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In: Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. Available: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.cochrane-handbook.org\" xlink:type=\"simple\">www.cochrane-handbook.org<\/ext-link>."},{"key":"ref14","unstructured":"Higgins JPT, Altman DG, Sterne JAC (2011) Chapter 8: assessing risk of bias in included studies. In: Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. Available: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.cochrane-handbook.org\" xlink:type=\"simple\">www.cochrane-handbook.org<\/ext-link>."},{"key":"ref15","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.2307\/2533446","article-title":"Operating characteristics of a rank correlation test for publication bias","volume":"50(4)","author":"CB Begg","year":"1994","journal-title":"Biometrics"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"1490","DOI":"10.1136\/bmj.328.7454.1490","article-title":"Grading quality of evidence and strength of recommendations","volume":"328","author":"D Atkins","year":"2004","journal-title":"BMJ"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1378\/chest.129.1.174","article-title":"Grading strength of recommendations and quality of evidence in clinical guidelines","volume":"129","author":"G Guyatt","year":"2006","journal-title":"Chest"},{"key":"ref18","first-page":"200","article-title":"The prophylactic effect of dexamethasone on postoperative nausea and vomiting in women undergoing thyroidectomy: a comparison of droperidol with saline","volume":"89","author":"JJ Wang","year":"1999","journal-title":"Anesth Analg"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"1404","DOI":"10.1097\/00000539-200012000-00019","article-title":"The use of dexamethasone for preventing postoperative nausea and vomiting in females undergoing thyroidectomy: a dose-ranging study","volume":"91","author":"JJ Wang","year":"2000","journal-title":"Anesth Analg"},{"key":"ref20","first-page":"151","article-title":"Prevention of PONV with dexamethasone in female patients undergoing desflurane anesthesia for thyroidectomy","volume":"39","author":"Y Lee","year":"2001","journal-title":"Acta Anaesthesiol Sin"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/j.otohns.2006.09.013","article-title":"Efficacy of dexamethasone for reducing postoperative nausea and vomiting and analgesic requirements after thyroidectomy","volume":"136","author":"Y Fujii","year":"2007","journal-title":"Otolaryngol Head Neck Surg"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1097\/SLA.0b013e31818c709a","article-title":"Randomized controlled trial on single dose steroid before thyroidectomy for benign disease to improve postoperative nausea, pain, and vocal function","volume":"248","author":"M Worni","year":"2008","journal-title":"Ann Surg"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1002\/hed.21543","article-title":"Dexamethasone prophylaxis before thyroidectomy to reduce postoperative nausea, pain, and vocal dysfunction: a randomized clinical controlled trial","volume":"33","author":"F Feroci","year":"2011","journal-title":"Head Neck 2011"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1111\/j.1399-6576.2012.02654.x","article-title":"Dexamethasone does not reduce pain or analgesic consumption after thyroid surgery; 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