{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T12:26:21Z","timestamp":1777465581611,"version":"3.51.4"},"reference-count":83,"publisher":"Public Library of Science (PLoS)","issue":"11","license":[{"start":{"date-parts":[[2014,11,20]],"date-time":"2014-11-20T00:00:00Z","timestamp":1416441600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0113521","type":"journal-article","created":{"date-parts":[[2014,11,20]],"date-time":"2014-11-20T19:20:40Z","timestamp":1416511240000},"page":"e113521","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":12,"title":["The Psychosis Recent Onset GRoningen Survey (PROGR-S): Defining Dimensions and Improving Outcomes in Early Psychosis"],"prefix":"10.1371","volume":"9","author":[{"given":"Edith J.","family":"Liemburg","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stynke","family":"Castelein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank","family":"van Es","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne Neeltje","family":"Scholte-Stalenhoef","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerard","family":"van de Willige","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henderikus","family":"Smid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ellen","family":"Visser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henderikus","family":"Knegtering","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Bruggeman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2014,11,20]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1001\/archpsyc.64.1.19","article-title":"Lifetime prevalence of psychotic and bipolar I disorders in a general population","volume":"64","author":"J Perala","year":"2007","journal-title":"Arch Gen Psychiatry"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1017\/S0033291706007951","article-title":"A systematic review of longitudinal outcome studies of first-episode psychosis","volume":"36","author":"NM Menezes","year":"2006","journal-title":"Psychol Med"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.schres.2010.10.026","article-title":"Trajectories of the course of schizophrenia: From progressive deterioration to amelioration over three decades","volume":"126","author":"SZ Levine","year":"2011","journal-title":"Schizophr Res"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/S0140-6736(09)60995-8","article-title":"Schizophrenia","volume":"374","author":"J van Os","year":"2009","journal-title":"Lancet"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1177\/070674371005500803","article-title":"Clinical staging: A heuristic and practical strategy for new research and better health and social outcomes for psychotic and related mood disorders","volume":"55","author":"PD McGorry","year":"2010","journal-title":"Can J Psychiatry"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1111\/acps.12000","article-title":"Clinical and sociodemographic comparison of people at high-risk for psychosis and with first-episode psychosis","volume":"127","author":"J Zimbron","year":"2012","journal-title":"Acta Psychiatr Scand"},{"key":"ref7","first-page":"CD004718","article-title":"Early intervention for psychosis","volume":"15","author":"M Marshall","year":"2011","journal-title":"Cochrane Database Syst Rev"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1002\/bsl.2037","article-title":"Relative contributions of gender and traumatic life experience to the prediction of mental disorders in a sample of incarcerated offenders","volume":"30","author":"TD Gunter","year":"2012","journal-title":"Behav Sci Law"},{"key":"ref9","first-page":"1","article-title":"Temporal association of stress sensitivity and symptoms in individuals at clinical high risk for psychosis","volume":"43","author":"JE Devylder","year":"2012","journal-title":"Psychol Med"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1146\/annurev.psych.093008.100352","article-title":"Personality and coping","volume":"61","author":"CS Carver","year":"2010","journal-title":"Annu Rev Psychol"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1159\/000105532","article-title":"Personality dimensions in schizophrenia: Associations with symptoms and coping concurrently and 12 months later","volume":"40","author":"PH Lysaker","year":"2007","journal-title":"Psychopathology"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1093\/schbul\/sbs105","article-title":"Cognitive behavioral therapy for subjects at ultrahigh risk for developing psychosis: A randomized controlled clinical trial","volume":"38","author":"M van der Gaag","year":"2012","journal-title":"Schizophr Bull"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.psychres.2007.11.004","article-title":"Premorbid adjustment in schizophrenia and schizoaffective disorder","volume":"165","author":"R Saracco-Alvarez","year":"2009","journal-title":"Psychiatry Res"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"S33","DOI":"10.1093\/schbul\/sbr084","article-title":"Neurocognitive predictors of work outcome in recent-onset schizophrenia","volume":"37","author":"KH Nuechterlein","year":"2011","journal-title":"Schizophr Bull"},{"key":"ref15","first-page":"39","article-title":"Correlation of cognitive functions with some aspects of illness, treatment and social functioning in recurrently hospitalized schizophrenic patients","volume":"35","author":"M Bajs","year":"2011","journal-title":"Coll Antropol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1037\/0894-4105.12.3.426","article-title":"Neurocognitive deficit in schizophrenia: A quantitative review of the evidence","volume":"12","author":"RW Heinrichs","year":"1998","journal-title":"Neuropsychology"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1007\/7854_2010_42","article-title":"Neurocognition in schizophrenia","volume":"4","author":"S Kalkstein","year":"2010","journal-title":"Curr Top Behav Neurosci"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1007\/s11065-009-9098-x","article-title":"Turning it upside down: Areas of preserved cognitive function in schizophrenia","volume":"19","author":"JM Gold","year":"2009","journal-title":"Neuropsychol Rev"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1162\/0898929053467578","article-title":"Neural correlates of memory for items and for associations: An event-related functional magnetic resonance imaging study","volume":"17","author":"AM Achim","year":"2005","journal-title":"J Cogn Neurosci"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1007\/s11065-009-9109-y","article-title":"What do we know about neuropsychological aspects of schizophrenia?","volume":"19","author":"BW Palmer","year":"2009","journal-title":"Neuropsychol Rev"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1093\/schbul\/sbn044","article-title":"Neuropsychological function and dysfunction in schizophrenia and psychotic affective disorders","volume":"35","author":"A Reichenberg","year":"2009","journal-title":"Schizophr Bull"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1111\/j.1600-0447.2005.00626.x","article-title":"Neuropsychological test profiles in schizophrenia and non-psychotic depression","volume":"113","author":"BR Rund","year":"2006","journal-title":"Acta Psychiatr Scand"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/j.psc.2005.05.004","article-title":"Cognition in schizophrenia: Impairments, determinants, and functional importance","volume":"28","author":"CR Bowie","year":"2005","journal-title":"Psychiatr Clin North Am"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.schres.2012.08.013","article-title":"Prospective relationship of duration of untreated psychosis to psychopathology and functional outcome over 12years","volume":"141","author":"M Hill","year":"2012","journal-title":"Schizophr Res"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0140-6736(08)61764-X","article-title":"Second-generation versus first-generation antipsychotic drugs for schizophrenia: A meta-analysis","volume":"373","author":"S Leucht","year":"2009","journal-title":"Lancet"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1038\/sj.mp.4002136","article-title":"How effective are second-generation antipsychotic drugs? A meta-analysis of placebo-controlled trials","volume":"14","author":"S Leucht","year":"2009","journal-title":"Mol Psychiatry"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"2063","DOI":"10.1016\/S0140-6736(12)60239-6","article-title":"Antipsychotic drugs versus placebo for relapse prevention in schizophrenia: A systematic review and meta-analysis","volume":"379","author":"S Leucht","year":"2012","journal-title":"Lancet"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.schres.2005.02.010","article-title":"A meta-analysis of worldwide studies demonstrates an association between schizophrenia and tobacco smoking behaviors","volume":"76","author":"J de Leon","year":"2005","journal-title":"Schizophr Res"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.psychres.2010.03.011","article-title":"Considering a frame of reference for physical activity research related to the cardiometabolic risk profile in schizophrenia","volume":"177","author":"D Vancampfort","year":"2010","journal-title":"Psychiatry Res"},{"key":"ref30","unstructured":"Schorr SG. (2010) Drug safety in patients with psychotic disorders. Groningen: University of Groningen. pp 30\u201340."},{"key":"ref31","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1177\/0004867412450471","article-title":"Medication for psychosis\u2013consumption and consequences: The second australian national survey of psychosis","volume":"46","author":"A Waterreus","year":"2012","journal-title":"Aust N Z J Psychiatry"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1016\/0006-3223(94)00365-A","article-title":"Clozapine decreases smoking in patients with chronic schizophrenia","volume":"37","author":"J Mcevoy","year":"1995","journal-title":"Biol Psychiatry"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1111\/j.1464-5491.2007.02092.x","article-title":"Impaired glucose tolerance in first-episode drug-naive patients with schizophrenia","volume":"24","author":"LM Spelman","year":"2007","journal-title":"Diabet Med"},{"key":"ref34","unstructured":"American Psychiatric Association (2000) Diagnostic and statistical manual of mental disorders. Washington, DC."},{"key":"ref35","doi-asserted-by":"crossref","first-page":"S41","DOI":"10.1016\/S0924-9338(10)71706-5","article-title":"Management of physical health in patients with schizophrenia: Practical recommendations","volume":"25","author":"A Heald","year":"2010","journal-title":"Eur Psychiatry"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1016\/S0924-9338(10)71699-0","article-title":"The need for routine physical health care in schizophrenia","volume":"25","author":"AL Montejo","year":"2010","journal-title":"Eur Psychiatry"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.schres.2010.07.012","article-title":"Head-to-head comparisons of metabolic side effects of second generation antipsychotics in the treatment of schizophrenia: A systematic review and meta-analysis","volume":"123","author":"C Rummel-Kluge","year":"2010","journal-title":"Schizophr Res"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1017\/S2045796012000315","article-title":"Psychosis incident cohort outcome study (PICOS). A multisite study of clinical, social and biological characteristics, patterns of care and predictors of outcome in first-episode psychosis. background, methodology and overview of the patient sample","volume":"21","author":"A Lasalvia","year":"2012","journal-title":"Epidemiol Psychiatr Sci"},{"key":"ref39","first-page":"231","article-title":"The positive and negative syndrome scale (PANSS) for schizophrenia","volume":"13","author":"S Kay","year":"1987","journal-title":"Schizophr Bull"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1192\/bjp.134.4.382","article-title":"A new depression scale designed to be sensitive to change","volume":"134","author":"SA Montgomery","year":"1979","journal-title":"Br J Psychiatry"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1192\/bjp.bp.106.032532","article-title":"Development and reliability of a structured interview guide for the montgomery asberg depression rating scale (SIGMA)","volume":"192","author":"JB Williams","year":"2008","journal-title":"Br J Psychiatry"},{"key":"ref42","unstructured":"Giel R, Nienhuis F (1996) Scan 2.1: Schedules for clinical assessment in neuropsychiatry (In Dutch). Geneve\/Groningen: WHO."},{"key":"ref43","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/S0033-3182(95)71666-8","article-title":"Global assessment of functioning. A modified scale","volume":"36","author":"RC Hall","year":"1995","journal-title":"Psychosomatics"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1192\/bjp.167.5.589","article-title":"The camberwell assessment of need: The validity and reliability of an instrument to assess the needs of people with severe mental illness","volume":"167","author":"M Phelan","year":"1995","journal-title":"Br J Psychiatry"},{"key":"ref45","unstructured":"Wiersma D (1990) GSDS-II: Groningen social disabilities schedule (In Dutch: GSB-II : De Groningse sociale beperkingen schaal). Groningen: University of Groningen, Department of Social Psychiatry. 143 p."},{"key":"ref46","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1176\/appi.ajp.2007.07010042","article-title":"The MATRICS consensus cognitive battery, part 1: Test selection, reliability, and validity","volume":"165","author":"KH Nuechterlein","year":"2008","journal-title":"Am J Psychiatry"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1037\/h0054651","article-title":"Studies of interference in serial verbal reactions","volume":"18","author":"JR Stroop","year":"1935","journal-title":"Journal of Experimental Psychology"},{"key":"ref48","unstructured":"Golden CJ (1978) Stroop color and word test: A manual for clinical and experimental uses. Chicago, Illinois: Skoelting. 32 p."},{"key":"ref49","unstructured":"Spreen O, Strauss E (1998) A compendium of neuropsychological tests: Administration, norms and commentary. New York: Oxford University Press."},{"key":"ref50","unstructured":"Delis D, Kramer JK, Kaplan E, Ober BA (2000) CVLT-II. California verbal learning test. adult version. second edition. the psychological corporation. San Antonio, Texas: Harcourt Assessment Company."},{"key":"ref51","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1080\/13803390591001025","article-title":"Sustained and transient attention in the continuous performance task","volume":"28","author":"HG Smid","year":"2006","journal-title":"J Clin Exp Neuropsychol"},{"key":"ref52","unstructured":"Lezak M (1995) Neuropsychological assessment. New York: Oxford University Press."},{"key":"ref53","unstructured":"Wechsler D (1997) WAIS-III: Wechsler adult intelligence scale, administration and scoring manual. San Antonio, Texas: Psychological Corporation\/Harcourt Brace."},{"key":"ref54","unstructured":"Costa PT Jr, McCrae RR (1990) Revised NEO personality inventory (NEO-PI-R) and the five factor inventory (NEO-FFI): Professional manual. Odessa, Florida: Psychological Assessment Resources Inc."},{"key":"ref55","unstructured":"Hoekstra HA, Ormel H, De Fruyt F (1996) NEO persoonlijkheidsvragenlijsten: NEO PI-R &amp; NEO-FFI. [NEO personality inventories: NEO PI-R &amp; NEO-FFI]. Lisse, Netherlands: Swets &amp; Zeitlinger."},{"key":"ref56","unstructured":"Schreurs PJG, Van de Willige G (1988) Coping with problems and events: The Utrecht coping list UCL (In Dutch: Omgaan met problemen en gebeurtenissen: De Utrechtse copinglijst (UCL)). Lisse: Swets &amp; Zeitlinger."},{"key":"ref57","unstructured":"Verhage F (1984) Intelligentie en leeftijd: Onderzoek bij Nederlanders van twaalf tot zevenenzeventig jaar. Assen: Van Gorcum."},{"key":"ref58","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1176\/appi.ajp.2011.11010048","article-title":"Diagnostic shifts during the decade following first admission for psychosis","volume":"168","author":"EJ Bromet","year":"2011","journal-title":"Am J Psychiatry"},{"key":"ref59","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1016\/j.biopsych.2006.08.027","article-title":"Dorsolateral prefrontal cortex N-acetylaspartate\/total creatine (NAA\/tCr) loss in male recreational cannabis users","volume":"61","author":"D Hermann","year":"2007","journal-title":"Biol Psychiatry"},{"key":"ref60","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.biopsych.2009.08.040","article-title":"Antipsychotic dose equivalents and dose-years: A standardized method for comparing exposure to different drugs","volume":"67","author":"NC Andreasen","year":"2010","journal-title":"Biol Psychiatry"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.schres.2012.05.007","article-title":"Risk factors for relapse following treatment for first episode psychosis: A systematic review and meta-analysis of longitudinal studies","volume":"139","author":"M Alvarez-Jimenez","year":"2012","journal-title":"Schizophr Res"},{"key":"ref62","unstructured":"Wiersma D, De Jong A (1999) Schizophrenia and related disorders (in dutch: Schizofrenie en aanverwante stoornissen). In: De Jong A, Van den Brink W, Ormel J, Wiersma D, editors. Handboek psychiatrische epidemiologie. Maarssen: Elsevier\/De Tijdstroom."},{"key":"ref63","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.schres.2013.02.036","article-title":"Differences between first episode schizophrenia and schizoaffective disorder","volume":"147","author":"SM Cotton","year":"2013","journal-title":"Schizophr Res"},{"key":"ref64","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1111\/bdi.12057","article-title":"Characteristics of patients diagnosed with schizoaffective disorder compared with schizophrenia and bipolar disorder","volume":"15","author":"T Pagel","year":"2013","journal-title":"Bipolar Disord"},{"key":"ref65","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1111\/eip.12028","article-title":"Initial predictors of outcome in an early intervention in psychosis service","volume":"7","author":"E Harrington","year":"2013","journal-title":"Early Interv Psychiatry"},{"key":"ref66","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1001\/archpsyc.60.6.565","article-title":"Sex differences in the risk of schizophrenia: Evidence from meta-analysis","volume":"60","author":"A Aleman","year":"2003","journal-title":"Arch Gen Psychiatry"},{"key":"ref67","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.schres.2012.12.013","article-title":"Theory of mind impairments in first-episode psychosis, individuals at ultra-high risk for psychosis and in first-degree relatives of schizophrenia: Systematic review and meta-analysis","volume":"144","author":"E Bora","year":"2013","journal-title":"Schizophr Res"},{"key":"ref68","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1111\/acps.12172","article-title":"A systematic review of attachment and psychosis: Measurement, construct validity and outcomes","volume":"129","author":"AI Gumley","year":"2014","journal-title":"Acta Psychiatr Scand"},{"key":"ref69","doi-asserted-by":"crossref","first-page":"916198","DOI":"10.1155\/2012\/916198","article-title":"Gender differences in schizophrenia and first-episode psychosis: A comprehensive literature review","volume":"2012","author":"S Ochoa","year":"2012","journal-title":"Schizophr Res Treatment"},{"key":"ref70","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1007\/978-3-642-25758-2_2","article-title":"Cognitive impairment in schizophrenia","volume":"(213)","author":"RS Keefe","year":"2012","journal-title":"Handb Exp Pharmacol"},{"key":"ref71","doi-asserted-by":"crossref","first-page":"819587","DOI":"10.1155\/2013\/819587","article-title":"Neurocognitive functioning in schizophrenia and during the early phases of psychosis: Targeting cognitive remediation interventions","volume":"2013","author":"Y Zaytseva","year":"2013","journal-title":"Biomed Res Int"},{"key":"ref72","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1159\/000338608","article-title":"Can long-term outcomes be improved by shortening the duration of untreated illness in psychiatric disorders? A conceptual framework","volume":"46","author":"B Dell'Osso","year":"2013","journal-title":"Psychopathology"},{"key":"ref73","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.schres.2012.08.017","article-title":"Duration of untreated psychosis and negative symptoms\u2013a systematic review and meta-analysis of individual patient data","volume":"142","author":"N Boonstra","year":"2012","journal-title":"Schizophr Res"},{"key":"ref74","unstructured":"Van Alphen C, Ammeraal M, Blanke C, Boonstra N, Boumans H, et al.. (2012) Multidisciplinary guidelines schizophrenia (In Dutch: Multidiscipliniare richtlijn schizofrenie). Utrecht, Netherlands: De Tijdstroom."},{"key":"ref75","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/j.schres.2013.08.001","article-title":"Risk of symptom recurrence with medication discontinuation in first-episode psychosis: A systematic review","volume":"152","author":"RB Zipursky","year":"2014","journal-title":"Schizophr Res"},{"key":"ref76","doi-asserted-by":"crossref","first-page":"78","DOI":"10.9758\/cpn.2012.10.2.78","article-title":"Treatment response in first-episode schizophrenia","volume":"10","author":"R Schennach","year":"2012","journal-title":"Clin Psychopharmacol Neurosci"},{"key":"ref77","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1176\/appi.ajp.2009.09060802","article-title":"International consensus study of antipsychotic dosing","volume":"167","author":"DM Gardner","year":"2010","journal-title":"Am J Psychiatry"},{"key":"ref78","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1017\/S0033291711001656","article-title":"Cannabis and cognitive performance in psychosis: A cross-sectional study in patients with non-affective psychotic illness and their unaffected siblings","volume":"42","author":"JH Meijer","year":"2012","journal-title":"Psychol Med"},{"key":"ref79","doi-asserted-by":"crossref","first-page":"2529","DOI":"10.1038\/npp.2011.141","article-title":"AKT1 moderation of cannabis-induced cognitive alterations in psychotic disorder","volume":"36","author":"R Van Winkel","year":"2011","journal-title":"Neuropsychopharmacology"},{"key":"ref80","doi-asserted-by":"crossref","first-page":"5036","DOI":"10.2174\/138161212802884762","article-title":"Cannabis use in patients at clinical high risk of psychosis: Impact on prodromal symptoms and transition to psychosis","volume":"18","author":"FJ van der Meer","year":"2012","journal-title":"Curr Pharm Des"},{"key":"ref81","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1001\/archgenpsychiatry.2010.132","article-title":"Evidence that familial liability for psychosis is expressed as differential sensitivity to cannabis: An analysis of patient-sibling and sibling-control pairs","volume":"68","year":"2011","journal-title":"Arch Gen Psychiatry"},{"key":"ref82","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1093\/schbul\/sbn135","article-title":"Psychiatric comorbidities and schizophrenia","volume":"35","author":"PF Buckley","year":"2009","journal-title":"Schizophr Bull"},{"key":"ref83","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.eurpsy.2010.10.007","article-title":"The course of depressive symptoms and prescribing patterns of antidepressants in schizophrenia in a one-year follow-up study","volume":"27","author":"IM Lako","year":"2012","journal-title":"Eur Psychiatry"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0113521","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,9]],"date-time":"2020-05-09T00:47:54Z","timestamp":1588985274000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0113521"}},"subtitle":[],"editor":[{"given":"Kenji","family":"Hashimoto","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2014,11,20]]},"references-count":83,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2014,11,20]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0113521","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,11,20]]}}}