:<ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/dx.doi.org\/10.1001\/jamainternmed.2013.12700\" xlink:type=\"simple\">10.1001\/jamainternmed.2013.12700<\/ext-link> [Epub ahead of print].","DOI":"10.1001\/jamainternmed.2013.12700"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1053\/j.ajkd.2010.01.024","article-title":"Is high serum uric acid a risk marker or a target for treatment? Examination of its independent effect in a large cohort with low cardiovascular risk","volume":"56","author":"CP Wen","year":"2010","journal-title":"Am J Kidney Dis"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1093\/aje\/kwi187","article-title":"When is baseline adjustment useful in analyses of change? An example with education and cognitive change","volume":"162","author":"MM Glymour","year":"2005","journal-title":"Am J Epidemiol"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"3977","DOI":"10.1093\/ndt\/gfn406","article-title":"Incidence, prevalence and mortality trends of dialysis end-stage renal disease in Taiwan from 1990 to 2001: the impact of national health insurance","volume":"23","author":"WC Yang","year":"2008","journal-title":"Nephrol Dial Transplant"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"c109","DOI":"10.1159\/000145453","article-title":"Outcomes of stage 3\u20135 chronic kidney disease before end-stage renal disease at a single center in Taiwan","volume":"109","author":"YL Chiu","year":"2008","journal-title":"Nephron Clin Pract"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"3426","DOI":"10.1093\/ndt\/gfp259","article-title":"Multidisciplinary predialysis education decreases the incidence of dialysis and reduces mortality\u2013a controlled cohort study based on the NKF\/DOQI guidelines","volume":"24","author":"IW Wu","year":"2009","journal-title":"Nephrol Dial Transplant"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1093\/ndt\/gfs469","article-title":"Effectiveness of multidisciplinary care for chronic kidney disease in Taiwan: a 3-year prospective cohort study","volume":"28","author":"YR Chen","year":"2013","journal-title":"Nephrol Dial Transplant"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"3277","DOI":"10.1093\/ndt\/gfp448","article-title":"We don\u2019t need no education \u2026. (Pink Floyd, The Wall) Multidisciplinary predialysis education programmes: pass or fail","volume":"24","author":"W Van Biesen","year":"2009","journal-title":"Nephrol Dial Transplant"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0092881","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,10,23]],"date-time":"2018-10-23T20:27:08Z","timestamp":1540326428000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0092881"}},"subtitle":[],"editor":[{"given":"Valquiria","family":"Bueno","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2014,4,2]]},"references-count":36,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2014,4,2]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0092881","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,4,2]]}}}