{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,26]],"date-time":"2026-07-26T00:04:44Z","timestamp":1785024284510,"version":"3.55.0"},"reference-count":53,"publisher":"Public Library of Science (PLoS)","issue":"6","license":[{"start":{"date-parts":[[2014,6,10]],"date-time":"2014-06-10T00:00:00Z","timestamp":1402358400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0099160","type":"journal-article","created":{"date-parts":[[2014,6,10]],"date-time":"2014-06-10T23:59:05Z","timestamp":1402444745000},"page":"e99160","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":22,"title":["Source-Identifying Biomarker Ions between Environmental and Clinical Burkholderia pseudomallei Using Whole-Cell Matrix-Assisted Laser Desorption\/Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS)"],"prefix":"10.1371","volume":"9","author":[{"given":"Suthamat","family":"Niyompanich","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janthima","family":"Jaresitthikunchai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kitima","family":"Srisanga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sittiruk","family":"Roytrakul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sumalee","family":"Tungpradabkul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2014,6,10]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1128\/CMR.18.2.383-416.2005","article-title":"Melioidosis: epidemiology, pathophysiology, and management","volume":"18","author":"AC Cheng","year":"2005","journal-title":"Clinical microbiology reviews"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1056\/NEJMra1204699","article-title":"Melioidosis","volume":"367","author":"WJ Wiersinga","year":"2012","journal-title":"The New England journal of medicine"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1146\/annurev.micro.112408.134030","article-title":"Molecular insights into Burkholderia pseudomallei and Burkholderia mallei pathogenesis","volume":"64","author":"EE Galyov","year":"2010","journal-title":"Annual review of microbiology"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1038\/nrmicro1385","article-title":"Melioidosis: insights into the pathogenicity of Burkholderia pseudomallei","volume":"4","author":"WJ Wiersinga","year":"2006","journal-title":"Nature reviews Microbiology"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/S0924-8579(00)00334-4","article-title":"Antibiotic susceptibility of Burkholderia pseudomallei from tropical northern Australia and implications for therapy of melioidosis","volume":"17","author":"AW Jenney","year":"2001","journal-title":"International journal of antimicrobial agents"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"458","DOI":"10.4269\/ajtmh.1999.60.458","article-title":"Epidemiology of Burkholderia pseudomallei in Thailand","volume":"60","author":"V Vuddhakul","year":"1999","journal-title":"The American journal of tropical medicine and hygiene"},{"key":"ref7","first-page":"756","article-title":"Epidemiology of arabinose assimilation in Burkholderia pseudomallei isolated from patients and soil in Thailand","volume":"30","author":"S Trakulsomboon","year":"1999","journal-title":"The Southeast Asian journal of tropical medicine and public health"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1128\/AEM.01822-10","article-title":"Randomized soil survey of the distribution of Burkholderia pseudomallei in rice fields in Laos","volume":"77","author":"S Rattanavong","year":"2011","journal-title":"Applied and environmental microbiology"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"1432","DOI":"10.1128\/JCM.01720-09","article-title":"Distribution of melioidosis cases and viable Burkholderia pseudomallei in soil: evidence for emerging melioidosis in Taiwan","volume":"48","author":"Y-S Chen","year":"2010","journal-title":"Journal of clinical microbiology"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1016\/S1286-4579(01)01417-4","article-title":"Burkholderia pseudomallei virulence: definition, stability and association with clonality","volume":"3","author":"GC Ulett","year":"2001","journal-title":"Microbes and infection\/Institut Pasteur"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"1687","DOI":"10.1128\/JCM.33.7.1687-1690.1995","article-title":"Subdivision of Burkholderia pseudomallei ribotypes into multiple types by random amplified polymorphic DNA analysis provides new insights into epidemiology","volume":"33","author":"A Haase","year":"1995","journal-title":"Journal of clinical microbiology"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1099\/00222615-46-7-557","article-title":"Toxin production by Burkholderia pseudomallei strains and correlation with severity of melioidosis","volume":"46","author":"A Haase","year":"1997","journal-title":"Journal of Medical Microbiology"},{"key":"ref13","first-page":"160","article-title":"Enzymatic profiling of clinical and environmental isolates of Burkholderia pseudomallei","volume":"29","author":"SM Liew","year":"2012","journal-title":"Tropical biomedicine"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/S0001-706X(01)00176-0","article-title":"Ribotyping of Burkholderia pseudomallei from clinical and soil isolates in Thailand","volume":"80","author":"RW Sermswan","year":"2001","journal-title":"Acta Tropica"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"56","DOI":"10.3201\/eid0601.000110","article-title":"Burkholderia pseudomallei traced to water treatment plant in Australia","volume":"6","author":"TJ Inglis","year":"2000","journal-title":"Emerging infectious diseases"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1099\/00222615-47-8-689","article-title":"Flagellin gene variation between clinical and environmental isolates of Burkholderia pseudomallei contrasts with the invariance among clinical isolates","volume":"47","author":"C Winstanley","year":"1998","journal-title":"Journal of medical microbiology"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/S0001-706X(00)00137-6","article-title":"Genotype analysis of Burkholderia pseudomallei using randomly amplified polymorphic DNA (RAPD): indicative of genetic differences amongst environmental and clinical isolates","volume":"77","author":"C Leelayuwat","year":"2000","journal-title":"Acta tropica"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/S0928-8244(97)00104-1","article-title":"Characterisation and molecular typing of Burkholderia pseudomallei: are disease presentations of melioidosis clonally related?","volume":"20","author":"R Norton","year":"1998","journal-title":"FEMS immunology and medical microbiology"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"5477","DOI":"10.1128\/JCM.42.12.5477-5483.2004","article-title":"Isolates of Burkholderia pseudomallei from Northern Australia are distinct by multilocus sequence typing, but strain types do not correlate with clinical presentation","volume":"42","author":"AC Cheng","year":"2004","journal-title":"Journal of clinical microbiology"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"2553","DOI":"10.1128\/JCM.00629-06","article-title":"Nonrandom distribution of Burkholderia pseudomallei clones in relation to geographical location and virulence","volume":"44","author":"M Vesaratchavest","year":"2006","journal-title":"Journal of clinical microbiology"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"e0037762","DOI":"10.1371\/journal.pone.0037762","article-title":"Genomic islands as a marker to differentiate between clinical and environmental Burkholderia pseudomallei","volume":"7","author":"T Bartpho","year":"2012","journal-title":"PLoS ONE"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1038\/nrmicro2243","article-title":"Mass spectrometry tools for the classification and identification of bacteria","volume":"8","author":"S Sauer","year":"2010","journal-title":"Nature reviews Microbiology"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.syapm.2010.11.013","article-title":"Applications of whole-cell matrix-assisted laser-desorption\/ionization time-of-flight mass spectrometry in systematic microbiology","volume":"34","author":"M Welker","year":"2011","journal-title":"Systematic and applied microbiology"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"1626","DOI":"10.1111\/j.1469-0691.2010.03364.x","article-title":"Matrix-assisted laser desorption ionization time-of-flight mass spectrometry: usefulness for taxonomy and epidemiology","volume":"16","author":"PR Murray","year":"2010","journal-title":"Clinical Microbiology and Infection"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.ijms.2013.04.016","article-title":"Identification of bacteria using mass spectrometry techniques","volume":"353","author":"L Kr\u00e1sn\u00fd","year":"2013","journal-title":"International Journal of Mass Spectrometry"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.clinbiochem.2010.06.017","article-title":"MALDI-TOF mass spectrometry tools for bacterial identification in clinical microbiology laboratory","volume":"44","author":"E Carbonnelle","year":"2011","journal-title":"Clinical Biochemistry"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/j.mimet.2013.01.004","article-title":"Mass spectrometry and tandem mass spectrometry characterization of protein patterns, protein markers and whole proteomes for pathogenic bacteria","volume":"92","author":"J Intelicato-Young","year":"2013","journal-title":"Journal of microbiological methods"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1002\/mas.21359","article-title":"MALDI TOF MS profiling of bacteria at the strain level: a review","volume":"32","author":"TR Sandrin","year":"2013","journal-title":"Mass spectrometry reviews"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.ijmm.2010.06.002","article-title":"MALDI-TOF MS fingerprinting allows for discrimination of major methicillin-resistant Staphylococcus aureus lineages","volume":"301","author":"M Wolters","year":"2011","journal-title":"International journal of medical microbiology: IJMM"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1016\/j.mimet.2006.10.012","article-title":"Discrimination and characterization of environmental strains of Escherichia coli by matrix-assisted laser desorption\/ionization time-of-flight mass spectrometry (MALDI-TOF-MS)","volume":"68","author":"TJ Siegrist","year":"2007","journal-title":"Journal of microbiological methods"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/j.meegid.2009.01.012","article-title":"High throughput identification of clinical isolates of Staphylococcus aureus using MALDI-TOF-MS of intact cells","volume":"9","author":"L Rajakaruna","year":"2009","journal-title":"Infection, genetics and evolution: journal of molecular epidemiology and evolutionary genetics in infectious diseases"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"7767","DOI":"10.1128\/AEM.01402-08","article-title":"Rapid classification and identification of Salmonellae at the species and subspecies levels by whole-cell matrix-assisted laser desorption ionization-time of flight mass spectrometry","volume":"74","author":"R Dieckmann","year":"2008","journal-title":"Applied and environmental microbiology"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1016\/j.watres.2007.09.005","article-title":"Characterization of environmental isolates of Enterococcus spp. by matrix-assisted laser desorption\/ionization time-of-flight mass spectrometry","volume":"42","author":"RA Giebel","year":"2008","journal-title":"Water research"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"2912","DOI":"10.1128\/JCM.00389-09","article-title":"Matrix-assisted laser desorption ionization-time of flight mass spectrometry for fast and reliable identification of clinical yeast isolates","volume":"47","author":"G Marklein","year":"2009","journal-title":"Journal of Clinical Microbiology"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"4055","DOI":"10.1128\/AEM.02698-09","article-title":"Identification and typing of Lactococcus lactis by matrix-assisted laser desorption ionization-time of flight mass spectrometry","volume":"76","author":"K Tanigawa","year":"2010","journal-title":"Applied and environmental microbiology"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1016\/j.mimet.2005.08.005","article-title":"The development of a matrix-assisted laser desorption\/ionization mass spectrometry-based method for the protein fingerprinting and identification of Aeromonas species using whole cells","volume":"65","author":"MJ Donohue","year":"2006","journal-title":"Journal of microbiological methods"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.micres.2011.09.002","article-title":"Rapid discrimination of environmental Vibrio by matrix-assisted laser desorption ionization time-of-flight mass spectrometry","volume":"167","author":"R Eddabra","year":"2012","journal-title":"Microbiological research"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"e0002843","DOI":"10.1371\/journal.pone.0002843","article-title":"Classification and identification of bacteria by mass spectrometry and computational analysis","volume":"3","author":"S Sauer","year":"2008","journal-title":"PloS one"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1002\/jms.1474","article-title":"Mass spectrometry in biodefense","volume":"43","author":"PA Demirev","year":"2008","journal-title":"Journal of mass spectrometry: JMS"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"225","DOI":"10.3201\/eid0802.010164","article-title":"Public health assessment of potential biological terrorism agents","volume":"8","author":"LD Rotz","year":"2002","journal-title":"Emerging Infectious Diseases"},{"key":"ref41","doi-asserted-by":"crossref","unstructured":"Karger A, Stock R, Ziller M, Elschner MC, Bettin B, <etal>et al<\/etal>.. (2012) Rapid identification of Burkholderia mallei and Burkholderia pseudomallei by intact cell Matrix-assisted Laser Desorption\/Ionisation mass spectrometric typing. BMC Microbiology 12.","DOI":"10.1186\/1471-2180-12-229"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1086\/600885","article-title":"Ongoing revolution in bacteriology: routine identification of bacteria by matrix-assisted laser desorption ionization time-of-flight mass spectrometry","volume":"49","author":"P Seng","year":"2009","journal-title":"Clinical infectious diseases: an official publication of the Infectious Diseases Society of America"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1128\/JB.01258-06","article-title":"Biological relevance of colony morphology and phenotypic switching by Burkholderia pseudomallei","volume":"189","author":"N Chantratita","year":"2007","journal-title":"Journal of bacteriology"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"3142","DOI":"10.1128\/JCM.01349-12","article-title":"Matrix-assisted laser desorption ionization\u2013time of flight mass spectrometry for rapid identification of Burkholderia pseudomallei: importance of expanding databases with pathogens endemic to different localities","volume":"50","author":"SKP Lau","year":"2012","journal-title":"Journal of Clinical Microbiology"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1128\/AEM.71.1.58-64.2005","article-title":"Effect of culture conditions on microorganism identification by matrix-assisted laser desorption ionization mass spectrometry","volume":"71","author":"N Valentine","year":"2005","journal-title":"Applied and Environmental Microbiology"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1017\/S0950268800051736","article-title":"Pseudomonas pseudomallei isolates collected over 25 years from a non-tropical endemic focus show clonality on the basis of ribotyping","volume":"113","author":"B Currie","year":"1994","journal-title":"Epidemiology and infection"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/S0001-706X(99)00066-2","article-title":"Ecology of Burkholderia pseudomallei and the interactions between environmental Burkholderia spp. and human-animal hosts","volume":"74","author":"DA Dance","year":"2000","journal-title":"Acta tropica"},{"key":"ref48","doi-asserted-by":"crossref","unstructured":"Baker A, Mayo M, Owens L, Burgess G, Norton R, <etal>et al<\/etal>.. (2013) Biogeography of Burkholderia pseudomallei in the Torres Strait Islands of Northern Australia. Journal of Clinical Microbiology.","DOI":"10.1128\/JCM.00418-13"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"14240","DOI":"10.1073\/pnas.0403302101","article-title":"Genomic plasticity of the causative agent of melioidosis, Burkholderia pseudomallei","volume":"101","author":"MTG Holden","year":"2004","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"ref50","doi-asserted-by":"crossref","unstructured":"Ketterlinus R, Hsieh S-Y, Teng S-H, Lee H, Pusch W (2005) Fishing for biomarkers: analyzing mass spectrometry data with the new ClinProTools software. BioTechniques Suppl: 37\u201340.","DOI":"10.2144\/05386SU07"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1093\/jac\/dkf165","article-title":"Cloning of the class D beta-lactamase gene from Burkholderia pseudomallei and studies on its expression in ceftazidime-susceptible and -resistant strains","volume":"50","author":"P Niumsup","year":"2002","journal-title":"The Journal of antimicrobial chemotherapy"},{"key":"ref52","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1006\/mcpr.1999.0221","article-title":"PCR-RFLP analysis of the flagellin sequences for identification of Burkholderia pseudomallei and Burkholderia cepacia from clinical isolates","volume":"13","author":"S Tungpradabkul","year":"1999","journal-title":"Molecular and cellular probes"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"7008","DOI":"10.1128\/JB.185.23.7008-7014.2003","article-title":"Role of the stationary growth phase sigma factor RpoS of Burkholderia pseudomallei in response to physiological stress conditions","volume":"185","author":"B Subsin","year":"2003","journal-title":"J Bacteriol"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0099160","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,3]],"date-time":"2025-05-03T09:17:22Z","timestamp":1746263842000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0099160"}},"subtitle":[],"editor":[{"given":"Fatah","family":"Kashanchi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2014,6,10]]},"references-count":53,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2014,6,10]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0099160","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,6,10]]}}}