{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T13:52:05Z","timestamp":1776865925335,"version":"3.51.2"},"reference-count":33,"publisher":"Public Library of Science (PLoS)","issue":"10","license":[{"start":{"date-parts":[[2014,10,28]],"date-time":"2014-10-28T00:00:00Z","timestamp":1414454400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0111073","type":"journal-article","created":{"date-parts":[[2014,10,28]],"date-time":"2014-10-28T18:02:18Z","timestamp":1414519338000},"page":"e111073","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":8,"title":["Diabetes, Prediabetes and the Survival of Nasopharyngeal Carcinoma: A Study of 5,860 Patients"],"prefix":"10.1371","volume":"9","author":[{"given":"Pu-Yun","family":"OuYang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhen","family":"Su","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie","family":"Tang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao-Wen","family":"Lan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan-Ping","family":"Mao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wuguo","family":"Deng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fang-Yun","family":"Xie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2014,10,28]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1674","DOI":"10.2337\/dc10-0666","article-title":"Diabetes and cancer: a consensus report","volume":"33","author":"E Giovannucci","year":"2010","journal-title":"Diabetes Care"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1080\/01635581.2012.676141","article-title":"Diabetes mellitus and cancer risk in a network of case-control studies","volume":"64","author":"C Bosetti","year":"2012","journal-title":"Nutr Cancer"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1002\/ijc.25362","article-title":"Risk of cancer in a large cohort of U.S. veterans with diabetes","volume":"128","author":"EA Atchison","year":"2011","journal-title":"Int J Cancer"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1038\/bjc.2012.566","article-title":"Fasting blood glucose is a novel prognostic indicator for extranodal natural killer\/T-cell lymphoma, nasal type","volume":"108","author":"Q Cai","year":"2013","journal-title":"Br J Cancer"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/j.lungcan.2011.10.019","article-title":"Fasting blood glucose level and prognosis in non-small cell lung cancer (NSCLC) patients","volume":"76","author":"J Luo","year":"2012","journal-title":"Lung Cancer"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1245\/s10434-009-0789-6","article-title":"Preoperative diabetes mellitus and long-term survival after resection of pancreatic adenocarcinoma","volume":"17","author":"CK Chu","year":"2010","journal-title":"Ann Surg Oncol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1200\/JCO.2010.29.3183","article-title":"Clinically defined type 2 diabetes mellitus and prognosis in early-stage breast cancer","volume":"29","author":"K Erickson","year":"2011","journal-title":"J Clin Oncol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"3011","DOI":"10.1093\/annonc\/mdt367","article-title":"Diabetes in relation to breast cancer relapse and all-cause mortality in elderly breast cancer patients: a FOCUS study analysis","volume":"24","author":"M Kiderlen","year":"2013","journal-title":"Ann Oncol"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"3881","DOI":"10.1016\/j.ejca.2013.08.004","article-title":"High fasting blood glucose and obesity significantly and independently increase risk of breast cancer death in hormone receptor-positive disease","volume":"49","author":"P Minicozzi","year":"2013","journal-title":"Eur J Cancer"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.jpeds.2009.01.072","article-title":"Hyperglycemia during induction therapy is associated with poorer survival in children with acute lymphocytic leukemia","volume":"155","author":"RY Sonabend","year":"2009","journal-title":"J Pediatr"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"1847","DOI":"10.1038\/bjc.2014.68","article-title":"Diabetes and prognosis in older persons with colorectal cancer","volume":"110","author":"J Luo","year":"2014","journal-title":"Br J Cancer"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1200\/JCO.2003.07.125","article-title":"Impact of diabetes mellitus on outcomes in patients with colon cancer","volume":"21","author":"JA Meyerhardt","year":"2003","journal-title":"J Clin Oncol"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1158\/1055-9965.EPI-11-0590","article-title":"History of diabetes and risk of head and neck cancer: a pooled analysis from the international head and neck cancer epidemiology consortium","volume":"21","author":"M Stott-Miller","year":"2012","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1007\/s10654-013-9865-0","article-title":"Physical activity, diabetes, and risk of thyroid cancer: a systematic review and meta-analysis","volume":"28","author":"D Schmid","year":"2013","journal-title":"Eur J Epidemiol"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"1765","DOI":"10.1158\/1055-9965.EPI-06-0353","article-title":"The enigmatic epidemiology of nasopharyngeal carcinoma","volume":"15","author":"ET Chang","year":"2006","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"2041","DOI":"10.1016\/S0140-6736(05)66698-6","article-title":"Nasopharyngeal carcinoma","volume":"365","author":"WI Wei","year":"2005","journal-title":"Lancet"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1385\/MO:23:3:341","article-title":"Impact of diabetes mellitus on treatment outcomes in patients with nasopharyngeal cancer","volume":"23","author":"H Liu","year":"2006","journal-title":"Med Oncol"},{"key":"ref18","unstructured":"Edge SB, Byrd DR, Compton CC, Fritz AG, Greene FL, <etal>et al<\/etal>.. (2010) AJCC cancer staging handbook from the AJCC cancer staging manual; Edge SB, Byrd DR, Compton CC, Fritz AG, Greene FL et al., editors. New York: Springer."},{"key":"ref19","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/j.ijrobp.2010.03.024","article-title":"How does intensity-modulated radiotherapy versus conventional two-dimensional radiotherapy influence the treatment results in nasopharyngeal carcinoma patients?","volume":"80","author":"SZ Lai","year":"2011","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"S81","DOI":"10.2337\/dc14-S081","article-title":"American Diabetes Association. Diagnosis and classification of diabetes mellitus","volume":"37","journal-title":"Diabetes Care"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/j.radonc.2013.10.020","article-title":"Long-term outcomes of intensity-modulated radiotherapy for 868 patients with nasopharyngeal carcinoma: An analysis of survival and treatment toxicities","volume":"110","author":"X Sun","year":"2014","journal-title":"Radiother Oncol"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1016\/S1470-2045(12)70102-X","article-title":"Prognostic value of a microRNA signature in nasopharyngeal carcinoma: a microRNA expression analysis","volume":"13","author":"N Liu","year":"2012","journal-title":"Lancet Oncol"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1038\/bjc.2013.343","article-title":"Prognostic impact of family history in southern Chinese patients with undifferentiated nasopharyngeal carcinoma","volume":"109","author":"PY Ouyang","year":"2013","journal-title":"Br J Cancer"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1080\/01621459.1958.10501452","article-title":"Nonparametric estimation from incomplete observation","volume":"53","author":"EL Kaplan","year":"1958","journal-title":"J Am Stat Assoc"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1111\/j.2517-6161.1972.tb00899.x","article-title":"Regression models and life tables","volume":"34","author":"DR Cox","year":"1972","journal-title":"J R Stat Soc B"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"1867","DOI":"10.1007\/s00125-010-1796-7","article-title":"Diabetes, prediabetes and cancer mortality","volume":"53","author":"XH Zhou","year":"2010","journal-title":"Diabetologia"},{"key":"ref27","doi-asserted-by":"crossref","unstructured":"Hofner T, Zeier M, Hatiboglu G, Eisen C, Schonberg G, <etal>et al<\/etal>.. (2013) The impact of type 2 diabetes on the outcome of localized renal cell carcinoma. World J Urol.","DOI":"10.1007\/s00345-013-1231-z"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1056\/NEJMoa1203858","article-title":"Basal insulin and cardiovascular and other outcomes in dysglycemia","volume":"367","author":"HC Gerstein","year":"2012","journal-title":"N Engl J Med"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1038\/ncponc0062","article-title":"Therapy insight: Influence of type 2 diabetes on the development, treatment and outcomes of cancer","volume":"2","author":"LC Richardson","year":"2005","journal-title":"Nat Clin Pract Oncol"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"e93132","DOI":"10.1371\/journal.pone.0093132","article-title":"Cancer specific mortality in insulin-treated type 2 diabetes patients","volume":"9","author":"S Ioacara","year":"2014","journal-title":"PLoS One"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"3069","DOI":"10.1200\/JCO.2012.46.7043","article-title":"Metformin use and all-cause and prostate cancer-specific mortality among men with diabetes","volume":"31","author":"D Margel","year":"2013","journal-title":"J Clin Oncol"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"2285","DOI":"10.1158\/1055-9965.EPI-13-0546","article-title":"Prognostic impact of cigarette smoking on the survival of patients with established nasopharyngeal carcinoma","volume":"22","author":"PY Ouyang","year":"2013","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"1923","DOI":"10.1016\/j.ejca.2013.01.027","article-title":"Pretreatment body mass index as an independent prognostic factor in patients with locoregionally advanced nasopharyngeal carcinoma treated with chemoradiotherapy: findings from a randomised trial","volume":"49","author":"PY Huang","year":"2013","journal-title":"Eur J Cancer"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0111073","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,4]],"date-time":"2024-06-04T12:56:17Z","timestamp":1717505777000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0111073"}},"subtitle":[],"editor":[{"given":"Chang-Qing","family":"Gao","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2014,10,28]]},"references-count":33,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2014,10,28]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0111073","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,10,28]]}}}