{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T07:06:00Z","timestamp":1761807960453},"reference-count":33,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2015,8,14]],"date-time":"2015-08-14T00:00:00Z","timestamp":1439510400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0132426","type":"journal-article","created":{"date-parts":[[2015,8,14]],"date-time":"2015-08-14T18:13:21Z","timestamp":1439576001000},"page":"e0132426","update-policy":"http:\/\/dx.doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":27,"title":["Risk of Severe Acute Exacerbation of Chronic HBV Infection Cancer Patients Who Underwent Chemotherapy and Did Not Receive Anti-Viral Prophylaxis"],"prefix":"10.1371","volume":"10","author":[{"given":"Chih-An","family":"Shih","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen-Chi","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hsien-Chung","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin-Shiung","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kwok-Hung","family":"Lai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jui-Ting","family":"Hsu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui-Chun","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ping-I","family":"Hsu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2015,8,14]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"1733","DOI":"10.1056\/NEJM199712113372406","article-title":"Hepatitis B virus infection","volume":"337","author":"WM Lee","year":"1997","journal-title":"N Engl J Med"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"1118","DOI":"10.1056\/NEJMra031087","article-title":"Hepatitis B virus infection-natural history and clinical consequences","volume":"350","author":"D Ganem","year":"2004","journal-title":"N Engl J Med"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1093\/oxfordjournals.aje.a114681","article-title":"Hepatitis B virus infection in Chinese families in Hong Kong","volume":"126","author":"AS Lok","year":"1987","journal-title":"Am J Epidemiol"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1038\/bjc.2011.4","article-title":"Prophylactic use of lamivudine for hepatitis B exacerbation in post-operative breast cancer patients receiving anthracycline-based adjuvant chemotherapy","volume":"104","author":"J Yun","year":"2011","journal-title":"Br J Cancer"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1046\/j.1365-2893.2003.00479.x","article-title":"Lamivudine prophylaxis for prevention of chemotherapy-induced hepatitis B virus reactivation in hepatitis B virus carriers with malignancies","volume":"11","author":"R Idilman","year":"2004","journal-title":"J Viral Hepat"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1200\/JCO.2004.05.161","article-title":"Lamivudine for the prevention of hepatitis B virus reactivation in hepatitis B s-antigen seropositive cancer patients undergoing cytotoxic chemotherapy","volume":"22","author":"W Yeo","year":"2004","journal-title":"J Clin Oncol"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1002\/jmv.10430","article-title":"Hepatitis B virus reactivation in breast cancer patients receiving cytotoxic chemotherapy: a prospective study","volume":"70","author":"W Yeo","year":"2003","journal-title":"J Med Virol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1002\/1096-9071(200011)62:3<299::AID-JMV1>3.0.CO;2-0","article-title":"Frequency of hepatitis B virus reactivation in cancer patients undergoing cytotoxic chemotherapy: a prospective study of 626 patients with identification of risk factors","volume":"62","author":"W Yeo","year":"2000","journal-title":"J Med Virol"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1038\/sj.bjc.6601699","article-title":"Comprehensive analysis of risk factors associating with Hepatitis B virus (HBV) reactivation in cancer patients undergoing cytotoxic chemotherapy","volume":"90","author":"W Yeo","year":"2004","journal-title":"Br J Cancer"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"1320","DOI":"10.1053\/jhep.2003.50220","article-title":"Steroid-free chemotherapy decreases risk of hepatitis B virus (HBV) reactivation in HBV-carriers with lymphoma","volume":"37","author":"AL Cheng","year":"2003","journal-title":"Hepatology"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1016\/j.cgh.2009.06.027","article-title":"Reactivation of hepatitis B with reappearance of hepatitis B surface antigen after chemotherapy and immunosuppression","volume":"7","author":"TN Palmore","year":"2009","journal-title":"Clin Gastroenterol Hepatol"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1111\/j.1440-1746.2012.07280.x","article-title":"Hepatitis B virus reactivation associated with anti-neoplastic therapy","volume":"28","author":"W Yeo","year":"2013","journal-title":"J Gastroenterol Hepatol"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1002\/hep.23190","article-title":"Chronic hepatitis B: Update 2009","volume":"50","author":"AS Lok","year":"2009","journal-title":"Hepatology"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"519","DOI":"10.7326\/0003-4819-148-7-200804010-00008","article-title":"Systematic review: the effect of preventive lamivudine on hepatitis B reactivation during chemotherapy","volume":"148","author":"R Loomba","year":"2008","journal-title":"Ann Intern Med"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"2765","DOI":"10.1200\/JCO.2012.48.5938","article-title":"Randomized controlled trial of entecavir prophylaxis for rituximab-associated hepatitis B virus reactivation in patients with lymphoma and resolved hepatitis B","volume":"31","author":"YH Huang","year":"2013","journal-title":"J Clin Oncol"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.jhep.2008.10.001","article-title":"European Association for the Study of the Liver: EASL clinical practice guidelines: management of chronic hepatitis B","volume":"50","year":"2009","journal-title":"J Hepatol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1200\/JOP.2011.000450","article-title":"Low rates of hepatitis B virus screening at the onset of chemotherapy","volume":"8","author":"JP Hwang","year":"2012","journal-title":"J Oncol Pract"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"32","DOI":"10.3747\/co.v17i6.653","article-title":"Screening for hepatitis B surface antigen before chemotherapy: current practice and opportunities for improvement","volume":"17","author":"R Lee","year":"2010","journal-title":"Curr Oncol"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"923","DOI":"10.3748\/wjg.v19.i6.923","article-title":"Testing for hepatitis B infection in prospective chemotherapy patients: a retrospective study","volume":"19","author":"Y Wang","year":"2013","journal-title":"World J Gastroenterol"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1159\/000183731","article-title":"Oncologists and hepatitis B: a survey to determine current level of awareness and practice of antiviral prophylaxis to prevent reactivation","volume":"55","author":"OS Khokhar","year":"2009","journal-title":"Chemotherapy"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"1931","DOI":"10.1038\/bjc.2013.225","article-title":"Hepatitis B virus reactivation risk varies with different chemotherapy regimens commonly used in solid tumours","volume":"108","author":"WHY Ling","year":"2013","journal-title":"Br J Cancer"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/0016-5085(91)90599-G","article-title":"Reactivation of hepatitis B virus replication in patients receiving cytotoxic therapy. Report of a prospective study","volume":"100","author":"AS Lok","year":"1991","journal-title":"Gastroenterology"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1056\/NEJMoa011795","article-title":"et alCHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large-B-cell lymphoma","volume":"346","author":"B Coiffier","year":"2002","journal-title":"N Engl J Med"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"1742","DOI":"10.1053\/j.gastro.2003.09.026","article-title":"Ealry is superior to deferred preexmptive lamivudine therapy for hepatitis B patients undergoing chemotherapy","volume":"125","author":"GK Lau","year":"2003","journal-title":"Gastroenterology"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1002\/hep.22106","article-title":"A revisit of prophylactic lamivudine for chemotherapy-associated hepatitis B reactivation in non-Hodgkin\u2019s lymphoma. A randomized trial","volume":"47","author":"C Hsu","year":"2008","journal-title":"Hepatology"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1038\/sj.bmt.1700744","article-title":"Hepatic events after bone marrow transplantation in patients with hepatitis B infection: a case controlled study","volume":"19","author":"GK Lau","year":"1997","journal-title":"Bone Marrow Transplant"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1111\/j.1478-3231.2004.0964.x","article-title":"Hepatitis B virus reactivation in breast cancer patients undergoing cytotoxic chemotherapy and the role of preemptive lamivudine administration","volume":"24","author":"MS Dai","year":"2004","journal-title":"Liver Int"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1002\/hep.21513","article-title":"Chronic hepatitis B","volume":"45","author":"AS Lok","year":"2007","journal-title":"Hepatology"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1002\/cncr.24742","article-title":"Hepatitis B virus reactivation and role of antiviral prophylaxis in lymphoma patients with past hepatitis B virus infection who are receiving chemoimmunotherapy","volume":"116","author":"YX Koo","year":"2010","journal-title":"Cancer"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1007\/s00277-009-0806-7","article-title":"Reactivation of hepatitis B virus following rituximab-based regimens: a serious complication in both HBsAg-positive and HBsAg-negative patients","volume":"89","author":"SN Pei","year":"2010","journal-title":"Ann Hematol"},{"key":"ref31","article-title":"Prevention of acute exacerbation of chronic hepatitis B infection in cancer patients receiving chemotherapy in a hepatitis B virus endemic area","author":"PI Hsu","year":"2015","journal-title":"Hepatology"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1111\/j.1478-3231.2007.01618.x","article-title":"Lamivudine prophylaxis is effective in reducing hepatitis B reactivation and reactivation-related mortality in chemotherapy patients: a meta-analysis","volume":"28","author":"LA Martyak","year":"2008","journal-title":"Liver Int"},{"key":"ref33","first-page":"1","article-title":"Recommendations for identification and public health management of persons with chronic hepatitis B virus infection","volume":"57","author":"CM Weinbaum","year":"2008","journal-title":"MMWR Recomm Rep"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0132426","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,10]],"date-time":"2024-06-10T15:07:02Z","timestamp":1718032022000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0132426"}},"subtitle":[],"editor":[{"given":"Yury E","family":"Khudyakov","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2015,8,14]]},"references-count":33,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2015,8,14]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0132426","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,8,14]]}}}