{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T06:01:37Z","timestamp":1789538497816,"version":"build-2803163510"},"reference-count":38,"publisher":"Public Library of Science (PLoS)","issue":"6","license":[{"start":{"date-parts":[[2014,6,25]],"date-time":"2014-06-25T00:00:00Z","timestamp":1403654400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0100815","type":"journal-article","created":{"date-parts":[[2014,6,25]],"date-time":"2014-06-25T20:28:09Z","timestamp":1403728089000},"page":"e100815","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":69,"title":["Dietary Cadmium Intake and Risk of Breast, Endometrial and Ovarian Cancer in Danish Postmenopausal Women: A Prospective Cohort Study"],"prefix":"10.1371","volume":"9","author":[{"given":"Kirsten T.","family":"Eriksen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jytte","family":"Halkj\u00e6r","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mette","family":"S\u00f8rensen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaymie R.","family":"Meliker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jane A.","family":"McElroy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Tj\u00f8nneland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ole","family":"Raaschou-Nielsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2014,6,25]]},"reference":[{"key":"ref1","unstructured":"The NORDCAN project. <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www-dep.iarc.fr\/NORDCAN\/DK\/frame.asp\" xlink:type=\"simple\">http:\/\/www-dep.iarc.fr\/NORDCAN\/DK\/frame.asp<\/ext-link>. Accessed 2014 January 16."},{"key":"ref2","doi-asserted-by":"crossref","unstructured":"Schottenfeld D, Fraumeni JF Jr (2006) Cancer Epidemiology and Prevention. 3rd ed. New York, NY: Oxford University Press.","DOI":"10.1093\/acprof:oso\/9780195149616.001.0001"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"867","DOI":"10.3390\/medicina46120121","article-title":"Environmental factors and breast cancer","volume":"46","author":"L Strumylaite","year":"2010","journal-title":"Medicina (Kaunas)"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"1681","DOI":"10.1093\/jnci\/87.22.1681","article-title":"Proportion of breast cancer cases in the United States explained by well-established risk factors","volume":"87","author":"MP Madigan","year":"1995","journal-title":"J Natl Cancer Inst"},{"key":"ref5","unstructured":"IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. Lyon, France: International Agency for Research on Cancer. <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/monographs.iarc.fr\/ENG\/Classification\/index.php\" xlink:type=\"simple\">http:\/\/monographs.iarc.fr\/ENG\/Classification\/index.php<\/ext-link>. Accessed 2014 January 16."},{"key":"ref6","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.taap.2009.01.011","article-title":"Mechanisms of cadmium carcinogenesis","volume":"238","author":"P Joseph","year":"2009","journal-title":"Toxicol Appl Pharmacol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.mrfmmm.2003.07.011","article-title":"Cadmium carcinogenesis","volume":"533","author":"MP Waalkes","year":"2003","journal-title":"Mutat Res"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.mce.2006.10.013","article-title":"Cadmium induces mitogenic signaling in breast cancer cell by an ERalpha-dependent mechanism","volume":"264","author":"M Brama","year":"2007","journal-title":"Mol Cell Endocrinol"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"16896","DOI":"10.1016\/S0021-9258(19)89474-7","article-title":"Effect of cadmium on estrogen receptor levels and estrogen-induced responses in human breast cancer cells","volume":"269","author":"P Garcia-Morales","year":"1994","journal-title":"J Biol Chem"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1111\/j.1600-079X.2006.00315.x","article-title":"Melatonin inhibits both ER alpha activation and breast cancer cell proliferation induced by a metalloestrogen, cadmium","volume":"40","author":"C Martinez-Campa","year":"2006","journal-title":"J Pineal Res"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1016\/j.taap.2007.12.017","article-title":"Rapid activation of ERK1\/2 and AKT in human breast cancer cells by cadmium","volume":"228","author":"Z Liu","year":"2008","journal-title":"Toxicol Appl Pharmacol"},{"key":"ref12","first-page":"545","article-title":"Activation of estrogen receptor-alpha by the heavy metal cadmium","volume":"14","author":"A Stoica","year":"2000","journal-title":"Mol Endocrinol"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1093\/toxsci\/kfh180","article-title":"Development and characterization of a cell line that stably expresses an estrogen-responsive luciferase reporter for the detection of estrogen receptor agonist and antagonists","volume":"81","author":"VS Wilson","year":"2004","journal-title":"Toxicol Sci"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1038\/nm902","article-title":"Cadmium mimics the in vivo effects of estrogen in the uterus and mammary gland","volume":"9","author":"MD Johnson","year":"2003","journal-title":"Nat Med"},{"key":"ref15","first-page":"1","article-title":"Health effects of cadmium exposure\u2013a review of the literature and a risk estimate","volume":"24","author":"L Jarup","year":"1998","journal-title":"Scand J Work Environ Health"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.taap.2009.04.020","article-title":"Current status of cadmium as an environmental health problem","volume":"238","author":"L Jarup","year":"2009","journal-title":"Toxicol Appl Pharmacol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1002\/pros.20668","article-title":"Prostate-specific antigen levels in relation to cadmium exposure and zinc intake: results from the 2001\u20132002 National Health and Nutrition Examination Survey","volume":"68","author":"E van Wijngaarden","year":"2008","journal-title":"Prostate"},{"key":"ref18","first-page":"101","article-title":"Factors influencing the cadmium body burden in a population study","volume":"118","author":"F Sartor","year":"1992","journal-title":"IARC Sci Publ"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1158\/0008-5472.CAN-11-0735","article-title":"Dietary cadmium exposure and risk of postmenopausal breast cancer: a population-based prospective cohort study","volume":"72","author":"B Julin","year":"2012","journal-title":"Cancer Res"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1007\/s10552-012-9953-6","article-title":"Dietary cadmium and risk of invasive postmenopausal breast cancer in the VITAL cohort","volume":"23","author":"SV Adams","year":"2012","journal-title":"Cancer Causes Control"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1097\/EDE.0b013e31824d063c","article-title":"Long-term dietary cadmium intake and cancer incidence","volume":"23","author":"N Sawada","year":"2012","journal-title":"Epidemiology"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"6435","DOI":"10.1158\/0008-5472.CAN-08-0329","article-title":"Long-term dietary cadmium intake and postmenopausal endometrial cancer incidence: a population-based prospective cohort study","volume":"68","author":"A Akesson","year":"2008","journal-title":"Cancer Res"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1038\/bjc.2011.238","article-title":"Dietary cadmium exposure and risk of epithelial ovarian cancer in a prospective cohort of Swedish women","volume":"105","author":"B Julin","year":"2011","journal-title":"Br J Cancer"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1080\/14034940601047986","article-title":"Study design, exposure variables, and socioeconomic determinants of participation in Diet, Cancer and Health: a population-based prospective cohort study of 57,053 men and women in Denmark","volume":"35","author":"A Tjonneland","year":"2007","journal-title":"Scand J Public Health"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"593","DOI":"10.3109\/02841868809091756","article-title":"Danish Breast Cancer Cooperative Group (DBCG). Structure and results of the organization","volume":"27","author":"K Fischerman","year":"1988","journal-title":"Acta Oncol"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1080\/02652030110087447","article-title":"Monitoring the content and intake of trace elements from food in Denmark","volume":"19","author":"EH Larsen","year":"2002","journal-title":"Food Addit Contam"},{"key":"ref27","unstructured":"Lauritsen J (1998) Foodcalc 1.3. <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.ibt.ku.dk\/jesper\/foodcalc\/\" xlink:type=\"simple\">http:\/\/www.ibt.ku.dk\/jesper\/foodcalc\/<\/ext-link>."},{"key":"ref28","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1016\/S0895-4356(99)00102-X","article-title":"Analysis of case-cohort designs","volume":"52","author":"WE Barlow","year":"1999","journal-title":"J Clin Epidemiol"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.ijheh.2013.03.010","article-title":"Dietary cadmium intake and breast cancer risk in Japanese women: A case-control study","volume":"217","author":"H Itoh","year":"2014","journal-title":"Int J Hyg Environ Health"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"804","DOI":"10.18632\/aging.100226","article-title":"Environmental cadmium and breast cancer risk","volume":"2","author":"CM Gallagher","year":"2010","journal-title":"Aging (Albany NY)"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1093\/jnci\/djj233","article-title":"Cadmium exposure and breast cancer risk","volume":"98","author":"JA McElroy","year":"2006","journal-title":"J Natl Cancer Inst"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"1558","DOI":"10.1158\/1055-9965.1558.13.10","article-title":"Etiology of hormone receptor-defined breast cancer: a systematic review of the literature","volume":"13","author":"MD Althuis","year":"2004","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.taap.2010.02.005","article-title":"The membrane estrogen receptor GPR30 mediates cadmium-induced proliferation of breast cancer cells","volume":"245","author":"X Yu","year":"2010","journal-title":"Toxicol Appl Pharmacol"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1023\/B:BREA.0000019964.33963.09","article-title":"The effect of environment on breast cancer risk","volume":"84","author":"YM Coyle","year":"2004","journal-title":"Breast Cancer Res Treat"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1016\/0002-9378(90)90420-C","article-title":"The antiestrogenic effect of cigarette smoking in women","volume":"162","author":"JA Baron","year":"1990","journal-title":"Am J Obstet Gynecol"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1080\/009841096161258","article-title":"Induction of c-myc and c-jun proto-oncogene expression in rat L6 myoblasts by cadmium is inhibited by zinc preinduction of the metallothionein gene","volume":"48","author":"MK Abshire","year":"1996","journal-title":"J Toxicol Environ Health"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/0300-483X(92)90194-J","article-title":"Possible mechanism for zinc protection against cadmium cytotoxicity in cultured vascular endothelial cells","volume":"76","author":"T Kaji","year":"1992","journal-title":"Toxicology"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1016\/0016-5085(78)90138-5","article-title":"Increased dietary cadmium absorption in mice and human subjects with iron deficiency","volume":"74","author":"PR Flanagan","year":"1978","journal-title":"Gastroenterology"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0100815","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,14]],"date-time":"2023-07-14T15:46:08Z","timestamp":1689349568000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0100815"}},"subtitle":[],"editor":[{"given":"Chunyan","family":"He","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2014,6,25]]},"references-count":38,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2014,6,25]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0100815","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,6,25]]}}}