{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T11:44:36Z","timestamp":1789127076645,"version":"build-2803163510"},"reference-count":35,"publisher":"Public Library of Science (PLoS)","issue":"11","license":[{"start":{"date-parts":[[2014,11,6]],"date-time":"2014-11-06T00:00:00Z","timestamp":1415232000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0112034","type":"journal-article","created":{"date-parts":[[2014,11,6]],"date-time":"2014-11-06T14:29:22Z","timestamp":1415284162000},"page":"e112034","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":85,"title":["Prediction of Interactions between Viral and Host Proteins Using Supervised Machine Learning Methods"],"prefix":"10.1371","volume":"9","author":[{"given":"Ranjan Kumar","family":"Barman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sudipto","family":"Saha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santasabuj","family":"Das","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2014,11,6]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1016\/j.ymeth.2012.06.011","article-title":"Computational analysis of interactomes: Current and future perspectives for bioinformatics approaches to model the host\u2013pathogen interaction space","volume":"57","author":"R Arnold","year":"2012","journal-title":"Methods"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1230001","DOI":"10.1142\/S0219720012300018","article-title":"Progress in computational studies of host-pathogen interactions","volume":"11(2)","author":"H Zhou","year":"2013","journal-title":"Journal of Bioinformatics and Computational Biology"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"S5","DOI":"10.1186\/1471-2105-13-S7-S5","article-title":"Prediction of protein-protein interactions between viruses and human by an SVM model","volume":"13","author":"G Cui","year":"2012","journal-title":"BMC Bioinformatics"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1126\/science.1087361","article-title":"A Bayesian networks approach for predicting protein-protein interactions from genomic data","volume":"302(5644)","author":"R Jansen","year":"2003","journal-title":"Science"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1186\/1471-2105-5-154","article-title":"Information assessment on predicting protein-protein interactions","volume":"5","author":"N Lin","year":"2004","journal-title":"BMC Bioinformatics"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"4337","DOI":"10.1073\/pnas.0607879104","article-title":"Predicting protein-protein interactions based only on sequences information","volume":"104(11)","author":"J Shen","year":"2007","journal-title":"Proc Natl Acad Sci"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"3025","DOI":"10.1093\/nar\/gkn159","article-title":"Using support vector machine combined with auto covariance to predict protein-protein interactions from protein sequences","volume":"36(9)","author":"Y Guo","year":"2008","journal-title":"Nucleic Acids Res"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"2137","DOI":"10.1093\/nar\/gkl219","article-title":"Prediction of yeast protein-protein interaction network: insights from the Gene Ontology and annotations","volume":"34(7)","author":"X Wu","year":"2006","journal-title":"Nucleic Acids Res"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.jtbi.2013.02.016","article-title":"A matrix based algorithm for Protein-Protein Interaction prediction using Domain-Domain Associations","volume":"326","author":"S Binny Priya","year":"2013","journal-title":"Journal of Theoretical Biology"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"S8","DOI":"10.1186\/1752-0509-5-S1-S8","article-title":"Conditional random field approach to prediction of protein\u2013protein interactions using domain information","volume":"5","author":"M Hayashida","year":"2011","journal-title":"BMC Systems Biology"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1186\/1471-2105-14-154","article-title":"Reconstituting protein interaction networks using parameter-dependent domain-domain interactions","volume":"14","author":"V Memi\u0161evic","year":"2013","journal-title":"BMC Bioinformatics"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1016\/j.meegid.2011.02.022","article-title":"Supervised learning and prediction of physical interactions between human and HIV proteins","volume":"11(5)","author":"MD Dyer","year":"2011","journal-title":"Infect Genet Evol"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"2585","DOI":"10.1110\/ps.073228407","article-title":"Host pathogen protein interactions predicted by comparative modeling","volume":"16(12)","author":"FP Davis","year":"2007","journal-title":"Protein Sci"},{"key":"ref14","unstructured":"Tastan O, Qi Y, Carbonell JG, Klein-Seetharaman J (2009) Prediction of interactions between HIV-1 and human proteins by information integration. Pac Symp Biocomput, 516\u201327."},{"key":"ref15","doi-asserted-by":"crossref","first-page":"i645","DOI":"10.1093\/bioinformatics\/btq394","article-title":"Semi-supervised multi-task learning for predicting interactions between HIV-1 and human proteins","volume":"26(18)","author":"Y Qi","year":"2010","journal-title":"Bioinformatics"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"e954","DOI":"10.1371\/journal.pntd.0000954","article-title":"Mapping protein interactions between Dengue virus and its human and insect hosts","volume":"5(2)","author":"JM Doolittle","year":"2011","journal-title":"PLoS Negl Trop Dis"},{"key":"ref17","doi-asserted-by":"crossref","unstructured":"Chatr-aryamontri A, Ceol A, Peluso D, Nardozza A, Panni S, et al. (2009) VirusMINT: a viral protein interaction database. Nucleic Acids Res 37 (Database issue): D669\u201373.","DOI":"10.1093\/nar\/gkn739"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"1658","DOI":"10.1093\/bioinformatics\/btl158","article-title":"Cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences","volume":"22(13)","author":"W Li","year":"2006","journal-title":"Bioinformatics"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"S2","DOI":"10.1186\/1471-2105-7-S1-S2","article-title":"Choosing negative examples for the prediction of protein-protein interactions","volume":"7","author":"A Ben-Hur","year":"2006","journal-title":"BMC Bioinformatics"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1186\/1743-422X-5-156","article-title":"An overview of molecular epidemiology of hepatitis B virus (HBV) in India","volume":"5","author":"S Datta","year":"2008","journal-title":"Virology Journal"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"D43","DOI":"10.1093\/nar\/gks1068","article-title":"Update on activities at the universal protein resource (UniProt) in 2013","volume":"41","author":"Consortium UniProt","year":"2013","journal-title":"Nucleic Acids Res"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"504","DOI":"10.4103\/IJMR.2010_132_05_504","article-title":"Molecular analysis of swine hepatitis E virus from north India","volume":"132","author":"N Begum","year":"2010","journal-title":"Indian J Med Res"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"3440","DOI":"10.1128\/JCM.00939-06","article-title":"Identification of genotype 1 hepatitis E virus in samples from swine in Cambodia","volume":"44(9)","author":"M Caron","year":"2006","journal-title":"Journal of Clinical Microbiology"},{"key":"ref24","doi-asserted-by":"crossref","unstructured":"Joachims T (2002) Learning to Classify Text Using Support Vector Machines. Dissertation, Kluwer.","DOI":"10.1007\/978-1-4615-0907-3"},{"key":"ref25","doi-asserted-by":"crossref","unstructured":"Hall M, Frank E, Holmes G, Pfahringer B, Reutemann P, et al. (2009) The WEKA Data Mining Software: An Update. SIGKDD Explorations 11: Issue 1.","DOI":"10.1145\/1656274.1656278"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"2495","DOI":"10.1093\/bioinformatics\/btm373","article-title":"APID2NET: unified interactome graphic analyser","volume":"23(18)","author":"J Hernandez-Toro","year":"2007","journal-title":"Bioinformatics"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1093\/bioinformatics\/btr682","article-title":"ESpritz: accurate and fast prediction of protein disorder","volume":"28(4)","author":"I Walsh","year":"2012","journal-title":"Bioinformatics"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"e7813","DOI":"10.1371\/journal.pone.0007813","article-title":"Exploiting Amino Acid Composition for Predicting Protein-Protein Interactions","volume":"4(11)","author":"S Roy","year":"2009","journal-title":"PLoS One"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1006\/jmbi.2001.4920","article-title":"Correlated sequence-signatures as markers of protein-protein interaction","volume":"311","author":"E Sprinzak","year":"2001","journal-title":"J Mol Biol"},{"key":"ref30","unstructured":"TIBCO Spotfire 5.5, Available: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/spotfire.tibco.com\/\" xlink:type=\"simple\">http:\/\/spotfire.tibco.com\/<\/ext-link>. Accessed 2014."},{"key":"ref31","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1038\/nprot.2008.211","article-title":"Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources","volume":"4(1)","author":"W Huang da","year":"2009","journal-title":"Nature Protocols"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"34979","DOI":"10.1074\/jbc.M112.374504","article-title":"The Methionine-aromatic Motif Plays a Unique Role in Stabilizing Protein Structure","volume":"287","author":"CC Valley","year":"2012","journal-title":"Journal of Biological Chemistry"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/0065-2571(94)90017-5","article-title":"Serine\/threonine protein phosphatases in the control of cell function","volume":"34","author":"AA Depaoli-Roach","year":"1994","journal-title":"Advances in Enzyme Regulation"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"6985","DOI":"10.1128\/JVI.68.11.6985-6993.1994","article-title":"Mutations in the cytoplasmic tail of herpes simplex virus glycoprotein H suppress cell fusion by a syncytial strain","volume":"68(11)","author":"DW Wilson","year":"1994","journal-title":"Journal of Virology"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1093\/bioinformatics\/btq675","article-title":"Cytoscape 2.8: new features for data integration and network visualization","volume":"27(3)","author":"ME Smoot","year":"2011","journal-title":"Bioinformatics"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0112034","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T11:42:34Z","timestamp":1747136554000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0112034"}},"subtitle":[],"editor":[{"given":"Dinesh","family":"Gupta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2014,11,6]]},"references-count":35,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2014,11,6]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0112034","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,11,6]]}}}