{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T16:38:59Z","timestamp":1791304739544,"version":"4.3.1"},"reference-count":28,"publisher":"Public Library of Science (PLoS)","issue":"10","license":[{"start":{"date-parts":[[2014,10,3]],"date-time":"2014-10-03T00:00:00Z","timestamp":1412294400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0107939","type":"journal-article","created":{"date-parts":[[2014,10,3]],"date-time":"2014-10-03T17:46:54Z","timestamp":1412358414000},"page":"e107939","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":38,"title":["Sequence and Annotation of the Apicoplast Genome of the Human Pathogen Babesia microti"],"prefix":"10.1371","volume":"9","author":[{"given":"Aprajita","family":"Garg","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Stein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ankit","family":"Dwivedi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roger","family":"Frutos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuel","family":"Cornillot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Choukri Ben","family":"Mamoun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2014,10,3]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"2397","DOI":"10.1056\/NEJMra1202018","article-title":"Human babesiosis","volume":"366","author":"E Vannier","year":"2012","journal-title":"N Engl J Med"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1016\/S0020-7519(00)00137-5","article-title":"Human babesiosis: an emerging tick-borne disease","volume":"30","author":"AM Kjemtrup","year":"2000","journal-title":"International Journal for Parasitology"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/j.idc.2008.03.010","article-title":"Human babesiosis","volume":"22","author":"E Vannier","year":"2008","journal-title":"Infectious Disease Clinics of North America"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1056\/NEJM199807163390304","article-title":"Persistent parasitemia after acute babesiosis","volume":"339","author":"PJ Krause","year":"1998","journal-title":"N Engl J Med"},{"key":"ref5","first-page":"2011","article-title":"Committee on lyme disease and other tick-borne diseases. Critical needs and gaps in understanding. Prevention, amelioration, and resolution of lyme and other tick-borne diseases. The Short-term and long-term outcomes. The National Academies Press. Washington, D","volume":"C","year":"2011"},{"key":"ref6","unstructured":"CDC (2011) Nationally Notifiable Infectious Conditions, United States 2011, Babesiosis."},{"key":"ref7","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1128\/CMR.00022-10","article-title":"Transfusion-transmitted Babesia spp: bull's-eye on Babesia microti","volume":"24","author":"DA Leiby","year":"2011","journal-title":"Clin Microbiol Rev"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1111\/j.1537-2995.2012.03612.x","article-title":"Preventing transfusion-transmitted babesiosis: preliminary experience of the first laboratory-based blood donor screening program","volume":"52","author":"C Young","year":"2012","journal-title":"Transfusion"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"509","DOI":"10.7326\/0003-4819-155-8-201110180-00362","article-title":"Transfusion-associated babesiosis in the United States: a description of cases","volume":"155","author":"BL Herwaldt","year":"2011","journal-title":"Ann Intern Med"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"1454","DOI":"10.1056\/NEJM200011163432004","article-title":"Atovaquone and azithromycin for the treatment of babesiosis","volume":"343","author":"PJ Krause","year":"2000","journal-title":"N Engl J Med"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"9102","DOI":"10.1093\/nar\/gks700","article-title":"Sequencing of the smallest Apicomplexan genome from the human pathogen Babesia microti","volume":"40","author":"E Cornillot","year":"2012","journal-title":"Nucleic Acids Res"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"e72657","DOI":"10.1371\/journal.pone.0072657","article-title":"Whole genome mapping and re-organization of the nuclear and mitochondrial genomes of Babesia microti isolates","volume":"8","author":"E Cornillot","year":"2013","journal-title":"PLoS One"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1038\/nrmicro843","article-title":"Tropical infectious diseases: metabolic maps and functions of the Plasmodium falciparum apicoplast","volume":"2","author":"SA Ralph","year":"2004","journal-title":"Nat Rev Microbiol"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.micinf.2009.12.010","article-title":"Apicoplast: keep it or leave it","volume":"12","author":"T Fleige","year":"2010","journal-title":"Microbes Infect"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1146\/annurev-micro-092412-155741","article-title":"The algal past and parasite present of the apicoplast","volume":"67","author":"GG van Dooren","year":"2013","journal-title":"Annu Rev Microbiol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1186\/1471-2164-13-622","article-title":"Novel type of linear mitochondrial genomes with dual flip-flop inversion system in apicomplexan parasites, Babesia microti and Babesia rodhaini","volume":"13","author":"K Hikosaka","year":"2012","journal-title":"BMC Genomics"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1093\/bioinformatics\/16.10.944","article-title":"Artemis: sequence visualization and annotation","volume":"16","author":"K Rutherford","year":"2000","journal-title":"Bioinformatics"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"W686","DOI":"10.1093\/nar\/gki366","article-title":"The tRNAscan-SE, snoscan and snoGPS web servers for the detection of tRNAs and snoRNAs","volume":"33","author":"P Schattner","year":"2005","journal-title":"Nucleic Acids Res"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1093\/bioinformatics\/bti054","article-title":"Circular genome visualization and exploration using CGView","volume":"21","author":"P Stothard","year":"2005","journal-title":"Bioinformatics"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"e11147","DOI":"10.1371\/journal.pone.0011147","article-title":"progressiveMauve: multiple genome alignment with gene gain, loss and rearrangement","volume":"5","author":"AE Darling","year":"2010","journal-title":"PLoS One"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"3422","DOI":"10.1093\/bioinformatics\/bti553","article-title":"ACT: the Artemis Comparison Tool","volume":"21","author":"TJ Carver","year":"2005","journal-title":"Bioinformatics"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"W465","DOI":"10.1093\/nar\/gkn180","article-title":"Phylogeny.fr: robust phylogenetic analysis for the non-specialist","volume":"36","author":"A Dereeper","year":"2008","journal-title":"Nucleic Acids Res"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"D290","DOI":"10.1093\/nar\/gkr1065","article-title":"The Pfam protein families database","volume":"40","author":"M Punta","year":"2012","journal-title":"Nucleic Acids Res"},{"key":"ref24","first-page":"166","article-title":"TMbase - A database of membrane spanning proteins segments","volume":"374","author":"K Hofmann","year":"1993","journal-title":"Biol Chem"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/0014-5793(94)80351-X","article-title":"Existence of nuclear-encoded 5S-rRNA in bovine mitochondria","volume":"338","author":"S Yoshionari","year":"1994","journal-title":"FEBS Lett"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"2375","DOI":"10.1091\/mbc.9.9.2375","article-title":"Evidence for the presence of 5S rRNA in mammalian mitochondria","volume":"9","author":"PJ Magalhaes","year":"1998","journal-title":"Mol Biol Cell"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"10949","DOI":"10.1073\/pnas.1003335107","article-title":"A common red algal origin of the apicomplexan, dinoflagellate, and heterokont plastids","volume":"107","author":"J Janouskovec","year":"2010","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"3196","DOI":"10.1128\/AAC.05488-11","article-title":"Apicoplast-targeting antibacterials inhibit the growth of Babesia parasites","volume":"56","author":"M Aboulaila","year":"2012","journal-title":"Antimicrob Agents Chemother"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0107939","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,8]],"date-time":"2020-05-08T18:48:27Z","timestamp":1588963707000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0107939"}},"subtitle":[],"editor":[{"given":"Ikuo","family":"Igarashi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2014,10,3]]},"references-count":28,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2014,10,3]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0107939","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,10,3]]}}}