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Reduces Bovine Mastitis Associated with <italic>Chlamydophila<\/italic> Infection","volume":"75","author":"C Biesenkamp-Uhe","year":"2007","journal-title":"Infect Immun"},{"key":"ref74","unstructured":"EMEA (2000) Committee for Veterinary Medicinal Products Erythromycin Summary Report (2), (EMEA\/MRL\/720\/99-FINAL). In: Products TEAftEoM, Unit VMaIT. European Medicines Agency website. Available: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.ema.europa.eu\/docs\/en_GB\/document_library\/Maximum_Residue_Limits_-_Report\/2009\/11\/WC500014184.pdf\" xlink:type=\"simple\">http:\/\/www.ema.europa.eu\/docs\/en_GB\/document_library\/Maximum_Residue_Limits_-_Report\/2009\/11\/WC500014184.pdf<\/ext-link>. Accessed 2015 February 7."},{"key":"ref75","first-page":"e51557","article-title":"The bovine lung in biomedical research: visually guided bronchoscopy, intrabronchial inoculation and <italic>in vivo<\/italic> sampling techniques","volume":"89","author":"A Prohl","year":"2014","journal-title":"J Vis Exp"},{"key":"ref76","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1128\/JB.59.4.509-522.1950","article-title":"The influence of certain salts, amino acids, sugars and proteins on the stability of rickettsiae","author":"MRMJ Bovarnick","year":"1950","journal-title":"J Bact"},{"key":"ref77","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.mcp.2005.09.003","article-title":"Optimized DNA microarray assay allows detection and genotyping of single PCR-amplifiable target copies","volume":"20","author":"R Ehricht","year":"2006","journal-title":"Mol Cell Probes"},{"key":"ref78","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.tvjl.2008.02.025","article-title":"New real-time PCR tests for species-specific detection of <italic>Chlamydophila psittaci<\/italic> and <italic>Chlamydophila abortus<\/italic> from tissue samples","volume":"181","author":"A Pantchev","year":"2009","journal-title":"Vet J"},{"key":"ref79","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1186\/1471-2180-8-63","article-title":"Genotyping of <italic>Chlamydophila psittaci<\/italic> using a new DNA microarray assay based on sequence analysis of <italic>ompA<\/italic> genes","volume":"8","author":"K Sachse","year":"2008","journal-title":"BMC Microbiol"},{"key":"ref80","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.aca.2008.11.006","article-title":"Simple and rapid determination of enrofloxacin and ciprofloxacin in edible tissues by turbulent flow chromatography\/tandem mass spectrometry (TFC-MS\/MS)","volume":"637","author":"R Krebber","year":"2009","journal-title":"Anal Chim Acta"},{"key":"ref81","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/0378-1135(89)90035-7","article-title":"Comparative analysis of monoclonal antibodies against pestiviruses: report of an international workshop","volume":"20","author":"B Cay","year":"1989","journal-title":"Vet Microbiol"},{"key":"ref82","unstructured":"EMEA (1998) Committee for Veterinary Medicinal Products Enrofloxacin (modification for bovine, porcine and poultry) Summary Report (2), (EMEA\/MRL\/388\/98-FINAL). In: Products TEAftEoM, Unit VMaIT. European Medicines Agency website. Available: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.ema.europa.eu\/docs\/en_GB\/document_library\/Maximum_Residue_Limits_-_Report\/2009\/11\/WC500014142.pdf\" xlink:type=\"simple\">http:\/\/www.ema.europa.eu\/docs\/en_GB\/document_library\/Maximum_Residue_Limits_-_Report\/2009\/11\/WC500014142.pdf<\/ext-link>. Accessed 2015 February 7."},{"key":"ref83","article-title":"R: A language and environment for statistical computing","year":"2011"},{"key":"ref84","first-page":"8","article-title":"Plotrix: a package in the red light district of R","volume":"6","author":"J Lemon","year":"2006","journal-title":"R-News"},{"key":"ref85","first-page":"1","article-title":"nparcomp: An R Software Package for Nonparametric Multiple Comparisons and Simultaneous Confidence Intervals","volume":"61","author":"F Konietschke","year":"2014","journal-title":"J Stat Softw"},{"key":"ref86","doi-asserted-by":"crossref","first-page":"1","DOI":"10.18637\/jss.v028.i08","article-title":"Implementing a Class of Permutation Tests: The coin Package","volume":"28","author":"T Hothorn","year":"2008","journal-title":"J Stat Softw"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0119736","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,20]],"date-time":"2025-05-20T19:40:24Z","timestamp":1747770024000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0119736"}},"subtitle":[],"editor":[{"given":"Garry Stewart Anthony","family":"Myers","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2015,3,13]]},"references-count":86,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2015,3,13]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0119736","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,3,13]]}}}