{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T02:00:39Z","timestamp":1783562439253,"version":"3.55.0"},"reference-count":27,"publisher":"Public Library of Science (PLoS)","issue":"9","license":[{"start":{"date-parts":[[2015,9,11]],"date-time":"2015-09-11T00:00:00Z","timestamp":1441929600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0137476","type":"journal-article","created":{"date-parts":[[2015,9,11]],"date-time":"2015-09-11T17:52:48Z","timestamp":1441993968000},"page":"e0137476","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":13,"title":["Cancer-Testis Antigen Expression in Serous Endometrial Cancer with Loss of X Chromosome Inactivation"],"prefix":"10.1371","volume":"10","author":[{"given":"Jun","family":"Kang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hee Jin","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sun-Young","family":"Jun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eun Su","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lee-so","family":"Maeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2015,9,11]]},"reference":[{"issue":"9","key":"ref1","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1038\/nrclinonc.2014.111","article-title":"Therapeutic vaccines for cancer: an overview of clinical trials","volume":"11","author":"I Melero","year":"2014","journal-title":"Nature reviews Clinical oncology"},{"issue":"4","key":"ref2","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1038\/nrc3239","article-title":"The blockade of immune checkpoints in cancer immunotherapy","volume":"12","author":"DM Pardoll","year":"2012","journal-title":"Nature reviews Cancer"},{"issue":"19","key":"ref3","doi-asserted-by":"crossref","first-page":"2388","DOI":"10.1200\/JCO.2012.44.3762","article-title":"Predictive gene signature in MAGE-A3 antigen-specific cancer immunotherapy","volume":"31","author":"F Ulloa-Montoya","year":"2013","journal-title":"Journal of clinical oncology: official journal of the American Society of Clinical Oncology"},{"issue":"19","key":"ref4","doi-asserted-by":"crossref","first-page":"2396","DOI":"10.1200\/JCO.2012.43.7103","article-title":"Adjuvant MAGE-A3 immunotherapy in resected non-small-cell lung cancer: phase II randomized study results","volume":"31","author":"J Vansteenkiste","year":"2013","journal-title":"Journal of clinical oncology: official journal of the American Society of Clinical Oncology"},{"issue":"2","key":"ref5","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/S1074-7613(95)80053-0","article-title":"BAGE: a new gene encoding an antigen recognized on human melanomas by cytolytic T lymphocytes","volume":"2","author":"P Boel","year":"1995","journal-title":"Immunity"},{"issue":"28","key":"ref6","doi-asserted-by":"crossref","first-page":"17618","DOI":"10.1074\/jbc.273.28.17618","article-title":"Isolation and characterization of PAGE-1 and GAGE-7. New genes expressed in the LNCaP prostate cancer progression model that share homology with melanoma-associated antigens","volume":"273","author":"ME Chen","year":"1998","journal-title":"The Journal of biological chemistry"},{"issue":"13","key":"ref7","first-page":"3157","article-title":"Characterization of the GAGE genes that are expressed in various human cancers and in normal testis","volume":"59","author":"O De Backer","year":"1999","journal-title":"Cancer research"},{"issue":"5","key":"ref8","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1007\/BF01246677","article-title":"Structure, chromosomal localization, and expression of 12 genes of the MAGE family","volume":"40","author":"E De Plaen","year":"1994","journal-title":"Immunogenetics"},{"issue":"20","key":"ref9","first-page":"4766","article-title":"The SSX-2 gene, which is involved in the t(X;18) translocation of synovial sarcomas, codes for the human tumor antigen HOM-MEL-40","volume":"56","author":"O Tureci","year":"1996","journal-title":"Cancer research"},{"issue":"5038","key":"ref10","doi-asserted-by":"crossref","first-page":"1643","DOI":"10.1126\/science.1840703","article-title":"A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma","volume":"254","author":"P van der Bruggen","year":"1991","journal-title":"Science"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1146\/annurev-pharmtox-011112-140326","article-title":"Cause and consequence of cancer\/testis antigen activation in cancer","volume":"54","author":"AW Whitehurst","year":"2014","journal-title":"Annual review of pharmacology and toxicology"},{"issue":"7","key":"ref12","first-page":"1766","article-title":"Expression of the MAGE-1 tumor antigen is up-regulated by the demethylating agent 5-aza-2&apos;-deoxycytidine","volume":"54","author":"J Weber","year":"1994","journal-title":"Cancer research"},{"issue":"15","key":"ref13","doi-asserted-by":"crossref","first-page":"10118","DOI":"10.1074\/jbc.M510469200","article-title":"Transient down-regulation of DNMT1 methyltransferase leads to activation and stable hypomethylation of MAGE-A1 in melanoma cells","volume":"281","author":"A Loriot","year":"2006","journal-title":"The Journal of biological chemistry"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1101\/sqb.2005.70.045","article-title":"Abnormalities of the inactive X chromosome are a common feature of BRCA1 mutant and sporadic basal-like breast cancer","volume":"70","author":"S Ganesan","year":"2005","journal-title":"Cold Spring Harbor symposia on quantitative biology"},{"issue":"3","key":"ref15","doi-asserted-by":"crossref","first-page":"e0118927","DOI":"10.1371\/journal.pone.0118927","article-title":"Dysregulation of x chromosome inactivation in high grade ovarian serous adenocarcinoma","volume":"10","author":"J Kang","year":"2015","journal-title":"PloS one"},{"issue":"8","key":"ref16","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1038\/nrc2172","article-title":"The disappearing Barr body in breast and ovarian cancers","volume":"7","author":"GJ Pageau","year":"2007","journal-title":"Nature reviews Cancer"},{"issue":"2","key":"ref17","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.ccr.2006.01.013","article-title":"X chromosomal abnormalities in basal-like human breast cancer","volume":"9","author":"AL Richardson","year":"2006","journal-title":"Cancer cell"},{"issue":"4","key":"ref18","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1016\/j.cell.2013.01.034","article-title":"Xist RNA is a potent suppressor of hematologic cancer in mice","volume":"152","author":"E Yildirim","year":"2013","journal-title":"Cell"},{"issue":"7447","key":"ref19","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1038\/nature12113","article-title":"Integrated genomic characterization of endometrial carcinoma","volume":"497","author":"C Kandoth","year":"2013","journal-title":"Nature"},{"key":"ref20","first-page":"228","article-title":"A dualistic model for endometrial carcinogenesis based on immunohistochemical and molecular genetic analyses","volume":"81","author":"SF Lax","year":"1997","journal-title":"Verhandlungen der Deutschen Gesellschaft fur Pathologie"},{"key":"ref21","unstructured":"Jacobsen A. cgdsr: R-Based API for accessing the MSKCC Cancer Genomics Data Server (CGDS). 2013. Available from: <ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/CRAN.R-project.org\/package=cgdsr\" xlink:type=\"simple\">http:\/\/CRAN.R-project.org\/package=cgdsr<\/ext-link>."},{"key":"ref22","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1186\/1471-2105-12-323","article-title":"RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome","volume":"12","author":"B Li","year":"2011","journal-title":"BMC bioinformatics"},{"issue":"1","key":"ref23","first-page":"24","article-title":"X Chromosome: X Inactivation","volume":"1","author":"J Ahn","year":"2008","journal-title":"Nature Education"},{"issue":"7407","key":"ref24","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1038\/nature11252","article-title":"Comprehensive molecular characterization of human colon and rectal cancer","volume":"487","year":"2012","journal-title":"Nature"},{"issue":"7536","key":"ref25","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1038\/nature14129","article-title":"Comprehensive genomic characterization of head and neck squamous cell carcinomas","volume":"517","year":"2015","journal-title":"Nature"},{"issue":"7417","key":"ref26","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1038\/nature11404","article-title":"Comprehensive genomic characterization of squamous cell lung cancers","volume":"489","year":"2012","journal-title":"Nature"},{"issue":"7511","key":"ref27","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1038\/nature13385","article-title":"Comprehensive molecular profiling of lung adenocarcinoma","volume":"511","year":"2014","journal-title":"Nature"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0137476","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,10,20]],"date-time":"2018-10-20T12:26:48Z","timestamp":1540038408000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0137476"}},"subtitle":[],"editor":[{"given":"Riccardo","family":"Dolcetti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2015,9,11]]},"references-count":27,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2015,9,11]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0137476","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,9,11]]}}}