{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T10:04:16Z","timestamp":1785751456809,"version":"3.56.0"},"reference-count":30,"publisher":"Public Library of Science (PLoS)","issue":"12","license":[{"start":{"date-parts":[[2014,12,30]],"date-time":"2014-12-30T00:00:00Z","timestamp":1419897600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0116295","type":"journal-article","created":{"date-parts":[[2014,12,30]],"date-time":"2014-12-30T18:59:46Z","timestamp":1419965986000},"page":"e116295","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":30,"title":["Inflammatory Micro-Environmental Cues of Human Atherothrombotic Arteries Confer to Vascular Smooth Muscle Cells the Capacity to Trigger Lymphoid Neogenesis"],"prefix":"10.1371","volume":"9","author":[{"given":"Kevin","family":"Guedj","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamila","family":"Khallou-Laschet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Clement","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marion","family":"Morvan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandrine","family":"Delbosc","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anh-Thu","family":"Gaston","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Andreata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yves","family":"Castier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Deschildre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Baptiste","family":"Michel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppina","family":"Caligiuri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonino","family":"Nicoletti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2014,12,30]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1876","DOI":"10.1161\/hq1201.100220","article-title":"Immune mechanisms in atherosclerosis","volume":"21","author":"GK Hansson","year":"2001","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1038\/nri1786","article-title":"Lymphoid neogenesis in chronic inflammatory diseases","volume":"6","author":"F Aloisi","year":"2006","journal-title":"Nat Rev Immunol"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1002\/1096-9896(2000)9999:9999<::AID-PATH774>3.0.CO;2-N","article-title":"Adventitial infiltrates associated with advanced atherosclerotic plaques: structural organization suggests generation of local humoral immune responses","volume":"193","author":"MA Houtkamp","year":"2001","journal-title":"J Pathol"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1084\/jem.20080752","article-title":"Lymphotoxin beta receptor signaling promotes tertiary lymphoid organogenesis in the aorta adventitia of aged ApoE\u2212\/\u2212 mice","volume":"206","author":"R Grabner","year":"2009","journal-title":"J Exp Med"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"e89983","DOI":"10.1371\/journal.pone.0089983","article-title":"Deciphering the stromal and hematopoietic cell network of the adventitia from non-aneurysmal and aneurysmal human aorta","volume":"9","author":"CA Dutertre","year":"2014","journal-title":"PLoS One"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1038\/ni1330","article-title":"Lymphoid organ development: from ontogeny to neogenesis","volume":"7","author":"DL Drayton","year":"2006","journal-title":"Nat Immunol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1161\/ATVBAHA.106.137851","article-title":"Topological determinants and consequences of adventitial responses to arterial wall injury","volume":"27","author":"JB Michel","year":"2007","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"717","DOI":"10.4049\/jimmunol.0903589","article-title":"Chronic rejection triggers the development of an aggressive intragraft immune response through recapitulation of lymphoid organogenesis","volume":"185","author":"O Thaunat","year":"2010","journal-title":"J Immunol"},{"key":"ref9","doi-asserted-by":"crossref","unstructured":"Guedj K, Khallou-Laschet J, Clement M, Morvan M, Gaston AT, et al. (2013) M1 macrophages act as LTbetaR-independent lymphoid tissue inducer cells during atherosclerosis-related lymphoid neogenesis. Cardiovasc Res.","DOI":"10.1093\/cvr\/cvt263"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1161\/ATVBAHA.109.191395","article-title":"Mouse aorta smooth muscle cells differentiate into lymphoid tissue organizer-like cells on combined tumor necrosis factor receptor-1\/lymphotoxin beta-receptor NF-kappaB signaling","volume":"30","author":"K Lotzer","year":"2010","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1111\/j.1600-6143.2004.00714.x","article-title":"Lymphoid neogenesis in murine cardiac allografts undergoing chronic rejection","volume":"5","author":"FK Baddoura","year":"2005","journal-title":"Am J Transplant"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/1471-2172-6-6","article-title":"A HEV-restricted sulfotransferase is expressed in rheumatoid arthritis synovium and is induced by lymphotoxin-alpha\/beta and TNF-alpha in cultured endothelial cells","volume":"6","author":"JL Pablos","year":"2005","journal-title":"BMC Immunol"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1002\/art.1780310405","article-title":"Spirochetal antigens and lymphoid cell surface markers in Lyme synovitis. Comparison with rheumatoid synovium and tonsillar lymphoid tissue","volume":"31","author":"AC Steere","year":"1988","journal-title":"Arthritis Rheum"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1172\/JCI3234","article-title":"Antigen-driven clonal proliferation of B cells within the target tissue of an autoimmune disease. The salivary glands of patients with Sjogren\u2019s syndrome","volume":"102","author":"DI Stott","year":"1998","journal-title":"J Clin Invest"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1136\/hrt.18.2.166","article-title":"The significance of adventitial infiltrations in coronary atherosclerosis","volume":"18","author":"LM Gerlis","year":"1956","journal-title":"Brit Heart J"},{"key":"ref16","first-page":"418","article-title":"Evidence for an inflammatory basis of coronary arteriosclerosis in the young","volume":"49","author":"O Saphir","year":"1950","journal-title":"Arch Pathol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1093\/cvr\/cvt263","article-title":"M1 macrophages act as LTbetaR-independent lymphoid tissue inducer cells during atherosclerosis-related lymphoid neogenesis","volume":"101","author":"K Guedj","year":"2014","journal-title":"Cardiovasc Res"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"7464","DOI":"10.1073\/pnas.97.13.7464","article-title":"Both early and delayed anti-CD40L antibody treatment induces a stable plaque phenotype","volume":"97","author":"E Lutgens","year":"2000","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.cytogfr.2008.11.003","article-title":"Interferon gamma: a master regulator of atherosclerosis","volume":"20","author":"JE McLaren","year":"2009","journal-title":"Cytokine Growth Factor Rev"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1161\/01.ATV.0000064374.15232.C3","article-title":"Lack of interleukin-1beta decreases the severity of atherosclerosis in ApoE-deficient mice","volume":"23","author":"H Kirii","year":"2003","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"2137","DOI":"10.1161\/01.ATV.0000143933.20616.1b","article-title":"Inhibition of tumor necrosis factor-alpha reduces atherosclerosis in apolipoprotein E knockout mice","volume":"24","author":"L Branen","year":"2004","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"5820","DOI":"10.4049\/jimmunol.1000116","article-title":"A critical function of Th17 proinflammatory cells in the development of atherosclerotic plaque in mice","volume":"185","author":"Q Gao","year":"2010","journal-title":"J Immunol"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1016\/j.jaci.2005.10.046","article-title":"IL-31 is associated with cutaneous lymphocyte antigen-positive skin homing T cells in patients with atopic dermatitis","volume":"117","author":"J Bilsborough","year":"2006","journal-title":"J Allergy Clin Immunol"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1007\/s12015-012-9364-9","article-title":"IL1beta induces mesenchymal stem cells migration and leucocyte chemotaxis through NF-kappaB","volume":"8","author":"R Carrero","year":"2012","journal-title":"Stem Cell Rev"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1111\/j.1365-2249.2007.03398.x","article-title":"CXC chemokine ligand 16 in periodontal diseases: expression in diseased tissues and production by cytokine-stimulated human gingival fibroblasts","volume":"149","author":"Y Hosokawa","year":"2007","journal-title":"Clin Exp Immunol"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1002\/art.30232","article-title":"Characterization of CCL19 and CCL21 in rheumatoid arthritis","volume":"63","author":"SR Pickens","year":"2011","journal-title":"Arthritis Rheum"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"253","DOI":"10.4049\/jimmunol.178.1.253","article-title":"Multiple NF-kappaB and IFN regulatory factor family transcription factors regulate CCL19 gene expression in human monocyte-derived dendritic cells","volume":"178","author":"TE Pietila","year":"2007","journal-title":"J Immunol"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1038\/jid.2012.260","article-title":"CCR6 is required for epidermal trafficking of gammadelta-T cells in an IL-23-induced model of psoriasiform dermatitis","volume":"133","author":"T Mabuchi","year":"2013","journal-title":"J Invest Dermatol"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"4479","DOI":"10.4049\/jimmunol.0901942","article-title":"IL-17-mediated monocyte migration occurs partially through CC chemokine ligand 2\/monocyte chemoattractant protein-1 induction","volume":"184","author":"S Shahrara","year":"2010","journal-title":"J Immunol"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"e45","DOI":"10.1093\/nar\/29.9.e45","article-title":"A new mathematical model for relative quantification in real-time RT-PCR","volume":"29","author":"MW Pfaffl","year":"2001","journal-title":"Nucleic Acids Res"}],"container-title":["PLoS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0116295","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,19]],"date-time":"2019-08-19T03:00:31Z","timestamp":1566183631000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0116295"}},"subtitle":[],"editor":[{"given":"Liwu","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2014,12,30]]},"references-count":30,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2014,12,30]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0116295","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,12,30]]}}}