{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T13:19:17Z","timestamp":1775308757541,"version":"3.50.1"},"reference-count":25,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2014,4,7]],"date-time":"2014-04-07T00:00:00Z","timestamp":1396828800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0093902","type":"journal-article","created":{"date-parts":[[2014,4,7]],"date-time":"2014-04-07T21:56:15Z","timestamp":1396907775000},"page":"e93902","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":16,"title":["APOA-I: A Possible Novel Biomarker for Metabolic Side Effects in First Episode Schizophrenia"],"prefix":"10.1371","volume":"9","author":[{"given":"Xueqin","family":"Song","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xue","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinsong","family":"Gao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingping","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Youhui","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoduo","family":"Fan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luxian","family":"Lv","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2014,4,7]]},"reference":[{"key":"ref1","first-page":"CD008016","article-title":"Maintenance treatment with antipsychotic drugs for schizophrenia","volume":"5","author":"S Leucht","year":"2012","journal-title":"Cochrane Database Syst Rev"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"425","DOI":"10.4088\/JCP.v63n0509","article-title":"A retrospective comparison of weight, lipid, and glucose changes between risperidone- and olanzapine-treated inpatients: metabolic outcomes after 1 year","volume":"63","author":"JM Meyer","year":"2002","journal-title":"J Clin Psychiatry"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"e1002016","DOI":"10.1371\/journal.pcbi.1002016","article-title":"Exploring off-targets and off-systems for adverse drug reactions via chemical-protein interactome\u2014clozapine-induced agranulocytosis as a case study","volume":"7","author":"L Yang","year":"2011","journal-title":"PLoS Comput Biol"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.2165\/11596300-000000000-00000","article-title":"Atypical antipsychotic-induced weight gain: insights into mechanisms of action","volume":"25","author":"JL Roerig","year":"2011","journal-title":"CNS Drugs"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.schres.2006.02.016","article-title":"Protein expression profiling of postmortem brain in schizophrenia","volume":"84","author":"J Mei","year":"2006","journal-title":"Schizophr Res"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1002\/prca.201200044","article-title":"Proteome-base biomarkers in diabetes mellitus: progress on biofluids&apos; protein profiling using mass spectrometry","volume":"6","author":"A Isabel Padrao","year":"2012","journal-title":"Proteomics Clin Appl"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"2808","DOI":"10.1002\/pmic.201100586","article-title":"Proteomic profiling of high glucose primed monocytes identifies cyclophilin A as a potential secretory marker of inflammation in type 2 diabetes","volume":"12","author":"S Ramachandran","year":"2012","journal-title":"Proteomics"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"e47996","DOI":"10.1371\/journal.pone.0047996","article-title":"Activity-based protein profiling reveals mitochondrial oxidative enzyme impairment and restoration in diet-induced obese mice","volume":"7","author":"NC Sadler","year":"2012","journal-title":"PLoS One"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1093\/bfgp\/elm009","article-title":"The use of ASB-14 in combination with CHAPS is the best for solubilization of human brain proteins for two-dimensional gel electrophoresis","volume":"6","author":"D Martins-de-Souza","year":"2007","journal-title":"Brief Funct Genomic Proteomic"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"3666","DOI":"10.1002\/1522-2683(200011)21:17<3666::AID-ELPS3666>3.0.CO;2-6","article-title":"A modified silver staining protocol for visualization of proteins compatible with matrix-assisted laser desorption\/ionization and electrospray ionization-mass spectrometry","volume":"21","author":"JX Yan","year":"2000","journal-title":"Electrophoresis"},{"key":"ref11","first-page":"350","article-title":"Tetranectin and apolipoprotein A-I in cerebrospinal fluid as potential biomarkers for Parkinson&apos;s disease","volume":"122","author":"ES Wang","year":"2010","journal-title":"Acta Neurol Scand"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.atherosclerosis.2005.06.043","article-title":"SNPs at the APOA5 gene account for the strong association with hypertriglyceridaemia at the APOA5\/A4\/C3\/A1 locus on chromosome 11q23 in the Northern Irish population","volume":"185","author":"WT Wright","year":"2006","journal-title":"Atherosclerosis"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1016\/S0888-7543(05)80124-7","article-title":"Structure and linkage of the D2 dopamine receptor and neural cell adhesion molecule genes on human chromosome 11q23","volume":"14","author":"JH Eubanks","year":"1992","journal-title":"Genomics"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1007\/s00702-006-0607-2","article-title":"Decreased levels of apolipoprotein A-I in plasma of schizophrenic patients","volume":"114","author":"YJ La","year":"2007","journal-title":"J Neural Transm"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"1118","DOI":"10.1038\/sj.mp.4002108","article-title":"Independent protein-profiling studies show a decrease in apolipoprotein A1 levels in schizophrenia CSF, brain and peripheral tissues","volume":"13","author":"JT Huang","year":"2008","journal-title":"Mol Psychiatry"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"719","DOI":"10.3109\/15622971003758748","article-title":"Different apolipoprotein E, apolipoprotein A1 and prostaglandin-H2 D-isomerase levels in cerebrospinal fluid of schizophrenia patients and healthy controls","volume":"11","author":"D Martins-De-Souza","year":"2010","journal-title":"World J Biol Psychiatry"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1139\/o03-081","article-title":"Effects of ethanol and haloperidol on plasma levels of hepatic enzymes, lipid profile, and apolipoprotein in rats","volume":"82","author":"SM Vasconcelos","year":"2004","journal-title":"Biochem Cell Biol"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1124\/jpet.112.199257","article-title":"Anti-inflammatory functions of apolipoprotein A-I and high-density lipoprotein are preserved in trimeric apolipoprotein A-I","volume":"344","author":"AJ Murphy","year":"2013","journal-title":"J Pharmacol Exp Ther"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1111\/j.1365-2354.2008.00965.x","article-title":"Characterization of apolipoprotein A-I as a potential biomarker for cholangiocarcinoma","volume":"18","author":"X Wang","year":"2009","journal-title":"Eur J Cancer Care (Engl)"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"8588","DOI":"10.1074\/jbc.270.15.8588","article-title":"Role of apolipoprotein A-I in cholesterol transfer between lipoproteins. Evidence for involvement of specific apoA-I domains","volume":"270","author":"QH Meng","year":"1995","journal-title":"J Biol Chem"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1002\/pmic.200500257","article-title":"Proteome analysis of hepatocellular carcinoma by laser capture microdissection","volume":"6","author":"J Ai","year":"2006","journal-title":"Proteomics"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1530\/eje.1.02275","article-title":"The CC genotype of the GNAS T393C polymorphism is associated with obesity and insulin resistance in women with polycystic ovary syndrome","volume":"155","author":"S Hahn","year":"2006","journal-title":"Eur J Endocrinol"},{"key":"ref23","first-page":"1053","article-title":"Increased expression of Gs(alpha) enhances activation of the adenylyl cyclase signal transduction cascade","volume":"11","author":"X Yang","year":"1997","journal-title":"Mol Endocrinol"},{"key":"ref24","first-page":"748","article-title":"In vitro effect of adenosine A2A receptor antagonist SCH 442416 on the expression of glutamine synthetase and glutamate aspartate transporter in rat retinal Muller cells at elevated hydrostatic pressure","volume":"27","author":"J Yu","year":"2012","journal-title":"Oncol Rep"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.schres.2007.12.487","article-title":"Change in metabolic syndrome parameters with antipsychotic treatment in the CATIE Schizophrenia Trial: prospective data from phase 1","volume":"101","author":"JM Meyer","year":"2008","journal-title":"Schizophr Res"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0093902","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,9]],"date-time":"2020-05-09T01:59:02Z","timestamp":1588989542000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0093902"}},"subtitle":[],"editor":[{"given":"Jason","family":"Mulvenna","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2014,4,7]]},"references-count":25,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2014,4,7]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0093902","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,4,7]]}}}