{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T23:22:39Z","timestamp":1767828159327,"version":"3.49.0"},"reference-count":43,"publisher":"Public Library of Science (PLoS)","issue":"4","license":[{"start":{"date-parts":[[2015,4,7]],"date-time":"2015-04-07T00:00:00Z","timestamp":1428364800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0123014","type":"journal-article","created":{"date-parts":[[2015,4,7]],"date-time":"2015-04-07T18:24:15Z","timestamp":1428431055000},"page":"e0123014","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":77,"title":["Burden of Invasive Group B Streptococcus Disease and Early Neurological Sequelae in South African Infants"],"prefix":"10.1371","volume":"10","author":[{"given":"Ziyaad","family":"Dangor","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjay G.","family":"Lala","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clare L.","family":"Cutland","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthonet","family":"Koen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa","family":"Jose","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Firdose","family":"Nakwa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tanusha","family":"Ramdin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joy","family":"Fredericks","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeannette","family":"Wadula","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shabir A.","family":"Madhi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2015,4,7]]},"reference":[{"issue":"8","key":"ref1","doi-asserted-by":"crossref","first-page":"e1001080","DOI":"10.1371\/journal.pmed.1001080","article-title":"Neonatal mortality levels for 193 countries in 2009 with trends since 1990: a systematic analysis of progress, projections, and priorities","volume":"8","author":"MZ Oestergaard","year":"2011","journal-title":"PLOS Med"},{"issue":"8","key":"ref2","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1016\/S1473-3099(14)70804-7","article-title":"Estimates of possible severe bacterial infection in neonates in sub-Saharan Africa, south Asia, and Latin America for 2012: a systematic review and meta-analysis","volume":"14","author":"AC Seale","year":"2014","journal-title":"Lancet Infect Dis"},{"issue":"11","key":"ref3","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1097\/INF.0b013e318223bad2","article-title":"The burden of invasive early-onset neonatal sepsis in the United States, 2005\u20132008","volume":"30","author":"EJ Weston","year":"2011","journal-title":"Pediatr Infect Dis J"},{"issue":"21","key":"ref4","doi-asserted-by":"crossref","first-page":"2016","DOI":"10.1056\/NEJMoa1005384","article-title":"Bacterial meningitis in the United States, 1998\u20132007","volume":"364","author":"MC Thigpen","year":"2011","journal-title":"N Engl J Med"},{"issue":"Suppl 4","key":"ref5","doi-asserted-by":"crossref","first-page":"D20","DOI":"10.1016\/j.vaccine.2012.11.056","article-title":"Intrapartum antibiotic prophylaxis for the prevention of perinatal group B streptococcal disease: experience in the United States and implications for a potential group B streptococcal vaccine","volume":"31","author":"SJ Schrag","year":"2013","journal-title":"Vaccine"},{"issue":"11","key":"ref6","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1097\/INF.0b013e3181e74c83","article-title":"Early outcomes of group B streptococcal meningitis in the 21st century","volume":"29","author":"F Levent","year":"2010","journal-title":"Pediatr Infect Dis J"},{"issue":"5","key":"ref7","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1016\/S0022-3476(85)80342-5","article-title":"Long-term sequelae of group B streptococcal meningitis in infants","volume":"106","author":"MS Edwards","year":"1985","journal-title":"J Pediatr"},{"issue":"2","key":"ref8","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1542\/peds.77.2.217","article-title":"Long-term outcome of group B streptococcal meningitis","volume":"77","author":"ER Wald","year":"1986","journal-title":"Pediatrics"},{"issue":"7312","key":"ref9","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1136\/bmj.323.7312.533","article-title":"Meningitis in infancy in England and Wales: follow up at age 5 years","volume":"323","author":"H Bedford","year":"2001","journal-title":"BMJ"},{"issue":"1","key":"ref10","doi-asserted-by":"crossref","first-page":"e8","DOI":"10.1542\/peds.2011-3453","article-title":"Long-term Outcomes of Group B Streptococcal Meningitis","volume":"130","author":"R Libster","year":"2012","journal-title":"Pediatrics"},{"issue":"1","key":"ref11","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1179\/000349803125002814","article-title":"High burden of invasive Streptococcus agalactiae disease in South African infants","volume":"23","author":"SA Madhi","year":"2003","journal-title":"Ann Trop Paediatr"},{"issue":"1","key":"ref12","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1093\/cid\/cis395","article-title":"Variation in reported neonatal group B streptococcal disease incidence in developing countries","volume":"55","author":"AF Dagnew","year":"2012","journal-title":"Clin Infect Dis"},{"issue":"9815","key":"ref13","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/S0140-6736(11)61651-6","article-title":"Group B streptococcal disease in infants aged younger than 3 months: systematic review and meta-analysis","volume":"379","author":"KM Edmond","year":"2012","journal-title":"Lancet"},{"key":"ref14","first-page":"12","article-title":"The National Antenatal Sentinel HIV and Syphilis Prevalence Survey","year":"2011"},{"issue":"3","key":"ref15","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1542\/peds.2010-0183","article-title":"High incidence of invasive group B streptococcal infections in HIV-exposed uninfected infants","volume":"126","author":"C Epalza","year":"2010","journal-title":"Pediatrics"},{"key":"ref16","year":"2010"},{"key":"ref17","first-page":"8","article-title":"The South African Antiretroviral Treatment Guidelines, PMTCT Guidelines","year":"2013"},{"issue":"6","key":"ref18","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1542\/peds.89.6.1221","article-title":"Accuracy of the Denver-II in developmental screening","volume":"89","author":"FP Glascoe","year":"1992","journal-title":"Pediatrics"},{"issue":"1","key":"ref19","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1542\/peds.89.1.91","article-title":"The Denver II: a major revision and restandardization of the Denver Developmental Screening Test","volume":"89","author":"WK Frankenburg","year":"1992","journal-title":"Pediatrics"},{"issue":"6","key":"ref20","doi-asserted-by":"crossref","first-page":"e98778","DOI":"10.1371\/journal.pone.0098778","article-title":"Serotype-specific acquisition and loss of group B streptococcus recto-vaginal colonization in late pregnancy","volume":"9","author":"G Kwatra","year":"2014","journal-title":"PLOS One"},{"issue":"4","key":"ref21","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1128\/JCM.02365-10","article-title":"International external quality assurance for laboratory identification and typing of Streptococcus agalactiae (Group B streptococci)","volume":"49","author":"B Afshar","year":"2011","journal-title":"J Clin Microbiol"},{"issue":"6","key":"ref22","doi-asserted-by":"crossref","first-page":"1985","DOI":"10.1128\/JCM.00159-07","article-title":"Multiplex PCR assay for rapid and accurate capsular typing of group B streptococci","volume":"45","author":"C Poyart","year":"2007","journal-title":"J Clin Microbiol"},{"key":"ref23","year":"2014"},{"issue":"RR-10","key":"ref24","first-page":"1","article-title":"Prevention of perinatal group B streptococcal disease\u2014revised guidelines from CDC, 2010","volume":"59","author":"JR Verani","year":"2010","journal-title":"MMWR Recomm Rep"},{"issue":"3","key":"ref25","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/S0163-4453(05)80003-9","article-title":"Neonatal group B streptococcal infections in Indian (Asian) babies in South Africa","volume":"22","author":"IE Haffejee","year":"1991","journal-title":"J Infect"},{"issue":"1","key":"ref26","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1056\/NEJM200001063420103","article-title":"Group B streptococcal disease in the era of intrapartum antibiotic prophylaxis","volume":"342","author":"SJ Schrag","year":"2000","journal-title":"N Engl J Med"},{"issue":"1","key":"ref27","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1097\/INF.0b013e3181ecbf7e","article-title":"Morbidity among human immunodeficiency virus-exposed but uninfected, human immunodeficiency virus-infected, and human immunodeficiency virus-unexposed infants in Zimbabwe before availability of highly active antiretroviral therapy","volume":"30","author":"A Koyanagi","year":"2011","journal-title":"Pediatr Infect Dis J"},{"issue":"10","key":"ref28","doi-asserted-by":"crossref","first-page":"e47337","DOI":"10.1371\/journal.pone.0047337","article-title":"Mortality and health outcomes of HIV-exposed and unexposed children in a PMTCT cohort in Malawi","volume":"7","author":"M Landes","year":"2012","journal-title":"PLOS One"},{"issue":"1","key":"ref29","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1111\/cei.12251","article-title":"HIV-exposed uninfected children: a growing population with a vulnerable immune system?","volume":"176","author":"L Afran","year":"2014","journal-title":"Clin Exp Immunol"},{"issue":"6","key":"ref30","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1001\/jama.2011.100","article-title":"Maternal HIV infection and antibody responses against vaccine-preventable diseases in uninfected infants","volume":"305","author":"CE Jones","year":"2011","journal-title":"JAMA"},{"key":"ref31","article-title":"Department of Child and Adolescent Health and Development","year":"2005"},{"issue":"3","key":"ref32","doi-asserted-by":"crossref","first-page":"e17861","DOI":"10.1371\/journal.pone.0017861","article-title":"Serotype distribution and invasive potential of group B streptococcus isolates causing disease in infants and colonizing maternal-newborn dyads","volume":"6","author":"M Madzivhandila","year":"2011","journal-title":"PLOS One"},{"issue":"2","key":"ref33","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1086\/313665","article-title":"Invasive disease due to group B Streptococcus in pregnant women and neonates from diverse population groups","volume":"30","author":"DF Zaleznik","year":"2000","journal-title":"Clin Infect Dis"},{"issue":"17","key":"ref34","doi-asserted-by":"crossref","first-page":"2056","DOI":"10.1001\/jama.299.17.2056","article-title":"Epidemiology of invasive group B streptococcal disease in the United States, 1999\u20132005","volume":"299","author":"CR Phares","year":"2008","journal-title":"JAMA"},{"issue":"3","key":"ref35","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0017861","article-title":"Serotype distribution and invasive potential of group B streptococcus isolates causing disease in infants and colonizing maternal-newborn dyads","volume":"6","author":"M Madzivhandila","year":"2011","journal-title":"PLOS One"},{"issue":"5","key":"ref36","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1093\/cid\/cit337","article-title":"Emerging trends in the epidemiology of invasive group B streptococcal disease in England and Wales, 1991\u20132010","volume":"57","author":"TL Lamagni","year":"2013","journal-title":"Clin Infect Dis"},{"issue":"12","key":"ref37","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1097\/INF.0b013e31822a2a1f","article-title":"Genetic differences between invasive and noninvasive neonatal group B streptococcal isolates","volume":"30","author":"K Fluegge","year":"2011","journal-title":"Pediatr Infect Dis J"},{"issue":"Suppl 4","key":"ref38","doi-asserted-by":"crossref","first-page":"D52","DOI":"10.1016\/j.vaccine.2013.02.029","article-title":"Considerations for a phase-III trial to evaluate a group B Streptococcus polysaccharide-protein conjugate vaccine in pregnant women for the prevention of early- and late-onset invasive disease in young-infants","volume":"31","author":"SA Madhi","year":"2013","journal-title":"Vaccine"},{"issue":"1\u20132","key":"ref39","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1155\/NP.2003.93","article-title":"Development and plasticity of the corticospinal system in man","volume":"10","author":"JA Eyre","year":"2003","journal-title":"Neural Plast"},{"issue":"Suppl 4","key":"ref40","doi-asserted-by":"crossref","first-page":"D27","DOI":"10.1016\/j.vaccine.2013.02.031","article-title":"Assessments of vaccines for prenatal immunization","volume":"31","author":"MC Steinhoff","year":"2013","journal-title":"Vaccine"},{"issue":"9953","key":"ref41","doi-asserted-by":"crossref","first-page":"1521","DOI":"10.1016\/S0140-6736(14)60686-3","article-title":"Effectiveness of maternal pertussis vaccination in England: an observational study","volume":"384","author":"G Amirthalingam","year":"2014","journal-title":"Lancet"},{"issue":"10","key":"ref42","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1056\/NEJMoa1401480","article-title":"Influenza vaccination of pregnant women and protection of their infants","volume":"371","author":"SA Madhi","year":"2014","journal-title":"N Engl J Med"},{"key":"ref43","unstructured":"Heyderman R, French N, Madhi S, Cutland C, Ngwira B, Mboizi R, et al. Safety and Immunogenicity of Investigational Group B Streptococcus Trivalent Polysaccharide-Conjugate Vaccine in HIV-infected and Uninfected Pregnant African Women and Newborns. European Society for Paediatric Infectious Diseases; Dublin, Ireland; 2014."}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0123014","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,4]],"date-time":"2022-05-04T14:45:01Z","timestamp":1651675501000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0123014"}},"subtitle":[],"editor":[{"given":"Jose","family":"Melo-Cristino","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2015,4,7]]},"references-count":43,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2015,4,7]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0123014","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,4,7]]}}}