{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T22:37:32Z","timestamp":1648593452545},"reference-count":36,"publisher":"Public Library of Science (PLoS)","issue":"7","license":[{"start":{"date-parts":[[2015,7,20]],"date-time":"2015-07-20T00:00:00Z","timestamp":1437350400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0133126","type":"journal-article","created":{"date-parts":[[2015,7,20]],"date-time":"2015-07-20T17:55:00Z","timestamp":1437414900000},"page":"e0133126","update-policy":"http:\/\/dx.doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":3,"title":["Human Infant Memory B Cell and CD4+ T Cell Responses to HibMenCY-TT Glyco-Conjugate Vaccine"],"prefix":"10.1371","volume":"10","author":[{"given":"Angela","family":"Fuery","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter C.","family":"Richmond","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew J.","family":"Currie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2015,7,20]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"S58","DOI":"10.1016\/S0264-410X(01)00299-7","article-title":"Planning, registration, and implementation of an immunisation campaign against meningococcal serogroup C disease in the UK: a success story","volume":"20","author":"E Miller","year":"2002","journal-title":"Vaccine"},{"issue":"6","key":"ref2","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1136\/adc.86.6.396","article-title":"The UK Hib vaccine experience","volume":"86","author":"PT Heath","year":"2002","journal-title":"Arch Dis Child"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/S0140-6736(04)16725-1","article-title":"Effectiveness of meningococcal serogroup C conjugate vaccine 4 years after introduction","volume":"364","author":"C Trotter","year":"2004","journal-title":"Lancet"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1038\/40540","article-title":"Lifetime of plasma cells in the bone marrow","volume":"388","author":"R Manz","year":"1997","journal-title":"Nature"},{"issue":"3","key":"ref5","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/S1074-7613(00)80541-5","article-title":"Humoral immunity due to long-lived plasma cells","volume":"8","author":"MK Slifka","year":"1998","journal-title":"Immunity"},{"issue":"1","key":"ref6","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1111\/j.1365-2567.2008.02934.x","article-title":"Plasma and memory B-cell kinetics in infants following a primary schedule of CRM197-conjugated serogroup C meningococcal polysaccharide vaccine","volume":"127","author":"D Kelly","year":"2009","journal-title":"Immunology"},{"issue":"4","key":"ref7","doi-asserted-by":"crossref","first-page":"2165","DOI":"10.4049\/jimmunol.180.4.2165","article-title":"The Magnitude of the Antibody and Memory B Cell Responses during Priming with a Protein-Polysaccharide Conjugate Vaccine in Human Infants Is Associated with the Persistence of Antibody and the Intensity of Booster Response","volume":"180","author":"G Blanchard-Rohner","year":"2008","journal-title":"J Immunol"},{"issue":"9","key":"ref8","doi-asserted-by":"crossref","first-page":"2097","DOI":"10.1016\/j.vaccine.2009.12.039","article-title":"Meningococcal serogroup C polysaccharide specific memory B cells, directly enumerated by labeled polysaccharide, are not affected by age at vaccination","volume":"28","author":"M Henneken","year":"2010","journal-title":"Vaccine"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"2642","DOI":"10.1182\/blood-2006-01-009282","article-title":"CRM-197-conjugated serogroup C meningococcal capsular polysaccharide, but not the native polysaccharide, induces persistent antigen-specific memory B cells","volume":"108","author":"D Kelly","year":"2006","journal-title":"Blood"},{"issue":"5","key":"ref10","doi-asserted-by":"crossref","first-page":"2673","DOI":"10.4049\/jimmunol.1200451","article-title":"B Cell Memory to a Serogroup C Meningococcal Conjugate Vaccine in Childhood and Response to Booster: Little Association with Serum IgG Antibody","volume":"189","author":"KP Perrett","year":"2012","journal-title":"J Immunol"},{"issue":"20","key":"ref11","doi-asserted-by":"crossref","first-page":"2441","DOI":"10.1016\/j.vaccine.2013.03.036","article-title":"The B-cell response to a primary and booster course of MenACWY-CRM197 vaccine administered at 2, 4 and 12 months of age","volume":"31","author":"G Blanchard-Rohner","year":"2013","journal-title":"Vaccine"},{"issue":"7","key":"ref12","doi-asserted-by":"crossref","first-page":"e101672","DOI":"10.1371\/journal.pone.0101672","article-title":"Evaluation of the induction of immune memory following infant immunisation with serogroup C Neisseria meningitidis conjugate vaccines\u2014exploratory analyses within a randomised controlled trial","volume":"9","author":"A Khatami","year":"2014","journal-title":"PLoS One"},{"issue":"1","key":"ref13","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1128\/CVI.00384-09","article-title":"Kinetics of Antibody Persistence following Administration of a Combination Meningococcal Serogroup C and Haemophilus influenzae Type b Conjugate Vaccine in Healthy Infants in the United Kingdom Primed with a Monovalent Meningococcal Serogroup C Vaccine","volume":"17","author":"R Borrow","year":"2010","journal-title":"Clin Vaccine Immunol"},{"issue":"18","key":"ref14","doi-asserted-by":"crossref","first-page":"2831","DOI":"10.1016\/j.vaccine.2012.02.046","article-title":"Persistence of the immune response at 5 years of age following infant immunisation with investigational quadrivalent MenACWY conjugate vaccine formulations","volume":"30","author":"A Khatami","year":"2012","journal-title":"Vaccine"},{"issue":"3","key":"ref15","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1097\/INF.0b013e3181fcb2bf","article-title":"Immunogenicity and Safety of an Investigational Combined Haemophilus influenzae Type B-Neisseria meningitidis Serogroups C and Y-Tetanus Toxoid Conjugate Vaccine","volume":"30","author":"T Nolan","year":"2011","journal-title":"Pediatr Infect Dis J"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1016\/j.vaccine.2008.12.046","article-title":"Neonatal pneumococcal conjugate vaccine immunization primes T cells for preferential Th2 cytokine expression: A randomized controlled trial in Papua New Guinea","volume":"27","author":"A van den Biggelaar","year":"2009","journal-title":"Vaccine"},{"issue":"3","key":"ref17","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1111\/j.1365-2567.2006.02436.x","article-title":"The kinetics and phenotype of the human B-cell response following immunization with a heptavalent pneumococcal-CRM197 conjugate vaccine","volume":"119","author":"E Clutterbuck","year":"2006","journal-title":"Immunology"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1086\/317646","article-title":"Ability of 3 Different Meningococcal C Conjugate Vaccines to Induce Immunologic Memory after a Single Dose in UK Toddlers","volume":"183","author":"P Richmond","year":"2001","journal-title":"J Infect Dis"},{"issue":"51","key":"ref19","doi-asserted-by":"crossref","first-page":"8487","DOI":"10.1016\/j.vaccine.2007.10.013","article-title":"A novel combined Haemophilus influenzae type b-Neisseria meningitidis serogroups C and Y-tetanus-toxoid conjugate vaccine is immunogenic and induces immune memory when co-administered with DTPa-HBV-IPV and conjugate pneumococcal vaccines in infants","volume":"25","author":"T Nolan","year":"2007","journal-title":"Vaccine"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1086\/344324","article-title":"Antibody Persistence and Immunological Memory at Age 4 Years after Meningococcal Group C Conjugate Vaccination in Children in the United Kingdom","volume":"186","author":"R Borrow","year":"2002","journal-title":"J Infect Dis"},{"issue":"5258","key":"ref21","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1126\/science.272.5258.54","article-title":"Immunological memory and protective immunity: Understanding their relation","volume":"272","author":"R Ahmed","year":"1996","journal-title":"Science"},{"issue":"9","key":"ref22","doi-asserted-by":"crossref","first-page":"5514","DOI":"10.4049\/jimmunol.1002932","article-title":"Circulating Human Antibody-Secreting Cells during Vaccinations and Respiratory Viral Infections Are Characterized by High Specificity and Lack of Bystander Effect","volume":"186","author":"F Lee","year":"2011","journal-title":"J Immunol"},{"issue":"2","key":"ref23","doi-asserted-by":"crossref","first-page":"686","DOI":"10.4049\/jimmunol.170.2.686","article-title":"Intrinsic differences in the proliferation of naive and memory human B cells as a mechanism for enhanced secondary immune responses","volume":"170","author":"SG Tangye","year":"2003","journal-title":"J Immunol"},{"issue":"11","key":"ref24","doi-asserted-by":"crossref","first-page":"4500","DOI":"10.1182\/blood-2002-11-3569","article-title":"A role for Toll-like receptors in acquired immunity: up-regulation of TLR9 by BCR triggering in naive B cells and constitutive expression in memory B cells","volume":"101","author":"N Bernasconi","year":"2003","journal-title":"Blood"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"2199","DOI":"10.1126\/science.1076071","article-title":"Maintenance of Serological Memory by Polyclonal Activation of Human Memory B Cells","volume":"298","author":"N Bernasconi","year":"2002","journal-title":"Science"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1038\/nri2494","article-title":"Maintaining protection against invasive bacteria with protein-polysaccharide conjugate vaccines","volume":"9","author":"A Pollard","year":"2009","journal-title":"Nat Rev Immunol"},{"issue":"4","key":"ref27","doi-asserted-by":"crossref","first-page":"1406","DOI":"10.1002\/(SICI)1521-4141(199904)29:04<1406::AID-IMMU1406>3.0.CO;2-P","article-title":"Correlation analysis between frequencies of circulating antigen-specific IgG-bearing memory B cells and serum titers of antigen-specific IgG","volume":"29","author":"H Leyendeckers","year":"1999","journal-title":"Eur J Immunol"},{"issue":"1","key":"ref28","doi-asserted-by":"crossref","first-page":"165","DOI":"10.4049\/jimmunol.176.1.165","article-title":"Reduced ability of neonatal and early-life bone marrow stromal cells to support plasmablast survival","volume":"176","author":"M Pihlgren","year":"2006","journal-title":"J Immunol"},{"issue":"3","key":"ref29","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1002\/1521-4141(200103)31:3<939::AID-IMMU939>3.0.CO;2-I","article-title":"Delayed and deficient establishment of the long-term bone marrow plasma cell pool during early life","volume":"31","author":"M Pihlgren","year":"2001","journal-title":"Eur J Immunol"},{"issue":"8","key":"ref30","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1086\/651418","article-title":"Cellular CD4 T Cell Responses to the Diphtheria-Derived Carrier Protein of Conjugated Pneumococcal Vaccine and Antibody Response to Pneumococcal Vaccination in HIV-Infected Adults","volume":"50","author":"C Rabian","year":"2010","journal-title":"Clin Infect Dis"},{"issue":"12","key":"ref31","doi-asserted-by":"crossref","first-page":"6071","DOI":"10.4049\/jimmunol.1203254","article-title":"Polysaccharide-Specific Memory B Cells Generated by Conjugate Vaccines in Humans Conform to the CD27(+)IgG(+) Isotype-Switched Memory B Cell Phenotype and Require Contact-Dependent Signals from Bystander T Cells Activated by Bacterial Proteins To Differentiate into Plasma Cells","volume":"191","author":"ET Clarke","year":"2013","journal-title":"J Immunol"},{"issue":"4","key":"ref32","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1038\/nri2274","article-title":"T-cell quality in memory and protection: implications for vaccine design","volume":"8","author":"RA Seder","year":"2008","journal-title":"Nat Rev Immunol"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1002\/eji.200535102","article-title":"Early life T cell responses to pneumococcal conjugates increase with age and determine the polysaccharide-specific antibody response and protective efficacy","volume":"36","author":"H Jakobsen","year":"2006","journal-title":"Eur J Immunol"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"1629","DOI":"10.1086\/374785","article-title":"Significant Variation in Serotype-Specific Immunogenicity of the Seven-Valent Streptococcus pneumoniae Capsular Polysaccharide-CRM197 Conjugate Vaccine Occurs Despite Vigorous T Cell Help Induced by the Carrier Protein","volume":"187","author":"K Kamboj","year":"2003","journal-title":"J Infect Dis"},{"issue":"9\u201310","key":"ref35","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1016\/S0264-410X(00)00314-5","article-title":"Serotype of Streptococcus pneumoniae capsular polysaccharide can modify the Th1\/Th2 cytokine profile and IgG subclass response to pneumococal-CRM197 conjugate vaccines in a murine model","volume":"19","author":"F Mawas","year":"2000","journal-title":"Vaccine"},{"issue":"9","key":"ref36","doi-asserted-by":"crossref","first-page":"4862","DOI":"10.1128\/IAI.67.9.4862-4869.1999","article-title":"B- and T-cell immune responses to pneumococcal conjugate vaccines: Divergence between carrier- and polysaccharide-specific immunogenicity","volume":"67","author":"TL McCool","year":"1999","journal-title":"Infect Immun"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0133126","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,5]],"date-time":"2020-09-05T07:56:18Z","timestamp":1599292578000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0133126"}},"subtitle":[],"editor":[{"given":"Ray","family":"Borrow","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2015,7,20]]},"references-count":36,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2015,7,20]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0133126","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,7,20]]}}}