{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,11,5]],"date-time":"2022-11-05T15:08:44Z","timestamp":1667660924079},"reference-count":24,"publisher":"Public Library of Science (PLoS)","issue":"5","license":[{"start":{"date-parts":[[2015,5,13]],"date-time":"2015-05-13T00:00:00Z","timestamp":1431475200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0124847","type":"journal-article","created":{"date-parts":[[2015,5,13]],"date-time":"2015-05-13T18:12:42Z","timestamp":1431540762000},"page":"e0124847","update-policy":"http:\/\/dx.doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":3,"title":["Multilocus Heterozygosity and Coronary Heart Disease: Nested Case-Control Studies in Men and Women"],"prefix":"10.1371","volume":"10","author":[{"given":"Kenneth J.","family":"Mukamal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Majken K.","family":"Jensen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tune H.","family":"Pers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer K.","family":"Pai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Kraft","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric B.","family":"Rimm","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2015,5,13]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1038\/nature06862","article-title":"Mapping and sequencing of structural variation from eight human genomes","volume":"453","author":"JM Kidd","year":"2008","journal-title":"Nature"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1111\/j.1399-0004.2005.00503.x","article-title":"The hemoglobinopathies and malaria","volume":"68","author":"J Richer","year":"2005","journal-title":"Clin Genet"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"2473","DOI":"10.1111\/j.1558-5646.2008.00478.x","article-title":"Genetic diversity revealed in human faces","volume":"62","author":"HC Lie","year":"2008","journal-title":"Evolution"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1068\/p6626","article-title":"Why are mixed-race people perceived as more attractive?","volume":"39","author":"MB Lewis","year":"2010","journal-title":"Perception"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1007\/s100380050161","article-title":"Polymorphic forms of the protein L-isoaspartate (D-aspartate) O-methyltransferase involved in the repair of age-damaged proteins","volume":"44","author":"CG DeVry","year":"1999","journal-title":"J Hum Genet"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1016\/j.exger.2004.03.034","article-title":"Gender specific association of genetic variation in peroxisome proliferator-activated receptor (PPAR)gamma-2 with longevity","volume":"39","author":"M Barbieri","year":"2004","journal-title":"Exp Gerontol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1093\/hmg\/ddl473","article-title":"Effects of genome-wide heterozygosity on a range of biomedically relevant human quantitative traits","volume":"16","author":"H Campbell","year":"2007","journal-title":"Hum Mol Genet"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1111\/j.1469-1809.2009.00514.x","article-title":"Association between SNP heterozygosity and quantitative traits in the Framingham Heart Study","volume":"73","author":"DR Govindaraju","year":"2009","journal-title":"Ann Hum Genet"},{"key":"ref9","first-page":"1","article-title":"Deaths: final data for 2006","volume":"57","author":"M Heron","year":"2009","journal-title":"Natl Vital Stat Rep"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/0140-6736(91)90542-W","article-title":"Prospective study of alcohol consumption and risk of coronary disease in men","volume":"338","author":"EB Rimm","year":"1991","journal-title":"Lancet"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1056\/NEJM198510243131703","article-title":"A prospective study of postmenopausal estrogen therapy and coronary heart disease","volume":"313","author":"MJ Stampfer","year":"1985","journal-title":"N Engl J Med"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1093\/biomet\/65.1.153","article-title":"Retrospective studies and failure time models","volume":"65","author":"RL Prentice","year":"1978","journal-title":"Biometrika"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.1093\/clinchem\/48.10.1781","article-title":"Stability of novel plasma markers associated with cardiovascular disease: processing within 36 hours of specimen collection","volume":"48","author":"JK Pai","year":"2002","journal-title":"Clin Chem"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1038\/oby.2003.145","article-title":"Leisure-time physical activity and reduced plasma levels of obesity-related inflammatory markers","volume":"11","author":"T Pischon","year":"2003","journal-title":"Obes Res"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1097\/00001648-199011000-00009","article-title":"Validity of self-reported waist and hip circumferences in men and women","volume":"1","author":"EB Rimm","year":"1990","journal-title":"Epidemiology"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1002\/gepi.20424","article-title":"Genome-wide association scans for secondary traits using case-control samples","volume":"33","author":"GM Monsees","year":"2009","journal-title":"Genet Epidemiol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1086\/519795","article-title":"PLINK: a tool set for whole-genome association and population-based linkage analyses","volume":"81","author":"S Purcell","year":"2007","journal-title":"Am J Hum Genet"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1007\/s10519-008-9191-6","article-title":"Genetic heterozygosity and sociality in a primate species","volume":"38","author":"MJ Charpentier","year":"2008","journal-title":"Behav Genet"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.evolhumbehav.2004.09.002","article-title":"MHC-heterozygosity and human facial attractiveness","volume":"26","author":"SC Roberts","year":"2005","journal-title":"Evolution and Human Behavior"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"e1002656","DOI":"10.1371\/journal.pgen.1002656","article-title":"Runs of homozygosity implicate autozygosity as a schizophrenia risk factor","volume":"8","author":"MC Keller","year":"2012","journal-title":"PLoS genetics"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"1856","DOI":"10.1093\/hmg\/ddq057","article-title":"Genetic variants in ABO blood group region, plasma soluble E-selectin levels and risk of type 2 diabetes","volume":"19","author":"L Qi","year":"2010","journal-title":"Hum Mol Genet"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"2250","DOI":"10.1182\/blood-2007-03-077602","article-title":"The ABO blood group system and Plasmodium falciparum malaria","volume":"110","author":"CM Cserti","year":"2007","journal-title":"Blood"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1534\/genetics.111.130922","article-title":"Quantification of inbreeding due to distant ancestors and its detection using dense single nucleotide polymorphism data","volume":"189","author":"MC Keller","year":"2011","journal-title":"Genetics"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1016\/0140-6736(91)91828-I","article-title":"Consanguinity and adult morbidity in Pakistan","volume":"338","author":"SA Shami","year":"1991","journal-title":"Lancet"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0124847","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,2]],"date-time":"2020-09-02T04:35:57Z","timestamp":1599021357000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0124847"}},"subtitle":[],"editor":[{"given":"Gualtiero I.","family":"Colombo","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2015,5,13]]},"references-count":24,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2015,5,13]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0124847","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,5,13]]}}}