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Care"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1128\/JCM.01043-10","article-title":"Screening for <italic>Acinetobacter baumannii<\/italic> colonization by use of sponges","volume":"49","author":"Y Doi","year":"2011","journal-title":"J Clin Microbiol"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"2140","DOI":"10.1128\/JCM.00448-12","article-title":"Comparison of swab and sponge methodologies for identification of <italic>Acinetobacter baumannii<\/italic> from the hospital environment","volume":"50","author":"KA Thom","year":"2012","journal-title":"J Clin Microbiol"},{"key":"ref26","author":"WA Link","year":"2010"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1093\/bmb\/ldp038","article-title":"Mathematical modelling of infectious diseases","volume":"92","author":"MJ Keeling","year":"2009","journal-title":"Br Med Bull"},{"key":"ref28","unstructured":"Costa M, de Angelis L. Model selection in hidden Markov models: a simulation study. Quaderni di Dipartimento. 2010; n7: ISSN 1973-9346. <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/amsacta.unibo.it\/2909\/1\/Quaderni_2010_7_FanelliDeAngelis_Model.pdf\" xlink:type=\"simple\">http:\/\/amsacta.unibo.it\/2909\/1\/Quaderni_2010_7_FanelliDeAngelis_Model.pdf<\/ext-link>. Published 2010. Accessed January 15, 2015."},{"key":"ref29","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1080\/10705510701575396","article-title":"Deciding on the number of classes in latent class analysis and growth mixture modeling: a Monte Carlo simulation study","volume":"14","author":"KL Nylund","year":"2007","journal-title":"Struct Equ Modeling"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1086\/502589","article-title":"Modeling transmission of methicillin-resistant <italic>Staphylococcus aureus<\/italic> among patients admitted to a hospital","volume":"26","author":"J Raboud","year":"2005","journal-title":"Infect Control Hosp Epidemiol"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/j.jtbi.2007.08.011","article-title":"Modeling antibiotic resistance in hospitals: the impact of minimizing treatment duration","volume":"249","author":"EM D'Agata","year":"2007","journal-title":"J Theor Biol"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"249","DOI":"10.3102\/10769986022003249","article-title":"Model selection information criteria for non-nested latent class models","volume":"22","author":"TH Lin","year":"1997","journal-title":"J Educ Behav Stat"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0132037","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,10,20]],"date-time":"2018-10-20T09:36:31Z","timestamp":1540028191000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0132037"}},"subtitle":[],"editor":[{"given":"Feng","family":"Gao","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2015,7,1]]},"references-count":32,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2015,7,1]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0132037","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,7,1]]}}}