{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T23:25:41Z","timestamp":1792711541246,"version":"4.5.0"},"reference-count":78,"publisher":"Public Library of Science (PLoS)","issue":"3","license":[{"start":{"date-parts":[[2015,3,18]],"date-time":"2015-03-18T00:00:00Z","timestamp":1426636800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/publicdomain\/zero\/1.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0118748","type":"journal-article","created":{"date-parts":[[2015,3,18]],"date-time":"2015-03-18T20:33:05Z","timestamp":1426710785000},"page":"e0118748","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":162,"title":["Assessment of Chronic Sublethal Effects of Imidacloprid on Honey Bee Colony Health"],"prefix":"10.1371","volume":"10","author":[{"given":"Galen P.","family":"Dively","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael S.","family":"Embrey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alaa","family":"Kamel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J.","family":"Hawthorne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffery S.","family":"Pettis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2015,3,18]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1080\/0005772X.2002.11099532","article-title":"Honey bee winter mortality in France in 1999 and 2000","volume":"83","author":"JP Faucon","year":"2002","journal-title":"Bee World"},{"key":"ref2","article-title":"Status of pollinators in North America","year":"2007"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1126\/science.1127863","article-title":"Parallel declines in pollinators and insect-pollinated plants in Britain and the Netherlands","volume":"313","author":"JC Biesmeijer","year":"2006","journal-title":"Science"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.jip.2009.06.011","article-title":"A historical review of managed honey bee populations in Europe and the United States and the factors that may affect them","volume":"103","author":"D VanEngelsdorp","year":"2010","journal-title":"J Invert Pathol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.tree.2010.01.007","article-title":"Global pollinator declines: trends, impacts and drivers","volume":"25","author":"SG Potts","year":"2010","journal-title":"Trends Ecol Evol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1073\/pnas.1014743108","article-title":"Patterns of widespread decline in North American bumble bees","volume":"108","author":"SA Cameron","year":"2010","journal-title":"PNAS"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"100","DOI":"10.3896\/IBRA.1.51.1.12","article-title":"Managed honey bee colony losses in Canada, China, Europe, Israel and Turkey, for the winters of 2008\u20139 and 2009\u201310","volume":"51","author":"R van der Zee","year":"2012","journal-title":"J Apic Res"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"7","DOI":"10.3896\/IBRA.1.49.1.03","article-title":"A survey of honey bee colony losses in the United States, fall 2008 to spring 2009","volume":"49","author":"D vanEngelsdorp","year":"2010","journal-title":"J Apic Res"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"115","DOI":"10.3896\/IBRA.1.51.1.14","article-title":"A national survey of managed honey bee 2010\u201311 winter colony losses in the USA: results from the Bee Informed Partnership","volume":"51","author":"D vanEngelsdorp","year":"2012","journal-title":"J. Api Res"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"44","DOI":"10.3896\/IBRA.1.52.2.07","article-title":"A national survey of managed honey bee 2011\u201312 winter colony losses in the United States: results from the Bee Informed Partnership","volume":"52","author":"AM Spleen","year":"2013","journal-title":"J Apic Res"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1126\/science.314.5798.397","article-title":"Ecology: report warns of looming pollination crisis in North America","volume":"314","author":"C Holden","year":"2006","journal-title":"Science"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1016\/j.ecolecon.2008.06.014","article-title":"Economic valuation of the vulnerability of world agriculture confronted with pollinator decline","volume":"68","author":"N Gallai","year":"2009","journal-title":"Ecological Economics"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"e168","DOI":"10.1371\/journal.pbio.0050168","article-title":"What\u2019s killing American honey bees?","volume":"5","author":"BP Oldroyd","year":"2007","journal-title":"PLOS Biol"},{"issue":"8","key":"ref14","doi-asserted-by":"crossref","first-page":"e6481","DOI":"10.1371\/journal.pone.0006481","article-title":"Colony collapse disorder: a descriptive study","volume":"4","author":"D vanEngelsdorp","year":"2009","journal-title":"PLOS ONE"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1603\/EC09429","article-title":"Weighing risk factors associated with bee colony collapse disorder by classification and regression tree analysis","volume":"103","author":"D vanEngelsdorp","year":"2010","journal-title":"J. Econ. Entomol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1016\/j.jip.2009.06.011","article-title":"A historical review of managed honey bee populations in Europe and the United States and the factors that may affect them","volume":"103","author":"D vanEngelsdorp","year":"2010","journal-title":"J. Invert. Pathol"},{"issue":"8","key":"ref17","doi-asserted-by":"crossref","first-page":"e43562","DOI":"10.1371\/journal.pone.0043562","article-title":"Pathogen webs in collapsing honey bee colonies","volume":"7","author":"RS Cornman","year":"2012","journal-title":"PLOS ONE"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"1964","DOI":"10.1603\/EC10235","article-title":"Overview of pesticide residues in stored pollen and their potential effect on bee colony (<italic>Apis mellifera<\/italic>) losses in Spain","volume":"103","author":"J Bernal","year":"2010","journal-title":"J Econ Entomol"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1603\/022.038.0302","article-title":"Influence of pesticide residues on honey bee (Hymenoptera: Apidae) colony health in France","volume":"38","author":"MP Chauzat","year":"2009","journal-title":"Environ Entomol"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1051\/apido\/2010014","article-title":"The German bee monitoring project: a long term study to understand periodically high winter losses of honey bee colonies","volume":"41","author":"E Genersch","year":"2010","journal-title":"Apidologie"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"e9754","DOI":"10.1371\/journal.pone.0009754","article-title":"High levels of miticides and agrochemicals in North American apiaries: implications for honey bee health","volume":"5","author":"CA Mullin","year":"2010","journal-title":"PLOS ONE"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1051\/apido\/2010018","article-title":"Pesticides and honey bee toxicity\u2014USA","volume":"41","author":"RM Johnson","year":"2010","journal-title":"Apidologie"},{"key":"ref23","first-page":"779","article-title":"Pesticides and their involvement in Colony Collapse Disorder","author":"JL Frazier","year":"2011","journal-title":"Amer Bee J"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"e70182","DOI":"10.1371\/journal.pone.0070182","article-title":"Crop Pollination Exposes honey bees to pesticides which alters their susceptibility to the gut pathogen <italic>Nosema ceranae<\/italic>","volume":"8","author":"JS Pettis","year":"2013","journal-title":"PLOS ONE"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1603\/029.102.0202","article-title":"Synergistic interactions between in-hive miticides in <italic>Apis mellifera<\/italic>","volume":"102","author":"RM Johnson","year":"2009","journal-title":"J. Econ. Entomol"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"2897","DOI":"10.1021\/jf101303g","article-title":"Overview of the status and global strategy for neonicotinoids","volume":"59","author":"P Jeschke","year":"2011","journal-title":"J Agric Food Chem"},{"key":"ref27","first-page":"172","article-title":"New Discoveries in Agrochemicals: American Chemical Society Symposium Series","author":"K Matsuda","year":"2005"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1002\/ps.331","article-title":"Toxicity and nicotinic acetylcholine receptor interaction of imidacloprid and its metabolites in <italic>Apis mellifera<\/italic> (Hymenoptera: Apidae)","volume":"57","author":"R Nauen","year":"2001","journal-title":"Pest Manag Sci"},{"key":"ref29","first-page":"1123","article-title":"Handbook of Pesticide Toxicology","author":"LP Sheets","year":"2001"},{"key":"ref30","doi-asserted-by":"crossref","DOI":"10.1002\/9780470946404","article-title":"Fine Chemicals: The Industry and the Business","author":"P Pollak","year":"2011"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1002\/ps.1616","article-title":"Applied aspects of neonicotinoid uses in crop protection","volume":"64","author":"A Elbert","year":"2008","journal-title":"Pest Manag Sci"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"8005","DOI":"10.1021\/jf034310n","article-title":"Distribution of [C-14]imidacloprid in sunflowers (<italic>Helianthus annuus<\/italic> L.) following seed treatment","volume":"51","author":"FM Laurent","year":"2003","journal-title":"J Agric Food Chem"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1603\/0022-0493(2007)100[765:ETCSCH]2.0.CO;2","article-title":"Exposure to clothianidin seed treated canola has no long-term impact on honey bees","volume":"100","author":"GC Cutler","year":"2007","journal-title":"J Econ Entomol"},{"issue":"6","key":"ref34","doi-asserted-by":"crossref","first-page":"e39114","DOI":"10.1371\/journal.pone.0039114","article-title":"Movement of soil-applied imidacloprid and thiamethoxam into nectar and pollen of squash (<italic>Cucurbita pepo<\/italic>)","volume":"7","author":"KA Stoner","year":"2012","journal-title":"PLOS ONE"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"4449","DOI":"10.1021\/jf205393x","article-title":"Insecticide residues in pollen and nectar of a cucurbit crop and their potential exposure to pollinators","volume":"60","author":"GP Dively","year":"2012","journal-title":"J Agric Food Chem"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1002\/ps.3290","article-title":"Dietary traces of neonicotinoid pesticides as a cause of population declines in honey bees: an evaluation by Hill&apos;s epidemiological criteria","volume":"68","author":"JE Cresswell","year":"2012","journal-title":"Pest Manag Sci"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1080\/10807039.2013.831263","article-title":"A causal analysis of observed declines in managed honey bees (<italic>Apis mellifera<\/italic>)","volume":"20","author":"JP Staveley","year":"2014","journal-title":"Hum and Ecol Risk Assess"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1007\/s10646-012-0863-x","article-title":"Neonicotinoids in bees: a review on concentrations, side-effects and risk assessment","volume":"21","author":"T Blacqui\u00e8re","year":"2012","journal-title":"Ecotoxicology"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1051\/apido\/2010018","article-title":"Pesticides and honey bee toxicity\u2014USA","volume":"41","author":"RM Johnson","year":"2010","journal-title":"Apidologie"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1111\/1365-2664.12111","article-title":"An overview of the environmental risks posed by neonicotinoid insecticides","volume":"50","author":"D Goulson","year":"2013","journal-title":"J Appl Ecol"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1002\/ps.270","article-title":"Risk posed to honeybees (<italic>Apis mellifera<\/italic> L. Hymenoptera) by an imidacloprid seed dressing of sunflowers","volume":"57","author":"R Schmuck","year":"2001","journal-title":"Pest Manag Sci"},{"key":"ref42","first-page":"29","article-title":"Systemic insecticides: new risk for pollinator insects","volume":"62","author":"R Charvet","year":"2004","journal-title":"Ann Pharm Fr"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"2027","DOI":"10.1021\/ac020600b","article-title":"A LC\/APCI-MS\/MS method for analysis of imidacloprid in soils, in plants, and in pollens","volume":"75","author":"JM Bonmatin","year":"2003","journal-title":"Anal Chem"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1007\/s00128-011-0515-5","article-title":"Detections of the neonicotinoid insecticide imidacloprid in surface waters of three agricultural regions of California, USA, 2010\u20132011","volume":"88","author":"K Starner","year":"2012","journal-title":"Bull Environ Contam Toxicol"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"1808","DOI":"10.1603\/029.102.0511","article-title":"Translocation of neonicotinoid insecticides from coated seeds to seedling guttation drops: a novel way of intoxication for bees","volume":"102","author":"V Girolami","year":"2009","journal-title":"J Econ Entomol"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"1564","DOI":"10.1039\/c1em10085h","article-title":"Rapid analysis of neonicotinoid insecticides in guttation drops of corn seedlings obtained from coated seeds","volume":"13","author":"A Tapparo","year":"2011","journal-title":"J Environ Monit"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"e29268","DOI":"10.1371\/journal.pone.0029268","article-title":"Multiple routes of pesticide exposure for honey bees living near agricultural fields","volume":"7","author":"CH Krupke","year":"2012","journal-title":"PLOS ONE"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1093\/jee\/99.2.253","article-title":"Survey of pesticide residues in pollen loads collected by honey bees in France","volume":"99","author":"MP Chauzat","year":"2006","journal-title":"J. Econ. Entomol"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1002\/etc.361","article-title":"An assessment of honeybee colony matrices, <italic>Apis mellifera<\/italic> (Hymenoptera: Apidae) to monitor pesticide presence in continental France","volume":"30","author":"MP Chauzat","year":"2011","journal-title":"Environ Toxicol Chem"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1603\/029.102.0220","article-title":"Does imidacloprid seed-treated maize have an impact on honey bee mortality?","volume":"102","author":"BK Nguyen","year":"2009","journal-title":"J Econ Entomol"},{"key":"ref51","first-page":"51","article-title":"Safety of imidacloprid seed dressings to honey bees: a comprehensive overview and compilation of the current state of knowledge","volume":"56","author":"C Maus","year":"2003","journal-title":"Bull Insectol"},{"key":"ref52","first-page":"85","article-title":"Insect nicotinic acetylcholine receptors","author":"A Decourtye","year":"2010"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1146\/annurev.ento.52.110405.091440","article-title":"The sublethal effects of pesticides on beneficial arthropods","volume":"52","author":"N Desneux","year":"2007","journal-title":"Ann Rev Entomol"},{"key":"ref54","article-title":"Effects of neonicotinoids and fipronil on non-target invertebrates","author":"L Pisa","year":"2014","journal-title":"Environ Sci Pollut Res"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0026796","article-title":"Killing them with kindness? In-hive medications may inhibit xenobiotic efflux transporters and endanger honey bees","volume":"6","author":"DJ Hawthorne","year":"2011","journal-title":"PLOS ONE"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1007\/s00114-011-0881-1","article-title":"Pesticide exposure in honey bees results in increased levels of the gut pathogen Nosema","volume":"99","author":"JS Pettis","year":"2012","journal-title":"Naturwissenschaften"},{"key":"ref57","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1002\/ps.957","article-title":"Experimental study on the toxicity of imidacloprid given in syrup to honey bee (<italic>Apis mellifera<\/italic>) colonies","volume":"61","author":"P Faucon J-","year":"2005","journal-title":"Pest Manag Sci"},{"key":"ref58","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1007\/s10646-010-0566-0","article-title":"A meta-analysis of experiments testing the effects of a neonicotinoid insecticide (imidacloprid) on honey bees","volume":"20","author":"JE Cresswell","year":"2010","journal-title":"Ecotoxicology"},{"key":"ref59","first-page":"115","article-title":"Residues of neonicotinoid insecticides in bee collected plant materials from oilseed rape crops and their effect on bee colonies","volume":"56","author":"K Pohorecka","year":"2012","journal-title":"J Apic Sci"},{"key":"ref60","doi-asserted-by":"crossref","first-page":"e77193","DOI":"10.1371\/journal.pone.0077193","article-title":"A four-year field program investigating long-term effects of repeated exposure of honey bee colonies to flowering crops treated with thiamethoxam","volume":"8","author":"E Pilling","year":"2013","journal-title":"PLOS ONE"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1126\/science.1215039","article-title":"A common pesticide decreases foraging success and survival in honey bees","volume":"336","author":"M Henry","year":"2012","journal-title":"Science"},{"key":"ref62","first-page":"99","article-title":"<italic>In situ<\/italic> replication of honey bee colony collapse disorder","volume":"65","author":"C Lu","year":"2012","journal-title":"Bull Insectol"},{"key":"ref63","doi-asserted-by":"crossref","first-page":"e103592","DOI":"10.1371\/journal.pone.0103592","article-title":"Impact of chronic neonicotinoid exposure on honeybee colony performance and queen supersedure","volume":"9","author":"C Sandrock","year":"2014","journal-title":"PLOS ONE"},{"key":"ref64","doi-asserted-by":"crossref","first-page":"5926","DOI":"10.1021\/jf904120n","article-title":"Refined methodology for the determination of neonicotinoid pesticides and their metabolites in honey bees and bee products by liquid chromatography-tandem mass spectrometry (LC-MS\/MS)","volume":"58","author":"A Kamel","year":"2010","journal-title":"J. Agric. Food Chem"},{"key":"ref65","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1051\/apido:2007022","article-title":"Effects of Bt corn pollen on honey bees: emphasis on protocol development","volume":"38","author":"RI Rose","year":"2007","journal-title":"Apidologie"},{"key":"ref66","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1080\/00218839.2008.11101473","article-title":"Comparisons of pollen substitute diets for honey bees: consumption rates by colonies and effects on brood and adult populations","volume":"47","author":"G DeGrandi-Hoffman","year":"2008","journal-title":"J Apic Res and Bee World"},{"key":"ref67","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1016\/j.jinsphys.2010.03.017","article-title":"The effect of diet on protein concentration, hypopharyngeal gland development and virus load in worker honey bees (<italic>Apis mellifera<\/italic> L.)","volume":"56","author":"G DeGrandi-Hoffman","year":"2010","journal-title":"J of Insect Physiol"},{"key":"ref68","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1051\/apido:2005015","article-title":"Differences in drone and worker physiology in honeybees (<italic>Apis mellifera<\/italic> L.)","volume":"36","author":"N Hrassnigg","year":"2005","journal-title":"Apidologie"},{"key":"ref69","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1051\/apido:2004071","article-title":"Modes of honeybees exposure to systemic insecticides: estimated amounts of contaminated pollen and nectar consumed by different categories of bees","volume":"36","author":"A Rortais","year":"2005","journal-title":"Apidologie"},{"key":"ref70","unstructured":"Kunkel GR. In vitro measures of mdr-transporter function and whole hive exposure dynamics using fluorescent dyes. MSc. Thesis, University of Maryland. 2014. Available: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/search.proquest.com\/docview\/1625416115\" xlink:type=\"simple\">http:\/\/search.proquest.com\/docview\/1625416115<\/ext-link>."},{"key":"ref71","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1002\/ps.772","article-title":"Metabolism of imidacloprid in <italic>Apis mellifera<\/italic>","volume":"60","author":"S Suchail","year":"2004","journal-title":"Pest Manag Sci"},{"key":"ref72","doi-asserted-by":"crossref","first-page":"e30023","DOI":"10.1371\/journal.pone.0030023","article-title":"RFID tracking of sublethal effects of two neonicotinoid insecticides on the foraging behavior of <italic>Apis mellifera<\/italic>","volume":"7","author":"CW Schneider","year":"2012","journal-title":"PLOS ONE"},{"key":"ref73","first-page":"63","article-title":"Effect of sub-lethal imidacloprid doses on the homing rate and foraging activity of honey bees","volume":"56","author":"L Bortolotti","year":"2003","journal-title":"Bull Insectol"},{"key":"ref74","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1007\/s10646-014-1189-7","article-title":"Field realistic doses of pesticide imidacloprid reduce bumblebee pollen foraging efficiency","volume":"23","author":"H Feltham","year":"2014","journal-title":"Ecotoxicology"},{"key":"ref75","doi-asserted-by":"crossref","first-page":"18466","DOI":"10.1073\/pnas.1314923110","article-title":"Neonicotinoid clothianidin adversely affects insect immunity and promotes replication of a viral pathogen in honey bees","volume":"110","author":"G Di Prisco","year":"2013","journal-title":"Proc Natl Acad Sci USA"},{"key":"ref76","doi-asserted-by":"crossref","unstructured":"Rondeau G, S\u00e1nchez-Bayo F, Tennekes HA, Decourtye A, Ram\u00edrez-Romero R, Desneux N. Delayed and time-cumulative toxicity of imidacloprid in bees, ants and termites. Scientific Reports. 2014;4 (article 5566).","DOI":"10.1038\/srep05566"},{"key":"ref77","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1126\/science.1259159","article-title":"The trouble with neonicotinoids","volume":"346","author":"F S\u00e1nchez-Bayo","year":"2014","journal-title":"Science"},{"key":"ref78","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1038\/497188a","article-title":"Overhaul pesticide testing on bees","volume":"497","author":"A Decourtye","year":"2013","journal-title":"Nature"}],"updated-by":[{"DOI":"10.1371\/journal.pone.0181297","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2017,7,7]],"date-time":"2017-07-07T00:00:00Z","timestamp":1499385600000}},{"DOI":"10.1371\/journal.pone.0126043","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2015,4,24]],"date-time":"2015-04-24T00:00:00Z","timestamp":1429833600000}}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0118748","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,9]],"date-time":"2020-05-09T14:13:14Z","timestamp":1589033594000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0118748"}},"subtitle":[],"editor":[{"given":"Nicolas","family":"Desneux","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2015,3,18]]},"references-count":78,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2015,3,18]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0118748","relation":{"correction":[{"id-type":"doi","id":"10.1371\/journal.pone.0126043","asserted-by":"object"},{"id-type":"doi","id":"10.1371\/journal.pone.0181297","asserted-by":"object"}]},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,3,18]]}}}