{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T13:27:28Z","timestamp":1791293248193,"version":"4.1.0"},"reference-count":27,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2015,8,26]],"date-time":"2015-08-26T00:00:00Z","timestamp":1440547200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0136191","type":"journal-article","created":{"date-parts":[[2015,8,26]],"date-time":"2015-08-26T14:00:07Z","timestamp":1440597607000},"page":"e0136191","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":33,"title":["Characterization of Rhinitis According to the Asthma Status in Adults Using an Unsupervised Approach in the EGEA Study"],"prefix":"10.1371","volume":"10","author":[{"given":"Emilie","family":"Burte","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean","family":"Bousquet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rapha\u00eblle","family":"Varraso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fr\u00e9d\u00e9ric","family":"Gormand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jocelyne","family":"Just","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R\u00e9gis","family":"Matran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Pin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Val\u00e9rie","family":"Siroux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B\u00e9n\u00e9dicte","family":"Jacquemin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel","family":"Nadif","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2015,8,26]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1111\/j.1398-9995.2007.01620.x","article-title":"Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA2LEN and AllerGen)","author":"J Bousquet","year":"2008","journal-title":"Allergy: European Journal of Allergy and Clinical Immunology"},{"issue":"10","key":"ref2","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1111\/j.1398-9995.2008.01824.x","article-title":"Geographical distribution of atopic rhinitis in the European Community Respiratory Health Survey I","volume":"63","author":"PJ Bousquet","year":"2008","journal-title":"Allergy Eur J Allergy Clin Immunol"},{"issue":"2","key":"ref3","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1111\/j.1365-2222.2011.03891.x","article-title":"Prevalence and diversity of allergic rhinitis in regions of the world beyond Europe and North America","volume":"42","author":"CH Katelaris","year":"2012","journal-title":"Clin Exp Allergy"},{"issue":"5","key":"ref4","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1111\/j.1398-9995.2010.02534.x","article-title":"MeDALL (Mechanisms of the Development of ALLergy): an integrated approach from phenotypes to systems medicine","volume":"66","author":"J Bousquet","year":"2011","journal-title":"Allergy"},{"issue":"2","key":"ref5","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/S2213-2600(13)70277-7","article-title":"Comorbidity of eczema, rhinitis, and asthma in IgE-sensitised and non-IgE-sensitised children in MeDALL: a population-based cohort study","volume":"2","author":"M Pinart","year":"2014","journal-title":"Lancet Respir Med"},{"issue":"2","key":"ref6","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1007\/s11882-012-0331-y","article-title":"Comparative analysis of allergic rhinitis in children and adults","volume":"13","author":"A Izquierdo-Dom\u00ednguez","year":"2013","journal-title":"Curr Allergy Asthma Rep"},{"issue":"2","key":"ref7","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1183\/09031936.00120810","article-title":"Identifying adult asthma phenotypes using a clustering approach","volume":"38","author":"V Siroux","year":"2011","journal-title":"Eur Respir J"},{"issue":"3","key":"ref8","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1007\/s11882-012-0254-7","article-title":"Recent advances in the epidemiologic investigation of risk factors for asthma: a review of the 2011 literature","volume":"12","author":"JM Ant\u00f3","year":"2012","journal-title":"Curr Allergy Asthma Rep"},{"issue":"3","key":"ref9","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1183\/09031936.00175109","article-title":"Clinical COPD phenotypes: a novel approach using principal component and cluster analyses","volume":"36","author":"P-R Burgel","year":"2010","journal-title":"Eur Respir J"},{"issue":"4","key":"ref10","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1183\/09031936.00174408","article-title":"Distinct clinical phenotypes of airways disease defined by cluster analysis","volume":"34","author":"M Weatherall","year":"2009","journal-title":"Eur Respir J"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.jaci.2014.06.017","article-title":"Identifying the heterogeneity of young adult rhinitis through cluster analysis in the Isle of Wight birth cohort","author":"RJ Kurukulaaratchy","year":"2015","journal-title":"Journal of Allergy and Clinical Immunology"},{"key":"ref12","first-page":"17","article-title":"EGEA\u2014descriptive characteristics","volume":"29","author":"F Kauffmann","year":"1999","journal-title":"Clin Exp Allergy"},{"issue":"4","key":"ref13","doi-asserted-by":"crossref","first-page":"S123","DOI":"10.1164\/ajrccm.156.4.12tac9","article-title":"Epidemiological study of the genetics and environment of asthma, bronchial hyperresponsiveness, and atopy: phenotype issues","volume":"156","author":"F Kauffmann","year":"1997","journal-title":"Am J Respir Crit Care Med"},{"issue":"4","key":"ref14","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/j.jaci.2009.06.010","article-title":"Phenotypic determinants of uncontrolled asthma","volume":"124","author":"V Siroux","year":"2009","journal-title":"J Allergy Clin Immunol"},{"issue":"9643","key":"ref15","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1016\/S0140-6736(08)61446-4","article-title":"Rhinitis and onset of asthma: a longitudinal population-based study","volume":"372","author":"R Shaaban","year":"2008","journal-title":"Lancet"},{"issue":"8","key":"ref16","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1093\/comjnl\/41.8.578","article-title":"How Many Clusters? Which Clustering Method? Answers Via Model-Based Cluster Analysis","volume":"41","author":"C Fraley","year":"1998","journal-title":"Comput J"},{"key":"ref17","doi-asserted-by":"crossref","unstructured":"McLachlan GJ, Peel DA. Finite mixture models. 2000.","DOI":"10.1002\/0471721182"},{"issue":"3","key":"ref18","doi-asserted-by":"crossref","first-page":"148","DOI":"10.4168\/aair.2011.3.3.148","article-title":"Management of Rhinitis: Allergic and Non-Allergic","volume":"3","author":"NP Tran","year":"2011","journal-title":"Allergy, Asthma Immunol Res"},{"issue":"3","key":"ref19","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/j.iac.2011.05.011","article-title":"Other causes of rhinitis: mixed rhinitis, rhinitis medicamentosa, hormonal rhinitis, rhinitis of the elderly, and gustatory rhinitis","volume":"31","author":"RA Settipane","year":"2011","journal-title":"Immunol Allergy Clin North Am"},{"issue":"4","key":"ref20","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1097\/ACI.0b013e3283630cd8","article-title":"Nonallergic rhinitis: therapeutic options","volume":"13","author":"J a Bernstein","year":"2013","journal-title":"Curr Opin Allergy Clin Immunol"},{"issue":"3","key":"ref21","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1159\/000320050","article-title":"Differences and similarities between allergic and nonallergic rhinitis in a large sample of adult patients with rhinitis symptoms","volume":"155","author":"G Di Lorenzo","year":"2011","journal-title":"Int Arch Allergy Immunol"},{"issue":"5","key":"ref22","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1080\/02770900902849897","article-title":"Allergic and nonallergic rhinitis: can we find the differences\/similarities between the two pictures?","volume":"46","author":"F Kalpaklioglu a","year":"2009","journal-title":"J Asthma"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1111\/j.1398-9995.2006.01054.x","article-title":"Prevalence, classification and perception of allergic and nonallergic rhinitis in Belgium","volume":"61","author":"C Bachert","year":"2006","journal-title":"Allergy"},{"issue":"9","key":"ref24","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1111\/j.1398-9995.2007.01355.x","article-title":"Differences between allergic and nonallergic rhinitis in a large sample of adolescents and adults","volume":"62","author":"E Molgaard","year":"2007","journal-title":"Allergy"},{"issue":"6","key":"ref25","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1002\/alr.21312","article-title":"Predictive factors to differentiate between allergic and nonallergic rhinitis in children","volume":"4","author":"E Topal","year":"2014","journal-title":"Int Forum Allergy Rhinol"},{"issue":"9","key":"ref26","first-page":"1583","article-title":"Diagnosing rhinitis: allergic vs. nonallergic","volume":"73","author":"DM Quillen","year":"2006","journal-title":"Am Fam Physician"},{"issue":"6","key":"ref27","doi-asserted-by":"crossref","first-page":"457","DOI":"10.2500\/ajra.2013.27.3983","article-title":"Characterizing rhinitis subtypes","volume":"27","author":"JA Bernstein","year":"2013","journal-title":"Am J Rhinol Allergy"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0136191","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,29]],"date-time":"2019-08-29T17:40:18Z","timestamp":1567100418000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0136191"}},"subtitle":[],"editor":[{"given":"Zheng","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2015,8,26]]},"references-count":27,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2015,8,26]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0136191","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,8,26]]}}}