{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T12:45:43Z","timestamp":1785329143395,"version":"3.55.0"},"reference-count":26,"publisher":"Public Library of Science (PLoS)","issue":"12","license":[{"start":{"date-parts":[[2015,12,2]],"date-time":"2015-12-02T00:00:00Z","timestamp":1449014400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0143367","type":"journal-article","created":{"date-parts":[[2015,12,2]],"date-time":"2015-12-02T18:59:53Z","timestamp":1449082793000},"page":"e0143367","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":38,"title":["Neutrophil Gelatinase Associated Lipocalin (NGAL) in Leptospirosis Acute Kidney Injury: A Multicenter Study in Thailand"],"prefix":"10.1371","volume":"10","author":[{"given":"Nattachai","family":"Srisawat","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kearkiat","family":"Praditpornsilpa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kanitha","family":"Patarakul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malee","family":"Techapornrung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tinnapop","family":"Daraswang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theerapon","family":"Sukmark","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamol","family":"Khositrangsikun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Apinya","family":"Fakthongyoo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petchdee","family":"Oranrigsupak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laksamon","family":"Praderm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ummarit","family":"Suwattanasilpa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sadudee","family":"Peerapornratana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Passisd","family":"Loahaveeravat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nattachai","family":"Suwachittanont","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thaksa-on","family":"Wirotwan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chayanat","family":"Phonork","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarinya","family":"Kumpunya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khajohn","family":"Tiranathanagul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chintana","family":"Chirathaworn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Somchai","family":"Eiam-ong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kriang","family":"Tungsanga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Visith","family":"Sitprija","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John A.","family":"Kellum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natavudh","family":"Townamchai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Thai Lepto-AKI study group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2015,12,2]]},"reference":[{"issue":"4","key":"ref1","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.ijid.2007.09.011","article-title":"The globalization of leptospirosis: worldwide incidence trends","volume":"12","author":"G Pappas","year":"2008","journal-title":"Int J Infect Dis"},{"issue":"3","key":"ref2","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1111\/j.1440-1797.2010.01391.x","article-title":"RIFLE and Acute Kidney Injury Network classifications predict mortality in leptospirosis-associated acute kidney injury","volume":"16","author":"GB Silva J\u00fanior","year":"2001","journal-title":"Nephrology (Carlton)"},{"issue":"6","key":"ref3","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1097\/MCC.0b013e32834cd349","article-title":"Acute kidney injury: definition, epidemiology, and outcome","volume":"17","author":"N Srisawat","year":"2011","journal-title":"Curr Opin Crit Care"},{"issue":"6","key":"ref4","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1038\/ki.2009.502","article-title":"Acute kidney injury in non-severe pneumonia is associated with an increased immune response and lower survival","volume":"77","author":"R Murugan","year":"2010","journal-title":"Kidney Int"},{"issue":"4","key":"ref5","first-page":"400","article-title":"Leptospirosis-associated acute kidney injury","volume":"32","author":"F Ede","year":"2010","journal-title":"J Bras Nefrol"},{"issue":"3","key":"ref6","doi-asserted-by":"crossref","first-page":"665","DOI":"10.2215\/CJN.04010907","article-title":"Urine NGAL predicts severity of acute kidney injury after cardiac surgery: a prospective study","volume":"3","author":"M Bennett","year":"2008","journal-title":"Clin J Am Soc Nephrol"},{"issue":"5","key":"ref7","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1038\/ki.2011.160","article-title":"Plasma neutrophil gelatinase-associated lipocalin predicts recovery from acute kidney injury following community-acquired pneumonia","volume":"80","author":"N Srisawat","year":"2011","journal-title":"Kidney Int"},{"issue":"8","key":"ref8","doi-asserted-by":"crossref","first-page":"1815","DOI":"10.2215\/CJN.11261210","article-title":"Urinary biomarkers and renal recovery in critically ill patients with renal support","volume":"6","author":"N Srisawat","year":"2011","journal-title":"Clin J Am Soc Nephrol"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"611","DOI":"10.4269\/ajtmh.14-0232","article-title":"Endothelial glycocalyx damage is associated with leptospirosis acute kidney injury","volume":"92","author":"AB Lib\u00f3rio","year":"2015","journal-title":"Am J Trop Med Hyg"},{"issue":"Suppl 2","key":"ref10","first-page":"1","article-title":"Acute Kidney Injury Work Group. KDIGO Clinical Practice Guideline for Acute Kidney Injury","year":"2012","journal-title":"Kidney Int"},{"key":"ref11","unstructured":"Human Leptospirosis Guidance for Diagnosis, Surveillance and Control. WHO guideline 2003"},{"issue":"2","key":"ref12","first-page":"91","article-title":"The Cut-Off Values for Single Serum of Leptospirosis Detection by Microscopic Agglutination Test","volume":"51","author":"W Petkanchanapong","year":"2009","journal-title":"Bull Dept Med Sci"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"R204","DOI":"10.1186\/cc2872","article-title":"Acute Dialysis Quality Initiative workgroup. Acute renal failure\u2014definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group","volume":"8","author":"R Bellomo","year":"2004","journal-title":"Crit Care"},{"issue":"6","key":"ref14","doi-asserted-by":"crossref","first-page":"R127","DOI":"10.1186\/cc6192","article-title":"Plasma neutrophil gelatinase-associated lipocalin predicts acute kidney injury, morbidity and mortality after pediatric cardiac surgery: a prospective uncontrolled cohort study","volume":"11","author":"CL Dent","year":"2007","journal-title":"Crit Care"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1016\/S0140-6736(05)74811-X","article-title":"Neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker for acute renal injury after cardiac surgery","volume":"365","author":"J Mishra","year":"2005","journal-title":"Lancet"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"2089","DOI":"10.1007\/s00467-007-0601-4","article-title":"NGAL is an early predictive biomarker of contrast-induced nephropathy in children","volume":"22","author":"R Hirsch","year":"2007","journal-title":"Pediatr Nephrol"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1038\/ki.2008.341","article-title":"Urinary cystatin C as an early biomarker of acute kidney injury following adult cardiothoracic surgery","volume":"74","author":"JL Koyner","year":"2008","journal-title":"Kidney Int"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1097\/CCM.0b013e318169245a","article-title":"Serum neutrophil gelatinase associated lipocalin (NGAL) as a marker of acute kidney injury in critically ill children with septic shock","volume":"36","author":"DS Wheeler","year":"2008","journal-title":"Crit Care Med"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"176.e1","DOI":"10.1016\/j.jcrc.2009.05.010","article-title":"Plasma neutrophil gelatinase associated lipocalin is an early marker of acute kidney injury in adult critically ill patients: a prospective study","volume":"25","author":"JM Constantin","year":"2010","journal-title":"J Crit Care"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1097\/CCM.0b013e318195846e","article-title":"Novel and conventional serum biomarkers predicting acute kidney injury in adult cardiac surgery\u2013a prospective cohort study","volume":"37","author":"A Haase-Fielitz","year":"2009","journal-title":"Crit Care Med"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1097\/FJC.0b013e31819d6139","article-title":"Rapid detection of acute kidney injury by plasma and urinary neutrophil gelatinase-associated lipocalin after cardiopulmonary bypass","volume":"53","author":"SM Tuladhar","year":"2009","journal-title":"J Cardiovasc Pharmacol"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1097\/01.ASN.0000014692.19351.52","article-title":"Refining predictive models in critically ill patients with acute renal failure","volume":"13","author":"RL Mehta","year":"2002","journal-title":"J Am Soc Nephrol"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"2282","DOI":"10.1093\/ndt\/gfh364","article-title":"Re-evaluation and modification of the Stuivenberg Hospital Acute Renal Failure (SHARF) scoring system for the prognosis of acute renal failure: an independent multicentre, prospective study","volume":"19","author":"RL Lins","year":"2004","journal-title":"Nephrol Dial Transplant"},{"issue":"6","key":"ref24","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1053\/j.ajkd.2009.07.020","article-title":"Accuracy of neutrophil gelatinase-associated lipocalin (NGAL) in diagnosis and prognosis in acute kidney injury: a systematic review and meta-analysis","volume":"54","author":"M Haase","year":"2009","journal-title":"Am J Kidney Dis"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1681\/ASN.2006080882","article-title":"Dual action of neutrophil gelatinase-associated lipocalin","volume":"18","author":"KM Schmidt-Ott","year":"2007","journal-title":"J Am Soc Nephrol"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1038\/sj.ki.5002165","article-title":"Neutrophil gelatinase-associated lipocalin as the real-time indicator of active kidney damage","volume":"71","author":"K Mori","year":"2007","journal-title":"Kidney Int"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0143367","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,10,23]],"date-time":"2018-10-23T19:59:06Z","timestamp":1540324746000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0143367"}},"subtitle":[],"editor":[{"given":"Antonio Carlos","family":"Seguro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2015,12,2]]},"references-count":26,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2015,12,2]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0143367","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,12,2]]}}}