{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T18:39:58Z","timestamp":1793299198562,"version":"4.5.0"},"reference-count":54,"publisher":"Public Library of Science (PLoS)","issue":"3","license":[{"start":{"date-parts":[[2015,3,24]],"date-time":"2015-03-24T00:00:00Z","timestamp":1427155200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0120986","type":"journal-article","created":{"date-parts":[[2015,3,24]],"date-time":"2015-03-24T20:11:35Z","timestamp":1427227895000},"page":"e0120986","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":67,"title":["Association between Tooth Loss and Cognitive Function among 3063 Chinese Older Adults: A Community-Based Study"],"prefix":"10.1371","volume":"10","author":[{"given":"Jianfeng","family":"Luo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bei","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qianhua","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qihao","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haijiao","family":"Meng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lirong","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen","family":"Hong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ding","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2015,3,24]]},"reference":[{"key":"ref1","article-title":"Population Division. World population prospects: the 2006 revision","year":"2007"},{"issue":"4","key":"ref2","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1002\/ana.410270412","article-title":"The prevalence of dementia and Alzheimer's disease in Shanghai, China: impact of age, gender, and education","volume":"27","author":"MY Zhang","year":"1990","journal-title":"Ann Neurol"},{"issue":"3","key":"ref3","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1001\/archneur.62.3.447","article-title":"Dementia subtypes in China: prevalence in Beijing, Xian, Shanghai, and Chengdu","volume":"62","author":"ZX Zhang","year":"2005","journal-title":"Arch Neurol"},{"issue":"9882","key":"ref4","doi-asserted-by":"crossref","first-page":"2016","DOI":"10.1016\/S0140-6736(13)60221-4","article-title":"Epidemiology of Alzheimer's disease and other forms of dementia in China, 1990\u20132010: a systematic review and analysis","volume":"381","author":"KY Chan","year":"2013","journal-title":"Lancet"},{"issue":"2","key":"ref5","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1001\/archneur.60.2.161","article-title":"Apolipoprotein E, Alzheimer disease, and African Americans","volume":"60","author":"R Mayeux","year":"2003","journal-title":"Arch Neurol"},{"issue":"3","key":"ref6","doi-asserted-by":"crossref","first-page":"139","DOI":"10.25100\/cm.v44i3.1248","article-title":"Self-reported tooth loss and cognitive function: Data from the Hispanic Established Populations for Epidemiologic Studies of the Elderly (Hispanic EPESE)","volume":"44","author":"CA Reyes-Ortiz","year":"2013","journal-title":"Colomb Med (Cali)"},{"issue":"9","key":"ref7","doi-asserted-by":"crossref","first-page":"1410","DOI":"10.1111\/j.1532-5415.2007.01298.x","article-title":"Dental health and cognitive impairment in an English national survey population","volume":"55","author":"R Stewart","year":"2007","journal-title":"J Am Geriatr Soc"},{"issue":"8","key":"ref8","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1097\/PSY.0b013e3181870aec","article-title":"Oral health and cognitive function in the Third National Health and Nutrition Examination Survey (NHANES III)","volume":"70","author":"R Stewart","year":"2008","journal-title":"Psychosom Med"},{"issue":"2","key":"ref9","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1111\/jgs.12094","article-title":"Adverse oral health and cognitive decline: the health, aging and body composition study","volume":"61","author":"R Stewart","year":"2013","journal-title":"J Am Geriatr Soc"},{"issue":"10","key":"ref10","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.14219\/jada.archive.2007.0046","article-title":"Tooth loss, dementia and neuropathology in the Nun study","volume":"138","author":"PS Stein","year":"2007","journal-title":"J Am Dent Assoc"},{"issue":"4","key":"ref11","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1111\/j.1532-5415.2010.02788.x","article-title":"Tooth loss and periodontal disease predict poor cognitive function in older men","volume":"58","author":"EK Kaye","year":"2010","journal-title":"J Am Geriatr Soc"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1186\/1744-9081-6-77","article-title":"Relationship of tooth loss to mild memory impairment and cognitive impairment: findings from the Fujiwara-kyo study","volume":"6","author":"N Okamoto","year":"2010","journal-title":"Behav Brain Funct"},{"issue":"3","key":"ref13","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1111\/j.1752-7325.2007.00038.x","article-title":"Dental service utilization among urban and rural older adults in China\u2014a brief communication","volume":"67","author":"B Wu","year":"2007","journal-title":"J Public Health Dent"},{"issue":"12","key":"ref14","doi-asserted-by":"crossref","first-page":"2216","DOI":"10.2105\/AJPH.2007.109934","article-title":"Cognitive function and dental care utilization among community-dwelling older adults","volume":"97","author":"B Wu","year":"2007","journal-title":"Am J Public Health"},{"issue":"2","key":"ref15","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1159\/000366163","article-title":"The shanghai aging study: study design, baseline characteristics, and prevalence of dementia","volume":"43","author":"D Ding","year":"2014","journal-title":"Neuroepidemiology"},{"key":"ref16","unstructured":"World Health Organization. BMI Classification. Global Database on Body Mass Index. Geneva2006. Retrieved July 27, 2012."},{"issue":"6","key":"ref17","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/S0033-3182(71)71479-0","article-title":"A rating instrument for anxiety disorders","volume":"12","author":"WW Zung","year":"1971","journal-title":"Psychosomatics"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1186\/1471-2288-11-74","article-title":"Measurement invariance of the Center for Epidemiological Studies Depression Scale (CES-D) among Chinese and Dutch elderly","volume":"11","author":"B Zhang","year":"2011","journal-title":"BMC Med Res Methodol"},{"issue":"24","key":"ref19","first-page":"4368","article-title":"Effect of anxiety and depression on the recurrence of persistent atrial fibrillation after circumferential pulmonary vein ablation","volume":"125","author":"SB Yu","year":"2012","journal-title":"Chin Med J (Engl)"},{"issue":"1","key":"ref20","doi-asserted-by":"crossref","first-page":"61","DOI":"10.3121\/cmr.2007.693","article-title":"Utility of the clinical dementia rating in Asian populations","volume":"5","author":"WS Lim","year":"2007","journal-title":"Clin Med Res"},{"issue":"11","key":"ref21","doi-asserted-by":"crossref","first-page":"2412","DOI":"10.1212\/WNL.43.11.2412-a","article-title":"The Clinical Dementia Rating (CDR): current version and scoring rules","volume":"43","author":"JC Morris","year":"1993","journal-title":"Neurology"},{"issue":"3","key":"ref22","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1093\/geront\/9.3_Part_1.179","article-title":"Assessment of older people: self-maintaining and instrumental activities of daily living","volume":"9","author":"MP Lawton","year":"1969","journal-title":"Gerontologist"},{"key":"ref23","article-title":"Prevalence of mild cognitive impairment in an urban community in China: a cross-sectional analysis of the Shanghai Aging Study","author":"D Ding","year":"2014"},{"key":"ref24","article-title":"Diagnostic and Statistical Manual of Mental Disorders","author":"AP Association","year":"1994"},{"issue":"3","key":"ref25","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1111\/j.1365-2796.2004.01388.x","article-title":"Mild cognitive impairment as a diagnostic entity","volume":"256","author":"RC Petersen","year":"2004","journal-title":"J Intern Med"},{"issue":"7246","key":"ref26","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1038\/nature07940","article-title":"Genetic analysis of radiation-induced changes in human gene expression","volume":"459","author":"DA Smirnov","year":"2009","journal-title":"Nature"},{"issue":"9","key":"ref27","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.1111\/j.1532-5415.2005.53468.x","article-title":"Systemic inflammatory markers, periodontal diseases, and periodontal infections in an elderly population","volume":"53","author":"WA Bretz","year":"2005","journal-title":"J Am Geriatr Soc"},{"issue":"4","key":"ref28","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1177\/10454411900010040601","article-title":"Systemic humoral immune responses in periodontal disease","volume":"1","author":"JL Ebersole","year":"1990","journal-title":"Crit Rev Oral Biol Med"},{"issue":"2","key":"ref29","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1111\/j.1365-2249.1997.270-ce1162.x","article-title":"Systemic acute-phase reactants, C-reactive protein and haptoglobin, in adult periodontitis","volume":"107","author":"JL Ebersole","year":"1997","journal-title":"Clin Exp Immunol"},{"issue":"11 Suppl","key":"ref30","doi-asserted-by":"crossref","first-page":"2106","DOI":"10.1902\/jop.2005.76.11-S.2106","article-title":"Systemic markers of inflammation in periodontitis","volume":"76","author":"BG Loos","year":"2005","journal-title":"J Periodontol"},{"issue":"9","key":"ref31","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1902\/jop.2000.72.9.1221","article-title":"Periodontal infections contribute to elevated systemic C-reactive protein level","volume":"72","author":"B Noack","year":"2001","journal-title":"J Periodontol"},{"issue":"3","key":"ref32","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/S0002-8177(88)73017-2","article-title":"Brain abscess from chronic odontogenic cause: report of case","volume":"117","author":"CJ Saal","year":"1988","journal-title":"J Am Dent Assoc"},{"issue":"4","key":"ref33","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1902\/jop.1990.61.4.243","article-title":"Parietal lobe abscess after routine periodontal recall therapy. Report of a case","volume":"61","author":"WC Andersen","year":"1990","journal-title":"J Periodontol"},{"issue":"3","key":"ref34","first-page":"224","article-title":"Brain abscess secondary to dental infection","volume":"38","author":"M Andrews","year":"1990","journal-title":"Gen Dent"},{"key":"ref35","first-page":"c49","article-title":"Brain abscess secondary to a dental infection in an 11-year-old child: case report","volume":"78","author":"CE Hibberd","year":"2012","journal-title":"J Can Dent Assoc"},{"issue":"3","key":"ref36","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1093\/ajcn\/82.3.627","article-title":"High homocysteine and low B vitamins predict cognitive decline in aging men: the Veterans Affairs Normative Aging Study","volume":"82","author":"KL Tucker","year":"2005","journal-title":"Am J Clin Nutr"},{"issue":"2","key":"ref37","doi-asserted-by":"crossref","first-page":"191","DOI":"10.14219\/jada.archive.1999.0168","article-title":"Alzheimer's disease, dental amalgam and mercury","volume":"130","author":"SR Saxe","year":"1999","journal-title":"J Am Dent Assoc"},{"issue":"2","key":"ref38","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1046\/j.0902-0055.2001.00100.x","article-title":"Molecular and immunological evidence of oral Treponema in the human brain and their association with Alzheimer's disease","volume":"17","author":"GR Riviere","year":"2002","journal-title":"Oral Microbiol Immunol"},{"issue":"2","key":"ref39","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1111\/j.1752-7325.2002.tb03432.x","article-title":"Validation of self-reported oral health measures","volume":"62","author":"W Pitiphat","year":"2002","journal-title":"J Public Health Dent"},{"issue":"2","key":"ref40","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1177\/0898264310382135","article-title":"Differences in self-reported oral health among community-dwelling black, Hispanic, and white elders","volume":"23","author":"B Wu","year":"2011","journal-title":"J Aging Health"},{"issue":"1","key":"ref41","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.eurpsy.2011.07.005","article-title":"Oral disease in relation to future risk of dementia and cognitive decline: prospective cohort study based on the Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified-Release Controlled Evaluation (ADVANCE) trial","volume":"28","author":"GD Batty","year":"2013","journal-title":"Eur Psychiatry"},{"issue":"2","key":"ref42","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.jalz.2006.01.002","article-title":"Potentially modifiable risk factors for dementia in identical twins","volume":"2","author":"M Gatz","year":"2006","journal-title":"Alzheimers Dement"},{"issue":"8","key":"ref43","doi-asserted-by":"crossref","first-page":"1556","DOI":"10.1111\/j.1532-5415.2012.04064.x","article-title":"Dentition, dental health habits, and dementia: the Leisure World Cohort Study","volume":"60","author":"A Paganini-Hill","year":"2012","journal-title":"J Am Geriatr Soc"},{"issue":"3","key":"ref44","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1097\/PSY.0b013e318246dffb","article-title":"Association between self-reported dental health status and onset of dementia: a 4-year prospective cohort study of older Japanese adults from the Aichi Gerontological Evaluation Study (AGES) Project","volume":"74","author":"T Yamamoto","year":"2012","journal-title":"Psychosom Med"},{"issue":"4","key":"ref45","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1111\/j.1752-7325.1991.tb02218.x","article-title":"The validity of self-reported oral health status in the elderly","volume":"51","author":"CW Douglass","year":"1991","journal-title":"J Public Health Dent"},{"key":"ref46","first-page":"6","article-title":"The reliability of self-assessment of number of remaining teeth using questionnaires [in Japanese]","volume":"47","author":"Y Ando","year":"1997","journal-title":"J Dent Health"},{"issue":"6","key":"ref47","first-page":"561","article-title":"The sampling survey of teeth defect and denture restoration among 1579 middle aged and elder people in Shanghai","volume":"18","author":"H Cheng","year":"2009","journal-title":"Shanghai Journal of Stomatology"},{"issue":"3","key":"ref48","first-page":"263","article-title":"Research Report of Common Oral Diseases of 800Old People in Jing\u2019an District,Shangha","volume":"10","author":"M-y Yang","year":"2001","journal-title":"Shanghai Journal of Stomatology"},{"issue":"9","key":"ref49","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1002\/gps.1750","article-title":"Dental health, nutritional status and recent-onset dementia in a Korean community population","volume":"22","author":"JM Kim","year":"2007","journal-title":"Int J Geriatr Psychiatry"},{"issue":"10","key":"ref50","doi-asserted-by":"crossref","first-page":"1951","DOI":"10.1111\/j.1532-5415.2012.04154.x","article-title":"Chewing ability and tooth loss: association with cognitive impairment in an elderly population study","volume":"60","author":"D Lexomboon","year":"2012","journal-title":"J Am Geriatr Soc"},{"issue":"1","key":"ref51","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/1744-859X-12-20","article-title":"Cognitive function and number of teeth in a community-dwelling population in Japan","volume":"12","author":"Y Saito","year":"2013","journal-title":"Ann Gen Psychiatry"},{"issue":"7","key":"ref52","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1111\/j.1600-051X.2009.01426.x","article-title":"Tooth loss and cognitive impairment","volume":"36","author":"HJ Grabe","year":"2009","journal-title":"J Clin Periodontol"},{"issue":"248","key":"ref53","first-page":"1","article-title":"Trends in oral health status: United States, 1988\u20131994 and 1999\u20132004","volume":"2007","author":"BA Dye","journal-title":"Vital Health Stat 11"},{"issue":"6","key":"ref54","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1902\/jop.2004.75.6.782","article-title":"Relationship of periodontal disease and tooth loss to prevalence of coronary heart disease","volume":"75","author":"JR Elter","year":"2004","journal-title":"J Periodontol"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0120986","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,31]],"date-time":"2020-08-31T04:20:08Z","timestamp":1598847608000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0120986"}},"subtitle":[],"editor":[{"given":"Kimon","family":"Divaris","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2015,3,24]]},"references-count":54,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2015,3,24]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0120986","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,3,24]]}}}