{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T02:38:46Z","timestamp":1791340726503,"version":"4.3.1"},"reference-count":74,"publisher":"Public Library of Science (PLoS)","issue":"1","license":[{"start":{"date-parts":[[2015,1,21]],"date-time":"2015-01-21T00:00:00Z","timestamp":1421798400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0115516","type":"journal-article","created":{"date-parts":[[2015,1,21]],"date-time":"2015-01-21T19:58:35Z","timestamp":1421870315000},"page":"e0115516","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":28,"title":["Comparative Genomic and Phylogenetic Analyses of Gammaproteobacterial glg Genes Traced the Origin of the Escherichia coli Glycogen glgBXCAP Operon to the Last Common Ancestor of the Sister Orders Enterobacteriales and Pasteurellales"],"prefix":"10.1371","volume":"10","author":[{"given":"Goizeder","family":"Almagro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandro M.","family":"Viale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel","family":"Montero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehdi","family":"Rahimpour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco Jos\u00e9","family":"Mu\u00f1oz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edurne","family":"Baroja-Fern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdellatif","family":"Bahaji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel","family":"Z\u00fa\u00f1iga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"Gonz\u00e1lez-Candelas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"Pozueta-Romero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2015,1,21]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1038\/220606a0","article-title":"Bacterial \u2018glycogen\u2019 and survival","volume":"220","author":"RE Strange","year":"1968","journal-title":"Nature"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1128\/JB.101.3.1083-1085.1970","article-title":"Role of glycogen in survival of <italic>Streptococcus mitis<\/italic>","volume":"101","author":"J Van Houte","year":"1970","journal-title":"J Bacteriol"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/0378-1119(94)90869-9","article-title":"A chromosomal cluster of genes encoding ADP-glucose synthetase, glycogen synthase and phosphoglucomutase in <italic>Agrobacterium tumefaciens<\/italic>","volume":"150","author":"AD Uttaro","year":"1994","journal-title":"Gene"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"6557","DOI":"10.1128\/JB.180.24.6557-6564.1998","article-title":"Gene organization and transcription analysis of the <italic>Agrobacterium tumefaciens<\/italic> glycogen (<italic>glg<\/italic>) operon: two transcripts for the single phosphoglucomutase gene","volume":"180","author":"JE Ugalde","year":"1998","journal-title":"J Bacteriol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1111\/j.1365-2958.2008.06445.x","article-title":"Capsular glucan and intracellular glycogen of <italic>Mycobacterium tuberculosis<\/italic>: biosynthesis and impact on the persistence in mice","volume":"70","author":"T Sambou","year":"2008","journal-title":"Mol. Microbiol"},{"key":"ref6","doi-asserted-by":"crossref","DOI":"10.1128\/ecosalplus.4.7.4","article-title":"Glycogen: biosynthesis and regulation","author":"J Preiss","year":"2009"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1111\/j.1574-6976.2010.00220.x","article-title":"Regulation of glycogen metabolism in yeast and bacteria","volume":"34","author":"WA Wilson","year":"2010","journal-title":"FEMS Microbiol Rev"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1007\/s00114-011-0832-x","article-title":"Glycogen with short average chain length enhances bacterial durability","volume":"98","author":"L Wang","year":"2011","journal-title":"Naturwissenschaften"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"2118","DOI":"10.1021\/bm300497c","article-title":"Production of extracellular glycogen by <italic>Pseudomonas fluorescens<\/italic>: spectroscopic evidence and conformational analysis by biomolecular recognition","volume":"13","author":"F Quil\u00e8s","year":"2012","journal-title":"Biomacromolecules"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1111\/j.1574-6968.2000.tb09315.x","article-title":"The relationship between glycogen synthesis, biofilm formation and virulence in <italic>Salmonella enteritidis<\/italic>","volume":"191","author":"MA Bonafonte","year":"2000","journal-title":"FEMS Microbiol Lett"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1111\/j.1365-2958.2009.06629.x","article-title":"Glycogen contributes to the environmental persistence and transmission of <italic>Vibrio cholerae<\/italic>","volume":"72","author":"L Bourassa","year":"2009","journal-title":"Mol Microbiol"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"1565","DOI":"10.1099\/mic.0.044263-0","article-title":"Unexpected and widespread connections between bacterial glycogen and trehalose metabolism","volume":"157","author":"G Chandra","year":"2011","journal-title":"Microbiology"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"1442","DOI":"10.1016\/j.bbapap.2012.06.010","article-title":"Glycogen is the primary source of glucose during the lag phase of <italic>E. coli<\/italic> proliferation","volume":"1824","author":"T Yamamotoya","year":"2012","journal-title":"Biochim Biophys Acta"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.jbiotec.2013.04.005","article-title":"Natural osmolytes are much less effective substrates than glycogen for catabolic energy production in the marine cyanobacterium <italic>Synechococcus<\/italic> sp. strain PCC 7002","volume":"166","author":"LT Guerra","year":"2013","journal-title":"J Biotechnol"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"4635","DOI":"10.1128\/IAI.00975-13","article-title":"Analysis of the proteome of intracellular <italic>Shigella flexneri<\/italic> reveals pathways important for intracellular growth","volume":"81","author":"R Pieper","year":"2013","journal-title":"Infect Immun"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1128\/MMBR.67.2.213-225.2003","article-title":"ADP-glucose pyrophosphorylase, a regulatory enzyme for bacterial glycogen synthesis","volume":"67","author":"MA Ballicora","year":"2003","journal-title":"Microbiol Mol Biol Rev"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1128\/JB.187.4.1465-1473.2005","article-title":"Role of the <italic>Escherichia coli glgX<\/italic> gene in glycogen metabolism","volume":"187","author":"D Dauvill\u00e9e","year":"2005","journal-title":"J Bacteriol"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"5266","DOI":"10.1128\/JB.01566-05","article-title":"Glycogen phosphorylase, the product of the <italic>glgP<\/italic> gene, catalyzes glycogen breakdown by removing glucose units from the nonreducing ends in <italic>Escherichia coli<\/italic>","volume":"188","author":"N Alonso-Casajus","year":"2006","journal-title":"J Bacteriol"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"4417","DOI":"10.1016\/j.febslet.2007.08.016","article-title":"An <italic>Escherichia coli<\/italic> mutant producing a truncated inactive form of GlgC synthesizes glycogen: further evidences for the occurrence of various important sources of ADPglucose in enterobacteria","volume":"581","author":"G Eydallin","year":"2007","journal-title":"FEBS Lett"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"4423","DOI":"10.1016\/j.febslet.2007.08.017","article-title":"Occurrence of more than one important source of ADPglucose linked to glycogen biosynthesis in <italic>Escherichia coli<\/italic> and <italic>Salmonella enterica<\/italic>","volume":"581","author":"MT Mor\u00e1n-Zorzano","year":"2007","journal-title":"FEBS Lett"},{"key":"ref21","article-title":"GENES IV","author":"B Lewin","year":"1997"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/S0968-0004(98)01274-2","article-title":"Conservation of gene order: a fingerprint of proteins that physically interact","volume":"23","author":"T Dandekar","year":"1998","journal-title":"Trends Biochem Sci"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1016\/S0959-437X(99)00025-8","article-title":"Selfish operons: the evolutionary impact of gene clustering in prokaryotes and eukaryotes","volume":"9","author":"J Lawrence","year":"1999","journal-title":"Curr Opin Genet Dev"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1042\/BJ20101186","article-title":"<italic>Escherichia coli<\/italic> glycogen genes are organized in a single <italic>glgBXCAP<\/italic> transcriptional unit possessing an alternative suboperonic promoter within <italic>glgC<\/italic> that directs <italic>glgAP<\/italic> expression","volume":"433","author":"M Montero","year":"2011","journal-title":"Biochem. J"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"2305","DOI":"10.1128\/JB.01480-09","article-title":"Phylogeny of gammaproteobacteria","volume":"192","author":"KP Williams","year":"2010","journal-title":"J Bacteriol"},{"key":"ref26","article-title":"Taxonomic outline of the prokaryotes, Bergey\u00b4s manual of systematic bacteriology","author":"GM Garrity","year":"2005"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1186\/1741-7007-9-87","article-title":"Multiple origins of endosymbiosis within the <italic>Enterobacteriaceae<\/italic> (gamma-Proteobacteria): convergence of complex phylogenetic approaches","volume":"9","author":"F Husnik","year":"2011","journal-title":"BMC Biol"},{"key":"ref28","first-page":"275","article-title":"The rapid generation of mutation data matrices from protein sequences","volume":"8","author":"DT Jones","year":"1992","journal-title":"Comput Appl Biosci"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1099\/ijs.0.002741-0","article-title":"Phylogenomics and protein signatures elucidating the evolutionary relationships among the <italic>Gammaproteobacteria<\/italic>","volume":"59","author":"B Gao","year":"2009","journal-title":"Int J Syst Evol Microbiol"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1093\/bioinformatics\/bts118","article-title":"GOHTAM: a website for genomic origin of horizontal transfers, alignment and metagenomics","volume":"28","author":"S M\u00e9nigaud","year":"2012","journal-title":"Bioinformatics"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"S57","DOI":"10.1007\/PL00000052","article-title":"Genome plasticity as a paradigm of eubacteria evolution","volume":"44","author":"H Watanabe","year":"1997","journal-title":"J Mol Evol"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1093\/oxfordjournals.molbev.a026114","article-title":"Evolutionary instability of operon structures disclosed by sequence comparisons of complete microbial genomes","volume":"16","author":"T Itoh","year":"1999","journal-title":"Mol Biol Evol"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/S0168-9525(02)02734-8","article-title":"Glycogen metabolism loss: a common marker of parasitic behaviour in bacteria?","volume":"18","author":"B Henrissat","year":"2002","journal-title":"Trends Genet"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"7784","DOI":"10.1128\/jb.179.24.7784-7789.1997","article-title":"A <italic>glgC<\/italic> gene essential only for the first two spatially distinct phases of glycogen synthesis in <italic>Streptomyces coelicolor<\/italic>","volume":"179","author":"MC Martin","year":"1997","journal-title":"J Bacteriol"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1111\/j.1432-1033.1967.tb00117.x","article-title":"La maltodextrine phosphorylase d\u00b4<italic>Escherichia coli<\/italic>","volume":"1","author":"M Schwartz","year":"1967","journal-title":"Europ J Biochem"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/0003-9861(68)90213-0","article-title":"<italic>Escherichia coli<\/italic> polyglucose phosphorylases","volume":"127","author":"GS Chen","year":"1968","journal-title":"Arch Biochem Biophys"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"2517","DOI":"10.1128\/JB.01238-10","article-title":"Role of maltose enzymes in glycogen synthesis by <italic>Escherichia coli<\/italic>","volume":"193","author":"JT Park","year":"2011","journal-title":"J Bacteriol"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"e35707","DOI":"10.1371\/journal.pone.0035707","article-title":"<italic>Aeromonas<\/italic> surface glucan attached through the O-antigen ligase represents a new way to obtain UDP-glucose","volume":"7","author":"S Merino","year":"2012","journal-title":"PLoS One"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"1843","DOI":"10.1093\/genetics\/143.4.1843","article-title":"Selfish operons: horizontal transfer may drive the evolution of gene clusters","volume":"143","author":"JG Lawrence","year":"1996","journal-title":"Genetics"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1101\/SQB.1961.026.01.024","article-title":"On the regulation of gene activity","volume":"26","author":"F Jacob","year":"1961","journal-title":"Cold Spring Harb Symp Quant Biol"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/S0092-8674(02)00900-5","article-title":"Shared strategies in gene organization among prokaryotes and eukaryotes","volume":"110","author":"JG Lawrence","year":"2002","journal-title":"Cell"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1101\/gr.3368805","article-title":"Operon formation is driven by co-regulation and not by horizontal gene transfer","volume":"15","author":"MN Price","year":"2005","journal-title":"Genome Res"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"e96","DOI":"10.1371\/journal.pgen.0020096","article-title":"The life-cycle of operons","volume":"2","author":"MN Price","year":"2006","journal-title":"PLoS Genet"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1039\/b801245h","article-title":"Engineering stochasticity in gene expression","volume":"4","author":"JJ Tabor","year":"2008","journal-title":"Mol Biosyst"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"e00177","DOI":"10.1128\/mBio.00177-10","article-title":"Economy of operon formation: contranscription minimizes shortfall in protein complexes","volume":"1","author":"K Sneppen","year":"2010","journal-title":"MBio"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"2212","DOI":"10.1099\/mic.0.2006\/005181-0","article-title":"The <italic>glgX<\/italic> gene product of <italic>Corynebacterium glutamicum<\/italic> is required for glycogen degradation and for fast adaptation to hyperosmotic stress","volume":"153","author":"GM Seibold","year":"2007","journal-title":"Microbiology"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"6670","DOI":"10.1128\/JB.181.21.6670-6678.1999","article-title":"Exponential-phase glycogen recycling is essential for growth of <italic>Mycobacterium smegmatis<\/italic>","volume":"181","author":"AE Belanger","year":"1999","journal-title":"J. Bacteriol"},{"key":"ref48","first-page":"277","article-title":"Substrate cycles: their role in improving sensitivity in metabolic control","volume":"9","author":"EA Newsholme","year":"1984","journal-title":"TIBS"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/0005-2728(90)90260-B","article-title":"The role of futile cycles in the energetics of bacterial growth","volume":"1018","author":"OM Neijssel","year":"1990","journal-title":"Biochim Biophys Acta"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1093\/dnares\/dsp028","article-title":"Genome-wide screening of genes whose enhanced expression affects glycogen accumulation in <italic>Escherichia coli<\/italic>","volume":"17","author":"G Eydallin","year":"2010","journal-title":"DNA Res"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1042\/BJ20090980","article-title":"<italic>Escherichia coli<\/italic> glycogen metabolism is controlled by the PhoP-PhoQ regulatory system at submillimolar environmental Mg<sup>2+<\/sup> concentrations, and is highly interconnected with a wide variety of cellular processes","volume":"424","author":"M Montero","year":"2009","journal-title":"Biochem J"},{"key":"ref52","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1093\/nar\/gkg004","article-title":"HGT-DB: a database of putative horizontally transferred genes in prokaryotic complete genomes","volume":"31","author":"S Garc\u00eda-Vallv\u00e9","year":"2003","journal-title":"Nucleic Acids Res"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1038\/ng1381","article-title":"Biased biological functions of horizontally transferred genes in prokaryotic genomes","volume":"36","author":"Y Nakamura","year":"2004","journal-title":"Nat Genet"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1007\/PL00006158","article-title":"Amelioration of bacterial genomes: rates of change and exchange","volume":"44","author":"JG Lawrence","year":"1997","journal-title":"J Mol Evol"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"M5","DOI":"10.1016\/S0962-8924(99)01664-5","article-title":"Lateral genomics","volume":"9","author":"WF Doolittle","year":"1999","journal-title":"Trends Cell Biol"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"3801","DOI":"10.1073\/pnas.96.7.3801","article-title":"Horizontal gene transfer among genomes:The complexity hypothesis","volume":"96","author":"R Jain","year":"1999","journal-title":"Proc Natl Acad Sci USA"},{"key":"ref57","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/S0966-842X(00)01703-0","article-title":"Horizontal gene transfer and the origin of species: Lessons from bacteria","volume":"8","author":"F De la Cruz","year":"2000","journal-title":"Trends Microbiol"},{"key":"ref58","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1038\/35012500","article-title":"Lateral gene transfer and the nature of bacterial innovation","volume":"405","author":"H Ochman","year":"2000","journal-title":"Nature"},{"key":"ref59","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1006\/tpbi.2002.1587","article-title":"Gene transfer in bacteria: Speciation without species?","volume":"61","author":"JG Lawrence","year":"2002","journal-title":"Theor Popul Biol"},{"key":"ref60","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/S0022-2836(05)80360-2","article-title":"Basic local alignment search tool","volume":"215","author":"F Altschul","year":"1997","journal-title":"J Mol Biol"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"D169","DOI":"10.1093\/nar\/gkl889","article-title":"The ribosomal database project (RDP-II): introducing myRDP space and quality controlled public data","volume":"35","author":"JR Cole","year":"2007","journal-title":"Nucleic Acids Res"},{"key":"ref62","doi-asserted-by":"crossref","first-page":"4673","DOI":"10.1093\/nar\/22.22.4673","article-title":"CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice","volume":"22","author":"JD Thompson","year":"1994","journal-title":"Nucleic Acids Res"},{"key":"ref63","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1093\/oxfordjournals.molbev.a026334","article-title":"Selection of conserved blocks from multiple alignments for their use in phylogenetic analysis","volume":"17","author":"J Castresana","year":"2000","journal-title":"Mol Biol Evol"},{"key":"ref64","doi-asserted-by":"crossref","first-page":"2104","DOI":"10.1093\/bioinformatics\/bti263","article-title":"ProtTest: Selection of best-fit models of protein evolution","volume":"21","author":"F Abascal","year":"2005","journal-title":"Bioinformatics"},{"key":"ref65","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1109\/TAC.1974.1100705","article-title":"A new look at the statistical model identification","volume":"19","author":"H Akaike","year":"1974","journal-title":"IEEE Trans Automat Contr AC-"},{"key":"ref66","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1093\/molbev\/msn067","article-title":"An improved general amino acid replacement matrix","volume":"25","author":"SQ Le","year":"2008","journal-title":"Mol Biol Evol"},{"key":"ref67","doi-asserted-by":"crossref","first-page":"6815","DOI":"10.1073\/pnas.94.13.6815","article-title":"Likelihood-mapping: A simple method to visualize phylogenetic content of a sequence alignment","volume":"94","author":"K Strimmer","year":"1997","journal-title":"Proc Natl Acad Sci USA"},{"key":"ref68","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1093\/bioinformatics\/18.3.502","article-title":"TREE-PUZZLE: maximum likelihood phylogenetic analysis using quartets and parallel computing","volume":"18","author":"HA Schmidt","year":"2002","journal-title":"Bioinformatics"},{"key":"ref69","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1093\/sysbio\/syq010","article-title":"New Algorithms and Methods to Estimate Maximum-Likelihood Phylogenies: Assessing the Performance of PhyML 3.0","volume":"59","author":"S Guindon","year":"2010","journal-title":"Syst Biol"},{"key":"ref70","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1038\/nmeth.2109","article-title":"jModelTest 2: more models, new heuristics and parallel computing","volume":"9","author":"D Darriba","year":"2012","journal-title":"Nature Methods"},{"key":"ref71","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1093\/oxfordjournals.molbev.a026201","article-title":"Multiple comparisons of log-likelihoods with applications to phylogenetic inference","volume":"16","author":"H Shimodaira","year":"1999","journal-title":"Mol Biol Evol"},{"key":"ref72","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1093\/oxfordjournals.molbev.a026048","article-title":"Genomic signature: characterization and classification of species assessed by chaos game representation of sequences","volume":"16","author":"PJ Deschavanne","year":"1999","journal-title":"Mol Biol Evol"},{"key":"ref73","doi-asserted-by":"crossref","first-page":"e6","DOI":"10.1093\/nar\/gni004","article-title":"Detection and characterization of horizontal transfers in prokaryotes using genomic signature","volume":"33","author":"C Dufraigne","year":"2005","journal-title":"Nucleic Acids Res"},{"key":"ref74","doi-asserted-by":"crossref","first-page":"e9989","DOI":"10.1371\/journal.pone.0009989","article-title":"A benchmark of parametric methods for horizontal transfers detection","volume":"5","author":"J Becq","year":"2010","journal-title":"PLoS One"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0115516","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,27]],"date-time":"2022-04-27T05:02:47Z","timestamp":1651035767000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0115516"}},"subtitle":[],"editor":[{"given":"Gabriel","family":"Moreno-Hagelsieb","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2015,1,21]]},"references-count":74,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2015,1,21]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0115516","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,1,21]]}}}