{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T08:02:14Z","timestamp":1777276934123,"version":"3.51.4"},"reference-count":35,"publisher":"Public Library of Science (PLoS)","issue":"5","license":[{"start":{"date-parts":[[2015,5,12]],"date-time":"2015-05-12T00:00:00Z","timestamp":1431388800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0126554","type":"journal-article","created":{"date-parts":[[2015,5,12]],"date-time":"2015-05-12T17:59:31Z","timestamp":1431453571000},"page":"e0126554","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":23,"title":["Symptom Clusters in People Living with HIV Attending Five Palliative Care Facilities in Two Sub-Saharan African Countries: A Hierarchical Cluster Analysis"],"prefix":"10.1371","volume":"10","author":[{"given":"Katrien","family":"Moens","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard J.","family":"Siegert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steve","family":"Taylor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eve","family":"Namisango","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Harding","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"ENCOMPASS","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"EURO IMPACT","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2015,5,12]]},"reference":[{"key":"ref1","first-page":"1195","article-title":"Oxford Textbook of Palliative Medicine","author":"R Woodruff","year":"2010"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1016\/j.jpainsymman.2013.11.009","article-title":"Are there differences in the prevalence of palliative care-related problems in people living with advanced cancer and eight non-cancer conditions? A systematic review","volume":"48","author":"K Moens","year":"2014","journal-title":"J Pain Symptom Manage"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1016\/j.jpainsymman.2012.09.011","article-title":"Functional impairments as symptoms in the symptom cluster analysis of patients newly diagnosed with advanced cancer","volume":"46","author":"S Fodeh","year":"2013","journal-title":"J Pain Symptom Manage"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1093\/jncimonographs\/lgh023","article-title":"Symptom clusters: the new frontier in symptom management research","volume":"32","author":"C Miaskoswki","year":"2004","journal-title":"JNCI"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1093\/jncimonographs\/lgh008","article-title":"Occurrence of symptom clusters","volume":"32","author":"M Dodd","year":"2004","journal-title":"JNCI Monographs"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1177\/0269216310367842","article-title":"Review: Symptom clusters: myth or reality?","volume":"24","author":"A Aktas","year":"2010","journal-title":"Palliat Med"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1046\/j.1365-2648.1999.01204.x","article-title":"Validation of the Sign and Symptom Check-List for Persons with HIV Disease (SSC-HIV)","volume":"30","author":"W Holzemer","year":"1999","journal-title":"J Adv Nurs"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1089\/jpm.2010.0507","article-title":"Cancer symptom clusters: clinical and research methodology","volume":"14","author":"J Kirkova","year":"2011","journal-title":"Journal Palliat Medicine"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1177\/082585979300900203","article-title":"Metoclopramide in anorexia caused by cancer-associated dyspepsia syndrome (CADS)","volume":"9","author":"K Nelson","year":"1993","journal-title":"J Palliat Care"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S1098-3597(05)80003-1","article-title":"Cancer pain, fatigue, distress, and insomnia in cancer patients","volume":"6","author":"D Theobald","year":"2004","journal-title":"Clin Cornerstone"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1007\/s00520-007-0259-2","article-title":"Cancer symptom clusters\u2014A dynamic construct","volume":"15","author":"J Kirkova","year":"2007","journal-title":"Support Care Cancer"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"19096","DOI":"10.7448\/IAS.17.1.19096","article-title":"Comment on &quot;Pain in people living with HIV\/AIDS: a systematic review (Parker et al. 2014)","volume":"17","author":"R Harding","year":"2014","journal-title":"J Int AIDS Soc"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"1708","DOI":"10.1007\/s10461-011-0023-y","article-title":"Behavioural surveillance study: sexual risk taking behaviour in UK HIV outpatient attendees","volume":"16","author":"R Harding","year":"2012","journal-title":"AIDS Behav"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1080\/09540120701867032","article-title":"Adherence to antiretroviral treatment in patients with HIV in the UK: a study of complexity","volume":"20","author":"L Sherr","year":"2008","journal-title":"Aids Care-Psychological and Socio-Medical Aspects of Aids\/hiv"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1111\/j.1468-1293.2010.00851.x","article-title":"Doctor-patient concordance during HIV treatment switching decision-making","volume":"12","author":"C Clucas","year":"2011","journal-title":"HIV Med"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1097\/QAI.0b013e3181ce6afe","article-title":"Physical and Psychological Symptoms and Risk of Virologic Rebound Among Patients With Virologic Suppression on Antiretroviral Therapy","volume":"54","author":"FC Lampe","year":"2010","journal-title":"J Acquir Immune Defic Syndr"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1080\/09540121.2012.668175","article-title":"What factors are associated with patient self-reported health status among HIV outpatients? A multicentre UK study of biomedical and psychosocial factors","volume":"24","author":"R Harding","year":"2012","journal-title":"AIDS Care"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.1097\/QAD.0b013e32830c4804","article-title":"Suicidal ideation in UK HIV clinic attenders","volume":"22","author":"L Sherr","year":"2008","journal-title":"AIDS"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jpainsymman.2011.08.008","article-title":"Prevalence, Burden, and Correlates of Physical and Psychological Symptoms Among HIV Palliative Care Patients in Sub-Saharan Africa: An International Multicentre Study","volume":"44","author":"R Harding","year":"2012","journal-title":"J Pain Symptom Manage"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1002\/1097-0142(20000901)89:5<1162::AID-CNCR26>3.0.CO;2-Y","article-title":"The Memorial Symptom Assessment Scale Short Form (MSAS-SF)","volume":"89","author":"V Chang","year":"2000","journal-title":"Cancer"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1089\/jpm.2009.0259","article-title":"Symptom burden in HIV infected adults at time of HIV diagnosis in rural Uganda","volume":"13","author":"K Wakeham","year":"2010","journal-title":"J Palliat Med"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/S0885-3924(00)00245-1","article-title":"The use of highly active antiretroviral therapy (HAART) in patients with advanced HIV infection: impact on medical, palliative care, and quality of life outcomes","volume":"21","author":"J Brechtl","year":"2001","journal-title":"J Pain Symptom Manage"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1258\/095646206777323409","article-title":"Is antiretroviral therapy associated with symptom prevalence and burden?","volume":"17","author":"R Harding","year":"2006","journal-title":"Int J STD AIDS"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/j.jpainsymman.2005.04.011","article-title":"Patient reports of symptoms and their treatment at three palliative care projects servicing individuals with HIV\/ AIDS","volume":"30","author":"D Karus","year":"2005","journal-title":"J Pain Symptom Manage"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1089\/109662103322144844","article-title":"Palliative care for AIDS at a large urban teaching hospital: program description and preliminary outcomes","volume":"6","author":"P Selwyn","year":"2003","journal-title":"J Palliat Med"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1136\/sti.2009.038505","article-title":"Symptoms are highly prevalent among HIV outpatients and associated with poor adherence and unprotected sexual intercourse","volume":"86","author":"R Harding","year":"2010","journal-title":"Sex Transm Infect"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1097\/00000421-198212000-00014","article-title":"Toxicity And Response Criteria Of The Eastern Cooperative Oncology Group","volume":"5","author":"M Oken","year":"1982","journal-title":"Am J Clin Oncol"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1080\/09540121.2013.844765","article-title":"The presence of CD4 counts for the management of HIV patients in East Africa: A multicentre study","volume":"26","author":"R Harding","year":"2014","journal-title":"AIDS Care"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1016\/j.jpainsymman.2009.05.025","article-title":"Assessing the symptoms of cancer using patient-reported outcomes (ASC-PRO): searching for standards","volume":"39","author":"C Cleeland","year":"2000","journal-title":"J Pain Symptom Manage"},{"key":"ref30","article-title":"Business Research Methods and Statistics using SPSS","author":"R Burns","year":"2009"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1016\/j.ijnurstu.2014.01.015","article-title":"Experience of persistent psychological symptoms and perceived stigma among people with HIV on antiretroviral therapy (ART): a systematic review","volume":"51","author":"K Lowther","year":"2014","journal-title":"Int J Nurs Stud"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1176\/appi.psy.41.4.294","article-title":"Anxiety syndromes and symptoms among men with AIDS: a longitudinal controlled study","volume":"41","author":"MC Sewell","year":"2000","journal-title":"Psychosomatics"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1097\/QAI.0B013E31822D490A","article-title":"Depression and HIV\/AIDS treatment non-adherence: a review and meta-analysis","volume":"58","author":"J Gonzalez","year":"2011","journal-title":"J Acquir Immune Defic Syndr"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1089\/jpm.2013.0291","article-title":"Is symptom burden associated with treatment status and disease stage among adult HIV outpatients in East Africa?","volume":"17","author":"E Namisango","year":"2014","journal-title":"J Palliat Med"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"119","DOI":"10.7196\/samj.7461","article-title":"Maintaining wellbeing for South Africans receiving ART: the burden of pain and symptoms is greater with longer ART exposure","volume":"104","author":"L Farrant","year":"2014","journal-title":"S Afr Med J"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0126554","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,25]],"date-time":"2019-08-25T00:39:00Z","timestamp":1566693540000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0126554"}},"subtitle":[],"editor":[{"given":"Waldo","family":"Belloso","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2015,5,12]]},"references-count":35,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2015,5,12]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0126554","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,5,12]]}}}