{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T23:15:53Z","timestamp":1782774953053,"version":"3.54.5"},"reference-count":27,"publisher":"Public Library of Science (PLoS)","issue":"3","license":[{"start":{"date-parts":[[2015,3,17]],"date-time":"2015-03-17T00:00:00Z","timestamp":1426550400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0120502","type":"journal-article","created":{"date-parts":[[2015,3,17]],"date-time":"2015-03-17T15:51:18Z","timestamp":1426607478000},"page":"e0120502","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":60,"title":["Viridans Group Streptococci Clinical Isolates: MALDI-TOF Mass Spectrometry versus Gene Sequence-Based Identification"],"prefix":"10.1371","volume":"10","author":[{"given":"Silvia","family":"Angeletti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giordano","family":"Dicuonzo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandra","family":"Avola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Crea","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Etleva","family":"Dedej","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Vailati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudio","family":"Farina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucia","family":"De Florio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2015,3,17]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"3829","DOI":"10.1128\/JCM.01563-10","article-title":"It\u2019s not easy being green: the viridans group streptococci, with a focus on pediatric clinical manifestations","volume":"48","author":"CD Doern","year":"2010","journal-title":"J Clin Microbiol"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.ijantimicag.2008.06.023","article-title":"Incorrect identification of <italic>Streptococcus pneumoniae<\/italic> and its effect on antimicrobial resistance rates","volume":"33","author":"H Song J-","year":"2009","journal-title":"Int J Antimicrob Agents"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1161\/CIRCULATIONAHA.112.095281","article-title":"Incidence of Infective Endocarditis due to Viridans Group Streptococci Before and After Publication of the 2007 American Heart Association\u2019s Endocarditis Prevention Guidelines","volume":"126","author":"DC Desimone","year":"2012","journal-title":"Circulation"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1007\/s10096-010-1076-y","article-title":"Identification of clinically relevant viridans group streptococci by phenotypic and genotypic analysis","volume":"30","author":"C Teles","year":"2011","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1128\/CMR.15.4.613-630.2002","article-title":"What happened to the streptococci: overview of taxo- nomic and nomenclature changes","volume":"15","author":"R Facklam","year":"2002","journal-title":"Clin Microbiol Rev"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"4686","DOI":"10.1128\/JCM.42.10.4686-4696.2004","article-title":"Accuracy of phenotypic and genotypic testing for identification of <italic>Streptococcus pneumoniae<\/italic> and description of <italic>Streptococcus pseudopneumoniae<\/italic> sp. nov","volume":"42","author":"JC Arbique","year":"2004","journal-title":"J Clin Microbiol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"3686","DOI":"10.1128\/JCM.42.8.3686-3695.2004","article-title":"Use of <italic>tuf<\/italic> sequences for genus-specific PCR detection and phylogenetic analysis of 28 streptococcal species","volume":"42","author":"FJ Picard","year":"2004","journal-title":"J Clin Microbiol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"6073","DOI":"10.1128\/JCM.43.12.6073-6085.2005","article-title":"Use of phylogenetic and phenotypic analyses to identify nonhemolytic streptococci isolated from bacteremic patients","volume":"43","author":"T Hoshino","year":"2005","journal-title":"J Clin Microbiol"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1128\/JCM.06609-11","article-title":"Evaluation of several biochemical and molecular techniques for identification of <italic>Streptococcus pneumoniae<\/italic> and <italic>Streptococcus pseudopneumoniae<\/italic> and their detection in respiratory samples","volume":"50","author":"E Wessels","year":"2012","journal-title":"J Clin Microbiol"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.1128\/JCM.42.3.1360-1362.2004","article-title":"Development of a diagnostic PCR assay targeting the mn-dependent superoxide dismutase gene (<italic>sodA<\/italic>) for identification of <italic>Streptococcus gallolyticus<\/italic>","volume":"42","author":"E Sasaki","year":"2004","journal-title":"J Clin Microbiol"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"2460","DOI":"10.1128\/JCM.02498-06","article-title":"Evaluation and improvement of real-time PCR assays targeting <italic>lytA<\/italic>, <italic>ply<\/italic>, and <italic>psaA<\/italic> genes for detection of pneumococcal DNA","volume":"45","author":"MG Carvalho","year":"2007","journal-title":"J Clin Microbiol"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"3373","DOI":"10.1128\/JCM.39.9.3373-3375.2001","article-title":"Identification of <italic>Streptococcus pneumoniae<\/italic> Revisited","volume":"39","author":"JA Kellogg","year":"2001","journal-title":"J Clin Microbiol"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"2980","DOI":"10.1128\/JCM.00431-11","article-title":"Utility of matrix-assisted laser desorption ionization-time of flight mass spectrometry following introduction for routine laboratory bacterial identification","volume":"49","author":"SA Neville","year":"2011","journal-title":"J Clin Microbiol"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1128\/JCM.01794-09","article-title":"Performance of matrix-assisted laser desorption ionization-time of tlight mass spectrometry for identification of bacterial strains routinely isolated in a clinical microbiology laboratory","volume":"48","author":"A Bizzini","year":"2010","journal-title":"J Clin Microbiol"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1007\/s10096-013-2012-8","article-title":"Evaluation of two matrix-assisted laser desorption ionization-time of flight mass spectrometry systems for identification of viridans group streptococci","volume":"33","author":"P Karpanoja","year":"2014","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"2392","DOI":"10.1128\/JCM.00556-07","article-title":"Rapid identification of viridans streptococci by mass spectrometric discrimination","volume":"45","author":"C Friedrichs","year":"2007","journal-title":"J Clin Microbiol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.ijmm.2010.06.002","article-title":"MALDI-TOF MS fingerprinting allows for discrimination of major methicillin-resistant <italic>Staphylococcus aureus<\/italic> lineages","volume":"301","author":"M Wolters","year":"2011","journal-title":"Int J Med Microbiol"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1111\/j.1469-0691.2012.03837.x","article-title":"Value of matrix-assisted laser desorption ionization-time of flight for routine identification of viridans group streptococci causing bloodstream infections","volume":"19","author":"P Lopez Roa","year":"2012","journal-title":"Clin Microbiol Infect"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.diagmicrobio.2004.04.013","article-title":"Comparison of four polymerase chain reaction assays for specificity in the identification of <italic>Streptococcus pneumoniae<\/italic>","volume":"49","author":"TO Messmer","year":"2004","journal-title":"Diagn Microbiol Infect Dis"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1128\/JCM.03196-13","article-title":"Detection of extended-spectrum-\u03b2-lactamase-producing <italic>Escherichia coli<\/italic> ST131 and ST405 clonal groups by matrix-assisted laser desorption ionization-time of flight mass spectrometry","volume":"52","author":"Y Matsumura","year":"2014","journal-title":"J Clin Microbiol"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1128\/JCM.42.2.497-504.2004","article-title":"<italic>rpoB<\/italic> gene sequence-based identification of aerobic Gram-positive cocci of the genera <italic>Streptococcus<\/italic>, <italic>Enterococcus<\/italic>, <italic>Gemella<\/italic>, <italic>Abiotrophia<\/italic>, and <italic>Granulicatella<\/italic>","volume":"42","author":"M Drancourt","year":"2004","journal-title":"J Clin Microbiol"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1128\/JCM.06438-11","article-title":"Oral streptococcal bacteremia in hospitalized patients: taxonomic identification and clinical characterization","volume":"50","author":"T Kitten","year":"2012","journal-title":"J Clin Microbiol"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"762","DOI":"10.3201\/eid2005.130953","article-title":"<italic>Streptococcus mitis<\/italic> strains causing severe clinical disease in cancer patients","volume":"20","author":"SA Shelburne","year":"2014","journal-title":"Emerg Infect Dis"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1097\/01.inf.0000164708.21464.03","article-title":"Viridans streptococci bacteremia in children with malignancy: relevance of species identification and penicillin susceptibility","volume":"24","author":"E Husain","year":"2005","journal-title":"Pediatr Infect Dis J"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"2605","DOI":"10.1099\/00221287-145-9-2605","article-title":"Genetic approaches to the identification of the mitis group within the genus <italic>Streptococcus<\/italic>","volume":"145","author":"Y Kawamura","year":"1999","journal-title":"Microbiology"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"2905","DOI":"10.1128\/JCM.01068-14","article-title":"<italic>GyrB<\/italic> Polymorphisms Accurately Assign Invasive Viridans Group Streptococcal Species","volume":"52","author":"J Galloway-Pena","year":"2014","journal-title":"J Clin Microbiol"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"67","DOI":"10.12688\/f1000research.2-67.v1","article-title":"Streptococcal taxonomy based on genome sequence analyses","volume":"2","author":"CC Thompson","year":"2013","journal-title":"F1000Res"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0120502","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,21]],"date-time":"2019-08-21T22:53:11Z","timestamp":1566427991000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0120502"}},"subtitle":[],"editor":[{"given":"Jonathan Hon-Kwan","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2015,3,17]]},"references-count":27,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2015,3,17]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0120502","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,3,17]]}}}