{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T23:47:15Z","timestamp":1792799235996,"version":"4.5.0"},"reference-count":33,"publisher":"Public Library of Science (PLoS)","issue":"9","license":[{"start":{"date-parts":[[2015,9,16]],"date-time":"2015-09-16T00:00:00Z","timestamp":1442361600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0137912","type":"journal-article","created":{"date-parts":[[2015,9,16]],"date-time":"2015-09-16T20:09:02Z","timestamp":1442434142000},"page":"e0137912","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":33,"title":["Relationship between Body Mass Composition, Bone Mineral Density, Skin Fibrosis and 25(OH) Vitamin D Serum Levels in Systemic Sclerosis"],"prefix":"10.1371","volume":"10","author":[{"given":"Addolorata","family":"Corrado","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ripalta","family":"Colia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angiola","family":"Mele","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valeria","family":"Di Bello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonello","family":"Trotta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Neve","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco Paolo","family":"Cantatore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2015,9,16]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1007\/s12016-010-8198-y","article-title":"Diagnosis and classification of systemic sclerosis","volume":"40","author":"E Hachulla","year":"2011","journal-title":"Clin Rev Allergy Immunol"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1136\/ard.2003.011064","article-title":"Bone mineral density in patients with systemic sclerosis","volume":"63","author":"B Frediani","year":"2004","journal-title":"Ann Rheum Dis"},{"key":"ref3","first-page":"1","article-title":"Bone mineral density in scleroderma","volume":"37","author":"L Carbone","year":"1999","journal-title":"Rheumatology (Oxford)"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1093\/ajcn\/84.1.18","article-title":"Estimation of optimal serum concentrations of 25-hydroxyvitamin D for multiple health outcomes","volume":"84","author":"HA Bischoff-Ferrari","year":"2006","journal-title":"Am J Clin Nutr"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1016\/j.autrev.2013.02.004","article-title":"Vitamin D effects on musculoskeletal health, immunity, autoimmunity, cardiovascular disease, cancer, fertility, pregnancy, dementia and mortality-a review of recent evidence","volume":"12","author":"P Pludowski","year":"2013","journal-title":"Autoimmun Rev"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"111","DOI":"10.3390\/nu5010111","article-title":"Vitamin D effects on skeletal and extraskeletal health and the need for supplementation","volume":"5","author":"M Wacker","year":"2013","journal-title":"Nutrients"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1007\/s12016-012-8342-y","article-title":"Vitamin D in systemic and organ-specific autoimmune diseases","volume":"45","author":"N Agmon-Levin","year":"2013","journal-title":"Clin Rev Allergy Immunol"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1136\/ard.2009.120329","article-title":"Serum concentrations of 25-OH vitamin D in patients with systemic lupus erythematosus (SLE) are inversely related to disease activity: is it time to routinely supplement patients with SLE with vitamin D?","volume":"69","author":"H Amital","year":"2010","journal-title":"Ann Rheum Dis"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"2143","DOI":"10.1002\/art.22722","article-title":"Association between serum vitamin D metabolite levels and disease activity in patients with early inflammatory polyarthritis","volume":"56","author":"S Patel","year":"2007","journal-title":"Arthritis Rheum"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"2832","DOI":"10.1001\/jama.296.23.2832","article-title":"Serum 25-hydroxyvitamin D levels and risk of multiple sclerosis","volume":"296","author":"KL Munger","year":"2006","journal-title":"JAMA"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.jaut.2007.09.002","article-title":"Evidence for association between vitamin D receptor BsmI polymorphism and type 1 diabetes in Japanese","volume":"30","author":"A Shimada","year":"2008","journal-title":"J Autoimmun"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1007\/BF02207673","article-title":"Reduced bone mass and normal calcium metabolism in systemic sclerosis with and without calcinosis","volume":"14","author":"O Di Munno","year":"1995","journal-title":"Clin Rheumatol"},{"key":"ref13","first-page":"A118","article-title":"The Rapid Assessment of Physical Activity (RAPA) among older adults","volume":"3","author":"TD Topolski","year":"2006","journal-title":"Prev Chronic Dis"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1136\/annrheumdis-2013-203301","article-title":"DETECT study group. Evidence-based detection of pulmonary arterial hypertension in systemic sclerosis: the DETECT study","volume":"73","author":"JG Coghlan","year":"2014","journal-title":"Ann Rheum Dis"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"1881","DOI":"10.3899\/jrheum.130032","article-title":"Low bone density in systemic sclerosis. A systematic review","volume":"40","author":"MA Omair","year":"2013","journal-title":"The Journal of rheumatology"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1007\/BF02208027","article-title":"Osteopenia in systemic sclerosis. Evidence of a participating role of earlier menopause","volume":"10","author":"G La Montagna","year":"1991","journal-title":"Clin Rheumatol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"e66991","DOI":"10.1371\/journal.pone.0066991","article-title":"Bone mineral density, bone turnover markers and fractures in patients with systemic sclerosis: a case control study","volume":"8","author":"M Atteritano","year":"2013","journal-title":"PLoS One"},{"key":"ref18","first-page":"180","article-title":"Prognostic factors of low bone mineral density in systemic sclerosis","volume":"23","author":"PD Sampaio-Barros","year":"2005","journal-title":"Clin Exp Rheumatol"},{"key":"ref19","first-page":"313","article-title":"Clinical determinants of bone mass and bone ultrasonometry in patients with systemic sclerosis","volume":"22","author":"B Frediani","year":"2004","journal-title":"Clin Exp Rheumatol"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1080\/03009740600704296","article-title":"Systemic sclerosis and bone loss: the role of the disease and body composition","volume":"35","author":"RB Souza","year":"2006","journal-title":"Scand J Rheumatol"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"1348","DOI":"10.1093\/rheumatology\/ken203","article-title":"Hypovitaminosis D among rheumatologic outpatients in clinical practice","volume":"47","author":"M Mouyis","year":"2008","journal-title":"Rheumatology"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1136\/ard.2007.072736","article-title":"Vitamin D intake and risks of systemic lupus erythematosus and rheumatoid arthritis in women","volume":"67","author":"KH Costenbader","year":"2008","journal-title":"Ann Rheum Dis"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.autrev.2005.05.009","article-title":"Vitamin D deficiency in systemic lupus erythematosus","volume":"5","author":"DL Kamen","year":"2006","journal-title":"Autoimmun Rev"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"491","DOI":"10.3899\/jrheum.090797","article-title":"Vitamin D and the immune system","volume":"37","author":"N Maruotti","year":"2010","journal-title":"J Rheumatol"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.autrev.2010.11.006","article-title":"Vitamin D insufficiency in a large MCTD population","volume":"10","author":"A Hajas","year":"2011","journal-title":"Autoimmun Rev"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1007\/s10067-010-1478-3","article-title":"Very low levels of vitamin D in systemic sclerosis patients","volume":"29","author":"P Caramaschi","year":"2010","journal-title":"Clin Rheumatol"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1016\/j.autrev.2011.02.002","article-title":"Serum 25-OH vitamin D concentrations are linked with various clinical aspects in patients with systemic sclerosis: a retrospective cohort study and review of the literature","volume":"10","author":"Y Arnson","year":"2011","journal-title":"Autoimmun Rev"},{"issue":"127","key":"ref28","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1183\/09059180.00005512","article-title":"Scleroderma lung disease","volume":"22","author":"JJ Solomon","year":"2013","journal-title":"Eur Respir Rev"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"3143","DOI":"10.1007\/s00296-011-2150-1","article-title":"Bone density in Moroccan women with systemic scleroderma and its relationships with disease-related parameters and vitamin D status","volume":"32","author":"Yacoub Y Ibn","year":"2012","journal-title":"Rheumatol Int"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1093\/rheumatology\/kep226","article-title":"Small intestinal bacterial overgrowth in systemic sclerosis","volume":"48","author":"I Marie","year":"2009","journal-title":"Rheumatology (Oxford)"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"1871","DOI":"10.1002\/acr.21761","article-title":"Increased risk of osteoporosis and fracture in women with systemic sclerosis: a comparative study with rheumatoid arthritis","volume":"64","author":"J Avouac","year":"2012","journal-title":"Arthritis Care Res"},{"key":"ref32","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1677\/JOE-08-0241","article-title":"Vitamin D reduces the expression of collagen and key profibrotic factors by inducing an antifibrotic phenotype in mesenchymal multipotent cells","volume":"200","author":"JN Artaza","year":"2009","journal-title":"J Endocrinol"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.jsbmb.2009.11.004","article-title":"Vitamin D inhibition of pro-fibrotic effects on transforming growth factor \u03b21 in lung fibroblasts and epithelial cells","volume":"118","author":"AM Ramirez","year":"2010","journal-title":"J Steroid Biochem Mol Biol"}],"updated-by":[{"DOI":"10.1371\/journal.pone.0142748","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2015,11,6]],"date-time":"2015-11-06T00:00:00Z","timestamp":1446768000000}}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0137912","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,30]],"date-time":"2019-08-30T17:10:20Z","timestamp":1567185020000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0137912"}},"subtitle":[],"editor":[{"given":"Shervin","family":"Assassi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2015,9,16]]},"references-count":33,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2015,9,16]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0137912","relation":{"correction":[{"id-type":"doi","id":"10.1371\/journal.pone.0142748","asserted-by":"object"}]},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,9,16]]}}}