{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T10:35:50Z","timestamp":1792665350002,"version":"4.5.0"},"reference-count":79,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2015,4,7]],"date-time":"2015-04-07T00:00:00Z","timestamp":1428364800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0122762","type":"journal-article","created":{"date-parts":[[2015,4,7]],"date-time":"2015-04-07T18:48:00Z","timestamp":1428432480000},"page":"e0122762","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":30,"title":["Features of Two New Proteins with OmpA-Like Domains Identified in the Genome Sequences of Leptospira interrogans"],"prefix":"10.1371","volume":"10","author":[{"given":"Aline F.","family":"Teixeira","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zenaide M.","family":"de Morais","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karin","family":"Kirchgatter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eliete C.","family":"Romero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvio A.","family":"Vasconcellos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Lucia T. O.","family":"Nascimento","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2015,4,7]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1128\/CMR.14.2.296-326.2001","article-title":"Leptospirosis","volume":"14","author":"PN Levett","year":"2001","journal-title":"Clin Microbiol Rev"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1086\/346208","article-title":"Usefulness of serologic analysis as a predictor of the infecting serovar in patients with severe leptospirosis","volume":"36","author":"PN Levett","year":"2003","journal-title":"Clin Infect Dis"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1016\/S1473-3099(03)00830-2","article-title":"Leptospirosis: a zoonotic disease of global importance","volume":"3","author":"AR Bharti","year":"2003","journal-title":"Lancet Infect Dis"},{"key":"ref4","article-title":"Leptospira and Leptospirosis","author":"S Faine","year":"1999"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1128\/JCM.41.2.803-809.2003","article-title":"Evaluation of four commercially available rapid serologic tests for diagnosis of leptospirosis","volume":"41","author":"MD Bajani","year":"2003","journal-title":"J Clin Microbiol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"1853","DOI":"10.1128\/JCM.44.5.1853-1855.2006","article-title":"Evaluation of a commercial latex agglutination assay for serological diagnosis of leptospirosis","volume":"44","author":"C Hull-Jackson","year":"2006","journal-title":"J Clin Microbiol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1590\/S0100-879X2004000400003","article-title":"Genome features of Leptospira interrogans serovar Copenhageni","volume":"37","author":"AL Nascimento","year":"2004","journal-title":"Braz J Med Biol Res"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"2164","DOI":"10.1128\/JB.186.7.2164-2172.2004","article-title":"Comparative genomics of two Leptospira interrogans serovars reveals novel insights into physiology and pathogenesis","volume":"186","author":"AL Nascimento","year":"2004","journal-title":"J Bacteriol"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1111\/1574-6968.12349","article-title":"Leptospiral extracellular matrix adhesins as mediators of pathogen-host interactions","volume":"352","author":"ML Vieira","year":"2014","journal-title":"FEMS Microbiol Lett"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"e11259","DOI":"10.1371\/journal.pone.0011259","article-title":"In vitro identification of novel plasminogen-binding receptors of the pathogen Leptospira interrogans","volume":"5","author":"ML Vieira","year":"2010","journal-title":"PLoS One"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1016\/j.micpath.2011.06.008","article-title":"In vitro evidence for immune evasion activity by human plasmin associated to pathogenic Leptospira interrogans","volume":"51","author":"ML Vieira","year":"2013","journal-title":"Microb Pathog"},{"key":"ref12","first-page":"623","article-title":"Leptospirosis. 3. Maintenance, isolation and demonstration of leptospires","volume":"64","author":"LH Turner","year":"1970","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1002\/prot.340110203","article-title":"Expert system for predicting protein localization sites in gram-negative bacteria","volume":"11","author":"K Nakai","year":"1991","journal-title":"Proteins"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"1402","DOI":"10.1110\/ps.03479604","article-title":"Predicting subcellular localization of proteins for Gram-negative bacteria by support vector machines based on n-peptide compositions","volume":"13","author":"CS Yu","year":"2004","journal-title":"Protein Sci"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"D257","DOI":"10.1093\/nar\/gkj079","article-title":"SMART 5: domains in the context of genomes and networks","volume":"34","author":"I Letunic","year":"2006","journal-title":"Nucleic Acids Res"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"D247","DOI":"10.1093\/nar\/gkj149","article-title":"Pfam: clans, web tools and services","volume":"34","author":"RD Finn","year":"2006","journal-title":"Nucleic Acids Res"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"1652","DOI":"10.1110\/ps.0303703","article-title":"Prediction of lipoprotein signal peptides in Gram-negative bacteria","volume":"12","author":"AS Juncker","year":"2003","journal-title":"Protein Sci"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1038\/msb.2011.75","article-title":"Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega","volume":"7","author":"F Sievers","year":"2011","journal-title":"Mol Syst Biol"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1590\/S0100-879X2004000800001","article-title":"A high-copy T7 Escherichia coli expression vector for the production of recombinant proteins with a minimal N-terminal His-tagged fusion peptide","volume":"37","author":"CR Ramos","year":"2004","journal-title":"Braz J Med Biol Res"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"1750","DOI":"10.1093\/bioinformatics\/btt278","article-title":"CAPITO\u2014a web server-based analysis and plotting tool for circular dichroism data","volume":"29","author":"C Wiedemann","year":"2013","journal-title":"Bioinformatics"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"3679","DOI":"10.1128\/IAI.00474-12","article-title":"OmpL1 is an extracellular matrix- and plasminogen-interacting protein of Leptospira spp","volume":"80","author":"LG Fernandes","year":"2012","journal-title":"Infect Immun"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"564285","DOI":"10.1155\/2014\/564285","article-title":"Induction of boosted immune response in mice by leptospiral surface proteins expressed in fusion with DnaK","volume":"2014","author":"MV Atzingen","year":"2014","journal-title":"Biomed Res Int"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1186\/1471-2180-8-70","article-title":"Lsa21, a novel leptospiral protein binding adhesive matrix molecules and present during human infection","volume":"8","author":"MV Atzingen","year":"2008","journal-title":"BMC Microbiol"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"19380","DOI":"10.1074\/jbc.M109.004531","article-title":"Repeated domains of leptospira immunoglobulin-like proteins interact with elastin and tropoelastin","volume":"284","author":"YP Lin","year":"2009","journal-title":"J Biol Chem"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1002\/cfg.358","article-title":"Identification and analysis of novel tandem repeats in the cell surface proteins of archaeal and bacterial genomes using computational tools","volume":"5","author":"S Adindla","year":"2004","journal-title":"Comp Funct Genomics"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"D205","DOI":"10.1093\/nar\/gkn845","article-title":"CDD: specific functional annotation with the Conserved Domain Database","volume":"37","author":"A Marchler-Bauer","year":"2009","journal-title":"Nucleic Acids Res"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"2947","DOI":"10.1093\/bioinformatics\/btm404","article-title":"Clustal W and Clustal X version 2.0","volume":"23","author":"MA Larkin","year":"2007","journal-title":"Bioinformatics"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1038\/nature08184","article-title":"Proteome-wide cellular protein concentrations of the human pathogen Leptospira interrogans","volume":"460","author":"J Malmstrom","year":"2009","journal-title":"Nature"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1038\/nature01597","article-title":"Unique physiological and pathogenic features of Leptospira interrogans revealed by whole-genome sequencing","volume":"422","author":"SX Ren","year":"2003","journal-title":"Nature"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/j.gene.2012.09.074","article-title":"Sequence of Leptospira santarosai serovar Shermani genome and prediction of virulence-associated genes","volume":"511","author":"LF Chou","year":"2012","journal-title":"Gene"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"14560","DOI":"10.1073\/pnas.0603979103","article-title":"Genome reduction in Leptospira borgpetersenii reflects limited transmission potential","volume":"103","author":"DM Bulach","year":"2006","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"e1853","DOI":"10.1371\/journal.pntd.0001853","article-title":"Whole genome analysis of Leptospira licerasiae provides insight into leptospiral evolution and pathogenicity","volume":"6","author":"JN Ricaldi","year":"2012","journal-title":"PLoS Negl Trop Dis"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"e1607","DOI":"10.1371\/journal.pone.0001607","article-title":"Genome sequence of the saprophyte Leptospira biflexa provides insights into the evolution of Leptospira and the pathogenesis of leptospirosis","volume":"3","author":"M Picardeau","year":"2008","journal-title":"PLoS One"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.micinf.2009.12.004","article-title":"LipL53, a temperature regulated protein from Leptospira interrogans that binds to extracellular matrix molecules","volume":"12","author":"TR Oliveira","year":"2010","journal-title":"Microbes Infect"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1186\/1471-2180-12-50","article-title":"Features of two proteins of Leptospira interrogans with potential role in host-pathogen interactions","volume":"12","author":"RF Domingos","year":"2012","journal-title":"BMC Microbiol"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"6356","DOI":"10.1128\/IAI.00460-06","article-title":"A newly identified leptospiral adhesin mediates attachment to laminin","volume":"74","author":"AS Barbosa","year":"2006","journal-title":"Infect Immun"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"2053","DOI":"10.1128\/IAI.01282-09","article-title":"Leptospiral endostatin-like protein A is a bacterial cell surface receptor for human plasminogen","volume":"78","author":"A Verma","year":"2010","journal-title":"Infect Immun"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.jinf.2009.07.010","article-title":"Lp95, a novel leptospiral protein that binds extracellular matrix components and activates e-selectin on endothelial cells","volume":"59","author":"MV Atzingen","year":"2009","journal-title":"J Infect"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.jinf.2009.10.047","article-title":"Lsa63, a newly identified surface protein of Leptospira interrogans binds laminin and collagen IV","volume":"60","author":"ML Vieira","year":"2010","journal-title":"J Infect"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"e21962","DOI":"10.1371\/journal.pone.0021962","article-title":"Characterization of novel OmpA-like protein of Leptospira interrogans that binds extracellular matrix molecules and plasminogen","volume":"6","author":"R Oliveira","year":"2011","journal-title":"PLoS One"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.micpath.2012.06.001","article-title":"Lsa30, a novel adhesin of Leptospira interrogans binds human plasminogen and the complement regulator C4bp","volume":"53","author":"NM Souza","year":"2012","journal-title":"Microb Pathog"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"4657","DOI":"10.1128\/IAI.05583-11","article-title":"The novel leptospiral surface adhesin Lsa20 binds laminin and human plasminogen and is probably expressed during infection","volume":"79","author":"RS Mendes","year":"2011","journal-title":"Infect Immun"},{"key":"ref43","article-title":"Characterization of Three Novel Adhesins of Leptospira interrogans","author":"GH Siqueira","year":"2013","journal-title":"Am J Trop Med Hyg"},{"key":"ref44","article-title":"Functional and immunological evaluation of two novel proteins of Leptospira spp","author":"LG Fernandes","year":"2014","journal-title":"Microbiology"},{"key":"ref45","first-page":"0.000041","article-title":"The novel Leptospira interrogans protein Lsa32 is expressed during infection and binds laminin and plasminogen","author":"R Domingos","year":"2015","journal-title":"Microbiology"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"4092","DOI":"10.1128\/IAI.00353-09","article-title":"Plasminogen acquisition and activation at the surface of leptospira species lead to fibronectin degradation","volume":"77","author":"ML Vieira","year":"2009","journal-title":"Infect Immun"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1111\/j.1574-6976.2001.tb00590.x","article-title":"Bacterial plasminogen activators and receptors","volume":"25","author":"K Lahteenmaki","year":"2001","journal-title":"FEMS Microbiol Rev"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1006\/bbrc.2002.6657","article-title":"The function of OmpA in Escherichia coli","volume":"292","author":"Y Wang","year":"2002","journal-title":"Biochem Biophys Res Commun"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1574-6968.2007.00778.x","article-title":"A molecular Swiss army knife: OmpA structure, function and expression","volume":"273","author":"SG Smith","year":"2007","journal-title":"FEMS Microbiol Lett"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1128\/JB.184.3.754-759.2002","article-title":"Pal lipoprotein of Escherichia coli plays a major role in outer membrane integrity","volume":"184","author":"E Cascales","year":"2002","journal-title":"J Bacteriol"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1111\/j.1365-2958.2003.03903.x","article-title":"Structure of the OmpA-like domain of RmpM from Neisseria meningitidis","volume":"51","author":"S Grizot","year":"2004","journal-title":"Mol Microbiol"},{"key":"ref52","doi-asserted-by":"crossref","first-page":"2122","DOI":"10.1021\/bi052227i","article-title":"Peptidoglycan recognition by Pal, an outer membrane lipoprotein","volume":"45","author":"LM Parsons","year":"2006","journal-title":"Biochemistry"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/S0378-1097(03)00619-0","article-title":"Molecular cloning and characterization of a novel leptospiral lipoprotein with OmpA domain","volume":"226","author":"N Koizumi","year":"2003","journal-title":"FEMS Microbiol Lett"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"e97","DOI":"10.1371\/journal.ppat.0030097","article-title":"The OmpA-like protein Loa22 is essential for leptospiral virulence","volume":"3","author":"P Ristow","year":"2007","journal-title":"PLoS Pathog"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.femsle.2004.12.021","article-title":"Omp52 is a growth-phase-regulated outer membrane protein of Leptospira santarosai serovar Shermani","volume":"243","author":"WJ Hsieh","year":"2005","journal-title":"FEMS Microbiol Lett"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.jbiotec.2010.04.007","article-title":"Refolding of the recombinant protein OmpA70 from Leptospira interrogans from inclusion bodies using high hydrostatic pressure and partial characterization of its immunological properties","volume":"148","author":"TR Fraga","year":"2010","journal-title":"J Biotechnol"},{"key":"ref57","article-title":"Interaction of spirochetes with the host fibrinolytic system and potential roles in pathogenesis","author":"ML Vieira","year":"2015","journal-title":"Critical Reviews in Microbiology"},{"key":"ref58","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.femsle.2005.02.004","article-title":"Whole-genome analysis of Leptospira interrogans to identify potential vaccine candidates against leptospirosis","volume":"244","author":"M Gamberini","year":"2005","journal-title":"FEMS Microbiol Lett"},{"key":"ref59","doi-asserted-by":"crossref","first-page":"2414","DOI":"10.1128\/IAI.71.5.2414-2421.2003","article-title":"LipL21 is a novel surface-exposed lipoprotein of pathogenic Leptospira species","volume":"71","author":"PA Cullen","year":"2003","journal-title":"Infect Immun"},{"key":"ref60","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1111\/j.1574-6968.2000.tb09034.x","article-title":"Identification of a 36-kDa fibronectin-binding protein expressed by a virulent variant of Leptospira interrogans serovar icterohaemorrhagiae","volume":"185","author":"F Merien","year":"2000","journal-title":"FEMS Microbiol Lett"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"e1188","DOI":"10.1371\/journal.pone.0001188","article-title":"Leptospira interrogans endostatin-like outer membrane proteins bind host fibronectin, laminin and regulators of complement","volume":"2","author":"B Stevenson","year":"2007","journal-title":"PLoS One"},{"key":"ref62","doi-asserted-by":"crossref","first-page":"2659","DOI":"10.1128\/IAI.74.5.2659-2666.2006","article-title":"LfhA, a novel factor H-binding protein of Leptospira interrogans","volume":"74","author":"A Verma","year":"2006","journal-title":"Infect Immun"},{"key":"ref63","doi-asserted-by":"crossref","first-page":"2441","DOI":"10.1128\/IAI.01635-06","article-title":"Physiological osmotic induction of Leptospira interrogans adhesion: LigA and LigB bind extracellular matrix proteins and fibrinogen","volume":"75","author":"HA Choy","year":"2007","journal-title":"Infect Immun"},{"key":"ref64","doi-asserted-by":"crossref","first-page":"2642","DOI":"10.1128\/IAI.01639-07","article-title":"In LipL32, the major leptospiral lipoprotein, the C terminus is the primary immunogenic domain and mediates interaction with collagen IV and plasma fibronectin","volume":"76","author":"P Hauk","year":"2008","journal-title":"Infect Immun"},{"key":"ref65","doi-asserted-by":"crossref","first-page":"2063","DOI":"10.1128\/IAI.01643-07","article-title":"LipL32 is an extracellular matrix-interacting protein of Leptospira spp. and Pseudoalteromonas tunicata","volume":"76","author":"DE Hoke","year":"2008","journal-title":"Infect Immun"},{"key":"ref66","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1016\/j.febslet.2009.03.050","article-title":"Leptospiral TlyC is an extracellular matrix-binding protein and does not present hemolysin activity","volume":"583","author":"E Carvalho","year":"2009","journal-title":"FEBS Lett"},{"key":"ref67","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1006\/mpat.2001.0469","article-title":"Teichoic acid enhances adhesion of Staphylococcus epidermidis to immobilized fibronectin","volume":"31","author":"M Hussain","year":"2001","journal-title":"Microb Pathog"},{"key":"ref68","doi-asserted-by":"crossref","first-page":"29732","DOI":"10.1016\/S0021-9258(18)43942-7","article-title":"Interaction of enteropathogenic Yersinia enterocolitica with complex basement membranes and the extracellular matrix proteins collagen type IV, laminin-1 and -2, and nidogen\/entactin","volume":"269","author":"A Flugel","year":"1994","journal-title":"J Biol Chem"},{"key":"ref69","doi-asserted-by":"crossref","first-page":"4902","DOI":"10.1128\/IAI.70.9.4902-4907.2002","article-title":"The Haemophilus influenzae Hap autotransporter binds to fibronectin, laminin, and collagen IV","volume":"70","author":"DL Fink","year":"2002","journal-title":"Infect Immun"},{"key":"ref70","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1160\/TH07-02-0117","article-title":"Fibrinolysis and host response in bacterial infections","volume":"98","author":"S Bergmann","year":"2007","journal-title":"Thromb Haemost"},{"key":"ref71","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1016\/j.bbapap.2006.06.003","article-title":"Characterization of a fibrinolytic enzyme (ussurenase) from Agkistrodon blomhoffii ussurensis snake venom: insights into the effects of Ca2+ on function and structure","volume":"1764","author":"MZ Sun","year":"2006","journal-title":"Biochim Biophys Acta"},{"key":"ref72","doi-asserted-by":"crossref","first-page":"10224","DOI":"10.1073\/pnas.95.17.10224","article-title":"A novel mechanism for the acquisition of virulence by a human influenza A virus","volume":"95","author":"H Goto","year":"1998","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref73","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.actatropica.2008.04.013","article-title":"Characteristics of plasminogen binding to Trypanosoma cruzi epimastigotes","volume":"107","author":"M Rojas","year":"2008","journal-title":"Acta Trop"},{"key":"ref74","doi-asserted-by":"crossref","first-page":"2478","DOI":"10.1128\/IAI.63.7.2478-2484.1995","article-title":"Borrelia burgdorferi binds plasminogen, resulting in enhanced penetration of endothelial monolayers","volume":"63","author":"JL Coleman","year":"1995","journal-title":"Infect Immun"},{"key":"ref75","doi-asserted-by":"crossref","first-page":"1884","DOI":"10.1128\/IAI.68.4.1884-1892.2000","article-title":"Identification of a Treponema denticola OppA homologue that binds host proteins present in the subgingival environment","volume":"68","author":"JC Fenno","year":"2000","journal-title":"Infect Immun"},{"key":"ref76","doi-asserted-by":"crossref","first-page":"e2396","DOI":"10.1371\/journal.pntd.0002396","article-title":"Adhesins of Leptospira interrogans mediate the interaction to fibrinogen and inhibit fibrin clot formation in vitro","volume":"7","author":"R Oliveira","year":"2013","journal-title":"PLoS Negl Trop Dis"},{"key":"ref77","doi-asserted-by":"crossref","first-page":"e815","DOI":"10.1371\/journal.pntd.0000815","article-title":"The OmpL37 surface-exposed protein is expressed by pathogenic Leptospira during infection and binds skin and vascular elastin","volume":"4","author":"M Pinne","year":"2010","journal-title":"PLoS Negl Trop Dis"},{"key":"ref78","doi-asserted-by":"crossref","first-page":"1528","DOI":"10.1128\/JCM.02344-06","article-title":"Leptospira immunoglobulin-like proteins as a serodiagnostic marker for acute leptospirosis","volume":"45","author":"J Croda","year":"2007","journal-title":"J Clin Microbiol"},{"key":"ref79","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1099\/jmm.0.011916-0","article-title":"A newly identified protein of Leptospira interrogans mediates binding to laminin","volume":"58","author":"MT Longhi","year":"2009","journal-title":"J Med Microbiol"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0122762","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,4]],"date-time":"2022-05-04T14:48:21Z","timestamp":1651675701000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0122762"}},"subtitle":[],"editor":[{"given":"Odir A","family":"Dellagostin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2015,4,7]]},"references-count":79,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2015,4,7]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0122762","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,4,7]]}}}