{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T02:11:43Z","timestamp":1791252703146,"version":"4.1.0"},"reference-count":28,"publisher":"Public Library of Science (PLoS)","issue":"5","license":[{"start":{"date-parts":[[2014,5,9]],"date-time":"2014-05-09T00:00:00Z","timestamp":1399593600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0095144","type":"journal-article","created":{"date-parts":[[2014,5,9]],"date-time":"2014-05-09T17:05:36Z","timestamp":1399655136000},"page":"e95144","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":55,"title":["Skeletal Development of Mice Lacking Bone Sialoprotein (BSP) - Impairment of Long Bone Growth and Progressive Establishment of High Trabecular Bone Mass"],"prefix":"10.1371","volume":"9","author":[{"given":"Wafa","family":"Bouleftour","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maya","family":"Boudiffa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ndeye Mari\u00e8me","family":"Wade-Gueye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gu\u00e9na\u00eblle","family":"Bou\u00ebt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Cardelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norbert","family":"Laroche","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arnaud","family":"Vanden-Bossche","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mireille","family":"Thomas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edith","family":"Bonnelye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jane E.","family":"Aubin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurence","family":"Vico","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie H\u00e9l\u00e8ne","family":"Lafage-Proust","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luc","family":"Malaval","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2014,5,9]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1080\/03008200390152061","article-title":"Six genes expressed in bones and teeth encode the current members of the SIBLING family of proteins","volume":"44","author":"LW Fisher","year":"2003","journal-title":"Connect Tissue Res"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1177\/10454411990100010401","article-title":"Bone sialoprotein","volume":"10","author":"B Ganss","year":"1999","journal-title":"Crit Rev Oral Biol Med"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1177\/10454411000110030101","article-title":"Osteopontin","volume":"11","author":"J Sodek","year":"2000","journal-title":"Crit Rev Oral Biol Med"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"25455","DOI":"10.1074\/jbc.M312408200","article-title":"Extracellular bone acidic glycoprotein-75 defines condensed mesenchyme regions to be mineralized and localizes with bone sialoprotein during intramembranous bone formation","volume":"279","author":"JP Gorski","year":"2004","journal-title":"J Biol Chem"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1002\/jbmr.5650070816","article-title":"Developmental expression of bone sialoprotein mRNA in rat mineralized connective tissues","volume":"7","author":"J Chen","year":"1992","journal-title":"J Bone Miner Res"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1084\/jem.20071294","article-title":"Bone sialoprotein plays a functional role in bone formation and osteoclastogenesis","volume":"205","author":"L Malaval","year":"2008","journal-title":"J Exp Med"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"2393","DOI":"10.1002\/jbmr.245","article-title":"Bone sialoprotein deficiency impairs osteoclastogenesis and mineral resorption in vitro","volume":"25","author":"M Boudiffa","year":"2010","journal-title":"J Bone Min Res"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"8424","DOI":"10.1073\/pnas.90.18.8424","article-title":"Derivation of completely cell culture-derived mice from early-passage embryonic stem cells","volume":"90","author":"A Nagy","year":"1993","journal-title":"Proc Natl Acad Sci U A"},{"key":"ref9","doi-asserted-by":"crossref","unstructured":"St-Jacques B, Hammerschmidt M, McMahon AP (1999) Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation. Genes Dev 13: 2072\u20132086. Available: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/genesdev.cshlp.org\/content\/13\/16\/2072.short\" xlink:type=\"simple\">http:\/\/genesdev.cshlp.org\/content\/13\/16\/2072.short<\/ext-link>. Accessed 22 May 2013.","DOI":"10.1101\/gad.13.16.2072"},{"key":"ref10","doi-asserted-by":"crossref","unstructured":"David V, Laroche N, Boudignon B, Lafage-Proust M-H, Alexandre C, et al. (2003) Noninvasive in vivo monitoring of bone architecture alterations in hindlimb-unloaded female rats using novel three-dimensional microcomputed tomography. J Bone Miner Res 18: 1622\u20131631. Available: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1359\/jbmr.2003.18.9.1622\/full\" xlink:type=\"simple\">http:\/\/onlinelibrary.wiley.com\/doi\/10.1359\/jbmr.2003.18.9.1622\/full<\/ext-link>. Accessed 22 May 2013.","DOI":"10.1359\/jbmr.2003.18.9.1622"},{"key":"ref11","first-page":"25","article-title":"Home improvement: C57BL\/6J mice given more naturalistic nesting materials build better nests","volume":"47","author":"SE Hess","year":"2008","journal-title":"J Am Assoc Lab Anim Sci JAALAS"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"537","DOI":"10.7150\/ijbs.6.537","article-title":"Circling behavior developed in Dmp1 null mice is due to bone defects in the vestibular apparatus","volume":"6","author":"K Lv","year":"2010","journal-title":"Int J Biol Sci"},{"key":"ref13","doi-asserted-by":"crossref","unstructured":"Sauce B, de Brito RA, Peripato AC (2012) Genetic architecture of nest building in mice LG\/J \u00d7 SM\/J. Front Genet Archit 3: 90. Available: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.frontiersin.org\/Genetic_Architecture\/10.3389\/fgene.2012.00090\/abstract\" xlink:type=\"simple\">http:\/\/www.frontiersin.org\/Genetic_Architecture\/10.3389\/fgene.2012.00090\/abstract<\/ext-link>. Accessed 26 August 2013.","DOI":"10.3389\/fgene.2012.00090"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1186\/1471-2202-14-37","article-title":"Improving basic and translational science by accounting for litter-to-litter variation in animal models","volume":"14","author":"SE Lazic","year":"2013","journal-title":"BMC Neurosci"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1093\/jmicro\/51.6.413","article-title":"Effects of enamel matrix derivative on mineralized tissue formation during bone wound healing in rat parietal bone defects","volume":"51","author":"Y Sawae","year":"2002","journal-title":"J Electron Microsc Tokyo"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1161\/01.RES.86.8.885","article-title":"Bone sialoprotein mediates human endothelial cell attachment and migration and promotes angiogenesis","volume":"86","author":"A Bellahcene","year":"2000","journal-title":"Circ Res"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1042\/bj3020175","article-title":"Modulation of crystal formation by bone phosphoproteins: role of glutamic acid-rich sequences in the nucleation of hydroxyapatite by bone sialoprotein","volume":"1)","author":"GK Hunter","year":"1994","journal-title":"Biochem J 302 (Pt"},{"key":"ref18","doi-asserted-by":"crossref","unstructured":"Weizmann S, Tong A, Reich A, Genina O, Yayon A, et al. (2005) FGF upregulates osteopontin in epiphyseal growth plate chondrocytes: implications for endochondral ossification. Matrix Biol 24: 520\u2013529. Available: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0945053X05000995\" xlink:type=\"simple\">http:\/\/www.sciencedirect.com\/science\/article\/pii\/S0945053X05000995<\/ext-link>. Accessed 22 May 2013.","DOI":"10.1016\/j.matbio.2005.07.003"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1038\/nature01657","article-title":"Developmental regulation of the growth plate","volume":"423","author":"HM Kronenberg","year":"2003","journal-title":"Nature"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"2543","DOI":"10.1002\/jbmr.234","article-title":"IGF-1 and bone: New discoveries from mouse models","volume":"25","author":"S Yakar","year":"2010","journal-title":"J Bone Miner Res Off J Am Soc Bone Miner Res"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1172\/JCI0215463","article-title":"Circulating levels of IGF-1 directly regulate bone growth and density","volume":"110","author":"S Yakar","year":"2002","journal-title":"J Clin Invest"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.ydbio.2006.06.042","article-title":"Independent regulation of skeletal growth by IHH and IGF signaling","volume":"298","author":"F Long","year":"2006","journal-title":"Dev Biol"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1002\/cbf.2841","article-title":"The chicken or the egg: PHEX, FGF23 and SIBLINGs unscrambled","volume":"30","author":"PSN Rowe","year":"2012","journal-title":"Cell Biochem Funct"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1016\/j.bone.2012.06.022","article-title":"MEPE is a novel regulator of growth plate cartilage mineralization","volume":"51","author":"KA Staines","year":"2012","journal-title":"Bone"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"5103","DOI":"10.1210\/en.2010-0091","article-title":"Mice lacking bone sialoprotein (BSP) lose bone after ovariectomy and display skeletal site-specific response to intermittent PTH treatment","volume":"151","author":"NM Wade-Gueye","year":"2010","journal-title":"Endocrinology"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1007\/s00223-001-1121-z","article-title":"Osteopontin deficiency increases mineral content and mineral crystallinity in mouse bone","volume":"71","author":"AL Boskey","year":"2002","journal-title":"Calcif Tissue Int"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1359\/jbmr.060619","article-title":"Elevated skeletal osteopontin levels contribute to the hypophosphatasia phenotype in Akp2(\u2212\/\u2212) mice","volume":"21","author":"D Harmey","year":"2006","journal-title":"J Bone Min Res"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1016\/j.bone.2009.06.005","article-title":"Absence of bone sialoprotein (BSP) impairs cortical defect repair in mouse long bone","volume":"45","author":"L Malaval","year":"2009","journal-title":"Bone"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0095144","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,10,22]],"date-time":"2018-10-22T13:10:04Z","timestamp":1540213804000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0095144"}},"subtitle":[],"editor":[{"given":"Jean-Marc","family":"Vanacker","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2014,5,9]]},"references-count":28,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2014,5,9]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0095144","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,5,9]]}}}