{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T05:08:05Z","timestamp":1790399285061,"version":"4.1.0"},"reference-count":60,"publisher":"Public Library of Science (PLoS)","issue":"12","license":[{"start":{"date-parts":[[2015,12,16]],"date-time":"2015-12-16T00:00:00Z","timestamp":1450224000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.plosone.org"],"crossmark-restriction":false},"short-container-title":["PLoS ONE"],"DOI":"10.1371\/journal.pone.0145112","type":"journal-article","created":{"date-parts":[[2015,12,16]],"date-time":"2015-12-16T18:47:24Z","timestamp":1450291644000},"page":"e0145112","update-policy":"https:\/\/doi.org\/10.1371\/journal.pone.corrections_policy","source":"Crossref","is-referenced-by-count":32,"title":["GTPase Activating Protein (Sh3 Domain) Binding Protein 1 Regulates the Processing of MicroRNA-1 during Cardiac Hypertrophy"],"prefix":"10.1371","volume":"10","author":[{"given":"Minzhen","family":"He","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maha","family":"Abdellatif","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danish","family":"Sayed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"340","published-online":{"date-parts":[[2015,12,16]]},"reference":[{"issue":"15","key":"ref1","doi-asserted-by":"crossref","first-page":"3037","DOI":"10.1096\/fasebj.5.15.1835945","article-title":"Regulation of cardiac gene expression during myocardial growth and hypertrophy: molecular studies of an adaptive physiologic response","volume":"5","author":"KR Chien","year":"1991","journal-title":"Faseb J"},{"key":"ref2","first-page":"95","article-title":"Changes in transcriptional activity during myocardial hypertrophy","volume":"39","author":"AF Cutilletta","year":"1979","journal-title":"Tex Rep Biol Med"},{"issue":"5","key":"ref3","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1007\/BF01906981","article-title":"The mechanism of the heart's adaption to prolonged load and dynamics of RNA synthesis in the myocardium","volume":"69","author":"FZ Meerson","year":"1974","journal-title":"Basic Res Cardiol"},{"issue":"8","key":"ref4","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1016\/0022-2828(80)90083-8","article-title":"Regression of myocardial hypertrophy. II. RNA synthesis and RNA polymerase activity","volume":"12","author":"AF Cutilletta","year":"1980","journal-title":"J Mol Cell Cardiol"},{"issue":"8","key":"ref5","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/0022-2828(78)90403-0","article-title":"Muscle and non-muscle cell RNA polymerase activity during the development of myocardial hypertrophy","volume":"10","author":"AF Cutilletta","year":"1978","journal-title":"J Mol Cell Cardiol"},{"issue":"2","key":"ref6","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.cardiores.2004.03.025","article-title":"GATA transcription factors in the developing and adult heart","volume":"63","author":"S Pikkarainen","year":"2004","journal-title":"Cardiovasc Res"},{"issue":"1","key":"ref7","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1161\/01.RES.0000197782.21444.8f","article-title":"Control of cardiac growth by histone acetylation\/deacetylation","volume":"98","author":"J Backs","year":"2006","journal-title":"Circ Res"},{"issue":"2","key":"ref8","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1002\/path.4234","article-title":"Epigenetics and chromatin remodeling in adult cardiomyopathy","volume":"231","author":"SA Mahmoud","year":"2013","journal-title":"J Pathol"},{"issue":"3","key":"ref9","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1097\/MOH.0000000000000040","article-title":"Post-transcriptional gene regulation by HuR and microRNAs in angiogenesis","volume":"21","author":"SH Chang","year":"2014","journal-title":"Curr Opin Hematol"},{"key":"ref10","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1007\/978-1-4939-1221-6_11","article-title":"RNA-binding proteins in heart development","volume":"825","author":"J Giudice","year":"2014","journal-title":"Adv Exp Med Biol"},{"issue":"1","key":"ref11","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1002\/wrna.1197","article-title":"Competition and collaboration between RNA-binding proteins and microRNAs","volume":"5","author":"JJ Ho","year":"2014","journal-title":"Wiley Interdiscip Rev RNA"},{"issue":"19","key":"ref12","doi-asserted-by":"crossref","first-page":"3723","DOI":"10.1016\/j.jmb.2012.11.024","article-title":"Posttranscriptional gene regulation by long noncoding RNA","volume":"425","author":"JH Yoon","year":"2013","journal-title":"J Mol Biol"},{"issue":"5543","key":"ref13","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1126\/science.1065062","article-title":"An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans","volume":"294","author":"NC Lau","year":"2001","journal-title":"Science"},{"issue":"5543","key":"ref14","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1126\/science.1065329","article-title":"An extensive class of small RNAs in Caenorhabditis elegans","volume":"294","author":"RC Lee","year":"2001","journal-title":"Science"},{"issue":"5","key":"ref15","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1016\/0092-8674(93)90529-Y","article-title":"The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14","volume":"75","author":"RC Lee","year":"1993","journal-title":"Cell"},{"issue":"3","key":"ref16","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1152\/physrev.00006.2010","article-title":"MicroRNAs in Development and Disease","volume":"91","author":"D Sayed","year":"2011","journal-title":"Physiol Rev"},{"issue":"16","key":"ref17","doi-asserted-by":"crossref","first-page":"5391","DOI":"10.1093\/nar\/gkn522","article-title":"miR-16 family induces cell cycle arrest by regulating multiple cell cycle genes","volume":"36","author":"Q Liu","year":"2008","journal-title":"Nucleic Acids Res"},{"issue":"6","key":"ref18","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1161\/CIRCRESAHA.109.200451","article-title":"Loss of cardiac microRNA-mediated regulation leads to dilated cardiomyopathy and heart failure","volume":"105","author":"PK Rao","year":"2009","journal-title":"Circ Res"},{"issue":"Pt 14","key":"ref19","doi-asserted-by":"crossref","first-page":"2444","DOI":"10.1242\/jcs.067165","article-title":"Attenuation of microRNA-1 derepresses the cytoskeleton regulatory protein twinfilin-1 to provoke cardiac hypertrophy","volume":"123","author":"Q Li","year":"2010","journal-title":"J Cell Sci"},{"issue":"5","key":"ref20","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1038\/nm1582","article-title":"MicroRNA-133 controls cardiac hypertrophy","volume":"13","author":"A Care","year":"2007","journal-title":"Nat Med"},{"issue":"3","key":"ref21","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1152\/physiolgenomics.00144.2007","article-title":"Altered microRNA expression in human heart disease","volume":"31","author":"S Ikeda","year":"2007","journal-title":"Physiol Genomics"},{"issue":"3","key":"ref22","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1161\/01.RES.0000257913.42552.23","article-title":"MicroRNAs play an essential role in the development of cardiac hypertrophy","volume":"100","author":"D Sayed","year":"2007","journal-title":"Circ Res"},{"issue":"6","key":"ref23","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1016\/j.yjmcc.2007.04.004","article-title":"Expression of microRNAs is dynamically regulated during cardiomyocyte hypertrophy","volume":"42","author":"M Tatsuguchi","year":"2007","journal-title":"J Mol Cell Cardiol"},{"issue":"23","key":"ref24","doi-asserted-by":"crossref","first-page":"2377","DOI":"10.1161\/CIRCULATIONAHA.109.879429","article-title":"Reciprocal regulation of microRNA-1 and insulin-like growth factor-1 signal transduction cascade in cardiac and skeletal muscle in physiological and pathological conditions","volume":"120","author":"L Elia","year":"2009","journal-title":"Circulation"},{"issue":"8","key":"ref25","doi-asserted-by":"crossref","first-page":"2193","DOI":"10.1128\/MCB.01222-08","article-title":"MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes","volume":"29","author":"S Ikeda","year":"2009","journal-title":"Mol Cell Biol"},{"issue":"1","key":"ref26","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1161\/CIRCHEARTFAILURE.114.001660","article-title":"Acute targeting of general transcription factor IIB restricts cardiac hypertrophy via selective inhibition of gene transcription","volume":"8","author":"D Sayed","year":"2015","journal-title":"Circ Heart Fail"},{"issue":"6","key":"ref27","doi-asserted-by":"crossref","first-page":"2561","DOI":"10.1128\/MCB.16.6.2561","article-title":"A Ras-GTPase-activating protein SH3-domain-binding protein","volume":"16","author":"F Parker","year":"1996","journal-title":"Mol Cell Biol"},{"issue":"3","key":"ref28","first-page":"93","article-title":"Identification of a mouse orthologue of the human ras-GAP-SH3-domain binding protein and structural confirmation that these proteins contain an RNA recognition motif","volume":"2","author":"D Kennedy","year":"1996","journal-title":"Biomed Pept Proteins Nucleic Acids"},{"issue":"22","key":"ref29","doi-asserted-by":"crossref","first-page":"7747","DOI":"10.1128\/MCB.21.22.7747-7760.2001","article-title":"RasGAP-associated endoribonuclease G3Bp: selective RNA degradation and phosphorylation-dependent localization","volume":"21","author":"H Tourriere","year":"2001","journal-title":"Mol Cell Biol"},{"issue":"6","key":"ref30","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1083\/jcb.200212128","article-title":"The RasGAP-associated endoribonuclease G3BP assembles stress granules","volume":"160","author":"H Tourriere","year":"2003","journal-title":"J Cell Biol"},{"issue":"27","key":"ref31","doi-asserted-by":"crossref","first-page":"25717","DOI":"10.1074\/jbc.M414266200","article-title":"An alliance between Ras GTPase-activating protein, filamin C, and Ras GTPase-activating protein SH3 domain-binding protein regulates myocyte growth","volume":"280","author":"J Lypowy","year":"2005","journal-title":"J Biol Chem"},{"issue":"6","key":"ref32","first-page":"H2133","article-title":"Increased expression of eukaryotic initiation factor 4E during growth of neonatal rat cardiocytes in vitro","volume":"274","author":"AA Makhlouf","year":"1998","journal-title":"Am J Physiol"},{"issue":"2","key":"ref33","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/S0955-0674(98)80150-6","article-title":"The mRNA 5' cap-binding protein eIF4E and control of cell growth","volume":"10","author":"N Sonenberg","year":"1998","journal-title":"Curr Opin Cell Biol"},{"issue":"14","key":"ref34","doi-asserted-by":"crossref","first-page":"8359","DOI":"10.1074\/jbc.271.14.8359","article-title":"Cooper Gt, McDermott PJ. Translational initiation factor eIF-4E. A link between cardiac load and protein synthesis","volume":"271","author":"H Wada","year":"1996","journal-title":"J Biol Chem"},{"issue":"11","key":"ref35","doi-asserted-by":"crossref","first-page":"7269","DOI":"10.1016\/S0021-9258(18)42515-X","article-title":"Eukaryotic initiation factors-4E and -4F stimulate 5' cap-dependent as well as internal initiation of protein synthesis","volume":"267","author":"GC Scheper","year":"1992","journal-title":"J Biol Chem"},{"issue":"4","key":"ref36","doi-asserted-by":"crossref","first-page":"2546","DOI":"10.1074\/jbc.M112.429449","article-title":"Transcriptional regulation patterns revealed by high resolution chromatin immunoprecipitation during cardiac hypertrophy","volume":"288","author":"D Sayed","year":"2013","journal-title":"J Biol Chem"},{"issue":"8","key":"ref37","doi-asserted-by":"crossref","first-page":"3272","DOI":"10.1091\/mbc.E08-02-0159","article-title":"MicroRNA-21 targets Sprouty2 and promotes cellular outgrowths","volume":"19","author":"D Sayed","year":"2008","journal-title":"Mol Biol Cell"},{"key":"ref38","first-page":"109","article-title":"Methods in Molecular Biology","author":"F Graham","year":"1991"},{"issue":"7","key":"ref39","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1038\/nmeth.2089","article-title":"NIH Image to ImageJ: 25 years of image analysis","volume":"9","author":"CA Schneider","year":"2012","journal-title":"Nat Methods"},{"issue":"2","key":"ref40","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1038\/ng1725","article-title":"The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation","volume":"38","author":"JF Chen","year":"2006","journal-title":"Nat Genet"},{"issue":"1","key":"ref41","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1101\/gr.082701.108","article-title":"Most mammalian mRNAs are conserved targets of microRNAs","volume":"19","author":"RC Friedman","year":"2009","journal-title":"Genome Res"},{"issue":"1","key":"ref42","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.molcel.2007.06.017","article-title":"MicroRNA targeting specificity in mammals: determinants beyond seed pairing","volume":"27","author":"A Grimson","year":"2007","journal-title":"Mol Cell"},{"issue":"1","key":"ref43","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.cell.2004.12.035","article-title":"Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets","volume":"120","author":"BP Lewis","year":"2005","journal-title":"Cell"},{"issue":"11","key":"ref44","doi-asserted-by":"crossref","first-page":"2290","DOI":"10.1261\/rna.1188208","article-title":"A bioinformatics tool for linking gene expression profiling results with public databases of microRNA target predictions","volume":"14","author":"CJ Creighton","year":"2008","journal-title":"Rna"},{"issue":"5","key":"ref45","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1038\/ng1536","article-title":"Combinatorial microRNA target predictions","volume":"37","author":"A Krek","year":"2005","journal-title":"Nat Genet"},{"issue":"20","key":"ref46","doi-asserted-by":"crossref","first-page":"4051","DOI":"10.1038\/sj.emboj.7600385","article-title":"MicroRNA genes are transcribed by RNA polymerase II","volume":"23","author":"Y Lee","year":"2004","journal-title":"Embo J"},{"issue":"5","key":"ref47","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1038\/nrm1644","article-title":"MicroRNA biogenesis: coordinated cropping and dicing","volume":"6","author":"VN Kim","year":"2005","journal-title":"Nat Rev Mol Cell Biol"},{"issue":"7","key":"ref48","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1038\/nsmb1250","article-title":"The multifunctional RNA-binding protein hnRNP A1 is required for processing of miR-18a","volume":"14","author":"S Guil","year":"2007","journal-title":"Nat Struct Mol Biol"},{"issue":"3","key":"ref49","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.molcel.2008.10.013","article-title":"Posttranscriptional regulation of miRNAs harboring conserved terminal loops","volume":"32","author":"G Michlewski","year":"2008","journal-title":"Mol Cell"},{"key":"ref50","article-title":"Functional and molecular insights into KSRP function in mRNA decay","volume":"22","author":"P Briata","year":"2013","journal-title":"Biochim Biophys Acta"},{"issue":"7249","key":"ref51","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1038\/nature08025","article-title":"The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs","volume":"459","author":"M Trabucchi","year":"2009","journal-title":"Nature"},{"issue":"20","key":"ref52","doi-asserted-by":"crossref","first-page":"14263","DOI":"10.1074\/jbc.M114.561902","article-title":"The RNA-binding protein TDP-43 selectively disrupts microRNA-1\/206 incorporation into the RNA-induced silencing complex","volume":"289","author":"IN King","year":"2014","journal-title":"J Biol Chem"},{"issue":"7","key":"ref53","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1038\/nsmb.2067","article-title":"Misregulation of miR-1 processing is associated with heart defects in myotonic dystrophy","volume":"18","author":"F Rau","year":"2011","journal-title":"Nat Struct Mol Biol"},{"issue":"7","key":"ref54","doi-asserted-by":"crossref","first-page":"3956","DOI":"10.1128\/MCB.18.7.3956","article-title":"A novel phosphorylation-dependent RNase activity of GAP-SH3 binding protein: a potential link between signal transduction and RNA stability","volume":"18","author":"IE Gallouzi","year":"1998","journal-title":"Mol Cell Biol"},{"issue":"1","key":"ref55","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1002\/jcb.1277","article-title":"Characterization of G3BPs: tissue specific expression, chromosomal localisation and rasGAP(120) binding studies","volume":"84","author":"D Kennedy","year":"2001","journal-title":"J Cell Biochem"},{"issue":"10","key":"ref56","first-page":"12189","article-title":"Deficiency of G3BP1, the stress granules assembly factor, results in abnormal synaptic plasticity and calcium homeostasis in neurons","volume":"4","author":"S Martin","year":"2013","journal-title":"J Neurochem"},{"issue":"2","key":"ref57","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1111\/gtc.12023","article-title":"Both G3BP1 and G3BP2 contribute to stress granule formation","volume":"18","author":"H Matsuki","year":"2013","journal-title":"Genes Cells"},{"issue":"19","key":"ref58","doi-asserted-by":"crossref","first-page":"8703","DOI":"10.1128\/MCB.25.19.8703-8716.2005","article-title":"Control of fetal growth and neonatal survival by the RasGAP-associated endoribonuclease G3BP","volume":"25","author":"L Zekri","year":"2005","journal-title":"Mol Cell Biol"},{"issue":"Pt 16","key":"ref59","doi-asserted-by":"crossref","first-page":"2685","DOI":"10.1242\/jcs.065920","article-title":"Human G3BP1 interacts with beta-F1-ATPase mRNA and inhibits its translation","volume":"123","author":"AD Ortega","year":"2010","journal-title":"J Cell Sci"},{"issue":"1","key":"ref60","doi-asserted-by":"crossref","first-page":"1476","DOI":"10.1186\/1476-4598-12-156","article-title":"Regulation of PMP22 mRNA by G3BP1 affects cell proliferation in breast cancer cells","volume":"12","author":"S Winslow","year":"2013","journal-title":"Mol Cancer"}],"container-title":["PLOS ONE"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/dx.plos.org\/10.1371\/journal.pone.0145112","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,29]],"date-time":"2022-05-29T13:33:31Z","timestamp":1653831211000},"score":1,"resource":{"primary":{"URL":"https:\/\/dx.plos.org\/10.1371\/journal.pone.0145112"}},"subtitle":[],"editor":[{"given":"Fabio","family":"Martelli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2015,12,16]]},"references-count":60,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2015,12,16]]}},"URL":"https:\/\/doi.org\/10.1371\/journal.pone.0145112","relation":{},"ISSN":["1932-6203"],"issn-type":[{"value":"1932-6203","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,12,16]]}}}