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Available: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.2.uol.com.br\/aprendiz\/n_noticias\/imprescindivel\/id150802.doc\" xlink:type=\"simple\">http\/\/www.2.uol.com.br\/aprendiz\/n_noticias\/imprescindivel\/id150802.doc<\/ext-link>. Accessed 28 April 2011."},{"key":"ref11","first-page":"8","article-title":"Boletim Epidemiol\u00f3gico AIDS e DST ano","volume":"VI(1)","author":"Brasil Minist\u00e9rio da Sa\u00fade do","year":"2010"},{"key":"ref12","first-page":"17","article-title":"Boletim Epidemiol\u00f3gico de AIDS, HIV\/DST e Hepatites B e C do Munic\u00edpio de S\u00e3o Paulo ano","volume":"XIV(13)","author":"Sa\u00fade Prefeitura da Cidade de S\u00e3o Paulo. Secretaria Municipal de","year":"2010"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1590\/S1415-790X1999000100009","article-title":"Tabulador de causas m\u00faltiplas de morte","volume":"2(1\/2)","author":"AH Santo","year":"1999","journal-title":"Rev Bras Epidemiol"},{"key":"ref14","first-page":"157","article-title":"Correspondencias entre CIE-10 y CIE-9 para las listas de causas de muerte Del Instituto Nacional de Estad\u00edstica y de la Regi\u00f3n de Murcia","volume":"80(2)","author":"LC Su\u00e1rez","year":"2006","journal-title":"Rev Esp Salud P\u00fablica"},{"key":"ref15","unstructured":"Minist\u00e9rio da Sa\u00fade do Brasil, Secretaria de Pol\u00edticas de Sa\u00fade, Coordena\u00e7\u00e3o Nacional de DST e Aids (2002) Vigil\u00e2ncia do HIV no Brasil - Novas Diretrizes. Bras\u00edlia: Minist\u00e9rio da Sa\u00fade. 82p. Available: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/bvsms.saude.gov.br\/bvs\/publicacoes\/162vig_hiv_005.pdf\" xlink:type=\"simple\">http:\/\/bvsms.saude.gov.br\/bvs\/publicacoes\/162vig_hiv_005.pdf<\/ext-link>. Accessed 20 November 2013."},{"key":"ref16","unstructured":"Minist\u00e9rio da Sa\u00fade do Brasil, Secretaria de Vigil\u00e2ncia em Sa\u00fade, Programa Nacional de DST e Aids (2004) Crit\u00e9rios de defini\u00e7\u00e3o de casos de AIDS em adultos e crian\u00e7as. Bras\u00edlia: Minist\u00e9rio da Sa\u00fade. 56p."},{"key":"ref17","first-page":"187","article-title":"Pesquisa pioneira recupera casos de Aids no Estado de S\u00e3o Paulo: integra\u00e7\u00e3o das bases do Sinan-Aids e da Funda\u00e7\u00e3o Seade","volume":"23(1)","author":"BC Waldvogel","year":"2006","journal-title":"Rev Bras Estud Popul"},{"key":"ref18","unstructured":"Waldvogel BC, Morais LCC, Guibu IA (2010) Base Integrada Paulista de Aids: recupera\u00e7\u00e3o, ger\u00eancia e vincula\u00e7\u00e3o de dados para melhoria da qualidade da informa\u00e7\u00e3o. In: Centro de Refer\u00eancia e Treinamento DST\/AIDS, Funda\u00e7\u00e3o SEADE. Dados para repensar a AIDS no estado de S\u00e3o Paulo: resultados da parceria entre Programa Estadual DST\/AIDS e Funda\u00e7\u00e3o SEADE. S\u00e3o Paulo: DST\/AIDS e Funda\u00e7\u00e3o Seade. pp.9\u201324."},{"key":"ref19","first-page":"5","article-title":"Espa\u00e7os e dimens\u00f5es da pobreza nos munic\u00edpios do Estado de S\u00e3o Paulo: \u00cdndice Paulista de Vulnerabilidade Social \u2013 IPVS","volume":"20(1)","author":"MP Ferreira","year":"2006","journal-title":"S\u00e3o Paulo em Perspectiva"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1111\/j.1468-1293.2005.00271.x","article-title":"Changing mortality rates and causes of death for HIV-infected individuals living in Southern Alberta, Canada from 1984 to 2003","volume":"6(2)","author":"HB Krentz","year":"2005","journal-title":"HIV Med"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1097\/01.qai.0000179459.31562.16","article-title":"Comparisons of causes of death and mortality rates among HIV-infected persons: analysis of the pre-, early, and late HAART (highly active antiretroviral therapy) eras","volume":"41(2)","author":"NF Crum","year":"2006","journal-title":"J Acquir Immune Defic Syndr"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"1862","DOI":"10.1016\/S0140-6736(02)11775-2","article-title":"Access to antiretroviral drugs in Brazil","volume":"360(9348)","author":"J Galv\u00e3o","year":"2002","journal-title":"Lancet"},{"key":"ref23","doi-asserted-by":"crossref","unstructured":"Hacker MA, Kaida A, Hogg RS, Bastos FI (2007) The first ten years: achievements and challenges of the Brazilian program of universal Access to HIV\/AIDS comprehensive management and care, 1996\u20132006. 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