{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T05:21:56Z","timestamp":1780636916313,"version":"3.54.1"},"reference-count":73,"publisher":"Public Library of Science (PLoS)","issue":"7","license":[{"start":{"date-parts":[[2015,7,2]],"date-time":"2015-07-02T00:00:00Z","timestamp":1435795200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0129914","type":"journal-article","created":{"date-parts":[[2015,7,2]],"date-time":"2015-07-02T18:18:30Z","timestamp":1435861110000},"page":"e0129914","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":9,"title":["Hansenula polymorpha Pmt4p Plays Critical Roles in O-Mannosylation of Surface Membrane Proteins and Participates in Heteromeric Complex Formation"],"prefix":"10.1371","volume":"10","author":[{"given":"Hyunah","family":"Kim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eun Jung","family":"Thak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong-Jik","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael O.","family":"Agaphonov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun Ah","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2015,7,2]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1016\/j.sbi.2003.09.003","article-title":"<italic>O<\/italic>-mannosyl glycans: from yeast to novel associations with human disease","volume":"13","author":"T Willer","year":"2003","journal-title":"Current opinion in structural biology"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/S0304-4165(98)00131-7","article-title":"Protein <italic>O<\/italic>-mannosylation","volume":"1426","author":"S Strahl-Bolsinger","year":"1999","journal-title":"Biochimica et Biophysica Acta\u2014General Subjects"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"12554","DOI":"10.1074\/jbc.M212582200","article-title":"Members of the evolutionarily conserved <italic>PMT<\/italic> family of protein <italic>O<\/italic>-mannosyltransferases form distinct protein complexes among themselves","volume":"278","author":"V Girrbach","year":"2003","journal-title":"The Journal of biological chemistry"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"8164","DOI":"10.1073\/pnas.90.17.8164","article-title":"<italic>PMT1<\/italic>, the gene for a key enzyme of protein <italic>O<\/italic>-glycosylation in <italic>Saccharomyces cerevisiae<\/italic>","volume":"90","author":"S Strahl-Bolsinger","year":"1993","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"5752","DOI":"10.1002\/j.1460-2075.1996.tb00961.x","article-title":"The PMT gene family: protein <italic>O<\/italic>-glycosylation in <italic>Saccharomyces cerevisiae<\/italic> is vital","volume":"15","author":"M Gentzsch","year":"1996","journal-title":"EMBO J"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1111\/j.1365-2958.2010.07164.x","article-title":"Members of protein <italic>O<\/italic>-mannosyltransferase family in <italic>Aspergillus fumigatus<\/italic> differentially affect growth, morphogenesis and viability","volume":"76","author":"I Mouyna","year":"2010","journal-title":"Molecular microbiology"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1128\/EC.00040-09","article-title":"<italic>Aspergillus nidulans<\/italic> protein <italic>O<\/italic>-mannosyltransferases play roles in cell wall integrity and developmental patterning","volume":"8","author":"T Kriangkripipat","year":"2009","journal-title":"Eukaryotic cell"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"e65924","DOI":"10.1371\/journal.pone.0065924","article-title":"<italic>Botrytis cinerea<\/italic> protein <italic>O<\/italic>-mannosyltransferases play critical roles in morphogenesis, growth, and virulence","volume":"8","author":"M Gonzalez","year":"2013","journal-title":"PloS one"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1111\/j.1365-2958.2004.04401.x","article-title":"<italic>PMT<\/italic> family of <italic>Candida albicans<\/italic>: five protein mannosyltransferase isoforms affect growth, morphogenesis and antifungal resistance","volume":"55","author":"SK Prill","year":"2005","journal-title":"Molecular microbiology"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"e6321","DOI":"10.1371\/journal.pone.0006321","article-title":"Characterization of the <italic>PMT<\/italic> gene family in <italic>Cryptococcus neoformans<\/italic>","volume":"4","author":"SD Willger","year":"2009","journal-title":"PloS one"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"e68325","DOI":"10.1371\/journal.pone.0068325","article-title":"Characterization of the <italic>Pichia pastoris<\/italic> protein-<italic>O<\/italic>-mannosyltransferase gene family","volume":"8","author":"JH Nett","year":"2013","journal-title":"PloS one"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"20837","DOI":"10.1074\/jbc.273.33.20837","article-title":"Multiple functions of Pmt1p-mediated protein <italic>O<\/italic>-mannosylation in the fungal pathogen <italic>Candida albicans<\/italic>","volume":"273","author":"C Timpel","year":"1998","journal-title":"The Journal of biological chemistry"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"3063","DOI":"10.1128\/JB.182.11.3063-3071.2000","article-title":"Morphogenesis, adhesive properties, and antifungal resistance depend on the Pmt6 protein mannosyltransferase in the fungal pathogen <italic>Candida albicans<\/italic>","volume":"182","author":"C Timpel","year":"2000","journal-title":"Journal of Bacteriology"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1007\/s00294-003-0368-5","article-title":"cDNA encoding protein <italic>O<\/italic>-mannosyltransferase from the filamentous fungus <italic>Trichoderma reesei<\/italic>; functional equivalence to <italic>Saccharomyces cerevisiae PMT2<\/italic>","volume":"43","author":"A Zakrzewska","year":"2003","journal-title":"Current genetics"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"3397","DOI":"10.1105\/tpc.109.065839","article-title":"The <italic>O<\/italic>-mannosyltransferase <italic>PMT4<\/italic> is essential for normal appressorium formation and penetration in <italic>Ustilago maydis<\/italic>","volume":"21","author":"A Fernandez-Alvarez","year":"2009","journal-title":"The Plant Cell"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"6048","DOI":"10.1073\/pnas.93.12.6048","article-title":"Mutations in the rotated abdomen locus affect muscle development and reveal an intrinsic asymmetry in <italic>Drosophila<\/italic>","volume":"93","author":"E Martin-Blanco","year":"1996","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1093\/glycob\/cwf086","article-title":"Characterization of <italic>POMT2<\/italic>, a novel member of the <italic>PMT<\/italic> protein <italic>O<\/italic>-mannosyltransferase family specifically localized to the acrosome of mammalian spermatids","volume":"12","author":"T Willer","year":"2002","journal-title":"Glycobiology"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1093\/glycob\/cwq069","article-title":"Protein <italic>O<\/italic>-mannosylation is necessary for normal embryonic development in zebrafish","volume":"20","author":"E Avsar-Ban","year":"2010","journal-title":"Glycobiology"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1006\/geno.1999.5819","article-title":"Identification of a human homolog of the Drosophila <italic>rotated abdomen<\/italic> gene (<italic>POMT1<\/italic>) encoding a putative protein <italic>O<\/italic>-mannosyl-transferase, and assignment to human chromosome 9q34.1","volume":"58","author":"LA Jurado","year":"1999","journal-title":"Genomics"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"19288","DOI":"10.1074\/jbc.M001771200","article-title":"Structure-function analysis of the dolichyl phosphate-mannose: protein <italic>O<\/italic>-mannosyltransferase ScPmt1p","volume":"275","author":"V Girrbach","year":"2000","journal-title":"The Journal of biological chemistry"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.fob.2014.03.006","article-title":"<italic>Aspergillus nidulans<\/italic> Pmts form heterodimers in all pairwise combinations","volume":"4","author":"T Kriangkripipat","year":"2014","journal-title":"FEBS Open Bio"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"19339","DOI":"10.1074\/jbc.M601091200","article-title":"Physical and functional association of human protein <italic>O<\/italic>-mannosyltransferases 1 and 2","volume":"281","author":"K Akasaka-Manya","year":"2006","journal-title":"J Biol Chem"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1093\/glycob\/7.4.481","article-title":"Protein-<italic>O<\/italic>-glycosylation in yeast: protein-specific mannosyltransferases","volume":"7","author":"M Gentzsch","year":"1997","journal-title":"Glycobiology"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1083\/jcb.145.6.1177","article-title":"<italic>O<\/italic>-Glycosylation of Axl2\/Bud10p by Pmt4p is required for its stability, localization, and function in daughter cells","volume":"145","author":"SL Sanders","year":"1999","journal-title":"The Journal of cell biology"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1091\/mbc.E03-07-0511","article-title":"<italic>O<\/italic>-glycosylation as a sorting determinant for cell surface delivery in yeast","volume":"15","author":"TJ Proszynski","year":"2004","journal-title":"Molecular biology of the cell"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1111\/j.1365-2443.2008.01263.x","article-title":"<italic>O<\/italic>-Mannosylation is required for the solubilization of heterologously expressed human beta-amyloid precursor protein in <italic>Saccharomyces cerevisiae<\/italic>","volume":"14","author":"A Murakami-Sekimata","year":"2009","journal-title":"Genes to Cells"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1128\/MCB.24.1.46-57.2004","article-title":"Aberrant processing of the WSC family and Mid2p cell surface sensors results in cell death of <italic>Saccharomyces cerevisiae O<\/italic>-mannosylation mutants","volume":"24","author":"M Lommel","year":"2004","journal-title":"Mol Cell Biol"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1016\/j.fgb.2012.08.005","article-title":"Mtl1 <italic>O<\/italic>-mannosylation mediated by both Pmt1 and Pmt2 is important for cell survival under oxidative conditions and TOR blockade","volume":"49","author":"MI Petkova","year":"2012","journal-title":"Fungal Genet Biol"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1038\/sj.embor.embor864","article-title":"<italic>O<\/italic>-mannosylation precedes and potentially controls the <italic>N<\/italic>-glycosylation of a yeast cell wall glycoprotein","volume":"4","author":"M Ecker","year":"2003","journal-title":"EMBO reports"},{"key":"ref30","unstructured":"Hutzler J, Schmid M, Bernard T, Henrissat B, Strahl S (2007) Membrane association is a determinant for substrate recognition by <italic>PMT4<\/italic> protein <italic>O<\/italic>-mannosyltransferases. 7827."},{"key":"ref31","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1128\/AEM.26.6.982-990.1973","article-title":"Isolation and characterization of a thermotolerant methanol-utilizing yeast","volume":"26","author":"DW Levine","year":"1973","journal-title":"Applied Microbiology"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1016\/j.femsyr.2005.06.004","article-title":"New yeast expression platforms based on methylotrophic <italic>Hansenula polymorpha<\/italic> and <italic>Pichia pastoris<\/italic> and on dimorphic Arxula adeninivorans and <italic>Yarrowia lipolytica\u2014<\/italic>a comparison","volume":"5","author":"G Gellissen","year":"2005","journal-title":"FEMS yeast research"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1016\/S0958-1669(97)80028-6","article-title":"Production of recombinant proteins by methylotrophic yeasts","volume":"8","author":"CP Hollenberg","year":"1997","journal-title":"Current opinion in biotechnology"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1016\/S0141-0229(00)00173-3","article-title":"The methylotrophic yeast <italic>Hansenula polymorpha<\/italic>: a versatile cell factory","volume":"26","author":"R van Dijk","year":"2000","journal-title":"Enzyme and microbial technology"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1002\/(SICI)1097-0061(19980315)14:4<371::AID-YEA231>3.0.CO;2-1","article-title":"Glycosylation of human alpha 1-antitrypsin in <italic>Saccharomyces cerevisiae<\/italic> and methylotrophic yeasts","volume":"14","author":"HA Kang","year":"1998","journal-title":"Yeast (Chichester, England)"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1093\/glycob\/cwh030","article-title":"Characterization of <italic>N<\/italic>-linked oligosaccharides assembled on secretory recombinant glucose oxidase and cell wall mannoproteins from the methylotrophic yeast <italic>Hansenula polymorpha<\/italic>","volume":"14","author":"MW Kim","year":"2004","journal-title":"Glycobiology"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"6261","DOI":"10.1074\/jbc.M508507200","article-title":"Functional characterization of the <italic>Hansenula polymorpha HOC1<\/italic>, <italic>OCH1<\/italic>, and <italic>OCR1<\/italic> genes as members of the yeast <italic>OCH1<\/italic> mannosyltransferase family involved in protein glycosylation","volume":"281","author":"MW Kim","year":"2006","journal-title":"The Journal of biological chemistry"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1002\/biot.200700252","article-title":"Glycoengineering of the methylotrophic yeast <italic>Hansenula polymorpha<\/italic> for the production of glycoproteins with trimannosyl core <italic>N<\/italic>-glycan by blocking core oligosaccharide assembly","volume":"3","author":"DB Oh","year":"2008","journal-title":"Biotechnology journal"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1007\/s12275-012-2097-2","article-title":"Remodeling of the glycosylation pathway in the methylotrophic yeast <italic>Hansenula polymorpha<\/italic> to produce human hybrid-type <italic>N<\/italic>-glycans","volume":"50","author":"SA Cheon","year":"2012","journal-title":"J Microbiol"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1007\/s11274-012-1197-9","article-title":"Expression of glycoproteins bearing complex human-like glycans with galactose terminal in <italic>Hansenula polymorpha<\/italic>","volume":"29","author":"H Wang","year":"2013","journal-title":"World J Microbiol Biotechnol"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.fgb.2013.08.003","article-title":"Functional and molecular characterization of novel <italic>Hansenula polymorpha<\/italic> genes, <italic>HpPMT5<\/italic> and <italic>HpPMT6<\/italic>, encoding protein <italic>O<\/italic>-mannosyltransferases","volume":"58\u201359","author":"H Kim","year":"2013","journal-title":"Fungal Genet Biol"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1002\/yea.1297","article-title":"Mutation of the protein-<italic>O<\/italic>-mannosyltransferase enhances secretion of the human urokinase-type plasminogen activator in <italic>Hansenula polymorpha<\/italic>","volume":"22","author":"MO Agaphonov","year":"2005","journal-title":"Yeast (Chichester, England)"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"5791","DOI":"10.1093\/nar\/19.20.5791","article-title":"DMSO-enhanced whole cell yeast transformation","volume":"19","author":"J Hill","year":"1991","journal-title":"Nucleic acids research"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1002\/yea.320110407","article-title":"Plasmid reorganization during integrative transformation in <italic>Hansenula polymorpha<\/italic>","volume":"11","author":"AI Bogdanova","year":"1995","journal-title":"Yeast"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1186\/1471-2199-3-15","article-title":"Aggregation and retention of human urokinase type plasminogen activator in the yeast endoplasmic reticulum","volume":"3","author":"MO Agaphonov","year":"2002","journal-title":"BMC Mol Biol"},{"key":"ref46","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1002\/yea.1741","article-title":"A novel kanamycin\/G418 resistance marker for direct selection of transformants in Escherichia coli and different yeast species","volume":"27","author":"M Agaphonov","year":"2010","journal-title":"Yeast"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"4420","DOI":"10.1128\/jb.178.15.4420-4428.1996","article-title":"A novel autonomously replicating sequence (ARS) for multiple integration in the yeast <italic>Hansenula polymorpha<\/italic> DL-1","volume":"178","author":"JH Sohn","year":"1996","journal-title":"J Bacteriol"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1002\/yea.1701","article-title":"New selectable host-marker systems for multiple genetic manipulations based on <italic>TRP1<\/italic>, <italic>MET2<\/italic> and <italic>ADE2<\/italic> in the methylotrophic yeast <italic>Hansenula polymorpha<\/italic>","volume":"26","author":"SA Cheon","year":"2009","journal-title":"Yeast (Chichester, England)"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/yea.1912","article-title":"<italic>HpYPS1<\/italic> and <italic>HpYPS7<\/italic> encode functional aspartyl proteases localized at the cell surface in the thermotolerant methylotrophic yeast <italic>Hansenula polymorpha<\/italic>","volume":"29","author":"MJ Sohn","year":"2012","journal-title":"Yeast (Chichester, England)"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1105\/tpc.007609","article-title":"Genomic analysis of the unfolded protein response in <italic>Arabidopsis<\/italic> shows its connection to important cellular processes","volume":"15","author":"IM Martinez","year":"2003","journal-title":"The Plant Cell"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/j.ymeth.2005.03.001","article-title":"ER stress signaling by regulated splicing: IRE1\/HAC1\/XBP1","volume":"35","author":"SH Back","year":"2005","journal-title":"Methods"},{"key":"ref52","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1111\/j.1365-2958.2011.07537.x","article-title":"Functional and genomic analyses of blocked protein <italic>O<\/italic>-mannosylation in baker&apos;s yeast","volume":"79","author":"J Arroyo","year":"2011","journal-title":"Molecular microbiology"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1091\/mbc.E07-08-0742","article-title":"The sequential activation of the yeast HOG and SLT2 pathways is required for cell survival to cell wall stress","volume":"19","author":"C Bermejo","year":"2008","journal-title":"Mol Biol Cell"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1038\/376702a0","article-title":"Role for the Rho-family GTPase Cdc42 in yeast mating-pheromone signal pathway","volume":"376","author":"MN Simon","year":"1995","journal-title":"Nature"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"3033","DOI":"10.1038\/sj.emboj.7601192","article-title":"Adaptor functions of Cdc42, Ste50, and Sho1 in the yeast osmoregulatory HOG MAPK pathway","volume":"25","author":"K Tatebayashi","year":"2006","journal-title":"EMBO J"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"e100725","DOI":"10.1371\/journal.pone.0100725","article-title":"Novel cysteine-centered sulfur metabolic pathway in the thermotolerant methylotrophic yeast <italic>Hansenula polymorpha<\/italic>","volume":"9","author":"MJ Sohn","year":"2014","journal-title":"PLoS One"},{"key":"ref57","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1016\/0076-6879(91)94055-H","article-title":"Staining of bud scars and other cell wall chitin with calcofluor","volume":"194","author":"JR Pringle","year":"1991","journal-title":"Methods Enzymol"},{"key":"ref58","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1073\/pnas.0307228101","article-title":"Demonstration of mammalian protein <italic>O<\/italic>-mannosyltransferase activity: coexpression of <italic>POMT1<\/italic> and <italic>POMT2<\/italic> required for enzymatic activity","volume":"101","author":"H Manya","year":"2004","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"ref59","doi-asserted-by":"crossref","first-page":"42638","DOI":"10.1074\/jbc.M404900200","article-title":"The twisted abdomen phenotype of Drosophila <italic>POMT1<\/italic> and <italic>POMT2<\/italic> mutants coincides with their heterophilic protein <italic>O<\/italic>-mannosyltransferase activity","volume":"279","author":"T Ichimiya","year":"2004","journal-title":"The Journal of biological chemistry"},{"key":"ref60","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1128\/EC.3.5.1164-1168.2004","article-title":"Pmt-mediated <italic>O<\/italic> mannosylation stabilizes an essential component of the secretory apparatus, Sec20p, in <italic>Candida albicans<\/italic>","volume":"3","author":"Y Weber","year":"2004","journal-title":"Eukaryot Cell"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1093\/jb\/mvm249","article-title":"<italic>O<\/italic>-mannosylation is required for degradation of the endoplasmic reticulum-associated degradation substrate Gas1*p via the ubiquitin\/proteasome pathway in <italic>Saccharomyces cerevisiae<\/italic>","volume":"143","author":"H Hirayama","year":"2008","journal-title":"J Biochem"},{"key":"ref62","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1128\/EC.00182-06","article-title":"Role of protein <italic>O<\/italic>-mannosyltransferase Pmt4 in the morphogenesis and virulence of <italic>Cryptococcus neoformans<\/italic>","volume":"6","author":"GM Olson","year":"2007","journal-title":"Eukaryotic cell"},{"key":"ref63","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1111\/j.1365-2958.2005.04692.x","article-title":"Protein <italic>O<\/italic>-mannosylation is crucial for cell wall integrity, septation and viability in fission yeast","volume":"57","author":"T Willer","year":"2005","journal-title":"Molecular microbiology"},{"key":"ref64","doi-asserted-by":"crossref","first-page":"4721","DOI":"10.1091\/mbc.E07-01-0047","article-title":"Dystroglycan and protein <italic>O<\/italic>-mannosyltransferases 1 and 2 are required to maintain integrity of <italic>Drosophila<\/italic> larval muscles","volume":"18","author":"N Haines","year":"2007","journal-title":"Molecular biology of the cell"},{"key":"ref65","doi-asserted-by":"crossref","first-page":"14126","DOI":"10.1073\/pnas.0405899101","article-title":"Targeted disruption of the Walker-Warburg syndrome gene <italic>POMT1<\/italic> in mouse results in embryonic lethality","volume":"101","author":"T Willer","year":"2004","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"ref66","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1086\/342975","article-title":"Mutations in the <italic>O<\/italic>-mannosyltransferase gene <italic>POMT1<\/italic> give rise to the severe neuronal migration disorder Walker-Warburg syndrome","volume":"71","author":"D Beltran-Valero de Bernabe","year":"2002","journal-title":"American Journal of Human Genetics"},{"key":"ref67","doi-asserted-by":"crossref","first-page":"2725","DOI":"10.1093\/brain\/awm212","article-title":"Refining genotype phenotype correlations in muscular dystrophies with defective glycosylation of dystroglycan","volume":"130","author":"C Godfrey","year":"2007","journal-title":"Brain: a journal of neurology"},{"key":"ref68","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1111\/j.1365-2958.2007.05723.x","article-title":"Transcriptional and physiological adaptation to defective protein-<italic>O<\/italic>-mannosylation in <italic>Candida albicans<\/italic>","volume":"64","author":"PD Cantero","year":"2007","journal-title":"Mol Microbiol"},{"key":"ref69","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1093\/genetics\/130.1.51","article-title":"Genetic analysis of a new mutation conferring cysteine auxotrophy in <italic>Saccharomyces cerevisiae<\/italic>: updating of the sulfur metabolism pathway","volume":"130","author":"H Cherest","year":"1992","journal-title":"Genetics"},{"key":"ref70","doi-asserted-by":"crossref","first-page":"3232","DOI":"10.1073\/pnas.0710412105","article-title":"Engineering of mucin-type human glycoproteins in yeast cells","volume":"105","author":"K Amano","year":"2008","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref71","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1093\/glycob\/cwn008","article-title":"Engineering of a mammalian <italic>O<\/italic>-glycosylation pathway in the yeast <italic>Saccharomyces cerevisiae<\/italic>: production of <italic>O<\/italic>-fucosylated epidermal growth factor domains","volume":"18","author":"Y Chigira","year":"2008","journal-title":"Glycobiology"},{"key":"ref72","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1093\/glycob\/cwt056","article-title":"Production of sialylated <italic>O<\/italic>-linked glycans in <italic>Pichia pastoris<\/italic>","volume":"23","author":"SR Hamilton","year":"2013","journal-title":"Glycobiology"},{"key":"ref73","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1128\/AEM.02106-07","article-title":"Efficient antibody production upon suppression of <italic>O<\/italic> mannosylation in the yeast <italic>Ogataea minuta<\/italic>","volume":"74","author":"K Kuroda","year":"2008","journal-title":"Applied and Environmental Microbiology"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0129914","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,9]],"date-time":"2024-06-09T20:33:45Z","timestamp":1717965225000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0129914"}},"subtitle":[],"editor":[{"given":"Alvaro","family":"Galli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2015,7,2]]},"references-count":73,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2015,7,2]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0129914","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,7,2]]}}}