{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T17:40:01Z","timestamp":1748367601989},"reference-count":17,"publisher":"Public Library of Science (PLoS)","issue":"6","license":[{"start":{"date-parts":[[2014,6,17]],"date-time":"2014-06-17T00:00:00Z","timestamp":1402963200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0099351","type":"journal-article","created":{"date-parts":[[2014,6,17]],"date-time":"2014-06-17T20:19:13Z","timestamp":1403036353000},"page":"e99351","update-policy":"http:\/\/dx.doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":7,"title":["Impedimetric Detection of Mutant p53 Biomarker-Driven Metastatic Breast Cancers under Hyposmotic Pressure"],"prefix":"10.1371","volume":"9","author":[{"given":"Menglu","family":"Shi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nataly","family":"Shtraizent","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alla","family":"Polotskaia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jill","family":"Bargonetti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Matsui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2014,6,17]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"2007","DOI":"10.1093\/carcin\/bgs232","article-title":"The rebel angel: mutant p53 as the driving oncogene in breast cancer","volume":"33","author":"D Walerych","year":"2012","journal-title":"Carcinogenesis"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/j.cell.2011.12.017","article-title":"Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway","volume":"148","author":"WA Freed-Pastor","year":"2012","journal-title":"Cell"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1038\/ncb1571","article-title":"p53 gain-of-function cancer mutants induce genetic instability by inactivating ATM","volume":"9","author":"H Song","year":"2007","journal-title":"Nature cell biology"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1038\/onc.2009.376","article-title":"A common gain of function of p53 cancer mutants in inducing genetic instability","volume":"29","author":"DP Liu","year":"2010","journal-title":"Oncogene"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1038\/nrc2693","article-title":"When mutants gain new powers: news from the mutant p53 field","volume":"9","author":"R Brosh","year":"2009","journal-title":"Nat Rev Cancer"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"2212","DOI":"10.1038\/sj.onc.1210296","article-title":"Mutant p53: an oncogenic transcription factor","volume":"26","author":"S Strano","year":"2007","journal-title":"Oncogene"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"5166","DOI":"10.1073\/pnas.95.9.5166","article-title":"An oncogenic form of p53 confers a dominant, gain-of-function phenotype that disrupts spindle checkpoint control","volume":"95","author":"A Gualberto","year":"1998","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.cell.2009.01.039","article-title":"A Mutant-p53\/Smad Complex Opposes p63 to Empower TGF\u03b2-Induced Metastasis","volume":"137","author":"M Adorno","year":"2009","journal-title":"Cell"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1016\/j.cell.2004.11.006","article-title":"Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome","volume":"119","author":"GA Lang","year":"2004","journal-title":"Cell"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1016\/j.cell.2004.11.004","article-title":"Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome","volume":"119","author":"KP Olive","year":"2004","journal-title":"Cell"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"6495","DOI":"10.1021\/ac1007877","article-title":"Screening and Identification of Small Molecule Compounds Perturbing Mitosis Using Time-Dependent Cellular Response Profiles","volume":"82","author":"N Ke","year":"2010","journal-title":"Analytical Chemistry"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"10167","DOI":"10.1021\/ac9021049","article-title":"Label-Free Cancer Cell Detection with Impedimetric Transducers","volume":"81","author":"R de la Rica","year":"2009","journal-title":"Analytical Chemistry"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S0141-0229(99)00008-3","article-title":"The dielectric properties of biological cells at radiofrequencies: applications in biotechnology","volume":"25","author":"GH Markx","year":"1999","journal-title":"Enzyme and Microbial Technology"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1002\/cyto.a.20141","article-title":"Impedance spectroscopy flow cytometry: On-chip label-free cell differentiation","volume":"65A","author":"K Cheung","year":"2005","journal-title":"Cytometry Part A"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1016\/j.elecom.2006.05.028","article-title":"Polysilicon interdigitated electrodes as impedimetric sensors","volume":"8","author":"R de la Rica","year":"2006","journal-title":"Electrochemistry Communications"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1007\/s002329900195","article-title":"Rapid swelling of a CHO-K1 aspartate\/glutamate transport mutant in hypo-osmotic medium","volume":"156","author":"X Tong","year":"1997","journal-title":"J Membr Biol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"3689","DOI":"10.1529\/biophysj.104.045476","article-title":"Optical deformability as an inherent cell marker for testing malignant transformation and metastatic competence","volume":"88","author":"J Guck","year":"2005","journal-title":"Biophys J"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0099351","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,11]],"date-time":"2019-08-11T16:25:52Z","timestamp":1565540752000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0099351"}},"subtitle":[],"editor":[{"given":"Chunhong","family":"Yan","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2014,6,17]]},"references-count":17,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2014,6,17]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0099351","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,6,17]]}}}