{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T00:16:27Z","timestamp":1776903387667,"version":"3.51.2"},"reference-count":34,"publisher":"Public Library of Science (PLoS)","issue":"6","license":[{"start":{"date-parts":[[2015,6,15]],"date-time":"2015-06-15T00:00:00Z","timestamp":1434326400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0129144","type":"journal-article","created":{"date-parts":[[2015,6,15]],"date-time":"2015-06-15T18:10:34Z","timestamp":1434391834000},"page":"e0129144","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":25,"title":["Genetic Variation in NFKB1 and NFKBIA and Susceptibility to Coronary Artery Disease in a Chinese Uygur Population"],"prefix":"10.1371","volume":"10","author":[{"given":"Hong-Mei","family":"Lai","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao-Mei","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi-Ning","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi-Tong","family":"Ma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rui","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuo","family":"Pan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui","family":"Zhai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fen","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bang-Dang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qian","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2015,6,15]]},"reference":[{"issue":"5830","key":"ref1","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1126\/science.1142842","article-title":"A common variant on chromosome 9p21 affects the risk of myocardial infarction","volume":"316","author":"A Helgadottir","year":"2007","journal-title":"Science"},{"issue":"5830","key":"ref2","doi-asserted-by":"crossref","first-page":"1488","DOI":"10.1126\/science.1142447","article-title":"A common allele on chromosome 9 associated with coronary heart disease","volume":"316","author":"R McPherson","year":"2007","journal-title":"Science"},{"issue":"5","key":"ref3","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1056\/NEJMoa072366","article-title":"Genomewide association analysis of coronary artery disease","volume":"357","author":"NJ Samani","year":"2007","journal-title":"The New England journal of medicine"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1146\/annurev.genom.5.061903.175930","article-title":"Genetics of atherosclerosis","volume":"5","author":"AJ Lusis","year":"2004","journal-title":"Annual review of genomics and human genetics"},{"issue":"9","key":"ref5","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1161\/hc0902.104353","article-title":"Inflammation and atherosclerosis","volume":"105","author":"P Libby","year":"2002","journal-title":"Circulation"},{"issue":"6801","key":"ref6","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1038\/35025203","article-title":"Atherosclerosis","volume":"407","author":"AJ Lusis","year":"2000","journal-title":"Nature"},{"issue":"5","key":"ref7","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1161\/01.ATV.0000160340.72641.87","article-title":"Nuclear factor kappaB signaling in atherogenesis","volume":"25","author":"MP de Winther","year":"2005","journal-title":"Arteriosclerosis, thrombosis, and vascular biology"},{"issue":"8","key":"ref8","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.1016\/j.biocel.2007.05.004","article-title":"Nuclear factor-kappaB1: regulation and function","volume":"40","author":"SG Pereira","year":"2008","journal-title":"The international journal of biochemistry & cell biology"},{"issue":"36","key":"ref9","doi-asserted-by":"crossref","first-page":"26041","DOI":"10.1074\/jbc.M602222200","article-title":"NF-kappaB1 (p50) homodimers differentially regulate pro- and anti-inflammatory cytokines in macrophages","volume":"281","author":"S Cao","year":"2006","journal-title":"The Journal of biological chemistry"},{"issue":"2","key":"ref10","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/j.atherosclerosis.2008.10.037","article-title":"NF-kappaB -94Ins\/Del ATTG polymorphism modifies the association between dietary polyunsaturated fatty acids and HDL-cholesterol in two distinct populations","volume":"204","author":"B Fontaine-Bisson","year":"2009","journal-title":"Atherosclerosis"},{"issue":"4","key":"ref11","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1089\/dna.2011.1389","article-title":"NFKB1\u201394 insertion\/deletion ATTG polymorphism contributes to risk of systemic lupus erythematosus","volume":"31","author":"M Gao","year":"2012","journal-title":"DNA and cell biology"},{"issue":"6","key":"ref12","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1111\/j.1744-313X.2005.00546.x","article-title":"A NFKB1 promoter polymorphism is involved in susceptibility to ulcerative colitis","volume":"32","author":"ME Borm","year":"2005","journal-title":"International journal of immunogenetics"},{"issue":"7","key":"ref13","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1038\/sj.gene.6364418","article-title":"Association of NFKB1 -94ins\/del ATTG promoter polymorphism with susceptibility to and phenotype of Graves&apos; disease","volume":"8","author":"A Kurylowicz","year":"2007","journal-title":"Genes and immunity"},{"issue":"7","key":"ref14","first-page":"1952","article-title":"A novel single-nucleotide polymorphism in the 3&apos;-untranslated region of the human dihydrofolate reductase gene with enhanced expression","volume":"7","author":"Y Goto","year":"2001","journal-title":"Clinical cancer research: an official journal of the American Association for Cancer Research"},{"issue":"6","key":"ref15","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1038\/76211","article-title":"The 3&apos; untranslated region of messenger RNA: A molecular &apos;hotspot&apos; for pathology?","volume":"6","author":"B Conne","year":"2000","journal-title":"Nature medicine"},{"issue":"1","key":"ref16","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/1043-4666(94)90013-2","article-title":"Interleukin 6 gene transcripts are expressed in human atherosclerotic lesions","volume":"6","author":"Y Seino","year":"1994","journal-title":"Cytokine"},{"issue":"15","key":"ref17","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.1161\/01.CIR.101.15.1767","article-title":"Plasma concentration of interleukin-6 and the risk of future myocardial infarction among apparently healthy men","volume":"101","author":"PM Ridker","year":"2000","journal-title":"Circulation"},{"issue":"7","key":"ref18","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1161\/01.ATV.0000079512.66448.1D","article-title":"C-reactive protein, interleukin-6, and fibrinogen as predictors of coronary heart disease: the PRIME Study","volume":"23","author":"G Luc","year":"2003","journal-title":"Arteriosclerosis, thrombosis, and vascular biology"},{"issue":"5","key":"ref19","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1177\/1076029610364522","article-title":"Association of interaction between smoking and CYP 2C19*3 polymorphism with coronary artery disease in a Uighur population","volume":"16","author":"YN Yang","year":"2010","journal-title":"Clinical and applied thrombosis\/hemostasis: official journal of the International Academy of Clinical and Applied Thrombosis\/Hemostasis"},{"issue":"1","key":"ref20","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1515\/CCLM.2011.024","article-title":"Interaction between COX-2 G-765C and smoking in relation to coronary artery disease in a Chinese Uighur population","volume":"49","author":"X Xie","year":"2011","journal-title":"Clinical chemistry and laboratory medicine: CCLM \/ FESCC"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1186\/1476-511X-13-145","article-title":"The association between CYP1A1 genetic polymorphisms and coronary artery disease in the Uygur and Han of China","volume":"13","author":"JG Zou","year":"2014","journal-title":"Lipids in health and disease"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1186\/1476-511X-13-84","article-title":"Association of Egr3 genetic polymorphisms and coronary artery disease in the Uygur and Han of China","volume":"13","author":"X Li","year":"2014","journal-title":"Lipids in health and disease"},{"issue":"12","key":"ref23","doi-asserted-by":"crossref","first-page":"e15181","DOI":"10.1371\/journal.pone.0015181","article-title":"Alcohol consumption and ankle-to-brachial index: results from the Cardiovascular Risk Survey","volume":"5","author":"X Xie","year":"2010","journal-title":"PloS one"},{"issue":"11","key":"ref24","doi-asserted-by":"crossref","first-page":"e13997","DOI":"10.1371\/journal.pone.0013997","article-title":"Polymorphisms in the SAA1\/2 gene are associated with carotid intima media thickness in healthy Han Chinese subjects: the Cardiovascular Risk Survey","volume":"5","author":"X Xie","year":"2010","journal-title":"PloS one"},{"issue":"2","key":"ref25","first-page":"226","article-title":"Guidelines for management of hypertension: why doesn&apos;t evidence lead to unanimity?","volume":"26","author":"A Zuccala","year":"2009","journal-title":"Giornale italiano di nefrologia: organo ufficiale della Societa italiana di nefrologia"},{"issue":"1","key":"ref26","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.atherosclerosis.2011.06.018","article-title":"The NFKB1 ATTG ins\/del polymorphism and risk of coronary heart disease in three independent populations","volume":"219","author":"U Vogel","year":"2011","journal-title":"Atherosclerosis"},{"issue":"3","key":"ref27","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1016\/j.cyto.2012.12.020","article-title":"Role of inflammatory gene polymorphisms in left ventricular dysfunction (LVD) susceptibility in coronary artery disease (CAD) patients","volume":"61","author":"A Mishra","year":"2013","journal-title":"Cytokine"},{"issue":"9","key":"ref28","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/j.numecd.2009.12.012","article-title":"-94 ins\/del ATTG NFKB1 gene variant is associated with lower susceptibility to myocardial infarction","volume":"21","author":"V Boccardi","year":"2011","journal-title":"Nutrition, metabolism, and cardiovascular diseases: NMCD"},{"issue":"9","key":"ref29","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1016\/j.humimm.2006.05.006","article-title":"NFkappaB and its inhibitor IkappaB in relation to type 2 diabetes and its microvascular and atherosclerotic complications","volume":"67","author":"M Romzova","year":"2006","journal-title":"Human immunology"},{"issue":"7","key":"ref30","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.imbio.2014.03.009","article-title":"Polymorphism of the NFKB1 affects the serum inflammatory levels of IL-6 in Hashimoto thyroiditis in a Turkish population","volume":"219","author":"A Koc","year":"2014","journal-title":"Immunobiology"},{"issue":"12","key":"ref31","doi-asserted-by":"crossref","first-page":"2745","DOI":"10.1161\/01.ATV.0000248096.62495.73","article-title":"Increased concentrations of C-reactive protein and IL-6 but not IL-18 are independently associated with incident coronary events in middle-aged men and women: results from the MONICA\/KORA Augsburg case-cohort study, 1984\u20132002","volume":"26","author":"W Koenig","year":"2006","journal-title":"Arteriosclerosis, thrombosis, and vascular biology"},{"issue":"4","key":"ref32","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1536\/ihj.49.391","article-title":"Serum interleukin-6 levels, not genotype, correlate with coronary plaque complexity","volume":"49","author":"LT Kuo","year":"2008","journal-title":"International heart journal"},{"issue":"3","key":"ref33","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1007\/s11739-010-0361-1","article-title":"Inflammatory biomarkers and coronary heart disease: from bench to bedside and back","volume":"5","author":"G Biasillo","year":"2010","journal-title":"Internal and emergency medicine"},{"issue":"10","key":"ref34","doi-asserted-by":"crossref","first-page":"2169","DOI":"10.3899\/jrheum.110340","article-title":"Tocilizumab monotherapy reduces arterial stiffness as effectively as etanercept or adalimumab monotherapy in rheumatoid arthritis: an open-label randomized controlled trial","volume":"38","author":"K Kume","year":"2011","journal-title":"The Journal of rheumatology"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0129144","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,11]],"date-time":"2023-08-11T13:00:07Z","timestamp":1691758807000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0129144"}},"subtitle":[],"editor":[{"given":"Giuseppe Danilo","family":"Norata","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2015,6,15]]},"references-count":34,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2015,6,15]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0129144","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,6,15]]}}}