{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T10:53:46Z","timestamp":1784804026366,"version":"3.55.0"},"reference-count":80,"publisher":"Public Library of Science (PLoS)","issue":"12","license":[{"start":{"date-parts":[[2015,12,1]],"date-time":"2015-12-01T00:00:00Z","timestamp":1448928000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0143916","type":"journal-article","created":{"date-parts":[[2015,12,1]],"date-time":"2015-12-01T20:17:51Z","timestamp":1449001071000},"page":"e0143916","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":9,"title":["The Burkholderia pseudomallei Proteins BapA and BapC Are Secreted TTSS3 Effectors and BapB Levels Modulate Expression of BopE"],"prefix":"10.1371","volume":"10","author":[{"given":"Puthayalai","family":"Treerat","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priyangi","family":"Alwis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanya","family":"D\u2019Cruze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meabh","family":"Cullinane","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamunarani","family":"Vadivelu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodney J.","family":"Devenish","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Prescott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ben","family":"Adler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John D.","family":"Boyce","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2015,12,1]]},"reference":[{"key":"ref1","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1038\/nrmicro1385","article-title":"Melioidosis: insights into the pathogenicity of <italic>Burkholderia pseudomallei<\/italic>","volume":"4","author":"WJ Wiersinga","year":"2006","journal-title":"Nat Rev Micro"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1128\/CMR.18.2.383-416.2005","article-title":"Melioidosis: epidemiology, pathophysiology, and management","volume":"18","author":"AC Cheng","year":"2005","journal-title":"Clin Microbiol Rev"},{"key":"ref3","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1146\/annurev.micro.112408.134030","article-title":"Molecular insights into <italic>Burkholderia pseudomallei<\/italic> and <italic>Burkholderia mallei<\/italic> pathogenesis","volume":"64","author":"EE Galyov","year":"2010","journal-title":"Annu Rev Microbiol"},{"key":"ref4","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1097\/01.qco.0000244046.31135.b3","article-title":"Melioidosis","volume":"19","author":"SJ Peacock","year":"2006","journal-title":"Curr Opin Infect Dis"},{"key":"ref5","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1128\/JCM.43.2.970-972.2005","article-title":"Cutaneous melioidosis in a man who was taken as a prisoner of war by the Japanese during World War II","volume":"43","author":"V Ngauy","year":"2005","journal-title":"J Clin Microbiol"},{"key":"ref6","doi-asserted-by":"crossref","first-page":"3027","DOI":"10.1073\/pnas.0535335100","article-title":"Type III secretion systems and bacterial flagella: insights into their function from structural similarities","volume":"100","author":"AJ Blocker","year":"2003","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref7","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1128\/CMR.00013-07","article-title":"Type III secretion systems and disease","volume":"20","author":"B Coburn","year":"2007","journal-title":"Clin Microbiol Rev"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1099\/jmm.0.45661-0","article-title":"Role of quorum sensing in the pathogenicity of <italic>Burkholderia pseudomallei<\/italic>","volume":"53","author":"RL Ulrich","year":"2004","journal-title":"J Med Microbiol"},{"key":"ref9","doi-asserted-by":"crossref","first-page":"3659","DOI":"10.1128\/IAI.01351-10","article-title":"Role for the <italic>Burkholderia pseudomallei<\/italic> type three secretion system cluster 1 <italic>bpscN<\/italic> gene in virulence","volume":"79","author":"T D'Cruze","year":"2011","journal-title":"Infect Immun"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1146\/annurev.micro.54.1.735","article-title":"Assembly and function of type III secretory systems","volume":"54","author":"GR Cornelis","year":"2000","journal-title":"Annu Rev Microbiol"},{"key":"ref11","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1099\/0022-1317-50-2-116","article-title":"Type III secretion systems and pathogenicity islands","volume":"50","author":"C Winstanley","year":"2001","journal-title":"J Med Microbiol"},{"key":"ref12","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1038\/nrmicro1526","article-title":"The type III secretion injectisome","volume":"4","author":"GR Cornelis","year":"2006","journal-title":"Nat Rev Microbiol"},{"key":"ref13","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/j.tim.2010.09.002","article-title":"Unraveling type III secretion systems in the highly versatile <italic>Burkholderia pseudomallei<\/italic>","volume":"18","author":"GW Sun","year":"2010","journal-title":"Trends Microbiol"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"6507","DOI":"10.1073\/pnas.0708344105","article-title":"What&apos;s the point of the type III secretion system needle?","volume":"105","author":"AJ Blocker","year":"2008","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref15","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1038\/nature05272","article-title":"Protein delivery into eukaryotic cells by type III secretion machines","volume":"444","author":"JE Galan","year":"2006","journal-title":"Nature"},{"key":"ref16","doi-asserted-by":"crossref","first-page":"2669","DOI":"10.1099\/mic.0.27146-0","article-title":"Attenuated virulence and protective efficacy of a <italic>Burkholderia pseudomallei bsa<\/italic> type III secretion mutant in murine models of melioidosis","volume":"150","author":"MP Stevens","year":"2004","journal-title":"Microbiology"},{"key":"ref17","doi-asserted-by":"crossref","first-page":"170","DOI":"10.3389\/fmicb.2011.00170","article-title":"Strategies for intracellular survival of <italic>Burkholderia pseudomallei<\/italic>","volume":"2","author":"EM Allwood","year":"2011","journal-title":"Front Microbiol"},{"key":"ref18","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1111\/j.1574-6976.2009.00189.x","article-title":"The molecular and cellular basis of pathogenesis in melioidosis: how does <italic>Burkholderia pseudomallei<\/italic> cause disease?","volume":"33","author":"NR Lazar Adler","year":"2009","journal-title":"FEMS Microbiol Rev"},{"key":"ref19","doi-asserted-by":"crossref","first-page":"2991","DOI":"10.1128\/IAI.00263-08","article-title":"<italic>Burkholderia pseudomallei<\/italic> type III secretion system mutants exhibit delayed vacuolar escape phenotypes in RAW 264.7 murine macrophages","volume":"76","author":"MN Burtnick","year":"2008","journal-title":"Infect Immun"},{"key":"ref20","doi-asserted-by":"crossref","first-page":"e17852","DOI":"10.1371\/journal.pone.0017852","article-title":"The <italic>Burkholderia pseudomallei<\/italic> type III secretion system and BopA are required for evasion of LC3-associated phagocytosis","volume":"6","author":"L Gong","year":"2011","journal-title":"PLoS ONE"},{"key":"ref21","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1007\/s00203-008-0413-3","article-title":"Inactivation of <italic>Burkholderia pseudomallei bsaQ<\/italic> results in decreased invasion efficiency and delayed escape of bacteria from endocytic vesicles","volume":"190","author":"V Muangsombut","year":"2008","journal-title":"Arch Microbiol"},{"key":"ref22","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1111\/j.1574-6968.2011.02359.x","article-title":"BopC is a type III secreted effector protein of <italic>Burkholderia pseudomallei<\/italic>","volume":"323","author":"S Muangman","year":"2011","journal-title":"FEMS Microbiol Lett"},{"key":"ref23","doi-asserted-by":"crossref","first-page":"5377","DOI":"10.1128\/IAI.68.9.5377-5384.2000","article-title":"<italic>Burkholderai pseudomallei<\/italic> induces cell fusion and actin-associated membrane protrusion: a possible mechanism for cell-to-cell spreading","volume":"68","author":"W Kespichayawattana","year":"2000","journal-title":"Infect Immun"},{"key":"ref24","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1111\/j.1462-5822.2005.00569.x","article-title":"Caspase-1 dependent macrophage death induced by <italic>Burkholderia pseudomallei<\/italic>","volume":"7","author":"GW Sun","year":"2005","journal-title":"Cell Microbiol"},{"key":"ref25","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1111\/j.1365-2958.2010.07124.x","article-title":"Identification of a regulatory cascade controlling type III secretion system 3 gene expression in <italic>Burkholderia pseudomallei<\/italic>","volume":"76","author":"GW Sun","year":"2010","journal-title":"Mol Microbiol"},{"key":"ref26","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1046\/j.1365-2958.2002.03190.x","article-title":"An Inv\/Mxi-Spa-like type III protein secretion system in <italic>Burkholderia pseudomallei<\/italic> modulates intracellular behaviour of the pathogen","volume":"46","author":"MP Stevens","year":"2002","journal-title":"Mol Microbiol"},{"key":"ref27","doi-asserted-by":"crossref","first-page":"4992","DOI":"10.1128\/JB.185.16.4992-4996.2003","article-title":"A <italic>Burkholderia pseudomallei<\/italic> type III secreted protein, BopE, facilitates bacterial invasion of epithelial cells and exhibits guanine nucleotide exchange factor activity","volume":"185","author":"MP Stevens","year":"2003","journal-title":"J Bacteriol"},{"key":"ref28","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.femsle.2004.10.045","article-title":"Type III secretion system cluster 3 is required for maximal virulence of <italic>Burkholderia pseudomallei<\/italic> in a hamster infection model","volume":"242","author":"J Warawa","year":"2005","journal-title":"FEMS Microbiol Lett"},{"key":"ref29","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1093\/infdis\/jiu492","article-title":"Functional characterizations of effector protein BipC, a type III secretion system protein, in <italic>Burkholderia pseudomallei<\/italic> pathogenesis","volume":"211","author":"W-T Kang","year":"2015","journal-title":"J Infect Dis"},{"key":"ref30","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.1128\/IAI.03070-14","article-title":"<italic>Burkholderia pseudomallei<\/italic> type III secretion system cluster 3 ATPase BsaS: a chemotherapeutic target for small molecule ATPase inhibitors","volume":"83","author":"L Gong","year":"2015","journal-title":"Infect Immun"},{"key":"ref31","doi-asserted-by":"crossref","first-page":"744","DOI":"10.4161\/auto.6246","article-title":"Stimulation of autophagy suppresses the intracellular survival of <italic>Burkholderia pseudomallei<\/italic> in mammalian cell lines","volume":"4","author":"M Cullinane","year":"2008","journal-title":"Autophagy"},{"key":"ref32","article-title":"Quantitative proteomic analysis of <italic>Burkholderia pseudomallei<\/italic> Bsa Type III secretion system effectors using hyper-secreting mutants","author":"CW Vander Broek","year":"2015","journal-title":"Mol Cell Proteomics"},{"key":"ref33","doi-asserted-by":"crossref","first-page":"14240","DOI":"10.1073\/pnas.0403302101","article-title":"Genomic plasticity of the causative agent of melioidosis, <italic>Burkholderia pseudomallei<\/italic>","volume":"101","author":"MT Holden","year":"2004","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref34","doi-asserted-by":"crossref","first-page":"2101","DOI":"10.1128\/JB.183.6.2101-2110.2001","article-title":"Mobilization function of the pBHR1 plasmid, a derivative of the broad-host-range plasmid pBBR1","volume":"183","author":"CY Szpirer","year":"2001","journal-title":"J Bacteriol"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1128\/jb.178.5.1310-1319.1996","article-title":"Flagellin A is essential for the virulence of <italic>Vibrio anguillarum<\/italic>","volume":"178","author":"DL Milton","year":"1996","journal-title":"J Bacteriol"},{"key":"ref36","doi-asserted-by":"crossref","first-page":"6568","DOI":"10.1128\/jb.172.11.6568-6572.1990","article-title":"Mini-Tn<italic>5<\/italic> transposon derivatives for insertion mutagenesis, promoter probing, and chromosomal insertion of cloned DNA in gram-negative eubacteria","volume":"172","author":"V de Lorenzo","year":"1990","journal-title":"J Bacteriol"},{"key":"ref37","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/j.mimet.2008.12.007","article-title":"Facile construction of unmarked deletion mutants in <italic>Burkholderia pseudomallei<\/italic> using <italic>sacB<\/italic> counter-selection in sucrose-resistant and sucrose-sensitive isolates","volume":"76","author":"C-A Logue","year":"2009","journal-title":"J Microbiol Methods"},{"key":"ref38","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1007\/978-1-60327-412-8_14","article-title":"Tracking the secretion of fluorescently labeled type III effectors from single bacteria in real time","volume":"619","author":"N Simpson","year":"2010","journal-title":"Methods Mol Biol"},{"key":"ref39","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1006\/abio.1999.4149","article-title":"Quantitative protein precipitation from guanidine hydrochloride-containing solutions by sodium deoxycholate\/trichloroacetic acid","volume":"271","author":"U Arnold","year":"1999","journal-title":"Anal Biochem"},{"key":"ref40","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/0003-2697(92)90573-P","article-title":"Efficient precipitation and accurate quantitation of detergent-solubilized membrane proteins","volume":"205","author":"Y-C Chang","year":"1992","journal-title":"Anal Biochem"},{"key":"ref41","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1038\/nmeth804","article-title":"Secretion of type III effectors into host cells in real time","volume":"2","author":"J Enninga","year":"2005","journal-title":"Nat Meth"},{"key":"ref42","doi-asserted-by":"crossref","first-page":"5848","DOI":"10.1128\/IAI.00755-06","article-title":"Effects of temperature on gene expression patterns in <italic>Leptospira interrogans<\/italic> serovar Lai as assessed by whole-genome microarrays","volume":"74","author":"M Lo","year":"2006","journal-title":"Infect Immun"},{"key":"ref43","doi-asserted-by":"crossref","first-page":"5440","DOI":"10.1128\/IAI.71.9.5440-5446.2003","article-title":"Signature-tagged mutagenesis of <italic>Pasteurella multocida<\/italic> identifies mutants displaying differential virulence characteristics in mice and chickens","volume":"71","author":"M Harper","year":"2003","journal-title":"Infect Immun"},{"key":"ref44","doi-asserted-by":"crossref","first-page":"3436","DOI":"10.1128\/IAI.72.6.3436-3443.2004","article-title":"A heptosyltransferase mutant of <italic>Pasteurella multocida<\/italic> produces a truncated lipopolysaccharide structure and is attenuated in virulence","volume":"72","author":"M Harper","year":"2004","journal-title":"Infect Immun"},{"key":"ref45","doi-asserted-by":"crossref","first-page":"1666","DOI":"10.1038\/nprot.2010.129","article-title":"Fluorescent labeling of tetracysteine-tagged proteins in intact cells","volume":"5","author":"C Hoffmann","year":"2010","journal-title":"Nat Protoc"},{"key":"ref46","first-page":"209","article-title":"Protein labeling with FlAsH and ReAsH","volume":"356","author":"T Machleidt","year":"2006","journal-title":"Methods Mol Biol"},{"key":"ref47","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1007\/s004240100619","article-title":"The protein-labeling reagent FlASH-EDT<sub>2<\/sub> binds not only to CCXXCC motifs but also non-specifically to endogenous cysteine-rich proteins","volume":"442","author":"K Stroffekova","year":"2001","journal-title":"Pflugers Arch"},{"key":"ref48","doi-asserted-by":"crossref","first-page":"12095","DOI":"10.1073\/pnas.1107183108","article-title":"Dissection of the <italic>Burkholderia<\/italic> intracellular life cycle using a photothermal nanoblade","volume":"108","author":"CT French","year":"2011","journal-title":"Proc Natl Acad Sci U S A"},{"key":"ref49","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1128\/IAI.64.3.782-790.1996","article-title":"Intracellular survival of <italic>Burkholderia pseudomallei<\/italic>","volume":"64","author":"AL Jones","year":"1996","journal-title":"Infect Immun"},{"key":"ref50","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1111\/j.1574-6976.2011.00271.x","article-title":"Functional domains and motifs of bacterial type III effector proteins and their roles in infection","volume":"35","author":"P Dean","year":"2011","journal-title":"FEMS Microbiol Rev"},{"key":"ref51","doi-asserted-by":"crossref","first-page":"1462","DOI":"10.1111\/j.1462-5822.2009.01360.x","article-title":"Imaging the assembly, structure and activity of type III secretion systems","volume":"11","author":"J Enninga","year":"2009","journal-title":"Cell Microbiol"},{"key":"ref52","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1126\/science.1124618","article-title":"The fluorescent toolbox for assessing protein location and function","volume":"312","author":"BNG Giepmans","year":"2006","journal-title":"Science"},{"key":"ref53","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1016\/j.chembiol.2008.04.014","article-title":"Quantification of real-time <italic>Salmonella<\/italic> effector type III secretion kinetics reveals differential secretion rates for SopE2 and SptP","volume":"15","author":"SB VanEngelenburg","year":"2008","journal-title":"Chem Biol"},{"key":"ref54","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1139\/O07-109","article-title":"Acyl carrier protein: structure-function relationships in a conserved multifunctional protein family","volume":"85","author":"DM Byers","year":"2007","journal-title":"Biochem Cell Biol"},{"key":"ref55","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1042\/BJ20100462","article-title":"Current understanding of fatty acid biosynthesis and the acyl carrier protein","volume":"430","author":"DI Chan","year":"2010","journal-title":"Biochem J"},{"key":"ref56","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1126\/science.281.5374.269","article-title":"Specific covalent labeling of recombinant protein molecules inside live cells","volume":"281","author":"BA Griffin","year":"1998","journal-title":"Science"},{"key":"ref57","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1186\/s12866-014-0206-6","article-title":"Characterization and analysis of the <italic>Burkholderia pseudomallei<\/italic> BsaN virulence regulon","volume":"14","author":"Y Chen","year":"2014","journal-title":"BMC Microbiol"},{"key":"ref58","doi-asserted-by":"crossref","first-page":"4332","DOI":"10.1128\/JB.00076-12","article-title":"Effect of <italic>iacP<\/italic> mutation on flagellar phase variation in <italic>Salmonella enterica<\/italic> serovar Typhimurium strain UK-1","volume":"194","author":"JS Eom","year":"2012","journal-title":"J Bacteriol"},{"key":"ref59","doi-asserted-by":"crossref","first-page":"1656","DOI":"10.1104\/pp.109.139089","article-title":"Type III protein secretion in plant pathogenic bacteria","volume":"150","author":"D B\u00fcttner","year":"2009","journal-title":"Plant Physiol"},{"key":"ref60","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1111\/j.1365-2958.2004.04128.x","article-title":"A novel anti-anti-activator mechanism regulates expression of the <italic>Pseudomonas aeruginosa<\/italic> type III secretion system","volume":"53","author":"N Dasgupta","year":"2004","journal-title":"Mol Microbiol"},{"key":"ref61","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1046\/j.1365-2958.2001.02702.x","article-title":"The type III secretion chaperone LcrH co-operates with YopD to establish a negative, regulatory loop for control of Yop synthesis in <italic>Yersinia pseudotuberculosis<\/italic>","volume":"42","author":"MS Francis","year":"2001","journal-title":"Mol Microbiol"},{"key":"ref62","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1038\/nature03554","article-title":"Structural characterization of the molecular platform for type III secretion system assembly","volume":"435","author":"CK Yip","year":"2005","journal-title":"Nature"},{"key":"ref63","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/S1369-5274(02)00002-4","article-title":"The various and varying roles of specific chaperones in type III secretion systems","volume":"6","author":"C Parsot","year":"2003","journal-title":"Curr Opin Microbiol"},{"key":"ref64","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1128\/MMBR.64.4.694-708.2000","article-title":"Coupling of flagellar gene expression to flagellar assembly in <italic>Salmonella enterica<\/italic> serovar Typhimurium and <italic>Escherichia coli<\/italic>","volume":"64","author":"GS Chilcott","year":"2000","journal-title":"Microbiol Mol Biol Rev"},{"key":"ref65","doi-asserted-by":"crossref","first-page":"5546","DOI":"10.1128\/JB.185.18.5546-5554.2003","article-title":"Interactions of FliJ with the <italic>Salmonella<\/italic> type III flagellar export apparatus","volume":"185","author":"GM Fraser","year":"2003","journal-title":"J Bacteriol"},{"key":"ref66","doi-asserted-by":"crossref","first-page":"e34220","DOI":"10.1371\/journal.pone.0034220","article-title":"The flagellar regulator <italic>fliT<\/italic> represses <italic>Salmonella<\/italic> pathogenicity island 1 through <italic>flhDC<\/italic> and <italic>fliZ<\/italic>","volume":"7","author":"C-C Hung","year":"2012","journal-title":"PLoS ONE"},{"key":"ref67","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1128\/MMBR.05017-11","article-title":"Protein export according to schedule: architecture, assembly, and regulation of type III secretion systems from plant- and animal-pathogenic bacteria","volume":"76","author":"D B\u00fcttner","year":"2012","journal-title":"Microbiol Mol Biol Rev"},{"key":"ref68","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1128\/CMR.12.3.405","article-title":"Molecular basis of the interaction of <italic>Salmonella<\/italic> with the intestinal mucosa","volume":"12","author":"KH Darwin","year":"1999","journal-title":"Clin Microbiol Rev"},{"key":"ref69","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1046\/j.1365-2958.2000.01772.x","article-title":"The putative invasion protein chaperone SicA acts together with InvF to activate the expression of <italic>Salmonella typhimurium<\/italic> virulence genes","volume":"35","author":"KH Darwin","year":"2000","journal-title":"Mol Microbiol"},{"key":"ref70","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1111\/j.1365-2958.2005.04823.x","article-title":"A genome-wide screen identifies a <italic>Bordetella<\/italic> type III secretion effector and candidate effectors in other species","volume":"58","author":"EM Panina","year":"2005","journal-title":"Mol Microbiol"},{"key":"ref71","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1007\/s002390010136","article-title":"Identification of four families of peptidoglycan lytic transglycosylases","volume":"52","author":"NT Blackburn","year":"2001","journal-title":"J Mol Evol"},{"key":"ref72","doi-asserted-by":"crossref","first-page":"2371","DOI":"10.1007\/s00018-003-3056-1","article-title":"Lytic transglycosylases in macromolecular transport systems of Gram-negative bacteria","volume":"60","author":"G Koraimann","year":"2003","journal-title":"Cell Mol Life Sci"},{"key":"ref73","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1016\/j.biocel.2007.03.018","article-title":"Lytic transglycosylases: bacterial space-making autolysins","volume":"40","author":"E Scheurwater","year":"2008","journal-title":"Int J Biochem Cell Biol"},{"key":"ref74","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1574-6968.2011.02228.x","article-title":"Maintaining network security: how macromolecular structures cross the peptidoglycan layer","volume":"318","author":"EM Scheurwater","year":"2011","journal-title":"FEMS Microbiol Lett"},{"key":"ref75","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1128\/JB.184.5.1340-1348.2002","article-title":"Two novel type III-secreted proteins of <italic>Xanthomonas campestris<\/italic> pv. vesicatoria are encoded within the <italic>hrp<\/italic> pathogenicity island","volume":"184","author":"L No\u00ebl","year":"2002","journal-title":"J Bacteriol"},{"key":"ref76","doi-asserted-by":"crossref","first-page":"1844","DOI":"10.1128\/JB.182.7.1844-1853.2000","article-title":"Identification of two novel <italic>hrp<\/italic>-associated genes in the <italic>hrp<\/italic> gene cluster of <italic>Xanthomonas oryzae<\/italic> pv. oryzae","volume":"182","author":"W Zhu","year":"2000","journal-title":"J Bacteriol"},{"key":"ref77","doi-asserted-by":"crossref","first-page":"3809","DOI":"10.1128\/AEM.02849-10","article-title":"Hpa2 required by HrpF to translocate <italic>Xanthomonas oryzae<\/italic> transcriptional activator-like effectors into rice for pathogenicity","volume":"77","author":"Y-R Li","year":"2011","journal-title":"Appl Environ Microbiol"},{"key":"ref78","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/0923-2508(96)80267-1","article-title":"Nucleotide sequence of <italic>iagA<\/italic> and <italic>iagB<\/italic> genes involved in invasion of HeLa cells by <italic>Salmonella enterica<\/italic> subsp. <italic>enterica<\/italic> ser. <italic>Typhi<\/italic>","volume":"146","author":"I Miras","year":"1995","journal-title":"Res Microbiol"},{"key":"ref79","doi-asserted-by":"crossref","first-page":"6418","DOI":"10.1128\/JB.00621-10","article-title":"Silent mischief: bacteriophage Mu insertions contaminate products of <italic>Escherichia coli<\/italic> random mutagenesis performed using suicidal transposon delivery plasmids mobilized by broad-host-range RP4 conjugative machinery","volume":"192","author":"L Ferri\u00e8res","year":"2010","journal-title":"J Bacteriol"},{"key":"ref80","doi-asserted-by":"crossref","first-page":"3455","DOI":"10.1099\/mic.0.28141-0","article-title":"Peptidoglycan degradation by specialized lytic transglycosylases associated with type III and type IV secretion systems","volume":"151","author":"D Zahrl","year":"2005","journal-title":"Microbiology"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0143916","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,12]],"date-time":"2020-09-12T04:11:36Z","timestamp":1599883896000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0143916"}},"subtitle":[],"editor":[{"given":"Eric","family":"Cascales","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2015,12,1]]},"references-count":80,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2015,12,1]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0143916","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,12,1]]}}}