{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T03:40:59Z","timestamp":1777434059420,"version":"3.51.4"},"reference-count":25,"publisher":"Public Library of Science (PLoS)","issue":"12","license":[{"start":{"date-parts":[[2014,12,30]],"date-time":"2014-12-30T00:00:00Z","timestamp":1419897600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0115792","type":"journal-article","created":{"date-parts":[[2014,12,30]],"date-time":"2014-12-30T18:53:45Z","timestamp":1419965625000},"page":"e115792","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":15,"title":["The Incidence of Sexually Dimorphic Gene Expression Varies Greatly between Tissues in the Rat"],"prefix":"10.1371","volume":"9","author":[{"given":"Russell D. J.","family":"Huby","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip","family":"Glaves","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Jackson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2014,12,30]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1161\/01.HYP.19.5.456","article-title":"Androgen-dependent angiotensinogen and renin messenger RNA expression in hypertensive rats","volume":"19","author":"YF Chen","year":"1992","journal-title":"Hypertension 19"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"9","DOI":"10.2131\/jts.36.9","article-title":"Sex and circadian modulatory effects on rat liver as assessed by transcriptome analyses","volume":"36","author":"J Hirao","year":"2011","journal-title":"J Toxicol Sci"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1007\/s00109-007-0240-z","article-title":"Sexually dimorphic gene expression in the heart of mice and men","volume":"86","author":"J Isensee","year":"2008","journal-title":"J Mol Med (Berl)"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1152\/physiolgenomics.00115.2011","article-title":"Detailed transcriptomics analysis of the effect of dietary fatty acids on gene expression in the heart","volume":"44","author":"A Georgiadi","year":"2012","journal-title":"Physiol Genomics"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"15605","DOI":"10.1073\/pnas.0806883105","article-title":"Gene expression changes in the course of normal brain aging are sexually dimorphic","volume":"105","author":"NC Berchtold","year":"2008","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1101\/gr.5217506","article-title":"Tissue-specific expression and regulation of sexually dimorphic genes in mice","volume":"16","author":"X Yang","year":"2006","journal-title":"Genome Res"},{"key":"ref7","doi-asserted-by":"crossref","unstructured":"Wu Z, Irizarry RA, Gentleman R, Martinez F, Spencer F (2004) A model based background adjustment for oligonucleotide expression arrays. Biochemistry: 1\u201327.","DOI":"10.1198\/016214504000000683"},{"key":"ref8","doi-asserted-by":"crossref","unstructured":"Ciaudo C, Bourdet A, Cohen-Tannoudji M, Dietz HC, Rougeulle C, et al. (2006) Nuclear mRNA degradation pathway(s) are implicated in xist regulation and X chromosome inactivation. PLoS Genet 2; 2: e94. Epub 2006 Jun 16.","DOI":"10.1371\/journal.pgen.0020094"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.1093\/hmg\/7.11.1725","article-title":"Characterization of genes encoding translation initiation factor eIF-2gamma in mouse and human: Sex chromosome localization, escape from X-inactivation and evolution","volume":"7","author":"IE Ehrmann","year":"1998","journal-title":"Hum Mol Genet 7"},{"key":"ref10","first-page":"111","article-title":"Statistical methods for identifying differentially expressed genes in replicated cDNA microarray experiments. Stat","volume":"12","author":"S Dudoit","year":"2002","journal-title":"Sin"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1016\/j.ygeno.2007.01.009","article-title":"Androgens drive divergent responses to salt stress in male versus female rat kidneys","volume":"89","author":"D Gerhold","year":"2007","journal-title":"Genomics"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"28988","DOI":"10.1074\/jbc.M710528200","article-title":"A feedback loop between the androgen receptor and a NEDD4-binding protein, PMEPA1, in prostate cancer cells","volume":"283","author":"H Li","year":"2008","journal-title":"J Biol Chem"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/0303-7207(94)90037-X","article-title":"Immunocytochemical localization of prolactin receptors in rat liver cells: I. dependence on sex and sex steroids","volume":"105","author":"OV Smirnova","year":"1994","journal-title":"Mol Cell Endocrinol"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1016\/j.neuroscience.2005.04.060","article-title":"Cell type-specific and sexually dimorphic expression of transcription factor AP-2 in adult mouse brain","volume":"134","author":"DJ Coelho","year":"2005","journal-title":"Neuroscience"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.modgep.2005.06.011","article-title":"Sexually dimorphic expression of the X-linked gene Eif2s3x mRNA but not protein in mouse brain","volume":"6","author":"J Xu","year":"2006","journal-title":"Gene Expr Patterns"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1038\/ng717","article-title":"A Y-encoded subunit of the translation initiation factor Eif2 is essential for mouse spermatogenesis","volume":"29","author":"S Mazeyrat","year":"2001","journal-title":"Nat Genet"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1007\/s00005-011-0124-3","article-title":"Gender specific differences in the immune response to infection","volume":"59","author":"EE McClelland","year":"2011","journal-title":"Arch Immunol Ther Exp (Warsz)"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.2174\/156652409789839116","article-title":"Sexual dimorphism in autoimmune disease","volume":"9","author":"PA McCombe","year":"2009","journal-title":"Curr Mol Med"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.tem.2003.11.001","article-title":"Are XX and XY brain cells intrinsically different?","volume":"15","author":"AP Arnold","year":"2004","journal-title":"Trends Endocrinol Metab 15"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1038\/427390a","article-title":"Brain development: The most important sexual organ","volume":"427","author":"C Dennis","year":"2004","journal-title":"Nature 427"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1126\/science.1233521","article-title":"Sex differences in the gut microbiome drive hormone-dependent regulation of autoimmunity","volume":"339","author":"JG Markle","year":"2013","journal-title":"Science"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"508","DOI":"10.2174\/138920009788898000","article-title":"Transcriptional regulation of cytochrome p450 genes by the nuclear receptor hepatocyte nuclear factor 4-alpha","volume":"10","author":"R Jover","year":"2009","journal-title":"Curr Drug Metab"},{"key":"ref23","doi-asserted-by":"crossref","unstructured":"Mode A, Ahlgren R, Lahuna O, Gustafsson JA (1998) Gender differences in rat hepatic CYP2C gene expression\u2013regulation by growth hormone. Growth Horm IGF Res 8 Suppl B: 61\u201367.","DOI":"10.1016\/S1096-6374(98)80025-7"},{"key":"ref24","doi-asserted-by":"crossref","unstructured":"Laz EV, Wiwi CA, Waxman DJ (2004) Sexual dimorphism of rat liver nuclear proteins: Regulatory role of growth hormone. Mol Cell Proteomics 3; 3: 1170\u20131180; Epub 2004 Sep 29.","DOI":"10.1074\/mcp.M400102-MCP200"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"1962","DOI":"10.1210\/me.2007-0549","article-title":"Sex-specific early growth hormone response genes in rat liver","volume":"22","author":"V Wauthier","year":"2008","journal-title":"Mol Endocrinol"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0115792","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,9]],"date-time":"2020-05-09T05:47:04Z","timestamp":1589003224000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0115792"}},"subtitle":[],"editor":[{"given":"Gualtiero I.","family":"Colombo","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2014,12,30]]},"references-count":25,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2014,12,30]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0115792","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,12,30]]}}}