{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,12]],"date-time":"2026-04-12T16:20:17Z","timestamp":1776010817102,"version":"3.50.1"},"reference-count":12,"publisher":"Public Library of Science (PLoS)","issue":"8","license":[{"start":{"date-parts":[[2015,8,31]],"date-time":"2015-08-31T00:00:00Z","timestamp":1440979200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0136684","type":"journal-article","created":{"date-parts":[[2015,8,31]],"date-time":"2015-08-31T17:45:30Z","timestamp":1441043130000},"page":"e0136684","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":6,"title":["Novel Alternative Splice Variants of Mouse Cdk5rap2"],"prefix":"10.1371","volume":"10","author":[{"given":"Nadine","family":"Kraemer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lina","family":"Issa-Jahns","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerda","family":"Neubert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ethiraj","family":"Ravindran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shyamala","family":"Mani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olaf","family":"Ninnemann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela M.","family":"Kaindl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"340","published-online":{"date-parts":[[2015,8,31]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1086\/302777","article-title":"A third novel locus for primary autosomal recessive microcephaly maps to chromosome 9q34","volume":"66","author":"L Moynihan","year":"2000","journal-title":"Am J Hum Genet"},{"key":"ref2","first-page":"353","article-title":"A centrosomal mechanism involving CDK5RAP2 and CENPJ controls brain size","volume":"37","author":"J Bond","year":"2005","journal-title":"NatGenet"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1186\/1750-1172-6-39","article-title":"Autosomal Recessive Primary Microcephaly (MCPH): clinical manifestations, genetic heterogeneity and mutation continuum","volume":"6","author":"S Mahmood","year":"2011","journal-title":"Orphanet J Rare Dis"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.pneurobio.2009.11.002","article-title":"Many roads lead to primary autosomal recessive microcephaly","volume":"90","author":"AM Kaindl","year":"2010","journal-title":"Prog Neurobiol"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/j.tig.2009.09.011","article-title":"Primary microcephaly: do all roads lead to Rome?","volume":"25","author":"GK Thornton","year":"2009","journal-title":"Trends Genet"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"1907","DOI":"10.1242\/dev.040410","article-title":"Cdk5rap2 regulates centrosome function and chromosome segregation in neuronal progenitors","volume":"137","author":"SB Lizarraga","year":"2010","journal-title":"Development"},{"key":"ref7","article-title":"Loss of CDK5RAP2 affects neural but not non-neural mESC differentiation into cardiomyocytes","author":"N Kraemer","year":"2015","journal-title":"Cell Cycle"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1016\/j.devcel.2010.05.017","article-title":"CDK5RAP2 regulates centriole engagement and cohesion in mice","volume":"18","author":"JA Barrera","year":"2010","journal-title":"Dev Cell"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1002\/1526-968X(200011\/12)28:3\/4<106::AID-GENE30>3.0.CO;2-T","article-title":"Widespread recombinase expression using FLPeR (flipper) mice","volume":"28","author":"FW Farley","year":"2000","journal-title":"Genesis"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1016\/S1472-6483(10)62085-8","article-title":"Micromanipulation of the human oocyte","volume":"7","author":"ZP Nagy","year":"2003","journal-title":"Reprod Biomed Online"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"2245","DOI":"10.1093\/cercor\/bhs212","article-title":"CDK5RAP2 expression during murine and human brain development correlates with pathology in primary autosomal recessive microcephaly","volume":"23","author":"L Issa","year":"2013","journal-title":"Cereb Cortex"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1091\/mbc.E07-04-0371","article-title":"CDK5RAP2 is a pericentriolar protein that functions in centrosomal attachment of the gamma-tubulin ring complex","volume":"19","author":"KW Fong","year":"2008","journal-title":"Mol Biol Cell"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0136684","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,10,24]],"date-time":"2018-10-24T01:48:57Z","timestamp":1540345737000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0136684"}},"subtitle":[],"editor":[{"given":"Emanuele","family":"Buratti","sequence":"first","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2015,8,31]]},"references-count":12,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2015,8,31]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0136684","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,8,31]]}}}