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Prevalence and incidence of selected sexually transmitted infections, Chlamydia trachomatis, Neisseria gonorrhoeae, syphilis and Trichomonas vaginalis. Methods and results used by WHO to generate 2005 estimates [Internet]. 2005 07\/06\/2015 [cited 2015 12\/11\/2015]. 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Situaci\u00f3n de las Infecciones de Transmisi\u00f3n Sexual diferentes al VIH, Colombia 2009\u20132011 2012 [cited 2015 August 11th 2015]. Available from: https:\/\/www.minsalud.gov.co\/salud\/Documents\/observatorio_vih\/documentos\/monitoreo_evaluacion\/1_vigilancia_salud_publica\/a_situacion_epidimiologica\/SITUACION%20DE%20LAS%20INFECCIONES%20DE%20TRANSMISION1.pdf<\/ext-link>."},{"issue":"1","key":"ref9","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1002\/ijc.20970","article-title":"Chlamydia trachomatis infection and persistence of human papillomavirus","volume":"116","author":"I Silins","year":"2005","journal-title":"International journal of cancer Journal international du cancer"},{"issue":"2","key":"ref10","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1007\/s11033-013-2927-2","article-title":"Chlamydia trachomatis infection and human papillomavirus in women with cervical neoplasia in Pernambuco-Brazil","volume":"41","author":"MC Tavares","year":"2014","journal-title":"Molecular biology reports"},{"issue":"3","key":"ref11","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1086\/338569","article-title":"Evidence for Chlamydia trachomatis as a human papillomavirus cofactor in the etiology of invasive cervical cancer in Brazil and the Philippines","volume":"185","author":"JS Smith","year":"2002","journal-title":"The Journal of infectious diseases"},{"issue":"4","key":"ref12","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1007\/s00404-013-3122-3","article-title":"Chlamydia trachomatis infection: implications for HPV status and cervical cancer","volume":"289","author":"J Silva","year":"2014","journal-title":"Archives of gynecology and obstetrics"},{"issue":"6","key":"ref13","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1136\/sti.79.6.474","article-title":"Prevalence and determinants of Chlamydia trachomatis infections in women from Bogota, Colombia","volume":"79","author":"M Molano","year":"2003","journal-title":"Sexually transmitted infections"},{"key":"ref14","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1186\/1471-2334-14-395","article-title":"Persistence, clearance and reinfection regarding six high risk human papillomavirus types in Colombian women: a follow-up study","volume":"14","author":"SC Soto-De Leon","year":"2014","journal-title":"BMC infectious diseases"},{"issue":"3","key":"ref15","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.annepidem.2010.11.003","article-title":"Frequency of human papillomavirus infection, coinfection, and association with different risk factors in Colombia","volume":"21","author":"M Camargo","year":"2011","journal-title":"Annals of epidemiology"},{"issue":"6","key":"ref16","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1590\/S0074-02762002000600027","article-title":"One-tube nested polymerase chain reaction for detection of Chlamydia trachomatis","volume":"97","author":"P Cribb","year":"2002","journal-title":"Memorias do Instituto Oswaldo Cruz"},{"key":"ref17","unstructured":"Deluca GD, Alonso JM, Marin HM, Schelover E, Vicente A. 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