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Preventing Hospital-Acquired Venous Thromboembolism: A Guide for Effective Quality Improvement. Prepared by the Society of Hospital Medicine. AHRQ Publication No. 08\u20130075. Rockville, MD. AHRQ. 2010 August."},{"issue":"2 Suppl","key":"ref12","doi-asserted-by":"crossref","first-page":"7S","DOI":"10.1378\/chest.1412S3","article-title":"Executive summary: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines","volume":"141","author":"GH Guyatt","year":"2012","journal-title":"Chest"},{"issue":"9","key":"ref13","doi-asserted-by":"crossref","first-page":"625","DOI":"10.7326\/0003-4819-155-9-201111010-00011","article-title":"Venous thromboembolism prophylaxis in hospitalized patients: a clinical practice guideline from the American College of Physicians","volume":"155","author":"A Qaseem","year":"2011","journal-title":"Ann Intern Med"},{"issue":"5","key":"ref14","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1097\/MLR.0b013e31819432cd","article-title":"Quality of care provided to individual patients in US hospitals: results from an analysis of national Hospital Quality Alliance data","volume":"47","author":"C Vogeli","year":"2009","journal-title":"Medical care"},{"key":"ref15","article-title":"Chenoweth J. Hospital Performance Differences by Ownership. Research Brief","author":"D Foster","year":"2013"},{"key":"ref16","unstructured":"Houchens R, Chu B, Steiner C. Hierarchical modeling using HCUP data. HCUP methods series report # 2007\u201301 Online. January 10, 2007. U.S. Agency for Healthcare Research and Quality. Available: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.hcup-us.ahrq.gov\/reports\/methods.jsp\" xlink:type=\"simple\">http:\/\/www.hcup-us.ahrq.gov\/reports\/methods.jsp<\/ext-link>. Last accessed: June 14, 2013. 2007."},{"issue":"4","key":"ref17","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/j.jamcollsurg.2009.01.002","article-title":"Venous Thromboembolism as a Marker of Quality of Care in Trauma","volume":"208","author":"K Huseynova","year":"2009","journal-title":"Journal of the American College of Surgeons"},{"key":"ref18","article-title":"Overview of the Nationwide Inpatient Sample (NIS)","year":"2013"},{"key":"ref19","article-title":"Healthcare Cost and Utilization Project (HCUP)","year":"2011"},{"issue":"1","key":"ref20","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1097\/00005650-199801000-00004","article-title":"Comorbidity measures for use with administrative data","volume":"36","author":"A Elixhauser","year":"1998","journal-title":"Med Care"},{"key":"ref21","year":"2012"},{"key":"ref22","article-title":"Procedure Classes 2012","year":"2012"},{"key":"ref23","year":"2012"},{"key":"ref24","doi-asserted-by":"crossref","DOI":"10.1007\/978-3-642-04898-2_387","article-title":"Multilevel Analysis: An Introduction to Basic and Advanced Multilevel Modeling","author":"TAB Snijders","year":"2011"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1186\/1471-2288-9-49","article-title":"Fitting multilevel models in complex survey data with design weights: Recommendations","volume":"9","author":"AC Carle","year":"2009","journal-title":"BMC Med Res Methodol"},{"issue":"5","key":"ref26","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1097\/MCP.0b013e3281eb8ef0","article-title":"The effects of race\/ethnicity and sex on the risk of venous thromboembolism","volume":"13","author":"CR Keenan","year":"2007","journal-title":"Current opinion in pulmonary medicine"},{"key":"ref27","doi-asserted-by":"crossref","unstructured":"Yusuf HR, Reyes N, Zhang QC, Okoroh EM, Siddiqi AE, Tsai J. Hospitalizations of Adults &gt; = 60 Years of Age With Venous Thromboembolism. 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